XLOC_017903 (dhcr24)


Basic Information

Item Value
gene id XLOC_017903
gene name dhcr24
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 7149100 ~ 7176810 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035327
AAATCGTACGCGTGCAAGCGGGGAAACTGTGCTCAAGGGAAACGAGGAGACGCATGAAATAACTGTTTATTAAGCTTCATGCGTTTTTAAAGTGCTTGCAAATTCAAAACGTCGTCGGCATGGATCCGTTATTGTATTTGGGAGGGTTAGCTGTGTTGTTTTTGATATGGATCAAAGTGAAAGGCTTGGAGTACGTGATTATACACCAGAGATGGATCTTCGTGTGCCTGTTTCTCCTGCCCTTGTCCGTCGTGTTTGATGTGTACTATCACCTGCGCGCCTGGATCATCTTCAAGATGTGCTCCGCGCCCAAACAGCACGACCAGCGGGTCAGAGACATTCAGAGACAGGTGCGAGAATGGAGGAAAGATGGAGGGAAGAAATATATGTGCACGGGACGTCCGGGATGGCTGACTGTGTCCCTCAGAGTGGGAAAATACAAGAAAACTCACAAGAACATCATGATTAACATGATGGACATCCTGGAGGTTGACACAAAACAAAAGGTAGTGCGTGTGGAGCCTTTAGCTAACATGGGTCAGGTGACTGCTCTGCTCAACTCTATTGGCTGGACACTGCCGGTGCTGCCAGAACTCGATGACCTCACTGTTGGCGGGCTGGTGATGGGAACAGGCATTGAGTCTTCATCTCACATCTACGGCCTGTTTCAGCACATCTGTGTGGCCTTTGAGCTGGTGTTGGCTGACGGCAGTCTGGTCCGCTGCACTGAGAAAGAAAACTCTGACCTGTTTTATGCCGTTCCCTGGTCCTGCGGGACTCTGGGGTTTCTGGTTGCGGCAGAGATCCGGATAATTCCAGCTCAGAAATGGGTGAAGCTGCACTATGAACCTGTTCGCGGCTTGGATGCAATTTGCAAAAAGTTTGCTGAGGAATCTGCCAATAAGGAGAACCAGTTTGTTGAGGGACTTCAGTACTCTCGGGACGAGGCTGTGATTATGACCGGCGTCATGACGGATCATGCAGAGCCTGACAAGACTAACTGTATAGGTTATTATTACAAGCCGTGGTTCTTTCGGCATGTGGAGAGTTTCCTGAAGCAGAACCGCGTTGCAGTGGAGTACATTCCTCTCCGCCACTATTACCACAGACACACCCGCAGCATCTTCTGGGAGTTACAAGACATTATTCCATTTGGGAATAACCCGTTGTTCCGGTATGTGTTTGGCTGGATGGTTCCTCCAAAGATCTCTCTGCTAAAGCTTACTCAGGGAGAGACCATCCGCAAACTGTACGAGCAGCACCATGTGGTGCAGGACATGCTGGTCCCCATGAAGGACATCAAGGCTGCCATCCAGCGTTTCCATGAGGACATTCATgtgTATCCTCTGTGGCTGTGTCCATTCCTTTTGCCCAACCAGCCAGGAATGGTGCATCCTAAAGGAGATGAAGATGAACTGTATGTTGATATCGGAGCATATGGAGAACCTAAGGTCAAACACTTTGAGGCCACATCATCCACACGGCAGCTGGAGAAGTTTGTCAGAGACGTTCACGGATTCCAGATGTTGTATGCTGATGTATACATGGAACGCAAGGAATTCTGGGAGATGTTTGACGGCACTTTGTATCACAAACTCAGAGAGGAGCTCGGCTGTAAAGATGCATTCCCTGAAGTCTTTGACAAAATCTGCAAGTCTGCAAGACATTGAATCCAAATGAACCTGAGACATggccaaaacaataaacaaaacatatgaTATATTGCTGACAACATTGGGGTCAGACACACTTAAAACATAGATACTCTTATTCACAATGGAGCACCAGCAAATGTgacaatattttataaaaataatttttattcctt
>TCONS_00035328
AATCGTACGCGTGCAAGCGGGGAAACTGTGCTCAAGGGAAACGAGGAGACGCATGAAATAACTGTTTATTAAGCTTCATGCGTTTTTAAAGTGCTTGCAAATTCAAAACGTCGTCGGCATGGATCCGTTATTGTATTTGGGAGGGTTAGCTGTGTTGTTTTTGATATGGATCAAAGTGAAAGGCTTGGAGTACGTGATTATACACCAGAGATGGATCTTCGTGTGCCTGTTTCTCCTGCCCTTGTCCGTCGTGTTTGATGTGTACTATCACCTGCGCGCCTGGATCATCTTCAAGATGTGCTCCGCGCCCAAACAGCACGACCAGCGGGTCAGAGACATTCAGAGACAGGTGCGAGAATGGAGGAAAGATGGAGGGAAGAAATATATGTGCACGGGACGTCCGGGATGGCTGACTGTGTCCCTCAGAGTGGGAAAATACAAGAAAACTCACAAGAACATCATGATTAACATGATGGACATCCTGGAGGTTGACACAAAACAAAAGGTAGTGCGTGTGGAGCCTTTAGCTAACATGGGTCAGGTGACTGCTCTGCTCAACTCTATTGGCTGGACACTGCCGGTGCTGCCAGAACTCGATGACCTCACTGTTGGCGGGCTGGTGATGGGAACAGGCATTGAGTCTTCATCTCACATCTACGGCCTGTTTCAGCACATCTGTGTGGCCTTTGAGCTGGTGTTGGCTGACGGCAGTCTGGTCCGCTGCACTGAGAAAGAAAACTCTGACCTGTTTTATGCCGTTCCCTGGTCCTGCGGGACTCTGGGGTTTCTGGTTGCGGCAGAGATCCGGATAATTCCAGCTCAGAAATGGGTGAAGCTGCACTATGAACCTGTTCGCGGCTTGGATGCAATTTGCAAAAAGTTTGCTGAGGAATCTGCCAATAAGGAGAACCAGTTTGTTGAGGGACTTCAGTACTCTCGGGACGAGGCTGTGATTATGACCGGCGTCATGACGGATCATGCAGAGCCTGACAAGACTAACTGTATAGGTTATTATTACAAGCCGTGGTTCTTTCGGCATGTGGAGAGTTTCCTGAAGCAGAACCGCGTTGCAGTGGAGTACATTCCTCTCCGCCACTATTACCACAGACACACCCGCAGCATCTTCTGGGAGTTACAAGTAAATTACTCCGGAAAACTGCACTCAGCAACACAATTACTAAATGATCTGCTTTTCCTATTTGTACATTctggttttaaaggggtcatgGCACGAGGAATCAAATTTCCCTTGATCTTTTGACATATTAGAGGTCTTGGTACCATTA

