XLOC_016757 (kcnq3)


Basic Information

Item Value
gene id XLOC_016757
gene name kcnq3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 43014379 ~ 43083755 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00032858
AGCAATCATGCGGTCGCGCGGAGAACACGCCCTTCCTCGCGCCTCCCTCTCTGAACGAGGTCCTTAAATGACCCACGACCACTAAGAAGCTCGTGCTTTCCCTGTCCGGATCATGGCATGCGCCCCATCCCGGACTTCCACACGCGCGGCGCCGAGGCTCGAGAGCAGTGAACATGGGGATCAGGTCCAGAAATGCCGCTAACAGCGCCGAGGACTCGCGCGAGCGTAAAAGCGCGCTGGCCGGAGACCTGGAGCAGTGCGCGGGGCAGGAACGGGACGGCGCGCTGCTGCTCGTCGGCTCGGGGAGGGAAGTGGACTTCAAAAGGGGCTCGCAGAACATCGGGCTGCTCGCCAAGACGCCCCTGGGATACACGCGCCCCGTGAAGAGGAATAATATCAGGAAGCGACGGATCCAGAACCTCATTTACGACGCGCTCGAGAGACCACGAGGATGGGCGCTGCTCTACCACGCGTTTGTGTTTCTGATTGTTTTGGGATGTCTGATTCTGTCGATATTAACAACATTCAAAGAGCACGAGAAGGATTCGGCTCACTGGCTGGTGATTctgGAGACGTTTACCATCTTTATTTTTGGAGGTGAGTTTGCGTTGAGGATATGGGCCGCCGGCTGCTGCTGTCGATATAAAGGCTGGAGAGGACGGCTCAAATTCGCCCGCAAACCGCTGTGTGTCCTGGATATTTTTGTTCTGATCGCTTCGGTGCCGGTGGTTGCCGTACGTAATCAGGGAAATGTGTTGGCCACGTCGCTGCGCAGTCTGCGTTTCCTGCAGATCCTCCGGATGCTGCGAATGGACAGACGCGGAGGAACCTGGAAACTGCTGGGATCTGCAATATACACACACAGCAAGGAGCTGATCACAGCGTGGTACATCGGCTTCCTGTCATTGATCCTGGCTTCTTTCCTGGTGTATCTGGTCGAGAAGGACGATGAGACCACAGAGCTCCACAGAGACACTGATGGCCCTTCACCGACACCGGCCCCGCAGGACTTTGACACCTATGCAGACGCCCTCTGGTGGGGACTGATCACTTTGACCACCATCGGTTACGGTGACAAGACCCCAAAGACATGGGCAGGGCGTCTTCTGGCCGGGACCTTCGCTCTTATTGGCGTATCATTCTTTGCACTTCCAGCCGGCATTCTTGGTTCAGGTCTGGCTCTGAAAGTTCAGGAACAGCACAGACAGAAACACTTTGAGAAACGCAGACATCCCGCAGCTTCATTAATACAGGCTGCATGGAGATATTACTCCACCAACCCCGTCAGAGAAGATCTCATCGCCACATGGAGATTCTATGAGACTGTGATCTCTCTGCCATGCTTCAGGAAGGATCCTCTTGAAGTTATGGCCAGGTAAGTCTCTCTctcttgtttttctctctctctctctctcattgcctctctctttctctcttgtttttctctctctcgttgcctctctctttctctcttgtttttctctctctcattgcctctctctttctcagtcACTGTTTTTAAAGACCTCCAGCATCTCAGTGAAGTGTGAGATTAATGAATCTGTGAAATGTGTTTCCTTAAATAACTCCTAATAACCAGCACCTCCATTAATTCAGTGCCAGAGGCGTAATGACCAGCGGTgcgttactgtgtgtgtgtgtgtgtgtgagctcgtTTCTCAGTTCGGGGACATGCGGACAGTACTTTTATATGTGATATTACAGAGTCCATTAGAAAAGAGTGAATTATGGATCACTGATAGATGTGGGTGTCAGTACAGAGCCGAGGGAGAGTTTTAATGGACGGCTGGATGTGTGTGACGTCCGTGTCACTGTCAGGAAAATGATGGGAACTGTTATTAGCGATTTGAGCGTGACGAGCTTTGACAAAGATGGACTGCGTTTATAATAATCGCGAGTATCGGTTGTCCTTGACCTGGACACTGGCCTGACAGTCCATTTATTAAAAGATGAAAGATTTACAGATAGAAACAGAAGGAGAGCCGGATTGAGAGCGGGGCTTGTTTAGACCACCTGACCCGAGACCTGTAATCCATGTTCAGTCCAGATGGGAGATCAGATTACATGCTAATACTGCTAATACACTGCTGCAGGCCACACACCTACGCAAACATACGCAAGGCTAGTTGGCTGGGAAACTTGCAGCCTGACATTATCACTGTTGTGACACACTAAACTACCTCAATTGCCTCAGTTACTCCTCAAGTACTCCTTTAGGTGATTGTAGCTGCTAGCATGCATGCTAACCAGTGTAAACATTACCTGTTGATGCTTCGGTGACAGTTTGCTGCAGAGGATCATGTGGGGTGGCTCATCTCCCATAACAACTTTAAATATACCTTACAGTGTGTGATATTAGCTAAAAAACAGATTTGATGCATTACCTACAAGAtatattaaccctttaactggcTTTGTAATTGTTCGGCTGATGTTTTgactatagtttattattaacataaaacaaaaagccCCTCAAAATTAACTGGACTTCTATT
>TCONS_00032859
CGCATCAGCAATCATGCGGTCGCGCGGAGAACACGCCCTTCCTCGCGCCTCCCTCTCTGAACGAGGTCCTTAAATGACCCACGACCACTAAGAAGCTCGTGCTTTCCCTGTCCGGATCATGGCATGCGCCCCATCCCGGACTTCCACACGCGCGGCGCCGAGGCTCGAGAGCAGTGAACATGGGGATCAGGTCCAGAAATGCCGCTAACAGCGCCGAGGACTCGCGCGAGCGTAAAAGCGCGCTGGCCGGAGACCTGGAGCAGTGCGCGGGGCAGGAACGGGACGGCGCGCTGCTGCTCGTCGGCTCGGGGAGGGAAGTGGACTTCAAAAGGGGCTCGCAGAACATCGGGCTGCTCGCCAAGACGCCCCTGGGATACACGCGCCCCGTGAAGAGGAATAATATCAGGAAGCGACGGATCCAGAACCTCATTTACGACGCGCTCGAGAGACCACGAGGATGGGCGCTGCTCTACCACGCGTTTGTGTTTCTGATTGTTTTGGGATGTCTGATTCTGTCGATATTAACAACATTCAAAGAGCACGAGAAGGATTCGGCTCACTGGCTGGTGATTctgGAGACGTTTACCATCTTTATTTTTGGAGGTGAGTTTGCGTTGAGGATATGGGCCGCCGGCTGCTGCTGTCGATATAAAGGCTGGAGAGGACGGCTCAAATTCGCCCGCAAACCGCTGTGTGTCCTGGATATTTTTGTTCTGATCGCTTCGGTGCCGGTGGTTGCCGTACGTAATCAGGGAAATGTGTTGGCCACGTCGCTGCGCAGTCTGCGTTTCCTGCAGATCCTCCGGATGCTGCGAATGGACAGACGCGGAGGAACCTGGAAACTGCTGGGATCTGCAATATACACACACAGCAAGGAGCTGATCACAGCGTGGTACATCGGCTTCCTGTCATTGATCCTGGCTTCTTTCCTGGTGTATCTGGTCGAGAAGGACGATGAGACCACAGAGCTCCACAGAGACACTGATGGCCCTTCACCGACACCGGCCCCGCAGGACTTTGACACCTATGCAGACGCCCTCTGGTGGGGACTGATCACTTTGACCACCATCGGTTACGGTGACAAGACCCCAAAGACATGGGCAGGGCGTCTTCTGGCCGGGACCTTCGCTCTTATTGGCGTATCATTCTTTGCACTTCCAGCCGGCATTCTTGGTTCAGGTCTGGCTCTGAAAGTTCAGGAACAGCACAGACAGAAACACTTTGAGAAACGCAGACATCCCGCAGCTTCATTAATACAGGCTGCATGGAGATATTACTCCACCAACCCCGTCAGAGAAGATCTCATCGCCACATGGAGATTCTATGAGACTGTGATCTCTCTGCCATGCTTCAG

