XLOC_017934 (glrx5)


Basic Information

Item Value
gene id XLOC_017934
gene name glrx5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 10484015 ~ 10487951 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035382
AAGAGGTGGAGCTTGAGTCCAGTCTCCAGTGAGTTCTACGTCGCGGCAAAAGAGAAGTGACAAACGAACTTAAACTGCTTCAAATATCCCCCTAAACCGCGCAGACTTGCACAATGAATAGCGTTTTTAGGTCGACAGCGCGGTGTCTTCGCTCGGCGACATGGCAGTACAAAACCGCGCATAAGAACGGGGAGCTGTCGGTCGGCAGGGCCCGTCTCATGTGCTCCTCAGCGGGACAGAAGAACCTGGAGGAGATGGTGAAGAAGGACAAGGTGGTCGTGTTCATGAAAGGCACTCCGGCTCAGCCCATGTGCGGCTTCAGCAACGCCGTCGTTCAGATCCTCAGGATGCACGGAGTCGATAATTACGCTTCTTATAACGTGTTGGATGACCAGGATGTCAGACAAGGAATAAAGACTTTCTCCAACTGGCCGACGATCCCACAGGTGTTCTTCAATGGCGAGTTTGTCGGCGGCTGTGATATTCTACTTCAGATGCATCAGAGTGGAGACCTGGTGGAGGAACTGCAGAAGCTGGGAATTAGATCAGCTCTTCTAGATCAAGAAAAGGAGTCAAAGTAAGGAGTCTAGTCTTTGGGATGATGGTCCATTGATATAAACCCTCCAAAGCTTGATTTGACCTGCTGAAGTCCAGAGTCTCCTCAGAAGACTGAAGGAAGTGATGGCAAATCCTGACAACAAAAATCACTGTAAAACACTTGATAGAAAATACACATGATGATTACATTTCTATTGCAGTATATTTGTCTTTATTTCAGATACTCTAATGTTAGACCACTGCAtatgtaaaatgttgtattttgaaagatattattaaatgtattttagatGTATATCACTCTTTttgtcaataaaatattttaaagcattca

Function

symbol description
glrx5 Predicted to enable 2 iron, 2 sulfur cluster binding activity; metal ion binding activity; and protein-disulfide reductase activity. Acts upstream of or within hemopoiesis and iron-sulfur cluster assembly. Located in mitochondrion. Is expressed in cardiovascular system; immature eye; intermediate cell mass of mesoderm; and liver. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 3. Orthologous to human GLRX5 (glutaredoxin 5).

GO:

id name namespace
GO:0030097 hemopoiesis biological_process
GO:0045454 cell redox homeostasis biological_process
GO:0016226 iron-sulfur cluster assembly biological_process
GO:0005759 mitochondrial matrix cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0046872 metal ion binding molecular_function
GO:0009055 electron transfer activity molecular_function
GO:0051536 iron-sulfur cluster binding molecular_function
GO:0051537 2 iron, 2 sulfur cluster binding molecular_function
GO:0015035 protein disulfide oxidoreductase activity molecular_function
GO:0015036 disulfide oxidoreductase activity molecular_function

KEGG:

id description
ko03110 Chaperones and folding catalysts
ko03029 Mitochondrial biogenesis

ZFIN:

id description
ZDB-GENE-040426-1957 Predicted to enable 2 iron, 2 sulfur cluster binding activity; metal ion binding activity; and protein-disulfide reductase activity. Acts upstream of or within hemopoiesis and iron-sulfur cluster assembly. Located in mitochondrion. Is expressed in cardiovascular system; immature eye; intermediate cell mass of mesoderm; and liver. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 3. Orthologous to human GLRX5 (glutaredoxin 5).

Ensembl:

ensembl_id ENSDARG00000043665

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035382 True 892 mRNA 0.45 2 10484015 10487951

Neighbor

gene id symbol gene type direction distance location
XLOC_017933 NA coding downstream 61202 10347783 ~ 10422813 (-)
XLOC_017932 BDKRB2 coding downstream 195859 10287061 ~ 10288156 (-)
XLOC_017931 meis2a coding downstream 363573 10098590 ~ 10120442 (-)
XLOC_017930 NA coding downstream 405800 10077157 ~ 10078215 (-)
XLOC_017929 znf770 coding downstream 418885 10057750 ~ 10065130 (-)
XLOC_017935 NA coding upstream 491507 10979458 ~ 10992289 (-)
XLOC_017936 NA coding upstream 523246 11011197 ~ 11016927 (-)
XLOC_017937 NA coding upstream 609442 11097393 ~ 11178022 (-)
XLOC_017938 NA coding upstream 1136953 11624904 ~ 11629535 (-)
XLOC_017939 AL929349.1 coding upstream 1141930 11629881 ~ 11634468 (-)
XLOC_017928 CU539064.1 misc downstream 430314 10053405 ~ 10053701 (-)
XLOC_017925 AL645822.1 non-coding downstream 577631 9906268 ~ 9906384 (-)
XLOC_017915 CR388209.1 non-coding downstream 1547011 8936903 ~ 8937004 (-)
XLOC_017914 CR388209.2 non-coding downstream 1648921 8794502 ~ 8835094 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G220477 NA non-coding CI01000051 null 5072746 ~ 5074893 (-)
mexican tetra (Astyanax mexicanus) LOC111195232 NA non-coding NC_035917.1 CM008320.1 14953444 ~ 15001573 (-)