XLOC_017191 (nek2)


Basic Information

Item Value
gene id XLOC_017191
gene name nek2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 13883131 ~ 13913790 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034253
TTTGAAAATCAGCTTATTTTGTCGCGTCTGTTTGTTTCTCAACTCACAAAATACGTACACGCGTTTTAACTAAGggtaaacaataaaacacactggAAGTAAAACCACAGCGTTCAAGTAGTGAGTGAGTTACGTGTGTTTGGATCTGCTGAGTTGCTGTTGAACGCGATGCCATCCAAAACTGAAGACTACGAGGTGCTGCTCACCATAGGATGTGGATCTTATGGAAAATGCCAGAAAATCAAAAGGAAATCCGATGGAAAGATTCTGGTCTGGAAGGTTCTGGACTATGGCACTATGGCCGAGGGAGAGAAACAGATGCTGGTGTCAGAAGTCAACTTGCTCCGTGAGCTGAAGCACCCAAATATCGTCCGATACCATGACCGAATTATTGACAGAACGAACACGACATTATATATAGTGATGGAATACTGTGAGGGTGGAGATCTCGCCAGCCTCATCAACAGAAGCATCAAAGACAAGCGATACCTGGAGGAAGAATTCATCCTGCGTGTGATGGCACAGTTGTCTCTGGCGTTAAAAGAATGCCATGGTAGGAGTAACGGCAGCAGTACAGTTCTGCACCGAGACCTGAAACCAGCAAACATCTTTCTGGATGCCAAACAGAATGTAAAGCTTGGCGATTTCGGTTTAGCTCGCATACTAAACCACGATACAAGCTTTGCTAAAACGTTTGTTGGAACGCCATATTACATGTCGCCAgaacaaatgaatcgcatGTCCTATAATGAGAAATCGGATATATGGTCTTTAGGGTGTTTACTCTATGAACTATGTGCTTTATCgccCCCATTTACAGCATACAACCAGACAGAGCTGGCTCGAAAAATCAGAGAAGGCAGATTTCGAAGAATCCCATACCGATACTCGGATGAGCTAAACACACTGCTTTCAAAAATGCTCAACTTAAAGgacTATCTGAGGCCCTCTGTGGAGTCCATCCTGCAGAATGGTTTGATCTCCGGTTACGTGGCCCTCGAGCAGAAGAGGCTCCAGGAGAAACAGCGGCGCAGATCAGATGAGGCAGAGCAGCCCAAACATCCAGAGTCACCACTTCTGGCAGAGCTGCGGCTTAAAGAGCAGATTCTCCGAGAGCGAGAGCAGGCCCTCAAAGAGCGAGAGCAGCGGCTAGAGCaaaGGGAACAAGAACTGTGTGTCCGAGAACAGCAAACTAATGAAAAGCTGGTCAGAGCCGAGAGCATGTTGAAGGCGTTTAATCTGATCCGACAGCAGAGGGCGCTATCTCTGCTCAGCGCCAGCGACACAGAGAATGAAGAGAACATCTCTCCAGGGAAAAAGAGGGTTCACTTTGCAGGAGACGGGAAGGAGAACGGCAGACTGATCATGAAACCTCAGGAGCACATCCTTGAGAAGAGACACCAGCTGATGAACAAGCGCATACAGACACTCGGAGAGGAGGAGAAGATGATCCACTCGCCAAAACACAGAGAAATGCAGGGAATCCGCTAGCCTTCAAAGACACTGCCACTGTGGTCAATCACGTCAAGAGGATTTCGTCTAGTTGTGTATATTAAGAGATAGATTCCTGCTTTAATTTATTTGCTGCAGCATTTGTACAGTACACTGGAGCATTTCATTTAAAGGGACAGCTAACCCCAAATTCAAAACTCTcttatcatttattcaccctccaatttttccaaaccttttcgtttctttttttattttctgatcacacaaaaatgaagatatttagaGAAATGTTGGGAATCAGTAGCCATtaactttaataaaatttgttatATCCCACTATAGATGTCTGACTATCAATTAcaaacattcttccaaatatctccttttgtgaaGAGAAAGGGAACatcttgagggtgaataaatggtaagtaatgttttattttgggtgaactgtcttttTAATGTGCATTACACTATGGATGTTTTATTGCTAGAAGCATTGTTTTTAtttggaataaataaatgaataatggttGCA
>TCONS_00034254
