XLOC_017931 (meis2a)


Basic Information

Item Value
gene id XLOC_017931
gene name meis2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 10098590 ~ 10120442 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035376
AGGTGTCGAGCTGGTAACACCCACCACGCTTCCCAGGCTCAGTCATCAGGGCTTCAGTCCTTCAAGAGGAACCTGCTTCACTCACCAACACAATCCCAGTTGAGGCAAAGCCTGGGTCGCAAAAAAGAGACCATGAGATccggatagtttttttttttctttttcatttcctTTGCAGCGTTTGCCATGCCAGACACGAGCATCCTATAATTTGGAAAGATTCTTCTGACTTCGGGAAGTCTGATAAGCGTAAATTGCATTAGACAGTCAAATGATTCAAGTGGAGGCATATATTTGACAGGCTGTATGAAGTAAATGTGCCGGTCTTTTATTTAAGTGAACTCGTGCTAAAAAGGAAGCGATCAGAAACTCTTCACAGGACATTCTCTTATCATCTTAACGGATTACCGACAGATCAGTCCTATTAAACCGGATACACAAAAGGAATTAAATCACCCAGATTGTTTCCTCGTTGGATTAGATCGCAGTTTGCTCTAAGCATCAACAGAAGTGTCATATGCTGATGGCTCAACGGTACGAAGACCTTGCCCACTATGGTGGCGGGATGGATGGAGTTGGGGTTCCGACGTCGATGTACGGGGACCCGCACGCGCCTCGGCCCCTGCCGCAGGTTCATCATTTGAATCACGGGCCGCCACCACATGCCAACCAACACTACGGGGCCCACGCACCACACAGCATCATGCCCAGCAGCATGGGCTCAGCTGTCAACGACGCACTTAAAAGAGACAAGGACCAAATTTACGGGCACCCGTTATTCCCGCTGCTGGCGCTGGTGTTTGAGAAGTGCGAGCTGGCCACATGCACACCGAGAGAGCCGGGAGTCGCTGGAGGAGATGTGTGTTCATCTGATTCATTTAACGAGGACATCGCTGTGTTTGCCAAACAGATTCGTGCAGAGAAGCCGTTATTTTCCTCTAACCCAGAGCTGGATAATTTGATGATTCAGTCAATACAAGTATTACGATTTCATCTTTTAGAACTCGAAAAGGTGCACGAGCTTTGCGACAATTTCTGCCATCGGTATATTAGCTGTTTGAAGGGCAAAATGCCTATTGACCTAGTAATTGATGAACGGGATGGATGCAAATCTGACTTCGACGACCTCTCAGGATCATCAACAAATCTCGCAGATCACAATCCAGCATCCTGGAGAGACATGGACGACGCTCACTCCACTCCCTCAGTTGGCACCCCGGGACCCTCCAGCGGAGGACATGCCTCCCAGAGCGGAGACAACAGCAGTGAACTAGGAGATGGCTTGGATAACAGCTTGGCATCTCCGGGAACTGGGGATGAGGACGATCAGGACAAAAAACGGCAGAAGAAAAGAGGAATCTTCCCCAAAGTGGCGACCAACATCATGCGGGCATGGCTCTTCCAACATCTCACGCACCCCTACCCATCTGAAGAGCAGAAGAAGCAGCTAGCACAAGACACAGGCCTCACCATCTTACAAGTGAATAACTGGTTTATCAATGCTCGAAGAAGAATCGTGCAGCCCATGATTGATCAGTCTAACAGAGCCGtaAGTCAAGGAACCGCTTACAGCCCTGATGGTCAGCCTATGGGCGGCTTTGTGCTAGATGGCCAACAACACATGGGTCTTCGGCCTGGCGGTCCCATGGGAGGAATGGGGATGAACATGGGTATGGATGGACAGTGGCACTACATGTAAACGCCTCCCCGCTTCCCAAACCATAAACGTTTTGATGGTGGCCTCAGGAATAGTCCCAGTGCTGGCCGGAATCATGAGGAGTCACATCACATTCATCCTCACCTGATCACTGATCATCTTCATTCGTCACGAGAAACCTCTCACAGACCCCTCCTCACCTAGCCATCAGAATCTCCAGCCAAAGGACTTCCTGCAGGAACACCAACAGAACAAAATACAGACTTGAAGCATTTGTGCCAAAAGAGAGACTTCTGAAAAGACAATTGGAGATCTTTtccttttaaattatttatttattcttgttatAACGTCAAGAAGCACGGGGGACCACACCATTTGTGCACTTTGCTCAACCATAGAGTGGCGGTCCCAGAAGAAAATACTCCATACCTCCACAtgcacaagcgcacacacactcatattaaatgcatttaacaGTGGAATATAGTAAAAGATGCTAAAAGCCCTCAAGAACTGAACTGTGAGTGTACAATgacattttgctttgtttttcttttgggaAATGTTCGATGTTTGAGTTTGTGTCATTGACTAGTTTTAGACCTTTGCATTTATGATTCTACACAGTTTGAAGGAAATGAAACCACTGGTGGGATCACTGTAGCACACATCTGACACAAATTCCAGTATCTGAAACCACAAAGTCTTCCCCACATGAGATGCTTTAAAAAGCATCGCTGAAGAAATGAGCTGTGCGTTTATTTGTTGAATTGGAGAGCAACAGTGCTCTTGTAAGGCTAAGTATGCCTGGAGGAGTTTTTAAAACCACTAGAGATGTTCCATTGTACATAATTATGTAAATGTTATTTGTAAAACGCATCAATGTCAAATAGACATTCAGTCGAGAtcctttaaaaaattaagatgggatatttgttgtacattttgGTCCGTTTTCACTCTTGCTTTTCTCTATGGAAAAAAAGTCGATTATATGTTTGTTGATGTACTGGAACGTTTGATCGATTCTCCCGCTCTGTCCATTTTTTCCTTTTAGGAGTCTTTTAAAGCAGTATTTCTACACAGTCAAAAGTCAAATTCTTGTAATAAAGGCTTCATTTTCGAAACGTTAAATCTCTTGTTTTGGATCTTATGTCATTTTCTGGCACTGAATCGATACTGATGCGATATTCGGTTGAAATTAATTTAAGGAAATTCTCGTAGGCATTGATGGCTCCATGAAGAACATTAAATATCTGTACCTTAACTGACAAGTCttgagaatgttttatttttaatatatagagCTTGTAGGTTATTGAAATTATCCAAAGGGGAAAATTATTTTAAGGCAATGCCGTGAATccccatttttaaatatttcatttttaaatgtctataaacaatatcttatttattttgatgACAGATCGCAACTGCTgcacattaattattatttttaatgcataattatTTTCCTTCTCATAAAGAAGCGTGGCCTTTTTAAAATGTAGCCTATAATATTAAGCGTAGCCTAAAAAAAGACGGCGTATAAGGCAATTCCTTATAGAAAAAAGAACAAACGATGAATTTCGATACTGCATAAATAATATCCACTAAAAGACAGCCCGGaaagtgtaaaataataatttcttaactATAGCTACTCATCAAAACAGTTAAAAATCATGTAGGCAAGATGTTTCCTATAAAATCTTCGAGGCAATATGTTAAGAAATAAATCACATTAATTCAATATTTTCAAATCAAGCATCTGGACCGCGAG
>TCONS_00035377
ACACGTGAAGCTGGAAGCCTAACGGCAGGTTTGTGGGACTCGCTGGATCCGAAGAACTAGAAGAAAAGTATCGTGCGGCTCAAACACACATCATGACGGGTCAAGCAAAGGTCAAAACTTGAAATTACAGTGGATTATCGGTTTATCAGCATGGGCGACGAACACTGACATTTAAAGAGGTGTCGAGCTGGTAACACCCACCACGCTTCCCAGGCTCAGTCATCAGGGCTTCAGTCCTTCAAGAGGAACCTGCTTCACTCACCAACACAATCCCAGTTGAGGCAAAGCCTGGGTCGCAAAAAAGAGACCATGAGATccggatagtttttttttttctttttcatttcctTTGCAGCGTTTGCCATGCCAGACACGAGCATCCTATAATTTGGAAAGATTCTTCTGACTTCGGGAAGTCTGATAAGCGTAAATTGCATTAGACAGTCAAATGATTCAAGTGGAGGCATATATTTGACAGGCTGTATGAAGTAAATGTGCCGGTCTTTTATTTAAGTGAACTCGTGCTAAAAAGGAAGCGATCAGAAACTCTTCACAGGACATTCTCTTATCATCTTAACGGATTACCGACAGATCAGTCCTATTAAACCGGATACACAAAAGGAATTAAATCACCCAGATTGTTTCCTCGTTGGATTAGATCGCAGTTTGCTCTAAGCATCAACAGAAGTGTCATATGCTGATGGCTCAACGGTACGAAGACCTTGCCCACTATGGTGGCGGGATGGATGGAGTTGGGGTTCCGACGTCGATGTACGGGGACCCGCACGCGCCTCGGCCCCTGCCGCAGGTTCATCATTTGAATCACGGGCCGCCACCACATGCCAACCAACACTACGGGGCCCACGCACCACACAGCATCATGCCCAGCAGCATGGGCTCAGCTGTCAACGACGCACTTAAAAGAGACAAGGACCAAATTTACGGGCACCCGTTATTCCCGCTGCTGGCGCTGGTGTTTGAGAAGTGCGAGCTGGCCACATGCACACCGAGAGAGCCGGGAGTCGCTGGAGGAGATGTGTGTTCATCTGATTCATTTAACGAGGACATCGCTGTGTTTGCCAAACAGATTCGTGCAGAGAAGCCGTTATTTTCCTCTAACCCAGAGCTGGATAATTTGATGATTCAGTCAATACAAGTATTACGATTTCATCTTTTAGAACTCGAAAAGGTGCACGAGCTTTGCGACAATTTCTGCCATCGGTATATTAGCTGTTTGAAGGGCAAAATGCCTATTGACCTAGTAATTGATGAACGGGATGGATGCAAATCTGACTTCGACGACCTCTCAGGATCATCAACAAATCTCGCAGATCACAATCCAGCATCCTGGAGAGACATGGACGACGCTCACTCCACTCCCTCAGTTGGCACCCCGGGACCCTCCAGCGGAGGACATGCCTCCCAGAGCGGAGACAACAGCAGTGAACTAGGAGATGGCTTGGATAACAGCTTGGCATCTCCGGGAACTGGGGATGAGGACGATCAGGACAAAAAACGGCAGAAGAAAAGAGGAATCTTCCCCAAAGTGGCGACCAACATCATGCGGGCATGGCTCTTCCAACATCTCACGCACCCCTACCCATCTGAAGAGCAGAAGAAGCAGCTAGCACAAGACACAGGCCTCACCATCTTACAAGTGAATAACTGGTTTATCAATGCTCGAAGAAGAATCGTGCAGCCCATGATTGATCAGTCTAACAGAGCCGtaAGTCAAGGAACCGCTTACAGCCCTGATGGTCAGCCTATGGGCGGCTTTGTGCTAGATGGCCAACAACACATGGGTCTTCGGCCTGGCGGTCCCATGGGAGGAATGGGGATGAACATGGGTATGGATGGACAGTGGCACTACATGTAAACGCCTCCCCGCTTCCCAAACCATAAACGTTTTGATGGTGGCCTCAGGAATAGTCCCAGTGCTGGCCGGAATCATGAGGAGTCACATCACATTCATCCTCACCTGATCACTGATCATCTTCATTCGTCACGAGAAACCTCTCACAGACCCCTCCTCACCTAGCCATCAGAATCTCCAGCCAAAGGACTTCCTGCAGGAACACCAACAGAACAAAATACAGACTTGAAGCATTTGTGCCAAAAGAGAGACTTCTGAAAAGACAATTGGAGATCTTTtccttttaaattatttatttattcttgttatAACGTCAAGAAGCACGGGGGACCACACCATTTGTGCACTTTGCTCAACCATAGAGTGGCGGTCCCAGAAGAAAATACTCCATACCTCCACAtgcacaagcgcacacacactcatattaaatgcatttaacaGTGGAATATAGTAAAAGATGCTAAAAGCCCTCAAGAACTGAACTGTGAGTGTACAATgacattttgctttgtttttcttttgggaAATGTTCGATGTTTGAGTTTGTGTCATTGACTAGTTTTAGACCTTTGCATTTATGATTCTACACAGTTTGAAGGAAATGAAACCACTGGTGGGATCACTGTAGCACACATCTGACACAAATTCCAGTATCTGAAACCACAAAGTCTTCCCCACATGAGATGCTTTAAAAAGCATCGCTGAAGAAATGAGCTGTGCGTTTATTTGTTGAATTGGAGAGCAACAGTGCTCTTGTAAGGCTAAGTATGCCTGGAGGAGTTTTTAAAACCACTAGAGATGTTCCATTGTACATAATTATGTAAATGTTATTTGTAAAACGCATCAATGTCAAATAGACATTCAGTCGAGAtcctttaaaaaattaagatgggatatttgttgtacattttgGTCCGTTTTCACTCTTGCTTTTCTCTATGGAAAAAAAGTCGATTATATGTTTGTTGATGTACTGGAACGTTTGATCGATTCTCCCGCTCTGTCCATTTTTTCCTTTTAGGAGTCTTTTAAAGCAGTATTTCTACACAGTCAAAAGTCAAATTCTTGTAATAAAGGCTTCATTTTCGAAACGTTAAATCTCTTGTTTTGGATCTTATGTCATTTTCTGGCACTGAATCGATACTGATGCGATATTCGGTTGAAATTAATTTAAGGAAATTCTCGTAGGCATTGATGGCTCCATGAAGAACATTAAATATCTGTACCTTAA
>TCONS_00035378
AGCATCATGCCCAGCAGCATGGGCTCAGCTGTCAACGACGCACTTAAAAGAGACAAGGACCAAATTTACGGGCACCCGTTATTCCCGCTGCTGGCGCTGGTGTTTGAGAAGTGCGAGCTGGCCACATGCACACCGAGAGAGCCGGGAGTCGCTGGAGGAGATGTGTGTTCATCTGATTCATTTAACGAGGACATCGCTGTGTTTGCCAAACAGATTCGTGCAGAGAAGCCGTTATTTTCCTCTAACCCAGAGCTGGATAATTTGATGATTCAGTCAATACAAGTATTACGATTTCATCTTTTAGAACTCGAAAAGGTGCACGAGCTTTGCGACAATTTCTGCCATCGGTATATTAGCTGTTTGAAGGGCAAAATGCCTATTGACCTAGTAATTGATGAACGGGATGGATGCAAATCTGACTTCGACGACCTCTCAGGATCATCAACAAATCTCGCAGATCACAATCCAGCATCCTGGAGAGACATGGACGACGCTCACTCCACTCCCTCAGTTGGCACCCCGGGACCCTCCAGCGGAGGACATGCCTCCCAGAGCGGAGACAACAGCAGTGAACTAGGTAAGATAAGCTGCCTGTTTAACTGTTACTTAATGATATGCATTGCTGAAAAGATTTTAAGACTTGCTACTCTTGGATTTTAAATTATGTTCATAGGACAAAGATAAAAAGGGGAATAAGAGTAACACACCATTGTTTTCTGAAATTTTGAAATGTACACTGGTTAattaaattctttaaataaaaaaaaatcacataaattatcattaatgttttacagaaaatgttttacagtaattatttactaattttttgTTAAGGGTAGC

