XLOC_018086 (cyp2ad2)


Basic Information

Item Value
gene id XLOC_018086
gene name cyp2ad2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 25534669 ~ 25542183 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035634
GACTGCAGAGTTCAGATAAGACGAGGGGAACGTGACATTTTCTCCACCACCATGATCCTGCACCTGATATATGACAGCTTTGATTTTAAAAGCTGGAtcattttctttgttgtttttctgaTCATTGCTGAAATGATCAAAAATAGGACTCCATCCAATTACCCACCAGGACCCTGGCCTTTGCCATTCCTGGGAACTGTCTTCACTAAAATGGATTTTAAGAACATAAATAAGTTGGCTAAAGTCTATGGGAAGGTGTTCAGCTTAAGAGTGGGAAGCGAGAAAATGATAATTGTGTCTGGATATAAAATGGTAAAGGAGGCCCTCGTCACTCAGAATGATAGCTTCGTTTTGCGTCCACCAGTCCCTCTGTTTCACAAAGTTTACAAGGGAATCGGTTTAACAATGAGTAATGGATACATCTGGCGGTCACATAGGAGGTTTGCGGCTTCCCATTTGCGGACTTttggagaggggaaaaaaaacctgGAGCTCGGCATCCAGCAAGAGTGTGTCTATCTTTGTGATGCTtttaaggcagaaaaggAACCCTTCAACCCCATATTCATTTTACACGGTGCTGTCTCTAATACCGTTGCCTGTTTGACATTTGGGCAACGCTTTGACTACAATGACGAGTGGTACCAAGAAATTCTGCGTCTTGACAACCAGTGTGTTCAATTGGCAGGTTCTCCAAGAGTACAGCTGTATAATGCATTTCCTAAGCTCCTGGACTATTTGCCCGGCCCTCACCAAAAAGTATTTTCTAACTATAAGAAGATTACACAGTCCTTGAAAGACGAGATTATTAAGCACAGAGAGGACTGGGACCCTGCAAACCCACGTGACTTTATCGACAACTACCTGACTGAGATGGAAAAGAAAAAGAGTGACCCTCAAGCTGGCTTTAACATAGAAAGTTTAATCATTTCTTGCCTAGACATAGTTGAGGCTGGGACAGAGACGGGTGCGACTACATTACGCTGGGGTCTGCTTTTTATGATCAAGTTCCCAGAAATACAGAAAAAAGTCCAGGCAGAGATAGACAGAGTGATTGGACAGTCACGTCAACCCTGCTTGGATGACAGAGTTAATATGCCCTATACTGAAGCTGTTTTACATGAGATTCAAAGATTTGGGGATGTTGTTCCACTTGGATTCCCCAAACAAGCAGCTGTAGACACAAAAATTGGGAACTACTTCATTCCAAAGGGGACTTCTATTACAACAAACCTGTCTTCGGTCCTGCATGATCCAAACGAATGGGAAACCCCAGACACTTTCAACCCTGGACACTTCCTAGATAAAAATGGCCAGTTCCGGAAAAGAGATGCCTTCCTGCCTTTTTCCGCAGGTAAAAGAGCTTGTGTCGGAGAGCTGCTGGCTCGTAATGTGCTCTTCCTCTTCTTCACCTCTCTGCTGCAGCAGTTCACCCTCTCCAAATGTCCAGGAGAGGAACCCAGTTTGGAGGGCGAGATTTGGTTCACTTACGCTCCTGCTCCTTTTCGCATTTCAGTCTCTGTACGTTAGAACAAAGTCATTTAAACGGGACAGAAGTGTTTGTGTCTTAGAAACTGCAGCAGTGTTTCAGTGTTGTAGcagtttaaatgtaaatgtatcagTACAGTAGGGGATTTACAGATATGTCGATACATATTTCTTTATATCATTTCTATGTCTTAGGAAATGCAACAGTATTAAAGTGTTAGTAGAAGTtttgattttaatgtttaaatctgCATGTATCAGTACAGCAAGTGATTTACAGATATGTCGATATATAATTCTCATGTAAATAAATGACACGTGAATTGATTATTTGTCACATTAAATATCCCTTTGCACAGTGTCATGCAAAAACTCTTTGAGTTACCATTACTAATAAACTAAAGTTTCATAGAC
>TCONS_00035635
GAGGACTGGGACCCTGCAAACCCACGTGACTTTATCGACAACTACCTGACTGAGATGGAAAAGAAAAAGAGTGACCCTCAAGCTGGCTTTAACATAGAAAGTTTAATCATTTCTTGCCTAGACATAGTTGAGGCTGGGACAGAGACGGGTGCGACTACATTACGCTGGGGTCTGCTTTTTATGATCAAGTTCCCAGAAATACAGAAAAAAGTCCAGGCAGAGATAGACAGAGTGATTGGACAGTCACGTCAACCCTGCTTGGATGACAGAGTTAATATGCCCTATACTGAAGCTGTTTTACATGAGATTCAAAGATTTGGGGATGTTGTTCCACTTGGATTCCCCAAACAAGCAGCTGTAGACACAAAAATTGGGAACTACTTCATTCCAAAGTCTGAACAAATCCAGTAGATTTCATTCTCTCTTTATTAGGGGACTTCTATTACAACAAACCTGTCTTCGGTCCTGCATGATCCAAACGAATGGGAAACCCCAGACAC
>TCONS_00035636
GTTTAACAATGAGTAATGGATACATCTGGCGGTCACATAGGAGGTTTGCGGCTTCCCATTTGCGGACTTttggagaggggaaaaaaaacctgGAGCTCGGCATCCAGCAAGAGTGTGTCTATCTTTGTGATGCTtttaaggcagaaaaggCTGTATAATGCATTTCCTAAGCTCCTGGACTATTTGCCCGGCCCTCACCAAAAAGTATTTTCTAACTATAAGAAGATTACACAGTCCTTGAAAGACGAGATTATTAAGCACAGAGAGGACTGGGACCCTGCAAACCCACGTGACTTTATCGACAACTACCTGACTGAGATGGAAAAG