GCGTTTTAACTAAGggtaaacaataaaacacactggAAGTAAAACCACAGCGTTCAAGTAGTGAGTGAGTTACGTGTGTTTGGATCTGCTGAGTTGCTGTTGAACGCGATGCCATCCAAAACTGAAGACTACGAGGTGCTGCTCACCATAGGATGTGGATCTTATGGAAAATGCCAGAAAATCAAAAGGAAATCCGATGGAAAGGTTCTGGACTATGGCACTATGGCCGAGGGAGAGAAACAGATGCTGGTGTCAGAAGTCAACTTGCTCCGTGAGCTGAAGCACCCAAATATCGTCCGATACCATGACCGAATTATTGACAGAACGAACACGACATTATATATAGTGATGGAATACTGTGAGGGTGGAGATCTCGCCAGCCTCATCAACAGAAGCATCAAAGACAAGCGATACCTGGAGGAAGAATTCATCCTGCGTGTGATGGCACAGTTGTCTCTGGCGTTAAAAGAATGCCATGGTAGGAGTAACGGCAGCAGTACAGTTCTGCACCGAGACCTGAAACCAGCAAACATCTTTCTGGATGCCAAACAGAATGTAAAGCTTGGCGATTTCGGTTTAGCTCGCATACTAAACCACGATACAAGCTTTGCTAAAACGTTTGTTGGAACGCCATATTACATGTCGCCAgaacaaatgaatcgcatGTCCTATAATGAGAAATCGGATATATGGTCTTTAGGGTGTTTACTCTATGAACTATGTGCTTTATCgccCCCATTTACAGCATACAACCAGACAGAGCTGGCTCGAAAAATCAGAGAAGGCAGATTTCGAAGAATCCCATACCGATACTCGGATGAGCTAAACACACTGCTTTCAAAAATGCTCAACTTAAAG
>TCONS_00034255
TGTGTTTGGATCTGCTGAGTTGCTGTTGAACGCGATGCCATCCAAAACTGAAGACTACGAGGTGCTGCTCACCATAGGATGTGGATCTTATGGAAAATGCCAGAAAATCAAAAGGAAATCCGATGGAAAGATTCTGGTCTGGAAGGTTCTGGACTATGGCACTATGGCCGAGGGAGAGAAACAGATGCTGGTGTCAGAAGTCAACTTGCTCCGTGAGCTGAAGCACCCAAATATCGTCCGATACCATGACCGAATTATTGACAGAACGAACACGACATTATATATAGTGATGGAATACTGTGAGGGTGGAGATCTCGCCAGCCTCATCAACAGAAGCATCAAAGACAAGCGATACCTGGAGGAAGAATTCATCCTGCGTGTGATGGCACAGTTGTCTCTGGCGTTAAAAGAATGCCATGGTAGGAGTAACGGCAGCAGTACAGTTCTGCACCGAGACCTGAAACCAGCAAACATCTTTCTGGATGCCAAACAGAATGTAAAGCTTGGCGATTTCGGTTTAGCTCGCATACTAAACCACGATACAAGCTTTGCTAAAACGTTTGTTGGAACGCCATATTACATGTCGCCAgaacaaatgaatcgcatGTCCTATAATGAGAAATCGGATATATGGTCTTTAGGGTGTTTACTCTATGAACTATGTGCTTTATCgccCCCATTTACAGCATACAACCAGACAGAGCTGGCTCGAAAAATCAGAGAAGGCAGATTTCGAAGAATCCCATACCGATACTCGGATGAGCTAAACACACTGCTTTCAAAAATGCTCAACTTAAAGgacTATCTGAGGCCCTCTGTGGAGTCCATCCTGCAGAATGGTTTGATCTCCGGTTACGTGGCCCTCGAGCAGAAGAGGCTCCAGGAGAAACAGCGGCGCAGATCAGATGAGGCAGAGCAGCCCAAACATCCAGAGTCACCACTTCTGGCAGAGCTGCGGCTTAAAGAGCAGATTCTCCGAGAGCGAGAGCAGGCCCTCAAAGAGCGAGAGCAGCGGCTAGAGCaaaGGGAACAAGAACTGTGTGTCCGAGAACAGCAAACTAATGAAAAGCTGGTCAGAGCCGAGAGCATGTTGAAGGCGTTTAATCTGATCCGACAGCAGAGGGCGCTATCTCTGCTCAGCGCCAGCGACACAGAGAATGAAGAGAACATCTCTCCAGGGAAAAAGAGGGTTCACTTTGCAGGAGACGGGAAGGAGAACGGCAGACTGATCATGAAACCTCAGGAGCACATCCTTGAGAAGAGACACCAGCTGATGAACAAGCGCATACAGACACTCGGAGAGGAGGAGAAGATGATCCACTCGCCAAAACACAGAGAAATGCAGGGAATCCGCTAGCCTTCAAAGACACTGCCACTGTGGTCAATCACGTCAAGAGGATTTCGTCTAGTTGTGTATATTAAGAGATAGATTCCTGCTTTAATTTATTTGCTGCAGCATTTGTACAGTACACTGGAGCATTTCATTTAAAGGGACAGCTAACCCCAAATTCAAAACTCTcttatcatttattcaccctccaatttttccaaaccttttcgtttctttttttattttctgatcacacaaaaatgaagatatttagaGAAATGTTGGGAATCAGTAGCCATtaactttaataaaatttgttatATCCCACTATAGATGTCTGACTATCAATTAcaaacattcttccaaatatctccttttgtgaaGAGAAAGGGAACatcttgagggtgaataaatggtaagtaatgttttattttgggtgaactgtcttttTAATGTGCATTACACTATGGATGTTTTATTGCTAGAAGCATTGTTTTTAtttggaataaataaatgaataatggttGCACTTATATGTATTTGCTTCTGTTGTGGGTCACTGACGCAAGCTTTAGCTGTAAGGGACATGCTGTGTTTGTACGCGGAGTTTTGCGCTTTTCTAGAAAGCTCTGATTTTCCTCGATCCCGAGCGCTCAACCAATCACATGAGTGTGGGCGTGGCTAGCCGCTGAGCGTGTTCCGTGTGGAAAGTTCGCCGGTCCGGGTGCAAAGTTTCAGCCGTCTGCAGACGAGCGGCAGAATACGGGCTGTATAACCGGACCGAACCCGCTCCTCGGCGCTCATTACACGCGGATAAGCGCAGCGCTTACAGCCTGTCCATCGGGGAACGAGCTCAGTGATGGGATATTAACCCGAAGGGGGTCGCTTCGATTTAAAGCTTTGTTTCTGTCTGTGCTCCGCCCGCGGTGTGATCATGGCCTGCGCGCCGAACCGGGTTCGCCTGCTCTGCATGCTGTCGCTCACCTTCGGCTTCTTCATCGTGGAGGTAGTGGTCAGCCGGATCACCTCCTCTCTGGCGATGCTCTCGGACTCATTCCACATGCTGTCGGACGTGATCGCGCTGGTCGTGGCTCTGGTCGCGGTGCGCTTTGCCGAGCAGACCCAGTCCACCAACAAGAACACCTTCGGCTGGATCCGGGCCGAGGTGATGGGCGCGCTGGTCAACGCCGTGTTCCTGACCGCGCTCTGCTTCACCATCATTCTCGAGGCCATCGAACGCTTCACTGAGCCGCACGAGATCGAGCAGCCCTGGGTTGTGATCGGGGTGGGGGCTCTGGGGTTGCTGGTCAACCTGCTCGGGCTCTGCCTCTTTCACGGGCACGCCGGCGGCGGGGGACACGGGCATTCGCACGGCGGACACGGACACAGCCACGGCGGAGCCAAAAAACACAAGAACGGGAAGGTCCGCCGGAGCGAGACGCTGGAGGACAGTCGATCCGCCGGAGAGGAAACCAACAACCTGGTCGCGAATCACAACAGCCCGAATGGCGTTAATGCGGAGCGGAAGGCTGCCG
>TCONS_00034256
TCTGCAGACGAGCGGCAGAATACGGGCTGTATAACCGGACCGAACCCGCTCCTCGGCGCTCATTACACGCGGATAAGCGCAGCGCTTACAGCCTGTCCATCGGGGAACGAGCTCAGTGATGGGATATTAACCCGAAGGGGGTCGCTTCGATTTAAAGCTTTGTTTCTGTCTGTGCTCCGCCCGCGGTGTGATCATGGCCTGCGCGCCGAACCGGGTTCGCCTGCTCTGCATGCTGTCGCTCACCTTCGGCTTCTTCATCGTGGAGGTAGTGGTCAGCCGGATCACCTCCTCTCTGGCGATGCTCTCGGACTCATTCCACATGCTGTCGGACGTGATCGCGCTGGTCGTGGCTCTGGTCGCGGTGCGCTTTGCCGAGCAGACCCAGTCCACCAACAAGAACACCTTCGGCTGGATCCGGGCCGAGGTGATGGGCGCGCTGGTCAACGCCGTGTTCCTGACCGCGCTCTGCTTCACCATCATTCTCGAGGCCATCGAACGCTTCACTGAGCCGCACGAGATCGAGCAGCCCTGGGTTGTGATCGGGGTGGGGGCTCTGGGGTTGCTGGTCAACCTGCTCGGGCTCTGCCTCTTTCACGGGCACGCCGGCGGCGGGGGACACGGGCATTCGCACGGCGGACACGGACACAGCCACGGCGGAGCCAAAAAACACAAGAACGGGAAGGTCCGCCGGAGCGAGACGCTGGAGGACAGTCGATCCGCCGGAGAGGAAACCAACAACCTGGTCGCGAATCACAACAGCCCGAATGGCGTTAATGCGGAGCGGAAGGCTGCCGATATGTGTCACAGTGACAGCCTGGATCTGCAGATTAATGGCAGTGCTCCATATGACGAGCTGGAGAACGGACACGATGCTGCCTCCCAGCTCAACATGCGGGGTGTTTTCCTGCATGTCCTGGGTGATGCCCTCGGCTCTGTTATCGTGGTGATCAACGCCATCATTTTTGTGTTCGTGTGGAAGCCCTGTGAACCTGGCACCATCTGCGAGAACCCTTGTTCGGGTCAACATTGCGCAGACCATGCACTTAACATCAGCAGTCCATTAACTAACGGCACTTTGATCAAAGCAGGACCGTGCTGGGTGCTTTATCTGGACCCCACACTCTGCATCATCATGGTCTGCATCCTTCTCTACACCACCTACCCCCTGCTAAAGGAGTCCGCTCTTATCCTGCTCCAAACCGTACCCAAGCAAATCGACATGCACCAGCTGAACGCTCGCCTGCGGGATCTGGAGGGCGTTCTGGCCGTGCACGAGCTGCACATCTGGCAGCTGGCGGGCAGTCGCATTATCGCAACAGCGCACATTAAATGCCACGACCCCACATCCTACATGGATGTAGCCAAGCGCATCAAGGACTTTTTCCATGATGAGGGCATCCACGCGACAACTATTCAACCGGAATTCGTAACGGTGAATTCAGAGTCCCGCGCTTCGCTCTGTGAGCTCTCCTGCCGAACGCAGTGTGCACCAAAGCTCTGTTGTGGGGCTGTTGATACCGCAAAACCTCTTGAAGGTTCTTTAGAGTCAAAGAAGTCATGCGAATCCAAAACCCCAACATTACCTAGCGCTTCTGTGACGTCTCTGGAAATCATCAGCGAGTCCGTGGAGGACACGAGCCGACCAGAATCTGTCGTGATCATCACTAGGGAGGTGGAGTCATCGCTGTGAGTGATCTCTGTATTGGTGATCTAGTGTATTGGATCAGCTGACTGATTTCTAACGTGCTGTGAGAAGAACTGAGcccaaacacattcacacacaccacACAGCCGTGTATCTCAGACATCACACCAACTTTCCGACAATATAAAGAGCCTGCTCTGCATGTGTGTTTACCACGTCGTCTGATTGGTGTGTCCGTGCCAAAGCTTCTCTTCATACAGGACGTCAACACTCATGGATGTAATGCAATTTTAACGTTCGGCTGCTGGACCAAGTAAAAACGTCGGGACCATTTGTATTTCTACCCATCACTTGCCCGTTTTCTTCTTCACACCTTACATATTTAGCTTTTCAATTTTTGTGAGAGATgtaataatttatgtatttaagtTATtggtaattattattttgtttcctaaagagctttttgtaatatttagatttggttatatatatatctatatatatatttggagaGGTAAAAGAAATGATTTGCTTCTTTCGAAACAAATGATCTATGCTTTAGAGTATTTTTaaatctgatgttttttttttaaagatcgcTGTGTAATCGTTTAAAGACACATCAGAAGATGCGTCGACAGTATTTCACCAAGCCTATAATTGAAACTGCTGTATTATAGCACTGAATATGTTCAGTGTAGGAACTAGACAACCTTCTCTTATTGGTTTTGATACAAGCTGATGCCTTCTTTGTTCTGTCGTTCTGTCAATCAAAACAAGAGgtttaaatgctgtaaaataaactgtGGAACTGGCTGATGTTTAGTCCGTGCTGACGTAAACCTGAAGGGACCTTCATATATTTGTGGAAAACGCTCATTTGGCAACTGTGTGTGTGACCAAATATAATTGTGGTTATAAGGAAATCTTTGAGAAAACCAAGCAACATTTGTAAACCAAAAGAAAAGGGAGTTGTGTTCTGGACTATGCAGGGAGTAGGCACGTGGGTTTGGCTTTGAACACATCATTTGAGGTGTTGCGAAATCCTCTCCGTGGCCTATATTGGGGAAAGAAACAGAATATAAACTCTTCAGAACACTATTTATTTCTTCAAGTATTTAGCATTTGGTGAAATTatgcaatttattaaaaacacaaatgtataGCCTTTATAACTAGTCAACTTTATTAGAAATCTGTAGAGGAACGAGTTCACTTTATAAACGTGCAGATGACGTGTTTGTATCACTGAGGATTTTAAAAGTACCCTGCCAGCTGAAATGTTTTTTGATATGTTATTGTCAAACGTGTCATTGTGAATTAAACATGCTTGTTTGGTACTGTTCAA