Function

symbol description
meis2a Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic viscerocranium morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; nervous system; neural plate; and neural rod. Human ortholog(s) of this gene implicated in cleft palate, cardiac defects, and intellectual disabillity. Orthologous to human MEIS2 (Meis homeobox 2).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0009880 embryonic pattern specification biological_process
GO:0009887 animal organ morphogenesis biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0001654 eye development biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0007420 brain development biological_process
GO:0048703 embryonic viscerocranium morphogenesis biological_process
GO:0005634 nucleus cellular_component
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020122-2 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic viscerocranium morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; nervous system; neural plate; and neural rod. Human ortholog(s) of this gene implicated in cleft palate, cardiac defects, and intellectual disabillity. Orthologous to human MEIS2 (Meis homeobox 2).

Ensembl:

ensembl_id ENSDARG00000077840

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035376 False 3446 mRNA 0.43 13 10098590 10118818
TCONS_00035377 False 3104 mRNA 0.45 14 10099109 10120442
TCONS_00035378 True 843 lncRNA 0.42 6 10114028 10117997

Neighbor

gene id symbol gene type direction distance location
XLOC_017930 NA coding downstream 20375 10077157 ~ 10078215 (-)
XLOC_017929 znf770 coding downstream 33460 10057750 ~ 10065130 (-)
XLOC_017927 ACTC1 coding downstream 118272 9970786 ~ 9980318 (-)
XLOC_017926 gjd2b coding downstream 134877 9958506 ~ 9963713 (-)
XLOC_017925 AL645822.1 coding downstream 192206 9906268 ~ 9906384 (-)
XLOC_017932 BDKRB2 coding upstream 166619 10287061 ~ 10288156 (-)
XLOC_017933 NA coding upstream 227341 10347783 ~ 10422813 (-)
XLOC_017934 glrx5 coding upstream 363573 10484015 ~ 10487951 (-)
XLOC_017935 NA coding upstream 859016 10979458 ~ 10992289 (-)
XLOC_017936 NA coding upstream 890755 11011197 ~ 11016927 (-)
XLOC_017928 CU539064.1 misc downstream 44889 10053405 ~ 10053701 (-)
XLOC_017915 CR388209.1 non-coding downstream 1161586 8936903 ~ 8937004 (-)
XLOC_017914 CR388209.2 non-coding downstream 1263496 8794502 ~ 8835094 (-)
XLOC_017913 NA non-coding downstream 1655165 8122693 ~ 8443425 (-)
XLOC_017937 NA non-coding upstream 976951 11097393 ~ 11178022 (-)
XLOC_017938 NA non-coding upstream 1504462 11624904 ~ 11629535 (-)

Expression


Co-expression Network