XLOC_017302 (nek1)


Basic Information

Item Value
gene id XLOC_017302
gene name nek1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 23670494 ~ 23714017 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034445
ATGGATAAATATGAGAGGTTAAAGAAGATTGGGGAGGGATCCTTTGGGAAAGCCATCTTGGTCAAGTCAAGGACAGATGGCCGACAATATGTTATCAAGGAGATTGGTATCTCCAGGatgtCGAACAAGGAACGACAGGAATCACGTAAAGAGGTGGCAGTTCTGGCTAACATGAGCCATCCAAACATTGTCCAATACAAGGAATCCTTTGAAGAGAGTGGTTGTTTGTACATTGTAATGGACTACTGTGAGGGAGGAGACCTGTTTAAGAAGATCAATAATCAAAGAGGATCTCTTTTCCCAGAGGAACAGATTCTTGACTGGTTTGTGCAAATCTGTCTGGCTCTTAAACATGTACACGACCGCAAAATCCTACATAGGGACATCAAATCACAGAATATTTTTCTGACCAAAGATGGTACTGTGCAGCTTGGAGACTTTGGAATCGCTAGAGTTTTGAACAGcaCCGTGGAGTTGGCAAGGACATGTATCGGCACTCCTTATTACCTGTCGCCAGAGATATGTGAAAATAAACCATACAACAACAAGAGTGATATCTGGGCCCTGGGATGTGTCCTGTATGAAATGTGCACGCTTAAGCATGCATTTGAAGCAGGAAACATGAAGAACCTGGTGCTGAAAATCATCCGTGGTTCATACCCGCCTGTTTCCATCCATTACTCCCCAGATTTGCGCTCTCTCCTGGCCCAGCTCTTCAAGCGTAACCCCCGGGAGAGACCCTCCGTCTCGACCATTTTGGACAAGCCTTTTCTTGCTCGCAGAATTCACAAGTTTCTCAGCCCTCAGGTGACATATACACACGAACAGACTCGATTAGCAGTGTGA
>TCONS_00034446
TGATATCTGGGCCCTGGGATGTGTCCTGTATGAAATGTGCACGCTTAAGCATGCATTTGAAGCAGGAAACATGAAGAACCTGGTGCTGAAAATCATCCGTGGTTCATACCCGCCTGTTTCCATCCATTACTCCCCAGATTTGCGCTCTCTCCTGGCCCAGCTCTTCAAGCGTAACCCCCGGGAGAGACCCTCCGTCTCGACCATTTTGGACAAGCCTTTTCTTGCTCGCAGAATTCACAAGTTTCTCAGCCCTCAGCTTATTGCTCAGGAATTCAGCCATTCAATTCACCTTCAGCCCAAAATGAGTGTGGCCCATGCAGCACCAGCCAAACGTCCAGCCCCAGGCCCTATCCCAATCACCTCAGCTCAGAAAATCACCAAACCAGCAGCCAAATACGGAGTGCCTTTAACAGTGCGGAGACCATCTGAAGTCGCCAGGAAGGTCCCAGATGCAGCAAAGAAACCAGTTAAACTTAAGCAGGCTCCCCCTCCTGCAGCGGTTCAGAGGAGAGTGAGTCGAGTGGAGGAGGAGAGGAGAAAGCATGAGGAAGGAGTGAGGAAGAAGCGGATGGAGATGatggaaagagagagaaaacaaaGAGAACAGATGTTGTTACTGAAGGCTGCTCAGATGAAGAGATTTGAGAGAGAAAAGCTGAACCGAATCAACCGAGCTCGAGAGCAGGGCTGGAGACACGTGCTGAGTTCTAGTGGAGGAAGCAGTCCTGAGCGGAAGTTTTATGGAGGTGGCGGCGGCAATGGAGCTCCCCATTCCCCAGGAATATCTCCCTTTCCTGTGCCTGGACCCTCCCCTGTTCCTTCTTCAGCTTTAGCTCCAAGCAGAGCGCCATATGACCGCATCCACCCTTCAGCTGAAAAATTAACCAAACCTACACCTAAAGATGGTGCTGGTGAAGGAGCCGTGCATGCAGGGGACAATGGCAGGACTTCTTCAGACTCAGGGACTCTAAATGGTCATGCCTGCATTCCTGTTAAGAATGGCGTCAGGAAAGAACAACGTAAAACAAGTCTCCAAAATGAGCAGATTTCAAAGATCGACTATGCCAATAGGTTTCGAGGTCAGCTGGCAGTAGAGAAATCCAAGCAGGTGGAGGAGTTTCTACAGCGGAAAAGAGAAGCCATGCTGAATAAAGTTCGTGCAGAAGGACAGCTGGAGTATTTGACCAGATTACGACAGATCAGACTACAGAACTTTAATGAACGTCAGCAGATTAAAGCTCGGCTCAGAGGGGAGAAGTATGACAGTGATGGCTCAGACAGTCAGGAGTCATGTGAAGAGGCAGTGCTCAGGATGAAGAAGATTGAGGCTTTGAAGGCCCAGTCAAAGGCTCGTGCTGCTGTACTGAAAGAGCAGCTggaaaagaagagaagagaagcgTATGAAAGAGAGAAGAAAGCATGGGAGGATCATCTTGTCGCTCGAGGAGTAAAAGTTGCAGTTGGGCCTGTGGGTGGGACTCCCTCTCCTGCAGCCCCTCCAACTCCACCATCTGACCCCACCCCTCAGGAAGCTCCTTCTAAAGCCACACCCTCCTCTAGACCCAGCACTCCAGCCATCTCTATGACTGCTGCACTGAAGGATGTGGGCGCGATTTCATCAGGGCAGAGTTCTCCTATGAAAGAGGACTCCCTTAAAGTTGAATCATCAGATGTACAGAGTGACAAGAAGGAGATTCTTCGCAGACTTAATCAGAAGGTTCAGACCACTGAGGAAGTTTCTGTAAAAGAGCCCACACCCTCCAGCAATCAACCATGTCCTGATCCTCAGCCAGTCCAACCCTCCATCACAGAGGAAAGGCCTTCCACAGCTGCAGATAGGAAGAAGTGGGAAGCCGTAGCTCCACCCATACTGTCTGTTGCTGAACAGACTCTCGAGGAAACCTGTGCTACTCTGGCAGTGTCTCAGGTGGCATCACCAGAAACGAATACTCCCTCGTGTGGAGACAGGAAGAAATGGCAGACAGATGGTGTTCCTCTTCTGTCTGTGGCTCAGCAGACACTGGAAGAAACCAGCTTTAGAACAGCTGGTCAATTAACAGAAAAAACAGTAGGTGAAGTCATTTGCATGGATGCCTGGCAGGGGGAGGGGCTAAGGAAGGCTTGGGGGCAGAGTCCAGATTCAGAGGTTTTGAAGGTGTTGGAAGAGGCAGAACTTCAGTCATTTACTCAGAGACTAGATCCTGCCAGCACGTGTGACCAAACACTGACTGAAAGCCTTAATCCCATTGAGGAATCGGATGCCACTAATGAAGCCAAGCAAGTGCCTCCTCCTGAACCGTGCCAGCCTGCCACTGACCATGACAAACAAGAAGTGACATGTCAAGAGACAGTGCCAATCATAGAAGAGGTTAAAAGTCAGGAACTTATCCAAACAACAGCAGAGGGGACAGAAAAATCTCATTCTGCAGAAAGTGACATAGAGGTGGTGGATGATATGGAGTCAGTTGTTCTGGATGATGTACCACAGAAAACCGCAGAGCCGCCCCCTGCAGAAGTAATTCAGGCGTGGACTAAAGACACTCCAGAGTCTCTGCCAGCAGAGGGCAGAGTAATACAAGCAGAATGCACAGAGGTACCTCAGAGAGAAGAGAAACATCCTGAACCTCCAGCAGATGAGTCTTTGTTTGTGAAGTTAAGCAGTAGTCCAGCTCACAGACGCACAGTAGCGTTGGCCATGCTGTCTGCTCAATCCTCATTGGAAGACTCTTCCTCTGCTGCCTCACGTTCTCGATCAGTGTCTCCACTGCGCTCCCACCGCCATGAAGATGCACTGCTCATCGGCCTCTCCACTGGCCTCTTCGATGCAAATAACCCAAAGATGCTAAGGACGTGCTCCTTACCAGACCTCAGTAAGGTGTTTAGTGATGCTACAGGACCTGAAGGTGCAGCCGCTCCTGACAGCAACCTAGAAATTGAAGATCTGGAAGATAAAGCAGATGAGCAGTCTGAACCTGAGGATGTGTATGAGGATGACGATTTAAGAGAGCTCAGAGCATCTATGGAGAGGCTTCTTCAGGAGCAGCacagtgaagatgatgatgatgaagaagaggaTGAGGGTGGTGGATCTAATGGCAGCCCGGCCGATGAAGAGCCAGCTGGTCTTAATGGGTTAGCTAGTGCTGGTGATGACAAACGCAGCCCAGAGGAAGAGACTTTTAATGGAATGGCTGAAGATGATGAGGATGTTAGCCATGGTGAAGAAGAACCAGGAGGCCCAGTCACAAATGGAATGGAATTTGAAGATGATGAAGAGCAGAACAGCAGTGAAGCACAGCTCAATGAGGAGTGGCAGTCAGATGGCAGCGAGGAGGAGGACGACGAAGAGCTGGAACAGCAGGACAGCATCTTCAGTCGTCTGGAGGAGCTGCGGCTTCATCTAGAGCAGGCCATGGGCTTTGAGAACTTCATCCAGGCCTACAACAAGATCAAGgCTATTCATGAGGATGAGGATGAAAACATTGCAATGGGCTCCAGCATGGTGCAAAACATTTTGGGAACTGAGCACCAGCACTTGTATCCTAAAATCCTCCATTTGGTGATGGCAGATGGAGCTTACCAGGAAGataaTGATGAATAGAAGTTATTCATCCGTGCTGTTGGCAGCCTTGGACAATCTGCTGGCAGGCTGAAGTGTTCCCATGATGCACTCTGACAGGCCGAGGAGGTGCATGTGGGGAAAGGGGAGGGAAAAGGGGGAAATGGGCCACTCAAGCATGGGCAGTTTAGAGTCCACGCTTGACCGTAGTTCTACTTCCATATCCCAAGCAACCGAAGCACTGCTCTGTAAATTTTGTGCATATAAATGTGCTGTGGATAATAATATTTAACCAAAGCGTAGCCGAGTGTTAGCAGGCGAGAGGTAGGACGTCCCGGACGGAGATGTACATGCGTGTCTTCCTATAGCTGATgacagactgtgtgtgtgaaaatgctgCTCAGGCTGTATTCACAACAGCTGAAGCCCTGGAAACTGCTTTTTAGGGCTCTAGACTGGCCAGGGAGGTCTAGTTCAGGGGGACGGAGGTCAATTATCTGCCCAATATCAGGTGCTCGCACACAACGGGCAGCCGGTTTTTAACCAGCTGTCTACCTCAGACAACAGACAAGTCTTAACTGCTAGTCTAAAAATACCAGTCTTCTCAAATCTTTTCTGAAAGCTCTTTTTCTACTTTTTACACATTGTTTATTTGATATCCTCAGAAATTATTTTGCCTTATTCAAGATTTCTTCCCGATTCGATGAGGCTTAATGCATTAGGTCCAGATATGGCTTTTATTTAGGGAGCTTGAGTAGATTTACTATGCATATATCCAGTGTTTTAACACACTTGTTGGCTTTagtaaagggattgttcacccaaataataataataatcatcatctaaTATTGTTtactggaattattattattattattgtgaaagtagatattttgaagaatgtttacaATTTTTGCACATACAATGATAAGAATAAGGATTAAAACAACACTGGTCCCCATTTACGTTTATTGTatggacaaaaaaacaaacataaatagcgatttatttagtttttttggatGAGCTATCCCTTTAGAAGCGTTTATAAACTGCGCATGTTGTATGCAGACTCACCTCTAACGGGACGAATTGCTCATTTTAGCTGGCAGAATGTGCTACTTGAAAGTGTACAGAATTGTAAAAATAACTTGCAAGCATTATCGTTTGGTTGCATGTCAGAATATGTATATCTTTGTACCGAGAAATaaaacttcttctttttttcttaaa
>TCONS_00034447
GATAGAGAGATGATATGTATCTGTGCATTTCACAGGAGTATTTGACCAGATTACGACAGATCAGACTACAGAACTTTAATGAACGTCAGCAGATTAAAGCTCGGCTCAGAGGGGAGAAGTATGACAGTGATGGCTCAGACAGTCAGGAGTCATGTGAAGAGGCAGTGCTCAGGATGAAGAAGATTGAGGCTTTGAAGGCCCAGTCAAAGGCTCGTGCTGCTGTACTGAAAGAGCAGCTggaaaagaagagaagagaagcgTATGAAAGAGAGAAGAAAGCATGGGAGGATCA