Function

symbol description
dhcr24 Predicted to enable delta24(24-1) sterol reductase activity. Predicted to be involved in steroid metabolic process. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and membrane. Is expressed in cranial ganglion; lens; solid lens vesicle; telencephalon; and yolk syncytial layer. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Orthologous to human DHCR24 (24-dehydrocholesterol reductase).

GO:

id name namespace
GO:0008202 steroid metabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0016491 oxidoreductase activity molecular_function
GO:0050660 flavin adenine dinucleotide binding molecular_function
GO:0071949 FAD binding molecular_function
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor molecular_function
GO:0000246 delta24(24-1) sterol reductase activity molecular_function

KEGG:

id description
ko00100 Steroid biosynthesis

ZFIN:

id description
ZDB-GENE-041212-73 Predicted to enable delta24(24-1) sterol reductase activity. Predicted to be involved in steroid metabolic process. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and membrane. Is expressed in cranial ganglion; lens; solid lens vesicle; telencephalon; and yolk syncytial layer. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Orthologous to human DHCR24 (24-dehydrocholesterol reductase).

Ensembl:

ensembl_id ENSDARG00000013236

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035327 False 1828 mRNA 0.47 9 7149100 7176810
TCONS_00035328 True 1286 mRNA 0.48 6 7160240 7176809

Neighbor

gene id symbol gene type direction distance location
XLOC_017902 NA coding downstream 9958 7138063 ~ 7139142 (-)
XLOC_017901 si:ch211-121a2.4 coding downstream 15554 7122590 ~ 7133546 (-)
XLOC_017900 si:ch211-121a2.2 coding downstream 68630 7070634 ~ 7080470 (-)
XLOC_017899 sirt5 coding downstream 79488 7052870 ~ 7069612 (-)
XLOC_017898 adcy1a coding downstream 148875 6894886 ~ 7000225 (-)
XLOC_017904 NA coding upstream 15073 7191883 ~ 7211196 (-)
XLOC_017905 dsc2l coding upstream 85624 7262434 ~ 7293837 (-)
XLOC_017906 usp24 coding upstream 266414 7443224 ~ 7583486 (-)
XLOC_017907 NA coding upstream 435345 7612155 ~ 7638652 (-)
XLOC_017908 CR848049.1 coding upstream 469952 7646762 ~ 7648325 (-)
XLOC_017928 CU539064.1 misc upstream 2876595 10053405 ~ 10053701 (-)
XLOC_017896 CT583652.1 non-coding downstream 565430 6581799 ~ 6583670 (-)
XLOC_017894 NA non-coding downstream 668587 6478510 ~ 6480513 (-)
XLOC_017891 NA non-coding downstream 934343 6212846 ~ 6214757 (-)
XLOC_017888 CABZ01062796.1 non-coding downstream 1114030 6028201 ~ 6035070 (-)
XLOC_017909 NA non-coding upstream 774972 7951782 ~ 7953182 (-)
XLOC_017913 NA non-coding upstream 945883 8122693 ~ 8443425 (-)
XLOC_017914 CR388209.2 non-coding upstream 1617692 8794502 ~ 8835094 (-)

Expression


Co-expression Network