XLOC_018089 (paics)


Basic Information

Item Value
gene id XLOC_018089
gene name paics
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 25618114 ~ 25631256 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00035641
TCCAAAAGCATGCAGATTAAGATTCTGTCCACGTGGTGAAGATGGCATTACTCTGATTGGTTTTTATGAATCGGCAGAGTGTCGTAACGCTTTACTCTCGTGAAAATAAATGAgaAAAACAAATCCCAGCAAGAATGTCTACTGCAACAGAACTAAAACTAGGTCAAAAGCTGAATGAGGGGAAGACCAAGCAGATCTTTGAGATTTTGGATGAGCCGGGTCATGTCCTGGTCCAGTCTAAAGATCAGATCACCGCGGGCAATGCGGTTCGGAAGGATCAGATGGAGGGCAAAGCTGCTATTGCCAACAAGACCACCAGCTGTGTGTTTAAACTTTTACAAGATGCTGGGCTTAAGACCGCATTTGTCAGGCAGCATTCTGACACTGCATTTGTGGCATCTCGATGTGAAATGATACCCATTGAATGGGTCTGCAGACGTATCGCCACGGGTTCCTTCCTCAAACGCAACCCTGGGGTTAAAGAGGGCTACCGCTTCACTCCTTTAAAAATGGAGATGTTTTTTAAGGATGATGCCAATAATGACCCTCAATGGTCAGAAGAGCAGCTGTTGGCAGCTGGTTTTGACCTGGCTGGACTGACTATTGGTCGCTGTGAGGTGGACATCATGAGCAAAAGCACTGTGGCCATTTTTGAAGTCCTGGAGAAGGCTTGGGCCACCCAGGACTGCACGCTGGTGGATATGAAAATAGAATTTGGAGTAAATGTGACCACTAAGGAGATTGTGCTGGCTGATGTGATTGACAATGACTCATGGAGGCTCTGGCCAGCTGGGGATCGCAGCCAGCAGAAAGACAAACAGGTGTACCGTGACCTGAAAGAAGTCACTCCCGAGGCCATGCAGATGGTAAAGAGGAACTTCGAGTGGGTCGCAGAGCGAGTTAAGCTGCTCCTGGAGTCCCAGGCGAGAGGAAGGGTGGTAGTTATGATGGGCTCCACCTCAGATGTGGCTCACTGTGAGAAGATCCGTAAAGCTTGTGCTTCATATGGCATTCCCTGCCACCTCAGAGTCAACTCTGCCCATAAAGGCCCTGATGAGACACTCCGCATCAAAGCTGAATATGAGGGCGATGGAGAACCTACTATCTTTGTTGCAGTGGCAGGCAGAAGTAACGGCTTGGGTCCTGTGATGTCAGGAAACACTGCTTATCCAGTCATTAACTGTCCCCCTGTAACCCCTGACTGGGGAGCTCAGGACATCTGGTCGTCTCTTCGCATGCCTAGTGGTCTGGGCTGCTCCACTGTTCTTTCTCCTGAAGCTGCTGCTCAGTTTGCAGCGCAGATCCTGGGTCTAAACAACCATTTGATTTGGGCCAAACTTCGTGCATCCATGCTGAACACCTGGGTCTCCCTGAAACAGGCTGATAAAAAGATGCAAGACTGCAGCCTTTAATAAACCATCCCTTTTTGCATTTCCAACTGATATTTTTGTGCACACAGCAGTCATTGCCTTTGACAAGCCTGTGTGAAATGCTGACCTAGAGTTTGTTTGCAATAACAACATTTCAAGTGTAAATCTATATCAATAAAACATTCCTCATTGACA
>TCONS_00035642
CTCGTAAGACCAAAACACCAGTTTAAAAATCCAAGTTAGAGCAGATGGATaataaagttgttgttgtttttttgtccaAGAAAAGCAATTTTTGTCAAATCGATAACACAAAGTCGAAACTGCTCAATAGCTTGCGTCACGCGCCCAAACTTCAATGCAGTTATAAAGAAGTGTTGTAGGGAGaatgtttgcgtctaaacattatCATTCAATAGATAAAACGTCTATATTCCAAAAGCATGCAGATTAAGATTCTGTCCACGTGGTGAAGATGGCATTACTCTGATTGGTTTTTATGAATCGGCAGAGTGTCGTAACGCTTTACTCTCGTGAAAATAAATGAGTTGAGTCTCACCCCTCACCCTTCTTCTTCGTCGAACTTTATAATAAGCCTTCATCTCAAGCACAGCGCGCGTGTCTTAAACCCGAGCACACCGAATAAAGTTcctcatcatttattttattttgcaggaAAAACAAATCCCAGCAAGAATGTCTACTGCAACAGAACTAAAACTAGGTCAAAAGCTGAATGAGGGGAAGACCAAGCAGATCTTTGAGATTTTGGATGAGCCGGGTCATGTCCTGGTCCAGTCTAAAGATCAGATCACCGCGGGCAATGCGGTTCGGAAGGATCAGATGGAGGGCAAAGCTGCTATTGCCAACAAGACCACCAGCTGTGTGTTTAAACTTTTACAAGATGCTGGGCTTAAGACCGCATTTGTCAGGCAGCATTCTGACACTGCATTTGTGGCATCTCGATGTGAAATGATACCCATTGAATGGGTCTGCAGACGTATCGCCACGGGTTCCTTCCTCAAACGCAACCCTGGGGTTAAAGAGGGCTACCGCTTCACTCCTTTAAAAATGGAGATGTTTTTTAAGGATGATGCCAATAATGACCCTCAATGGTCAGAAGAGCAGCTGTTGGCAGCTGGTTTTGACCTGGCTGGACTGACTATTGGTCGCTGTGAGGTGGACATCATGAGCAAAAGCACTGTGGCCATTTTTGAAGTCCTGGAGAAGGCTTGGGCCACCCAGGACTGCACGCTGGTGGATATGAAAATAGAATTTGGAGTAAATGTGACCACTAAGGAGATTGTGCTGGCTGATGTGATTGACAATGACTCATGGAGGCTCTGGCCAGCTGGGGATCGCAGCCAGCAGAAAGACAAACAGGTGTACCGTGACCTGAAAGAAGTCACTCCCGAGGCCATGCAGATGGTAAAGAGGAACTTCGAGTGGGTCGCAGAGCGAGTTAAGCTGCTCCTGGAGTCCCAGGCGAGAGGAAGGGTGGTAGTTATGATGGGCTCCACCTCAGATGTGGCTCACTGTGAGAAGATCCGTAAAGCTTGTGCTTCATATGGCATTCCCTGCCACCTCAGAGTCAACTCTGCCCATAAAGGCCCTGATGAGACACTCCGCATCAAAGCTGAATATGAGGGCGATGGAGAACCTACTATCTTTGTTGCAGTGGCAGGCAGAAGTAACGGCTTGGGTCCTGTGATGTCAGGAAACACTGCTTATCCAGTCATTAACTGTCCCCCTGTAACCCCTGACTGGGGAGCTCAGGACATCTGGTCGTCTCTTCGCATGCCTAGTGGTCTGGGCTGCTCCACTGTTCTTTCTCCTGAAGCTGCTGCTCAGTTTGCAGCGCAGATCCTGGGTCTAAACAACCATTTGATTTGGGCCAAACTTCGTGCATCCATGCTGAACACCTGGGTCTCCCTGAAACAGGCTGATAAAAAGATGCAAGACTGCAGCCTTTAATAAACCATCCCTTTTTGCATTTCCAACTGATATTTTTGTGCACACAGCAGTCATTGCCTTTGACAAGCCTGTGTGAAATGCTGACCTAGAGTTTGTTTGCAATAACAACATTTCAAGTGTAAATCTATATCAATAAAACATTCCTCATTGACA
>TCONS_00035643
CACTTACCTGTGCTGTAAAGCAACAAGTCCAAGTGTCAGAATCTGCGCGACCTCCAGTTGTGTTGGCCATTCGCCCGCCGCCACACATCCGAACACCCCGCACTCCTCTCCGATGCCCGACTCCTCAAACTCCATGTCCTCGTCTCAGTGGAGCTCACTGGGTTGGTAGTGTTAGTTAGCGTGTTTCCACGCTGGCTAGAGTCACCCGAAGCACGTGTTTCCTCGCACAGCGGAACACGCAGAAGAGGATCTGGCAACCCAGCAGCTCgaAAAACAAATCCCAGCAAGAATGTCTACTGCAACAGAACTAAAACTAGGTCAAAAGCTGAATGAGGGGAAGACCAAGCAGATCTTTGAGATTTTGGATGAGCCGGGTCATGTCCTGGTCCAGTCTAAAGATCAGATCACCGCGGGCAATGCGGTTCGGAAGGATCAGATGGAGGGCAAAGCTGCTATTGCCAACAAGACCACCAGCTGTGTGTTTAAACTTTTACAAGATGCTGGGCTTAAGACCGCATTTGTCAGGCAGCATTCTGACACTGCATTTGTGGCATCTCGATGTGAAATGATACCCATTGAATGGGTCTGCAGACGTATCGCCACGGGTTCCTTCCTCAAACGCAACCCTGGGGTTAAAGAGGGCTACCGCTTCACTCCTTTAAAAATGGAGATGTTTTTTAAGGATGATGCCAATAATGACCCTCAATGGTCAGAAGAGCAGCTGTTGGCAGCTGGTTTTGACCTGGCTGGACTGACTATTGGTCGCTGTGAGGTGGACATCATGAGCAAAAGCACTGTGGCCATTTTTGAAGTCCTGGAGAAGGCTTGGGCCACCCAGGACTGCACGCTGGTGGATATGAAAATAGAATTTGGAGTAAATGTGACCACTAAGGAGATTGTGCTGGCTGATGTGATTGACAATGACTCATGGAGGCTCTGGCCAGCTGGGGATCGCAGCCAGCAGAAAGACAAACAGGTGTACCGTGACCTGAAAGAAGTCACTCCCGAGGCCATGCAGATGGTAAAGAGGAACTTCGAGTGGGTCGCAGAGCGAGTTAAGCTGCTCCTGGAGTCCCAGGCGAGAGGAAGGGTGGTAGTTATGATGGGCTCCACCTCAGATGTGGCTCACTGTGAGAAGATCCGTAAAGCTTGTGCTTCATATGGCATTCCCTGCCACCTCAGAGTCAACTCTGCCCATAAAGGCCCTGATGAGACACTCCGCATCAAAGCTGAATATGAGGGCGATGGAGAACCTACTATCTTTGTTGCAGTGGCAGGCAGAAGTAACGGCTTGGGTCCTGTGATGTCAGGAAACACTGCTTATCCAGTCATTAACTGTCCCCCTGTAACCCCTGACTGGGGAGCTCAGGACATCTGGTCGTCTCTTCGCATGCCTAGTGGTCTGGGCTGCTCCACTGTTCTTTCTCCTGAAGCTGCTGCTCAGTTTGCAGCGCAGATCCTGGGTCTAAACAACCATTTGATTTGGGCCAAACTTCGTGCATCCATGCTGAACACCTGGGTCTCCCTGAAACAGGCTGATAAAAAGATGCAAGACTGCAGCCTTTAATAAACCATCCCTTTTTGCATTTCCAACTGATATTTTTGTGCACACAGCAGTCATTGCCTTTGACAAGCCTGTGTGAAATGCTGACCTAGAGTTTGTTTGCAATAACAACATTTCAAGTGTAAATCTATATCAATAAAACATTCCTCATTGACA
>TCONS_00035644
AAAGTCAACAGGGAGGGGGAGAAGAGAGGATAAAGGCAGAGGCGCACCAACAGAAGCCATTTCTAGGAGAGCTTAGAAACATGGAGCCTGAAACAGACCCACAAAGGCACGCTGGAGAGGACAAGAGACAGAGGGACACAGCTGGTCACTGGAGAGGAGAGGAAGTGAAAACTCTGCTCACAGTGTGGAGGGAAAGACTAGCCTGGGAAGAGGAAGAGAGCAGGGCCAAGTATGAGGCCATCTCAAGCCGCCTAAGAGAGCTTGGTGTGTGTAAAGACTGGCTTGAATGCAAGGCCCAGAGTAGGAGAATGGCTCTTCCAGACTGGAGGCCACCGCAGGGCATCTACAAACGATCTGCTGCTGATAGCAGGACGCCAATCCAAAGGCCTTACATGACAGAAGAAGAGCCCACGACTGGCAGAAGAGAGGAGGCTACTGCAGTGCCAGGTCTTCAGGAAGGTCTGGAAGGAGGCAGACACTGGTCTGACAAGGAGGTTCGAGCTCTCCTTACTGTTTGGGGAGACAAGGAGGTTCATAAACAGCTCCAACGCTCCCACAGAAACAAGGCCATCTTTCAGGAGATGGCACACCGGCTGGAGCGCCAACATGGCGTGGTGCGAGACTGGAGACAGTGCCGCACCAAATACAAGAACATGAAATATGATTACAAAGTCAGCAAGAGTCAAGGCCGGCCAATAAGGTTCTTTGCTGAGCTTGATGCAATAATGCAGGGAAAAGAATTTGAGGGTAGATTTGAGGATGATGAGTCACCTAGGAATATACCAAACAGGGATCACCTGGCCATGAGGCGTGAACCTATGGAAGAGCAGGTTATCAAGATTGATGATGATGAAAGTCTAGCAGAGATGCAAACTATGATGAATGCTGCCACTCACCCACTGATCCCAAGAGATTCAACGTCAACATCAGCATCTGCAACTGAGATGAATGTCATCACAGTGCATGACTCGGGGAGAAACTGGAGTGAGGATGAAGTGGCTGCACTGCTTCAAATATGGGCCGAAGAAGGAATTCAACGACAGCTTCAGGGCTCAACCAGAAATAAAGACATATTTGTGCAGATTTCACGCAGGCTTCTTCAGCAGGGTGTGGAACGGGACTGGAAACAATGTCGGACCAAGTACAAAAACCTGAAGTATCTCTACCGCTCTCTGCAGAGAGGAAAAGCCGATATCGGAGATCCTCGCCGTGTCATGAGGTTTTACGAACAGTTGGACACACTTTTATCCAAGCCTACTAGAAGTCGAATGAGTTACGCAGAGTTTTCTGAAACAAATCGTTTACGAAGGAGCTCCAGGATGATTACTCCACCATCATTTGAGGAGCCCTCAATGGGTGGACTTCCACAGGAAAACAATGACATTGATGCAGTTAGATTTGACCAGCCACCCATGGATGAGGCACCTTTAGGTTCTCCTGCCACTTCTGCAAGGGTCTTTCAGAGCCAGGCTGAGATCCAAACCTTTTTAACAAGATCAGAAGAAGCATCAAATGTCGAATTTGAGATACCTGTTGTGAATTCCACAATAATGAGGACAACTGGCAGCCCTCAGATAGAATATGAGCAGCATCTTTCCTCTGACTCCATCTCTGCTGTTATATATGATGACAGTAATAAGTACAGAAGGATTTCAGACAACGGCGACCCATCATACACAAGAGGAGAGCATGAGCCGGCTAGAAAAGGGAAAAAGAGGAAAGCTGCAGATGAAGGAGATCGTTTGCTTTGCAAACAGTTTCATCAGAGCACAGACGATGGAGAAAGCAGCACAGATTGGTCAGAGAATATAGACTTCCAATGCAAAGAAGAAGACGATCAATACTTTCCGATCATGGAGATCACATCTGTGTGTTCAATGGCATCTAATGCAATCACGTCTGAACAGTCGgaAAAACAAATCCCAGCAAGAATGTCTACTGCAACAGAACTAAAACTAGGTCAAAAGCTGAATGAGGGGAAGACCAAGCAGATCTTTGAGATTTTGGATGAGCCGGGTCATGTCCTGGTCCAGTCTAAAGATCAGATCACCGCGGGCAATGCGGTTCGGAAGGATCAGATGGAGGGCAAAGCTGCTATTGCCAACAAGACCACCAGCTGTGTGTTTAAACTTTTACAAGATGCTGGGCTTAAGACCGCATTTGTCAGGCAGCATTCTGACACTGCATTTGTGGCATCTCGATGTGAAATGATACCCATTGAATGGGTCTGCAGACGTATCGCCACGGGTTCCTTCCTCAAACGCAACCCTGGGGTTAAAGAGGGCTACCGCTTCACTCCTTTAAAAATGGAGATGTTTTTTAAGGATGATGCCAATAATGACCCTCAATGGTCAGAAGAGCAGCTGTTGGCAGCTGGTTTTGACCTGGCTGGACTGACTATTGGTCGCTGTGAGGTGGACATCATGAGCAAAAGCACTGTGGCCATTTTTGAAGTCCTGGAGAAGGCTTGGGCCACCCAGGACTGCACGCTGGTGGATATGAAAATAGAATTTGGAGTAAATGTGACCACTAAGGAGATTGTGCTGGCTGATGTGATTGACAATGACTCATGGAGGCTCTGGCCAGCTGGGGATCGCAGCCAGCAGAAAGACAAACAGGTGTACCGTGACCTGAAAGAAGTCACTCCCGAGGCCATGCAGATGGTAAAGAGGAACTTCGAGTGGGTCGCAGAGCGAGTTAAGCTGCTCCTGGAGTCCCAGGCGAGAGGAAGGGTGGTAGTTATGATGGGCTCCACCTCAGATGTGGCTCACTGTGAGAAGATCCGTAAAGCTTGTGCTTCATATGGCATTCCCTGCCACCTCAGAGTCAACTCTGCCCATAAAGGCCCTGATGAGACACTCCGCATCAAAGCTGAATATGAGGGCGATGGAGAACCTACTATCTTTGTTGCAGTGGCAGGCAGAAGTAACGGCTTGGGTCCTGTGATGTCAGGAAACACTGCTTATCCAGTCATTAACTGTCCCCCTGTAACCCCTGACTGGGGAGCTCAGGACATCTGGTCGTCTCTTCGCATGCCTAGTGGTCTGGGCTGCTCCACTGTTCTTTCTCCTGAAGCTGCTGCTCAGTTTGCAGCGCAGATCCTGGGTCTAAACAACCATTTGATTTGGGCCAAACTTCGTGCATCCATGCTGAACACCTGGGTCTCCCTGAAACAGGCTGATAAAAAGATGCAAGACTGCAGCCTTTAATAAACCATCCCTTTTTGCATTTCCAACTGATATTTTTGTGCACACAGCAGTCATTGCCTTTGACAAGCCTGTGTGAAATGCTGACCTAGAGTTTGTTTGCAATAACAACATTTCAAGTGTAAATCTATATCAATAAAACATTCCTCATTGACA

