XLOC_019857 (irs4a)


Basic Information

Item Value
gene id XLOC_019857
gene name irs4a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007132.7
NCBI id CM002905.2
chromosome length 45934066
location 43515673 ~ 43527198 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00039068
ATGGAAGATCGGCCGCGTTTACCGAATCACGGCGTCATGTTGACACTGGAGGCTCAACCGCGTCGCGCTGTCACGAAAACATCCGCGAGCGGCATCTCTTGTGCTGCTGCCGGGGAGCctccatcctcctcctcctcctcctcctcctcctccacctccacctCAATCAATAACAGCGGCTGCCGTTTGCCCATGCACTTATCAGCCTCCTCTCATTGCCAGCCACAGAGGAGGTACCATCCGCCTTACCACTTTAAAGTGCACCATCTGTTCCCGGATGAGAGCCCTCAGGATGCTGTGCTGAGGAAGAACCTGCCAGCCCTACAGTATAAGGTGCACGACTCTGCCTTCTGCCGCGTGCTCAGCGCTGACACCACTGCTGCCGCCCTGGCCGCTGCCGCCGCCTGCTCTGGTGGCCTGGACCGGGACATCTGGAAGTGTGGCTATCTGCGAAAGCAGAAGCACGGCCACAAGAGGTTCTTCGTATTGCGGGGCCCCAGCAACCTCGGGCCCAGCCGCTTGGAGTATTACGACAGCGAGAAAAAATTTCGCAATGCCCTCAAAGCTGCTGCTTCTGGTGTCACGTGCCCTGCCAAAAGGGTGATTTATCTGTCGCAGTGTTTTACGGTTAACAAGAGGGCTGATGCTAAGAACAAATACCTCATTGCCCTTTATACTAAAGACGAATACTTTGCTGTTGTAGCCGAGAGCGAACAGGAGCAAGAAGAGTGGTACTTGTCTATAACGGAACTTATGACGGAGGGCAAAAAGGGGCAGCTGGACAACGACGAACTTGATGATGGCTATGGGACGATTTCGCCGGGAACCATTTTCAAGGAGGTGTGGCAGGTGAACGTTAAGCCTAAAGGCTTAGGTCAGACTCGAAACTTAATGGGGGTGTACCGTCTGTGCCTTTCCGCCAAGACTATTCACCTGGTGAAGCTGAACTCGGAGACGCCTGCCGTCAACCTGCCGCTAATGAACATTCGACGCTGCGGTCACTCCGAGAGCTTCTTCTTTATCGAGGTGGGCCGCTCTTCTTCCATCGGCCCTGGCGAGATATGGGTGCAAGTCGAGGACTCTGTTGTGGCGCAGAACATGCACGAGACCATTCTAGACACTATGAAGGCTCTGAAGGCCTTTCCTGACTTTAGGCCAAGGAGCAAAAGCCAGTCATCTGGCTCAAATCCGCTGCCGTTTATTACGACTCGCCGGCATCTCGGCAATCTCCCCCCAAGCCAAACTGGCCTCCAGCGAGCCTCCCGAACGGATTCAATGACAGGCACGCCGCCCACAGGGAAAAGCAGAGGGCGGGGTCAGCGCTACCGCACCTCTAGCGAGGGCGAAGGCACTCAGGACCGCCCCCTCAGCTCTGGGACGGGCAGCTTGGTGCACATCAATACCCCCATTCTCAGTGTGGGCCGGGAGGAAAGCGGCAGCTGCTGCGCTCATGCATCACCCAATCAGGCCCATCACACCCGCTCCGCATCACTTCCCGTATCTCACTTCCTGTCTGCCACCAGCCCGATCAGTGTGTCCAGCAGTAGTGGGCACGGCTCGGCTTCAGATACACACACTCGACCCTCAAGCTCCTCCATTTGTGGCTCCCCCAGCGACGGAGGCTTCAACTCCTCCGACGAGTTCTGCCCCAGCCCCTGCGACTTCAGGTACTTTCATGCAAGCTGTACCACACCCGAATCCCACGGCAGCACCCCGCCGATTAGGGATGACTACAGGCTGACTGAGTATATGACTATGGATTGGCACAGAGATGGGGCGAGGACGTTCGAGGAGGAGAGCAGTTACATGGAGAGGACTTTCCTGAAGCTGGCACACTCGTCCAAGCCAAAGCTAGGCGGCAGCTTAAGCATCACGCAGCAGAAAGCCACGCAGACCTCATCGTCTTTTGATGAACCGATGGAGTCTAAACGGCAGCAGGTTTGCTCGTGCCTGCTGAAGTCAGCCTATAAGTCTTACTCTGAGTTACATCACCCAAACAAGCCTCCCTTGCTCAGCTCTGAGTGTCAGAAGAAACTGCCAAAAGACGACGGCTACATGCCTATGATCTACAGCATGGCTTCTTCTCCTAATGCAGATTACACCCCTATGCAACCCCGAGCAAACCACCCTGCGTCTCTGGACGTCCACCCCTGTTCCTCGCAGCAGTCGGACCGGTACGGATACATGATGATGCTCCCTAGTGACAGCCCCTCGAGTCGGGAGCAGGCGGAGTACGACGACTACATGGATATGTCACAGCTTACAATAGCTGAAGGCTTTTCTCAAGCCTCGCCCGATTCCCTCAAGGCCTCGTATTTCTCGCTTCCGCGCTCCTACAAAGCCCCGTCACGAGAAAAGCACGAAAAGGCCGAATACGTTCCCATGTCTCCAGCTGATCCCATGAGTCCTCCTAGTCCCGGAGAGTATATTCACATGGACTTTGGTCCTCGTCTCGCTCACCCCGCTCTGTCTCCACCCTCCGCAGACTCGCCCTCCACACCTCCGCCCTCTCAGCCCTGCTACCGGATGTGTTGCTCCTCTCCAGACCATGATTACTTGGGTCTAAACATGGATAATCTCCTAAAGGACCGGCCTCCGCGACACTCCCTCGTTGCTCCATGGAATCCCCCTAATTACGCTCGCCCCTTAGGGTGCTCATACGGACAGACCTCCGCTAATTTAGATCCCGAAAAGGTGCACGGTGAATGCGGAGACGTTCCCTTAAGAACCATGCAGCATCTTTGCATCTCCGAGCGACTGCCGTTCACTCACACGGAGCCCAAAGTCATCAGGGCGGACCCGCAGGGGCGAAGGCGGCACAGTTCGGAGACTTTCATCCCCTCGCCGGCTACCTTTGCTAGTGGTTGCGGAATCAGgccctcagccaatcagaatctccCCGAAGCTAGCAGATGGCAGAGCTCCTTCGATAGCATGTGGTCGCATCCGGACGCCTCCCCGAACTCCGCCACAGGTGGGACGCCTCTGAACACCTCATCCAGCTACCTCAACTACATCGCTCTGGACCTGAGAGAAGTGGCCCGGGTCACACACGACGCTCCACGCCCAGCCCATAGCAACCTCCAAGAGAGCGACGCTTACGCTGGTATAGACTTCTCCGTTTCGGGAGGACGTGCCAATGCCTCAAAAGATTGAGTGAGTCGGATGATGCTGGTGCCCGAAGGGGAATCAGGACACGGAGAATCCACTGAACTCTGGACCGCCCAAGAGGACAGAAACCATCCTCAGACCTCCAACAACAAGACTGAGAAACTGCACAACCTCCGTATCTCCCACATAACTGCCTCAACAACCGGTTTCATCTGTCCgtctttttatttgatttcatttctgtccgaatgatgatgatgatgatgatgatgatgatgtttgtCTTGGGTCTTGTTTACTAGAGCGGGTCCGCTAAATTAGAACTGTGAGC