Function

symbol description
kcnq3 Predicted to enable calmodulin binding activity and delayed rectifier potassium channel activity. Acts upstream of or within chemical synaptic transmission. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in axon initial segment. Predicted to be integral component of membrane. Is expressed in central nervous system; heart; and inner ear. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3).

GO:

id name namespace
GO:0071805 potassium ion transmembrane transport biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:0043194 axon initial segment cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0005516 calmodulin binding molecular_function
GO:0005216 ion channel activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0005251 delayed rectifier potassium channel activity molecular_function
GO:0005267 potassium channel activity molecular_function

KEGG:

id description
ko04725 Cholinergic synapse
ko04040 Ion channels

ZFIN:

id description
ZDB-GENE-070912-301 Predicted to enable calmodulin binding activity and delayed rectifier potassium channel activity. Acts upstream of or within chemical synaptic transmission. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in axon initial segment. Predicted to be integral component of membrane. Is expressed in central nervous system; heart; and inner ear. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3).

Ensembl:

ensembl_id ENSDARG00000060085

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00032858 False 2519 mRNA 0.50 11 43014379 43083749
TCONS_00032859 True 1354 mRNA 0.56 9 43017295 43083755

Neighbor

gene id symbol gene type direction distance location
XLOC_016756 kcnq3 coding downstream 3983 43001512 ~ 43010396 (-)
XLOC_016755 NA coding downstream 27409 42981204 ~ 42986970 (-)
XLOC_016754 NA coding downstream 35767 42962862 ~ 42978612 (-)
XLOC_016753 BX511268.2 coding downstream 52035 42962228 ~ 42962344 (-)
XLOC_016752 oc90 coding downstream 54026 42942552 ~ 42960353 (-)
XLOC_016758 lrrc6 coding upstream 14482 43098237 ~ 43124747 (-)
XLOC_016759 ftr13 coding upstream 44607 43128362 ~ 43130930 (-)
XLOC_016760 ftr14 coding upstream 47392 43131147 ~ 43135700 (-)
XLOC_016761 ftr12 coding upstream 61183 43144938 ~ 43151358 (-)
XLOC_016762 crema coding upstream 75416 43159171 ~ 43196595 (-)
XLOC_016751 NA non-coding downstream 78141 42935881 ~ 42936238 (-)
XLOC_016749 NA non-coding downstream 242401 42719037 ~ 42771978 (-)
XLOC_016763 NA non-coding upstream 294347 43378102 ~ 43379093 (-)
XLOC_016764 CABZ01058723.1 non-coding upstream 425747 43509502 ~ 43517018 (-)
XLOC_016766 NA non-coding upstream 483390 43567145 ~ 43571760 (-)
XLOC_016770 NA non-coding upstream 545998 43629753 ~ 43630083 (-)
XLOC_016786 BX323035.1 non-coding upstream 1439101 44522856 ~ 44524381 (-)

Expression


Co-expression Network