Function

symbol description
cyp2ad2 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in intestine; kidney; liver; and spleen. Human ortholog(s) of this gene implicated in hypertension; myocardial infarction; pulmonary hypertension; renal fibrosis; and renal hypertension. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2).

GO:

id name namespace
GO:0042738 exogenous drug catabolic process biological_process
GO:0006082 organic acid metabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0006805 xenobiotic metabolic process biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043231 intracellular membrane-bounded organelle cellular_component
GO:0005737 cytoplasm cellular_component
GO:0008395 steroid hydroxylase activity molecular_function
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020812-2 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in intestine; kidney; liver; and spleen. Human ortholog(s) of this gene implicated in hypertension; myocardial infarction; pulmonary hypertension; renal fibrosis; and renal hypertension. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2).

Ensembl:

ensembl_id ENSDARG00000021172

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035634 False 1902 mRNA 0.42 9 25534669 25542183
TCONS_00035635 False 500 processed_transcript 0.43 4 25537580 25538417
TCONS_00035636 True 327 processed_transcript 0.44 2 25538355 25540754

Neighbor

gene id symbol gene type direction distance location
XLOC_018085 cyp2ad6 coding downstream 930 25525802 ~ 25533739 (-)
XLOC_018084 cyp2n13 coding downstream 11758 25515259 ~ 25522911 (-)
XLOC_018083 si:dkey-183n20.15 coding downstream 48285 25473056 ~ 25486384 (-)
XLOC_018082 mrpl19 coding downstream 89423 25440514 ~ 25445246 (-)
XLOC_018081 itsn2a coding downstream 98280 25359064 ~ 25436389 (-)
XLOC_018087 cyp2ad3 coding upstream 6242 25548425 ~ 25551676 (-)
XLOC_018088 BX322665.2 coding upstream 57922 25600105 ~ 25605285 (-)
XLOC_018089 paics coding upstream 75931 25618114 ~ 25631256 (-)
XLOC_018090 si:dkeyp-117h8.4 coding upstream 97287 25639470 ~ 25645150 (-)
XLOC_018091 CRACD coding upstream 117656 25659839 ~ 25709349 (-)
XLOC_017928 CU539064.1 misc downstream 15480968 10053405 ~ 10053701 (-)
XLOC_018080 NA non-coding downstream 223215 25307795 ~ 25311454 (-)
XLOC_018078 NA non-coding downstream 802360 24729131 ~ 24732309 (-)
XLOC_018077 NA non-coding downstream 1079740 24448007 ~ 24454929 (-)
XLOC_018075 NA non-coding downstream 1262206 24234926 ~ 24272463 (-)
XLOC_018074 NA non-coding downstream 1346038 24187977 ~ 24188631 (-)
XLOC_018092 CR352243.2 non-coding upstream 168608 25710791 ~ 25712415 (-)
XLOC_018102 BX470119.1 non-coding upstream 577156 26119339 ~ 26119459 (-)
XLOC_018103 BX470119.2 non-coding upstream 652543 26194726 ~ 26194841 (-)
XLOC_018107 NA non-coding upstream 903720 26445903 ~ 26458381 (-)

Expression


Co-expression Network