LOC110526236 (sirt1)



Basic Information


Item Value
gene id LOC110526236
gene name sirt1
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_048565.1
NCBI id CM023219.2
chromosome length 95772356
location 61549181 ~ 61561338 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence


>XM_021607034.2
CAGCTGTCGACCGCGGAAGAATGTTTTACCACAGTACACAGCGGCTTTATCAGCTGAAGATGGCGGACGGGGAGAATATCCTTGTTGGAGCCAGTTCCAGCACTTCAACTAATGAAGAACCAGATTCAAAAAAGGCCAAAATGAGCATGGCCATAGAATGTGGACTCAAAATTGTTCAGACTAAGCAAGTTACGTATGGGCCAGAGGCTGGTGAGAGTTTGGCGGCGGCGATTTCTGCGCAGCCAAAGGAGAAGGAGATTGAGCCGGTGATGTCGGTAGGACAGGCCTCAGCAGCAGCACCAGGCGGAGACAATGGGCTGCTGGTCTTCGAGCCTCAGGAAAGTGTAGTGAATTTAGACAAGGCGTCTGGACCCACGGCGGAGCCTGCAGACGGTGTCAATGAGGATGATGACCGATCCTCACATGCAAGTTCCAGTGACTGGACACCTCAACCACAGATAGGTTCCTACAGTTTTATCCAGCAACACATCATGAGAGAGACCGATCCAAGAACAATATTGAAAGACTTGCTTCCTCCAGAGACTGTGCTTCCACCGGACTTGGATGACATGACGCTGTGGCAGATCATCATCAACATTTCGGAGCCTCCTAAAAGAAAGAAGCGGAAAGACATAAACACCCTGGAGGACGTGGTTCGGATACTCCATGAAAGCAAAAAGATCCTTGTGCTTACTGGTGCTGGAGTGTCTGTTTCTTGTGGAATACCAGACTTTCGATCCAGAGATGGCATTTATGCAAGGCTTGCAATAGATTTCCCAGATCTTCCAGACCCTCAAGCAATGTTTGATATAGAGTACTTCAGAAGAGACCCAAGGCCCTTTTTCAAGTTTGCTAAGGAGATCTATCCTGGACAGTTCCAACCTTCGCCCTGTCACAAATTCATATCTATGCTGGGCAAGCATGGGAAGCTACTACGCAACTACACCCAAAACATTGACACTCTTGAACAAGTGGCTGGGGTTCAGAGGATCATCCAGTGTCATGGGTCTTTTGCAACCGCTTCCTGTCTCATCTGTAAACACAAGGTTGACTGTGAGGCTGTAAGGGAAGACATTTTTAATCAGGTTGTCCCTCACTGTCCACGGTGTCGAGATATTCCCCTGGCGATCATGAAGCCAGATATTGTCTTCTTCGGAGAGAATCTTCCAGAACTGTTCCACAGAGCAATGAAGCAGGATAAGGATGAAGTGGACCTCCTTATCGTCATTGGGTCCTCACTGAAAGTGCGACCTGTGGCTCTCATCCCAACCTCCATTCCTCATGAAGTGCCTCAAGTCCTGATTAATCGGGAGCAGCTGCCTCACCTCAACTTTGACGTGGAGCTACTTGGGGACTGTGACGTCATCGTTAACGAGCTCTGCCATCGGTTGGGCGGAGACTTTGAGCAACTGTGCTACAACTCCTTAAGACTCAGTGAGATCACAGAGAAACCCCCGCGGTCACAGACACCTTGTGAGGCCTTGTCCACTCACAGTAAGCCAACAGAAGAAGAACAGAAGACCCGTCACACAGACTCATCGTTCGGTGCCTCAGAGGAGACGGACACTCATACGGTCACAGACACTCCAGAAGGCGACAGAGTACCAACAGAACCTTGTCCGACTGCGCAGAATGACACAGACGCATCTGAAGTCGATGGAGTACCATCGGTGCCCTATCCAAAGACAAAGATTGTCTCTGACACGCTTGAAGTTGGAGTACCAACAGAACCCTGTCCAAAGACTCAGAATGTCACAGGCACCCTGGAAGTCAACAGAGTAGCGACAGAGCCCTGTCCGAAAGACACTCTTGAATTCGATGCAGTGCCATTAGAGCCTAGTCCAAAAGTGCAGATTGTCCCAGAGGCTCCAGAAGAGCCTTGTTCAAAGACTCAGTCCCCCAATGAGGAGAGAATGGAGAATTCAGATTCTCCGTCAGCGGACACGCAAAGGGAAGAACCCTCTGGATTAAATGACCAACATGTCAACCTTGAAGTTCGCCGACGATGCTGGATGAGTCGAATCAGTCGAAGTCCTATCAGCAAGCGCCTTGAGACTTCTCAATACCTATTCCAAGCACCAAATCACTACATCTTCCACGGGGCAGAAGTGTATTCCAACTCGGAGGACGAGACATCCAGCTCCTGCGGGAGCAACAGTGAGGACTCcagcctggaggaggaggaggatgacgaGGAAGAAGACAGTGATGCCGAGGAGGACCAGAGCACACCAGCAGAGGAGGGCGAGGGCTGCCTCATTGACATAGTAACACACAAGCAAGCCTGCGAGGGCACTTCGAGTGTGAAGCAGATGGAGAGTACAGACAAAAATGTTCAGAACACCACAGACCTTTAGAAACACAAAGCACTTGCAgtcttttttaaaaatatttgttttgtatATTTTTGTCCACCCACAGCACGTCCTATTATACATTTTTCTTAAAGTCTAGATTGCGTTGATACTTTTGCATGCATGTGCTGAAAATTCGTTCTTCGTTCTCTTCTGTCTGACCACATTAACAAGCTGCAGGTGGTTTGTTTACACGTTTTGTGTACTACAATTAAATAAACAGCAGCTCAACTCAACCAATCCACTTCAGAAGGTTAAtggtgaagaatgcaacaaagaaaAAACATAGACCAAAGAAcaattctctcccccccccccaatacaccCAACAGTTTTTGCATTAAATCTTAAAAACCTTGTCTTTGACTTTCCTACCACCTGAAGTGTAAAGAATATATTGAGCGGTGGCATTGTTTTCCTTACGATATTTGGCAGCTACTTTTTACAGTCAAGCTTTTATTATTTTTGTACTTTGTAACATGTAAGAGACACACTCAGCAAAGAGCAGGTGATGGTTTTCTAAATGAAATTGAAAACGTTATACATTGTGCAAACATAAAGCCTTAACTGTGTTCAATGAGCTTTCATTGGAGCAAATGTCACTTTTTTCTTCCTTTTCAGCAGTTTGACGCGTTTGTTCATGTTTCCTCGGTTGCATGAGCTATTTGGTCGATGTGACTGATTTGCTCCTATTCATTCTTTCCTGAGAAATGCCCAGCCCTAACACTGAGACCCTGTAGAGCTATACAAGTGTTCTGGGATACGTTTAATATGAGCCAAATTTACTCTTTTAAGCAACTCATTCGAATGAaattaaaatatttgttttgttttgagcTTGATCTTGGTAGTTAAATTGCTAAAATGTTCATTCATAGTAGGCCTTTTCCTTATTTTCATGAGAACACCACAGAAACAGTCTAATTAATCACAAGGTGTGACAACACACTGTTGTGTAGAAAACGGATATAGATATGAGAGTTGCATGCTATTTGACATTTGATGTCCAAGTTTAGTTTGAGAAGACCACTACAGGTAAGTGCATGCAGTTCAGATACTGCAGCAGCGCCATTGGAGCTGGTTTTACGCAAATGGAGGGACAACATTTGCATGGATGAACTAAGATGATTACAATTACATTTAAGAGTTCTTATAATCAGTATGCTGATGTGTGAGAGTCGGCTTTTGTTATGCTCTGCagtgtttattttttacatcaaaacatttatttttcatgTTTTCTTTAAAAATGTATCTGCTATATTTATATTTGGTTTAATAACACCATACACCAACAAATAGGCCATAATATAGCACATAGTCTCATTTGAGGTTACCCTTTATGTAAATATGACTGCCTGTATTTAATTGATAATGAATACTGTATTAACAGTATAGGCCTATGTTTTTAAAGTTCTTATGCCTGCAAAAGTCACAGAAAGAGTTGTGTTTTTGTCTAAAATTACTAATAAAAATTCGGTCAAAATG