Function

symbol description
nek2 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within retinal rod cell development. Predicted to be active in centrosome; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 67. Orthologous to human NEK2 (NIMA related kinase 2).

GO:

id name namespace
GO:0046548 retinal rod cell development biological_process
GO:0006468 protein phosphorylation biological_process
GO:0007059 chromosome segregation biological_process
GO:0016310 phosphorylation biological_process
GO:0005813 centrosome cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG:

id description
ko01001 Protein kinases
ko01009 Protein phosphatases and associated proteins
ko03036 Chromosome and associated proteins

ZFIN:

id description
ZDB-GENE-040426-1840 Predicted to enable calcium channel inhibitor activity and zinc ion transmembrane transporter activity. Acts upstream of or within response to zinc ion. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Predicted to be integral component of membrane. Is expressed in central nervous system; hatching gland; and yolk syncytial layer. Orthologous to human SLC30A1 (solute carrier family 30 member 1).
ZDB-GENE-040426-752 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within retinal rod cell development. Predicted to be active in centrosome; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 67. Orthologous to human NEK2 (NIMA related kinase 2).

Ensembl:

ensembl_id ENSDARG00000005463 ENSDARG00000005619

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034253 False 1993 mRNA 0.44 10 13883131 13893910
TCONS_00034254 False 858 mRNA 0.44 6 13883191 13887133
TCONS_00034255 False 2865 mRNA 0.50 9 13883353 13894916
TCONS_00034256 True 2996 mRNA 0.48 2 13894123 13913790

Neighbor

gene id symbol gene type direction distance location
XLOC_017190 lpgat1 coding upstream 8791 13781779 ~ 13874340 (+)
XLOC_017189 NA coding upstream 218080 13640945 ~ 13665051 (+)
XLOC_017188 sytl3 coding upstream 317411 13533544 ~ 13565720 (+)
XLOC_017187 enpp1 coding upstream 362121 13403281 ~ 13521010 (+)
XLOC_017186 ppp2r5a coding upstream 571213 13175379 ~ 13311918 (+)
XLOC_017192 si:dkey-249p7.4 coding downstream 42316 13956106 ~ 13959214 (+)
XLOC_017193 rd3 coding downstream 55624 13969414 ~ 13997835 (+)
XLOC_017194 NA coding downstream 101022 14014812 ~ 14041218 (+)
XLOC_017195 kcns3b coding downstream 200468 14114258 ~ 14118296 (+)
XLOC_017196 NA coding downstream 230286 14144076 ~ 14147484 (+)
XLOC_017184 BX547930.2 non-coding upstream 879948 13001068 ~ 13003183 (+)
XLOC_017183 BX547930.3 non-coding upstream 908410 12968914 ~ 12974721 (+)
XLOC_017182 BX547930.1 non-coding upstream 974006 12907233 ~ 12909125 (+)
XLOC_017179 NA non-coding upstream 1200991 12642740 ~ 12682140 (+)
XLOC_017198 NA non-coding downstream 573967 14487757 ~ 14623918 (+)
XLOC_017199 BX901920.1 non-coding downstream 743351 14657141 ~ 14661432 (+)
XLOC_017202 mir199-3a non-coding downstream 961670 14875460 ~ 14875546 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000051_06033224_06041180 SLC30A1A coding CI01000051 null 6033042 ~ 6041180 (-)
bowfin (Amia calva) AMCG00004276 slc30a1a,slc30a1 coding CM030121.1 CM030121.1 40906392 ~ 40921474 (+)