mlh1 (mlh1)


Basic Information

Item Value
gene id mlh1
gene name mlh1
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048565.1
NCBI id CM023219.2
chromosome length 95772356
location 61403030 ~ 61418074 (-)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_021606940.2
GTGACACCACTCCGTTATTTTGTCAACAAGGCAGTATTGGTGCATCGTCCAGAAACATACATCTCTTTTCCATAAAATAAATGTGTGCTTTTTCTAACTAGTTTTTATTGTGAAGGCAGATGTCACTGTTTCATGGGAAAACAGAATAATACGAATTACTTAATTATTGCTTAATAATtacttcacttttgttttgaggcGACCTCGGTCTCGGACAGAGCGGGTTACCTGGCTCACGTCCGAGAGGCAGCCCGGTTCCAAATCGAATGCAATCAACTTTCAGCCGGTGCAAAACACGGCTCAACGGGCGCACTGGCGAGATTAATCGAACCCCTCACTCTCCCCCGCGCTTTTAACAACATGTTGTGATGGTGGTAGGATGTTAAGCTAGCTACTCTTATTAAGTAAGGGTGTCCCATTTAAGCAGCTATTTGTGTTACTTCTGATAATATTCACAATCTGAATCAAAGCTAACAGTATGTCCGGGGTGATTCGGAGACTCGATGAGACCGTTGTTAATCGGATTGCTGCTGGAGAAGTTATCCAACGTCCTGCAAATGCTATCAAAGAATTGCTTGAAAACTGTTTAGATGCCAAGTCCACCAACATACAGGtgactgtgaaggaggggggtcTGAAACTTATCCAGATACAAGACAATGGCACTGGCATCAGgAAAGAAGATATGGAAATAGTATGTGAACGGTTTACAACAAGCAAGCTCCAGACTTTTGAGGACCTCAACGCCATCTCAACCTATGGTTTCCGAGGAGAGgcACTTGCCAGTATAAGCCATGTTGCCCATGTGACCATAACAACCAAAACGGCTGACGCCAAGTGTGCTTACAGAGCCACCTACTGCGATGGGAAACTAAAGACCCAACCCAAACCCTGCGCTGGAAACCAGGGGACACAGATCACTGCGGAGGATCTGTTTTATAACGTGTCCACCAGGAGGAAAGCACTGAAGAGCCCCAGTGAGGAGTACTCCAGGATTGTGGAGGTGgtgagcagGTATGCCATACACAACTCTGGGAAAAGCTTTGCTGTCAAAAAGCAAGGCGAGACCATGGCAGACGTCAGGACCCTACCCAACGCCTCCATACTGGATAATATCCGTGTGGTGTTCGGCAATACAGTCAGCAGgGAGCTGATTGAAGTGGGCTGTGAGGATCAGAAGCTTGCCTATAAGCTGAAGGGCCACATCTCCAACGCCAACTACTCAGTGAAGAAGTGCATCCTCATCCTCTTCATCAATCATCGTCTGGTTGAATCGAGTGCCTTAAAAAAAGCCATTGAGACCGTTTATGCTGCATACCTTCCCAAGAACTCTCACCCATTTCTATATCTCAGCCTGGAGATTGCCCCTCATAACATCGACGTGAATGTCCACCCTACCAAACACGAGGTGCACTTCCTCCACGAAGACTGTATCATCGAGAGCGTTCAAAGACAGATAGAGAGCAAACTCCTGGGCTCCAACTCCTCACGCACGTACTTCACACAGACTTTGCTGCCTGGGCTGTCTGTCTCCACCAGCGAGGGGAAGTCTTCCTCCAACTCCACAGGGGACAGTGAGCGGGTCTACGCCCATCAGATGGTCAGGACCGACAGTAGAGCCCAAAAGCTGGACGCCTTTCTCCAGCCGGCGTCCAAGCTGGCCTCTACTCCCACCGCCAACCCTAATGGGCAGAGCAGGGGGGAACCTGTGACCACCAATGACATGGAAGAGATGGACAACGCAGAGATCCTGGAGGAACAGGCGCCAGGTGCCACAGAGGATGGGGAGGGAACCAGCCGAAATACCCCAGCTGATCTCCCCAGGAAGCGTCCCCGTGCCGGTCAGGACAAGGAGCAGGAGGACCTGACTGCTGCAGCCACAACCAGGAGACGAGCCATCAAGCTGAGCAGTGTGAAGGAGCTGAGAGATGACATCGCTGAGCACGCACACAAAGGTCTTCAAGAGATGCTTCAGAATCACTCGTTTGTGGGCTGTGTCAACCCCCAGTGGACTCTGATCCAGCACCATACCAAACTGTACCTTCTCAACACCACCAAACTCAGCCAGGAGCTATTCTACCAAATTTTGATCTACGACTTCGGTAACTTTGGCATCTTGAGGTTATCTGAGCCTGCGCCACTCTATGACCTGGCCATGCTGGCTCTGGACTCCGAGGAGAGCGGCTGGTCGGAGGAGGACGGGCCCAAGGAGGGTCTGGCCCAATACATAGTTGACTTCTTGAAGAAGAAATCTGAGATGCTGGAGGACTACTTCTCCATGGAGATCGACCAGGAAGGAAATCTCACCGGTTTGCCATTGCTGCTTGACAAGTACACCCCTCCTATGGAGGGTCTGCCCATGTTCATCCTACGTTTGGCTACTGAGGTGAACTGGGACAATGAGAAGGACTGCTTCAGAGACTTCAGCAAGGAGTGCAGCCAGTTCTACTCTATCAGGAAACAGTATGTCCTGGAGCTGGAGccgggagaggaggagcagGATGCAGAGCTGAACTCGTGGCGTTGGAAGGTGGAGCATCTCCTGTTTAAATCCTTCCGGAGCCTCTTCAGTCCCCCTAAACACTTCAGTGAGGATGGCAGCGTACTCCAGATTGCTAATCTACCAGACCTCTACAAAGTATTTGAGCGATGCTAAAACATGAGAAACACTGTCCATGGGCTGCATGTCTGTTTCAGGAAACCatttgatatacagttgaagtcggaagtttacatacaccttagccaaatacgtttaatcctagtaaaaatccctgttttaggtcagttaggattaccactttattttaagaatgtgaaatgtcagaataa