Function


symbol description
sirt1 Predicted to enable several functions, including NAD+ binding activity; NAD-dependent histone deacetylase activity; and p53 binding activity. Acts upstream of or within cell migration involved in sprouting angiogenesis; positive regulation of angiogenesis; and regulation of gliogenesis. Predicted to be active in nuclear inner membrane; nucleoplasm; and rDNA heterochromatin. Is expressed in female organism; liver; male organism; and retina. Human ortholog(s) of this gene implicated in Huntington's disease and prostate cancer. Orthologous to human SIRT1 (sirtuin 1).

NR:

description
NAD-dependent protein deacetylase sirtuin-1-like

GO:

id name namespace
GO:0001944 vasculature development biological_process

KEGG:

id description
K11411 SIRT1, SIR2L1; NAD+-dependent protein deacetylase sirtuin 1

RNA


RNA id representative length rna type GC content exon number start site end site
XM_021607034.2 True 3842 mRNA 0.44 9 61549181 61561338

Neighbor


gene id symbol gene type direction distance location
herc4 herc4 coding upstream 8244 61517953 ~ 61540937 (+)
LOC110526212 LOC106576837 coding upstream 43876 61501014 ~ 61505305 (+)
LOC110526206 fam83h coding upstream 60754 61437607 ~ 61488427 (+)
lrrfip2 lrrfip2 coding upstream 147374 61342105 ~ 61401807 (+)
LOC110526122 LOC106576844 coding upstream 322056 61117250 ~ 61227125 (+)
LOC110526250 LOC106576834 coding downstream 274 61561612 ~ 61571769 (+)
mypn mypn coding downstream 11463 61572801 ~ 61623278 (+)
atoh7 atoh7 coding downstream 68587 61629925 ~ 61631527 (+)
pkd2l1 pkd2l1 coding downstream 73825 61635163 ~ 61646181 (+)
bag3 bag3 coding downstream 116442 61677780 ~ 61684168 (+)
G67870 NA non-coding upstream 4981 61541521 ~ 61544200 (+)
G67897 NA non-coding upstream 37346 61511635 ~ 61511835 (+)
G67856 NA non-coding upstream 120617 61423275 ~ 61428564 (+)
G67855 NA non-coding upstream 131454 61417130 ~ 61417727 (+)
G67847 mlh1 non-coding upstream 138565 61409429 ~ 61410616 (+)
G67921 NA non-coding downstream 23126 61584464 ~ 61584663 (+)
G67938 NA non-coding downstream 32239 61593577 ~ 61593781 (+)
G67939 NA non-coding downstream 32556 61593894 ~ 61594121 (+)
G67950 NA non-coding downstream 54055 61615393 ~ 61615668 (+)
G67806 LOC106581772 other upstream 233929 61314874 ~ 61315252 (+)
G66188 NA other upstream 1607117 59941486 ~ 59942064 (+)
G65442 NA other upstream 2224052 59324636 ~ 59325129 (+)
G64338 NA other upstream 2848802 58699296 ~ 58700379 (+)
G64315 NA other upstream 2883275 58665334 ~ 58665906 (+)
G67930 mcmbp other downstream 168427 61729765 ~ 61733388 (+)
G70011 NA other downstream 1713625 63274963 ~ 63275296 (+)
LOC110526969 stk32c other downstream 3248251 64809255 ~ 64946164 (+)
LOC110527164 LOC106576754 other downstream 4354397 65915581 ~ 65922285 (+)
G73515 NA other downstream 4726341 66287679 ~ 66288469 (+)

Expression



Co-expression Network