Function

symbol description
nek1 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within cilium assembly and cranial skeletal system development. Predicted to be active in centrosome; cytoplasm; and nucleus. Is expressed in forebrain; head; midbrain; and retina. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; asphyxiating thoracic dystrophy; and short-rib thoracic dysplasia 6 with or without polydactyly. Orthologous to human NEK1 (NIMA related kinase 1).

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0007059 chromosome segregation biological_process
GO:1904888 cranial skeletal system development biological_process
GO:0060271 cilium assembly biological_process
GO:0016310 phosphorylation biological_process
GO:0005813 centrosome cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040730-1 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within cilium assembly and cranial skeletal system development. Predicted to be active in centrosome; cytoplasm; and nucleus. Is expressed in forebrain; head; midbrain; and retina. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; asphyxiating thoracic dystrophy; and short-rib thoracic dysplasia 6 with or without polydactyly. Orthologous to human NEK1 (NIMA related kinase 1).

Ensembl:

ensembl_id ENSDARG00000022350

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034445 False 846 mRNA 0.45 8 23670494 23677379
TCONS_00034446 False 4795 mRNA 0.47 28 23676649 23714017
TCONS_00034447 True 292 lncRNA 0.46 3 23687048 23688804

Neighbor

gene id symbol gene type direction distance location
XLOC_017300 si:ch211-191d2.2 coding upstream 2781 23657860 ~ 23667713 (+)
XLOC_017301 NA coding upstream 7947 23662006 ~ 23662547 (+)
XLOC_017299 palld coding upstream 21466 23498255 ~ 23649028 (+)
XLOC_017298 si:dkey-90m5.4 coding upstream 225841 23440632 ~ 23444653 (+)
XLOC_017297 fryl coding upstream 248149 23315242 ~ 23422345 (+)
XLOC_017303 sh3rf1 coding downstream 28557 23742574 ~ 23836967 (+)
XLOC_017304 BX255904.1 coding downstream 52936 23766953 ~ 23767069 (+)
XLOC_017305 ginm1 coding downstream 141008 23855025 ~ 23860808 (+)
XLOC_017306 NA coding downstream 196405 23910422 ~ 23912606 (+)
XLOC_017307 casp8ap2 coding downstream 232987 23947004 ~ 23956014 (+)
XLOC_017296 BX323889.2 non-coding upstream 401807 23254477 ~ 23268687 (+)
XLOC_017294 BX323889.1 non-coding upstream 437690 23232690 ~ 23232804 (+)
XLOC_017290 CU693368.5 non-coding upstream 594177 23076201 ~ 23076317 (+)
XLOC_017289 NA non-coding upstream 638758 23026257 ~ 23031736 (+)
XLOC_017309 BX119992.1 non-coding downstream 418056 24132073 ~ 24138562 (+)
XLOC_017310 BX901952.1 non-coding downstream 651930 24365947 ~ 24373933 (+)
XLOC_017311 NA non-coding downstream 675605 24389622 ~ 24704953 (+)

Expression


Co-expression Network