XLOC_018148 (grem1a)



Basic Information


Item Value
gene id XLOC_018148
gene name grem1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 29469753 ~ 29475172 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00035774
GTTTGTTATGGTGCACAAAGACCTTTGTGAACATAGCAGAAGTTTAAACCACTATTAAACTGAGGATGACTAAAGACGCATTAGCTGTCACTATCGTGGTCTTGTGGCTGCTCTGCAATCCGGCGAGGATCAGGGGAACCGGGGGATTTCAAGGCGCCATTCCTCACCCAAATAAATACAGTCCAAACCAGTCGGAGCAGTCACCGCAGACACCGCAGGCCGGTTCCAGGGGAATGGGACCGCCTTCAGCCGGGGACGAGGTGCTGGACTCCAGCCAGGAGGCTTTACACGTAACGGAGCGCCGGTATCTCAAACTCGACTGGTGTAAAACGCAGCCGCTGAAGCTGATGATCTACGAAGACGGATGCCAACCGCGCGCCATCATCAACCGCTTCTGCTACGGACAGTGCAACTCTTTCTACATCCCTCGACACATTTACCAAGAGGATGGCGCGTTCCAGTCGTGCTCCGTGTGCAAGCCCAAAAGTTTTACGACCGTCACTTACACGCTCTTCTGCCCCGGTCAAACTCCCAACACCAAGAAAAAGCGCGTGCGGCGTGTCAAACAGTGCCGCTGCACTTCTGTCGACTTGGATTAAACCTTAACTCACTgactgatgttgttgttgttggctaCATGCGTGCGTTTGTCTTGACTAACATGCTTGACATATATCATTGATATGTGTTTGTTTAGTCAAAACAACAGTCTTAATATTGTGAAGATATTCATCTGATGCAATTTAATGTACTATAAGTAGCCTGTAGTTGTAATTagacatatttttatattattctcCACTGTGTGGAGGAAGATTTGCACATTGATGCAAATATAGTACTCTGTGGCTAGATTTGTAAGATACATAAACGCACACATAAGGCTATATGGGTGTAAATAAGCAAGACCCAAATATACCAAGTAATGTTTTGCTGGCTTTTATATCTGTGTTGTCAAATATATGTGGTGCCATATTTACAATCTTTTTATTCTCCTGATGAAGAAAATACAGGTGACAAATGAAAtgcatgcaaacattttttttataacaatgaACATTTTGTACAGTACTGCATTTACAAGGAACAAAATTACTGTGATTCAATGATAAATCCACATACATGTCGTCAATAAAAAAGGTGTGATGTGCTGAATAAAACAGTTATAGTTTAAAATTATATGATTGTAAATGTACATTATGTTATGTAATGACTTAATATGGCCATAAAAAATACTCAACTTTTGTTACTCAATATGCAAAATAAAGTGACTGCTTTTTTCTAAGTTGAATGCCAA
>TCONS_00035775
AAAACATTTTCGAGTAGTAGGCCTATGACGACACGACACATAATTAATGCACAAGTGTTATAGCTAAAATTAGCCTACAGTTATTGTGCAAGTAATGAGAACAATATGTTTTACTTACTGTACTTACACTTTAAATATATTACCaataaaacacagcagcacgTTTAAATGACAACGTGCCTGTCGTAAACCAATGGCAATTTGTCGAGCTGAGATGATTCGGCTGCTTAGCAACAGAGCAAATGAAGCGTAGAGGAGGAGGACCGTCACCGCATCTCTGCTGAACCCGATATCCTCTCTCTCTGTCCGGATTACATGGTAGGTTTTCTCTTGACGTTAGGTTAGCTGTTTATTCTCTATATAACACActgtgttttatttacatttcctgATATTCGAGTATGCTTCATAATGTGAGTGTGTAACGGCCTATCTGTTTATCAAGCCTGTTTGCTTGTGACGTAGTTATCATAAGATGTGCGTTTTCTCTAAACTCAGTAATATAATCCGTAGCCATTATAGTCCATTTTAGCAttcataatttctgtttaactggtAATATGCGATGTAACAATAGGCTATATATAACGTAATGTTTACATAGGCGTTTTACAGTAGCCTGCAGAGATACATTTATCTTGTGTTTATTGTCGGTGTAGTGAACGTCAGAGATGGGTTCGACTTCAAAAATGACACACACGGTTTTTCTGAGTGTCATCTTCAGCCTGATAGCCGTGGTTTCTGGCCGCAGTCCACGCACTGTGGATCAGGTGTCGGAAGCGGACATCCAGCGCCTGCTTCACGGTGTAATGGAGCAGCTGGGCATCGCGCGGCCCCGGGTCGAATATCCCGCGCACCAGGCCACCAACATAGTTGGTCCTCTCAGCATCCAAGGTGGTGCTCATGAGGGGCTCCAGCATCTCGGGCCGTATGGGAACATCCCTAACATTGTAGCAGAGTTAACAGGGGACAGTGTTCCCAAAGATTTCAGCGAGGACCACGGTTATCCTGACCCTCCCAACCCTTGCCCCCTTGGAAAGACTGCTGCAGATGGGTGTTTAGAAAATTCTCCAGACACTGCAGAGTTCAGTCGAGAGTTCCAGAAACATCAGCACCTTTTTGACCCAGAGCATGACTATCCTGCACTGGCCAAGTGGAATAAAGGACTGTTGTATGAAAAACTGAAGGGTGGGCCAAAGAGAAGAAAAAGGAGTGTTCCAAATCCATATCTGATGGGACAGAGGCTGGATAACGTGGTGGCCAAGAAATCAGTGCCACATTTCCCAGAGGAGGATGAGGTTGAAACCGCTACAAGCAATATCAAGACCTGAACATCATGTTGATCATAAAATCTGTATAATCAACATAACTTATCAGTTTCACAGTAAAGTAAGCACCAAATGATGTGTGATATTCAACTGAATCATATTATTAATAGAGCAACAAATGATGATTgtataacattaatgaatattctCTTGACGCAACTTTTGTTGTAACActatataatcaaataaaatgatgTATATCTTCATGTGCAGATAATTTGAAACATGTGTTCGTGCATCATGATTCATCTAAGTTTATGAATATACAATCTTCATGAAGGAGCTCTAGAAACACAGGACCATCCCCAAAATGCTGTGAATGATGGTAGACTAAGAGGAGGCGTGGACTGCTGCATTCTCTTAAACGTCAGCGCTCAGAACAGAGCTCCATACCTTATTTTGACTCTGACTCGGAATTCTGGATCATTTGGTTCAGTCTATTTTTATCTGTAGTTTGTTATGGTGCACAAAGACCTTTGTGAACATAGCAGAAGTTTAAACCACTATTAAACTGAGGTAAGTCTGCACATCTActgaatatttatttgaaaaacaaacattttatcttaattaaaaataattacttaTTCATATGATTTCAGAAGACAGTAGCAACTGGTTAAAATATGTAGGAAATTAGAACAAGCTTTTTTTTTGAGGGAGAGGGCTTGAAatgtttattacatattttttattattgtaactttaatataaaagctgcattatgttttttttttcgtaaagACAAATATGTTCAatgtatacagtagtcaacatttgaagtggatcaaaactttaaatcaaagtaataaaatattcaacaacacccattcttatcCAATGACAACTTTAAAAGCCtatgattcacttcaaatgttt
>TCONS_00035776
GAGCAAATGAAGCGTAGAGGAGGAGGACCGTCACCGCATCTCTGCTGAACCCGATATCCTCTCTCTCTGTCCGGATTACATGTGAACGTCAGAGATGGGTTCGACTTCAAAAATGACACACACGGTTTTTCTGAGTGTCATCTTCAGCCTGATAGCCGTGGTTTCTGGCCGCAGTCCACGCACTGTGGATCAGGTGTCGGAAGCGGACATCCAGCGCCTGCTTCACGGTGTAATGGAGCAGCTGGGCATCGCGCGGCCCCGGGTCGAATATCCCGCGCACCAGGCCACCAACATAGTTGGTCCTCTCAGCATCCAAGGTGGTGCTCATGAGGGGCTCCAGCATCTCGGGCCGTATGGGAACATCCCTAACATTGTAGCAGAGTTAACAGGGGACAGTGTTCCCAAAGATTTCAGCGAGGACCACGGTTATCCTGACCCTCCCAACCCTTGCCCCCTTGGAAAGACTGCTGCAGATGGGTGTTTAGAAAATTCTCCAGACACTGCAGAGTTCAGTCGAGAGTTCCAGAAACATCAGCACCTTTTTGACCCAGAGCATGACTATCCTGCACTGGCCAAGTGGAATAAAGGACTGTTGTATGAAAAACTGAAGGGTGGGCCAAAGAGAAGAAAAAGGAGTGTTCCAAATCCATATCTGATGGGACAGAGGCTGGATAACGTGGTGGCCAAGAAATCAGTGCCACATTTCCCAGAGGAGGATGAGGTTGAAACCGCTACAAGCAATATCAAGACCTGAACATCATGTTGATCATAAAATCTGTATAATCAACATAACTTATCAGTTTCACAGTAAAGTAAGCACCAAATGATGTGTGATATTCAACTGAATCATATTATTAATAGAGCAACAAATGATGATTgtataacattaatgaatattctCTTGACGCAACTTTTGTTGTAACActatataatcaaataaaatgatgTATATCTTCATGTGCAGATAATTTGAAA
>TCONS_00035777
ACATGGTAGGTTTTCTCTTGACGTTAGGTTAGCTGTTTATTCTCTATATAACACActgtgttttatttacatttcctgATATTCGAGTATGCTTCATAATTGAACGTCAGAGATGGGTTCGACTTCAAAAATGACACACACGGTTTTTCTGAGTGTCATCTTCAGCCTGATAGCCGTGGTTTCTGGCCGCAGTCCACGCACTGTGGATCAGGTGTCGGAAGCGGACATCCAGCGCCTGCTTCACGGTGTAATGGAGCAGCTGGGCATCGCGCGGCCCCGGGTCGAATATCCCGCGCACCAGGCCACCAACATAGTTGGTCCTCTCAGCATCCAAGGTGGTGCTCATGAGGGGCTCCAGCATCTCGGGCCGTATGGGAACATCCCTAACATTGTAGCAGAGTTAACAGGGGACAGTGTTCCCAAAGATTTCAGCGAGGACCACGGTTATCCTGACCCTCCCAACCCTTGCCCCCTTGGAAAGACTGCTGCAGATGGGTGTTTAGAAAATTCTCCAGACACTGCAGAGTTCAGTCGAGAGTTCCAGAAACATCAGCACCTTTTTGACCCAGAGCATGACTATCCTGCACTGGCCAAGTGGAATAAAGGACTGTTGTATGAAAAACTGAAGGGTGGGCCAAAGAGAAGAAAAAGGAGTGTTCCAAATCCATATCTGATGGGACAGAGGCTGGATAACGTGGTGGCCAAGAAATCAGTGCCACATTTCCCAGAGGAGGATGAGGTTGAAACCGCTACAAGCAATATCAAGACCTGAACATCATGTTGATCATAAAATCTGTATAATCAACATAACTTATCAGTTTCACAGTAAAGTAAGCACCAAATGATGTGTGATATTCAACTGAATCATATTATTAATAGAGCAACAAATGATGATTgtataacattaatgaatattctCTTGACGCAACTTTTGTTGTAACActatataatcaaataaaatgatgTATATCTTCATGTGC
>TCONS_00035778
TCGACTTCAAAAATGACACACACGGTTTTTCTGAGTGTCATCTTCAGCCTGATAGCCGTGGTTTCTGGCCGCAGTCCACGCACTGTGGATCAGGTGTCGGAAGCGGACATCCAGCGCCTGCTTCACGGTGTAATGGAGCAGCTGGGCATCGCGCGGCCCCGGGTCGAATATCCCGCGCACCAGGCCACCAACATAGTTGGTCCTCTCAGCATCCAAGGTGGTGCTCATGAGGGGCTCCAGCATCTCGGGCCGTATGGGAACATCCCTAACATTGTAGCAGAGTTAACAGGGGACAGTGTTCCCAAAGATTTCAGCGAGGACCACGGTTATCCTGACCCTCCCAACCCTTGCCCCCTTGGAAAGACTGCTGCAGATGGGTGTTTAGAAAATTCTCCAGACACTGCAGAGTTCAGTCGAGAGTTCCAGAAACATCAGCACCTTTTTGACCCAGAGCATGACTATCCTGCACTGGCCAAGTGGGTGAGTTCACTTTGAAACTGGCTGGAGGAAACTTCAaacttgtaattttaataaaactatttgttTTGTGAATTATGCAGTAA

Function


symbol description
grem1a Predicted to enable BMP binding activity and receptor ligand activity. Predicted to be involved in animal organ morphogenesis and sequestering of BMP from receptor via BMP binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cranial vault; notochord; pectoral fin bud; pronephric duct; and segmental plate. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist).

GO:

id name namespace
GO:0038098 sequestering of BMP from receptor via BMP binding biological_process
GO:0009887 animal organ morphogenesis biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function
GO:0036122 BMP binding molecular_function
GO:0048018 receptor ligand activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040625-1 Predicted to enable BMP binding activity and receptor ligand activity. Predicted to be involved in animal organ morphogenesis and sequestering of BMP from receptor via BMP binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cranial vault; notochord; pectoral fin bud; pronephric duct; and segmental plate. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist).
ZDB-GENE-040426-1687 Predicted to enable enzyme regulator activity. Predicted to be involved in regulation of hormone secretion. Predicted to act upstream of or within neuropeptide signaling pathway. Located in motile cilium. Is expressed in central nervous system; endocrine system; and sensory system. Orthologous to human SCG5 (secretogranin V).

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00035774 False 1297 mRNA 0.41 2 29469753 29471577
TCONS_00035775 False 2207 mRNA 0.39 5 29471151 29475172
TCONS_00035776 False 975 mRNA 0.46 6 29471806 29474936
TCONS_00035777 False 980 mRNA 0.45 6 29471819 29474859
TCONS_00035778 True 563 lncRNA 0.51 3 29473587 29474495

Neighbor


gene id symbol gene type direction distance location
XLOC_018147 NA coding downstream 40291 29426938 ~ 29429462 (-)
XLOC_018146 ryr3 coding downstream 49040 29268444 ~ 29420713 (-)
XLOC_018145 chrm5b coding downstream 239899 29228337 ~ 29229854 (-)
XLOC_018144 thbs1b coding downstream 417362 29036328 ~ 29052391 (-)
XLOC_018143 acot21 coding downstream 513450 28946709 ~ 28956303 (-)
XLOC_018149 actc1a coding upstream 1680 29476852 ~ 29483514 (-)
XLOC_018150 rrm2 coding upstream 17297 29492469 ~ 29499426 (-)
XLOC_018151 BX248136.1 coding upstream 20128 29495300 ~ 29495435 (-)
XLOC_018152 klf11a coding upstream 26893 29502065 ~ 29505863 (-)
XLOC_018153 taf1b coding upstream 38298 29513470 ~ 29533010 (-)
XLOC_017928 CU539064.1 misc downstream 19416052 10053405 ~ 10053701 (-)
XLOC_018140 NA non-coding downstream 605871 28860442 ~ 28863882 (-)
XLOC_018136 BX569801.1 non-coding downstream 857431 28611272 ~ 28612322 (-)
XLOC_018130 NA non-coding downstream 1236161 28233277 ~ 28233592 (-)
XLOC_018129 NA non-coding downstream 1305601 28114764 ~ 28164152 (-)
XLOC_018156 NA non-coding upstream 212463 29687635 ~ 29691465 (-)
XLOC_018158 NA non-coding upstream 314770 29789942 ~ 29834538 (-)
XLOC_018160 NA non-coding upstream 452013 29927185 ~ 29933758 (-)
XLOC_018162 NA non-coding upstream 617087 30092259 ~ 30099019 (-)

Expression



Co-expression Network