Function

symbol description
mlh1 Predicted to enable ATP hydrolysis activity. Acts upstream of or within meiosis I and spermatogenesis. Predicted to be located in nucleus. Predicted to be part of MutLalpha complex. Is expressed in testis. Human ortholog(s) of this gene implicated in Lynch syndrome (multiple); gastrointestinal system cancer (multiple); lung cancer; mismatch repair cancer syndrome; and sporadic breast cancer. Orthologous to human MLH1 (mutL homolog 1).

NR:

description
DNA mismatch repair protein Mlh1 isoform X1

GO:

id name namespace
GO:0006298 mismatch repair biological_process
GO:0043060 meiotic metaphase I plate congression biological_process
GO:0007283 spermatogenesis biological_process
GO:0051026 chiasma assembly biological_process
GO:0007141 male meiosis I biological_process
GO:0005634 nucleus cellular_component
GO:0030983 mismatched DNA binding molecular_function
GO:0005524 ATP binding molecular_function

KEGG:

id description
K08734 MLH1; DNA mismatch repair protein MLH1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_021606940.2 True 2832 mRNA 0.49 19 61403030 61418074

Neighbor

gene id symbol gene type direction distance location
abcc2 mrp2 coding downstream 91053 61246276 ~ 61311977 (-)
LOC118964986 LOC106576846 coding downstream 685730 60715944 ~ 60717300 (-)
LOC110532522 LOC106576846 coding downstream 695984 60695135 ~ 60707046 (-)
LOC110519525 LOC106576846 coding downstream 707505 60660467 ~ 60695525 (-)
gdf10a LOC106576847 coding downstream 864109 60525419 ~ 60538921 (-)
LOC110526202 LOC106576840 coding upstream 305 61418379 ~ 61429118 (-)
LOC110526243 LOC106576835 coding upstream 123610 61541684 ~ 61544247 (-)
dnajc12 djc12 coding upstream 126604 61544678 ~ 61548916 (-)
tial1 tial1 coding upstream 234234 61652308 ~ 61676942 (-)
LOC110526339 mcmbp coding upstream 299380 61717454 ~ 61733606 (-)
G68617 lrrfip2 non-coding downstream 3436 61384295 ~ 61399594 (-)
G68613 NA non-coding downstream 73187 61329572 ~ 61329843 (-)
G68609 NA non-coding downstream 80225 61322148 ~ 61322805 (-)
G67804 NA non-coding downstream 90134 61312637 ~ 61312896 (-)
G67763 NA non-coding downstream 159840 61242464 ~ 61243190 (-)
G68701 NA non-coding upstream 78187 61496261 ~ 61496591 (-)
G68703 NA non-coding upstream 80600 61498674 ~ 61498984 (-)
G68704 NA non-coding upstream 81157 61499231 ~ 61499449 (-)
G68705 NA non-coding upstream 81731 61499805 ~ 61500046 (-)
G68713 NA non-coding upstream 90929 61509003 ~ 61509718 (-)
LOC110526097 LOC106576849 other downstream 941796 60430184 ~ 60495300 (-)
LOC110525695 LOC106576879 other downstream 2247885 59144373 ~ 59199471 (-)
G65147 NA other downstream 2617413 58784742 ~ 58785617 (-)
G63328 NA other downstream 4004542 57397194 ~ 57398488 (-)
G63093 NA other downstream 4340182 57035667 ~ 57062848 (-)
G68736 NA other upstream 264204 61682278 ~ 61686308 (-)
LOC110526417 LOC106576819 other upstream 563657 61981652 ~ 61983330 (-)
G69210 NA other upstream 993448 62411522 ~ 62418296 (-)
G70013 NA other upstream 1859134 63277208 ~ 63277752 (-)
LOC110526867 LOC100136521 other upstream 2951828 64369803 ~ 64384521 (-)

Expression


Co-expression Network