XLOC_017066 (hsd3b2)


Basic Information

Item Value
gene id XLOC_017066
gene name hsd3b2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 1272526 ~ 1276175 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034076
CGCAGTGTCGCACATCGTCTCAGGACATCGAGGCTGTATCTGACAGAAAACAAACCTTAAAAACACCCCAGTCTGCGGATTATTCAGCATCTCCGAGGACTCGACACGGGCTTTCAACGCAGCGCTCTACATGGCTCTGTCAGGAGAGGTGTGTGTGGTGACGGGAGCCTGCGGGTTTCTGGGAGAAAAGCTGGTCCGACTGTTGCTGGAAGAGGAGAGTCTGTCTGAGATCCGGCTGCTGGACAGAAACATCCGCTCAGAGCTCATACAGACGCTTGAGGATGGCCGTGGAGAGACTAAAGTGAGTGTTATTGAGGGGGATATCCGAGACCGAGAGCTGCTGAGAAGAGCTTGTAAAGGAGCAACTCTGGTTTTCCACACTGCGTCTCTCATTGATTACAATGGAGCCGTTGAATACAGTGAATTACATGCAGTTAATGTTAAAGCTACACGGCTCCTGCTGGAGACCTGCATCCAACAAAGCGTGTCCTCCTTTATATACACCAGCAGCATTGAGGTAGCGGGTCCCAATCGCTGTGGTGAACCCATCATCAACGGCCACGAGGACACGCCTTACTACTCTTATCCTATCAGCAACTACAGCAAAACCAAGCTGGAGGCGGAGCAGATCTGCCTTCAGGCCAATGGAGAGCTGCTGCGGGACGGAGGACATCTGGCGACCTGCGCTCTCAGGCCCATGTTCATCTACGGGCCGGGTTGCAGGTTCACTTTAAACAAACTCAGAGATGCGATCCGCAGTGGAAACGTGCAGCATCGACTCTCACAGCAGAGCGCAAAAGTCAATCCAGTGTATGTAGGAAACGCCGCCCTGGCGCATCTGCAAGCAGGACGAGCGCTCAGAGACCCGGAGAAAAGAGCGGTGGTGGGGGGAAACTTCTATTACGTCTCAGACGACACGCCGCACATCAGCTATTGTGACTTAACCCATGCTCTCATGTCACCTTTAGGATTTAGCATCCAAAACAAGCCCATTCTGCCCATCTTTCTGCTGTATCTTCTGGCGTTCTTCATGGAGATCCTGCAGGCCGTGCTCCGACGCGTCCTGAGATTCACTCCACCCCTAAATAGGCAGCTAGTGACCATGGTGAACACCCCTTTTAGTTTCTCCTATCAAAAGGCTTGCAGGGAGTTCGGGTACAGTCCTCGATATGACTGGGAGGAGGCACGCAGGAGCACTACTGATTGGCTGGCGTCGGTGTTACCAGCTGAAAGACGATTGGCTAACAAGACTTGAGCGCTCGTGATGGTTATGATTAAGACTACCCTGCAAAACGTGCTCAGTTTTTCCTTGTTTCTAATTCACATCTCTATAAAATCTTCAATCGAAAAGCATATATGGGCATGTAAA
>TCONS_00034077
GCACATCGTCTCAGGACATCGAGGCTGTATCTGACAGAAAACAAACCTTAAAAACACCCCAGTCTGCGGATTATTCAGCATCTCCGAGGACTCGACACGGGCTTTCAACGCAGCGCTCTACATGGCTCTGTCAGGAGAGGTGTGTGTGGTGACGGGAGCCTGCGGGTTTCTGGGAGAAAAGCTGGTCCGACTGTTGCTGGAAGAGGAGAGTCTGTCTGAGATCCGGCTGCTGGACAGAAACATCCGCTCAGAGCTCATACAGACGCTTGAGGATGGCCGTGGAGAGACTAAAGTGAGTGTTATTGAGGGGGATATCCGAGACCGAGAGCTGCTGAGAAGAGCTTGTAAAGGAGCAACTCTGGTTTTCCACACTGCGTCTCTCATTGATTACAATGGAGCCGTTGAATACAGTGAATTACATGCAGTTAATGTTAAAGCTACACGGCTCCTGCTGGAGACCTGCATCCAACAAAGCGTGTCCTCCTTTATATACACCAGCAGCATTGAGGTAGCGGGTCCCAATCGCTGTGGTGAACCCATCATCAACGGCCACGAGGACACGCCTTACTACTCTTATCCTATCAGCAACTACAGCAAAACCAAGCTGGAGGCGGAGCAGATCTGCCTTCAGGCCAATGGAGAGCTGCTGCGGGACGGAGGACATCTGGCGACCTGCGCTCTCAGGCCCATGTTCATCTACGGGCCGGGTTGCAGGTTCACTTTAAACAAACTCAGAGATGCGATCCGCAGTGGAAACGTGCAGCATCGACTCTCACAGCAGAGCGCAAAAGTCAATCCAGTGTATGTAGGAAACGCCGCCCTGGCGCATCTGCAAGCAGGACGAGCGCTCAGAGACCCGGAGAAAAGAGCGGTGGATTTAGCATCCAAAACAAGCCCATTCTGCCCATCTTTCTGCTGTATCTTCTGGCGTTCTTCATGGAGATCCTGCAGGCCGTGCTCCGACGCGTCCTGAGATTCACTCCACCCCTAAATAGGCAGCTAGTGACCATGGTGAACACCCCTTTTAGTTTCTCCTATCAAAAGGCTTGCAGGGAGTTCGGGTACAGTCCTCGATATGACTGGGAGGAGGCACGCAGGAGCACTACTGATTGGCTGGCGTCGGTGTTACCAGCTGAAAGACGATTGGCTAACAAGACTTGAGCGCTCGTGATGGTTATGATTAAGACTACCCTGCAAAACGTGCTCAGTTTTTCCTTGTTTCTAATTCACATCTCTATAAAATCTTCAATCGAAAAGC