Function

symbol description
paics Predicted to enable ATP binding activity; carboxy-lyase activity; and phosphoribosylaminoimidazolesuccinocarboxamide synthase activity. Acts upstream of or within chordate embryonic development; pigmentation; and retina development in camera-type eye. Predicted to be active in cytosol. Is expressed in several structures, including eye; immature eye; midbrain; neural tube; and yolk syncytial layer. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).

GO:

id name namespace
GO:0043009 chordate embryonic development biological_process
GO:0043010 camera-type eye development biological_process
GO:0006164 purine nucleotide biosynthetic process biological_process
GO:0006189 'de novo' IMP biosynthetic process biological_process
GO:0043473 pigmentation biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0005829 cytosol cellular_component
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity molecular_function

KEGG:

id description
ko00230 Purine metabolism

ZFIN:

id description
ZDB-GENE-030131-9762 Predicted to enable ATP binding activity; carboxy-lyase activity; and phosphoribosylaminoimidazolesuccinocarboxamide synthase activity. Acts upstream of or within chordate embryonic development; pigmentation; and retina development in camera-type eye. Predicted to be active in cytosol. Is expressed in several structures, including eye; immature eye; midbrain; neural tube; and yolk syncytial layer. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase).

Ensembl:

ensembl_id ENSDARG00000033539

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00035641 False 1565 mRNA 0.48 10 25618114 25626198
TCONS_00035642 False 1923 mRNA 0.46 9 25618114 25626428
TCONS_00035643 False 1720 mRNA 0.50 10 25618114 25626693
TCONS_00035644 True 3362 mRNA 0.48 15 25618114 25631256

Neighbor

gene id symbol gene type direction distance location
XLOC_018088 BX322665.2 coding downstream 12829 25600105 ~ 25605285 (-)
XLOC_018087 cyp2ad3 coding downstream 66438 25548425 ~ 25551676 (-)
XLOC_018086 cyp2ad2 coding downstream 75931 25534669 ~ 25542183 (-)
XLOC_018085 cyp2ad6 coding downstream 84375 25525802 ~ 25533739 (-)
XLOC_018084 cyp2n13 coding downstream 95203 25515259 ~ 25522911 (-)
XLOC_018090 si:dkeyp-117h8.4 coding upstream 8214 25639470 ~ 25645150 (-)
XLOC_018091 CRACD coding upstream 28583 25659839 ~ 25709349 (-)
XLOC_018092 CR352243.2 coding upstream 79535 25710791 ~ 25712415 (-)
XLOC_018093 chst14 coding upstream 108723 25739979 ~ 25748407 (-)
XLOC_018094 exoc1 coding upstream 221756 25853012 ~ 25878607 (-)
XLOC_017928 CU539064.1 misc downstream 15564413 10053405 ~ 10053701 (-)
XLOC_018080 NA non-coding downstream 306660 25307795 ~ 25311454 (-)
XLOC_018078 NA non-coding downstream 885805 24729131 ~ 24732309 (-)
XLOC_018077 NA non-coding downstream 1163185 24448007 ~ 24454929 (-)
XLOC_018075 NA non-coding downstream 1345651 24234926 ~ 24272463 (-)
XLOC_018102 BX470119.1 non-coding upstream 488083 26119339 ~ 26119459 (-)
XLOC_018103 BX470119.2 non-coding upstream 563470 26194726 ~ 26194841 (-)
XLOC_018107 NA non-coding upstream 814647 26445903 ~ 26458381 (-)
XLOC_018112 NA non-coding upstream 999814 26631070 ~ 26708526 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000325_04655115_04664756 PAICS coding CI01000325 null 4655115 ~ 4664756 (-)