Function

symbol description
hsd3b2 Enables 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Acts upstream of or within embryonic morphogenesis and steroid biosynthetic process. Is expressed in brain; gonad; head kidney; and yolk syncytial layer. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2).

GO:

id name namespace
GO:0006694 steroid biosynthetic process biological_process
GO:0048598 embryonic morphogenesis biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0016491 oxidoreductase activity molecular_function
GO:0016853 isomerase activity molecular_function
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor molecular_function
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030828-2 Enables 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Acts upstream of or within embryonic morphogenesis and steroid biosynthetic process. Is expressed in brain; gonad; head kidney; and yolk syncytial layer. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2).

Ensembl:

ensembl_id ENSDARG00000019747

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034076 False 1369 mRNA 0.51 4 1272526 1276175
TCONS_00034077 True 1258 mRNA 0.52 5 1272535 1276158

Neighbor

gene id symbol gene type direction distance location
XLOC_017065 NA coding upstream 68652 1200292 ~ 1203874 (+)
XLOC_017064 lyrm2 coding upstream 73517 1196386 ~ 1199009 (+)
XLOC_017063 pnrc1 coding upstream 147131 1121458 ~ 1125395 (+)
XLOC_017062 BX537249.1 coding upstream 182923 1088658 ~ 1089603 (+)
XLOC_017061 NA coding upstream 372146 896905 ~ 900380 (+)
XLOC_017067 lrp11 coding downstream 2009 1278184 ~ 1287799 (+)
XLOC_017068 nup43 coding downstream 40320 1316495 ~ 1327859 (+)
XLOC_017069 tab2 coding downstream 53334 1329509 ~ 1350296 (+)
XLOC_017070 NA coding downstream 78488 1354663 ~ 1355683 (+)
XLOC_017071 mmachc coding downstream 109499 1385674 ~ 1393020 (+)
XLOC_017056 NA non-coding upstream 590234 681847 ~ 682292 (+)
XLOC_017074 NA non-coding downstream 387584 1663759 ~ 1725048 (+)
XLOC_017082 NA non-coding downstream 937514 2213689 ~ 2214421 (+)
XLOC_017084 BX681416.1 non-coding downstream 985758 2261933 ~ 2266612 (+)
XLOC_017085 NA non-coding downstream 1005449 2281624 ~ 2284813 (+)

Expression


Co-expression Network