Function

symbol description
irs4a Predicted to enable insulin receptor binding activity and phosphatidylinositol 3-kinase binding activity. Predicted to be involved in insulin receptor signaling pathway. Predicted to be active in cytosol and plasma membrane. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 9. Orthologous to human IRS4 (insulin receptor substrate 4).

GO:

id name namespace
GO:0008286 insulin receptor signaling pathway biological_process
GO:0005829 cytosol cellular_component
GO:0005886 plasma membrane cellular_component
GO:0043548 phosphatidylinositol 3-kinase binding molecular_function
GO:0005158 insulin receptor binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-120215-92 Predicted to enable insulin receptor binding activity and phosphatidylinositol 3-kinase binding activity. Predicted to be involved in insulin receptor signaling pathway. Predicted to be active in cytosol and plasma membrane. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 9. Orthologous to human IRS4 (insulin receptor substrate 4).

Ensembl:

ensembl_id ENSDARG00000086551

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00039068 True 3442 mRNA 0.56 2 43515673 43527198

Neighbor

gene id symbol gene type direction distance location
XLOC_019856 ankrd46a coding downstream 30322 43475746 ~ 43485351 (-)
XLOC_019855 tmem185 coding downstream 41661 43460631 ~ 43474012 (-)
XLOC_019854 stk26 coding downstream 58119 43420304 ~ 43457554 (-)
XLOC_019852 ccni2 coding downstream 117216 43379878 ~ 43398457 (-)
XLOC_019853 AL954767.1 coding downstream 122594 43390401 ~ 43393079 (-)
XLOC_019858 si:ch73-362m14.2 coding upstream 9141 43536339 ~ 43550120 (-)
XLOC_019859 si:ch73-362m14.4 coding upstream 54143 43581341 ~ 43606502 (-)
XLOC_019860 htr2cl2 coding upstream 82254 43609452 ~ 43616586 (-)
XLOC_019861 si:ch1073-263o8.2 coding upstream 103240 43630438 ~ 43636631 (-)
XLOC_019862 si:dkey-229d11.5 coding upstream 117375 43644573 ~ 43666481 (-)
XLOC_019850 NA non-coding downstream 189781 43325281 ~ 43325892 (-)
XLOC_019849 NA non-coding downstream 263849 43246707 ~ 43251824 (-)
XLOC_019840 NA non-coding downstream 1359421 42150360 ~ 42156252 (-)
XLOC_019838 NA non-coding downstream 1466868 42043974 ~ 42048805 (-)
XLOC_019864 NA non-coding upstream 157664 43684862 ~ 43700280 (-)
XLOC_019872 NA non-coding upstream 629875 44157073 ~ 44157770 (-)
XLOC_019876 CU855912.1 non-coding upstream 1040982 44568180 ~ 44568266 (-)
XLOC_019879 NA non-coding upstream 1255070 44782268 ~ 44785206 (-)
XLOC_019881 NA non-coding upstream 1594164 45121362 ~ 45123821 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000040_01418438_01423899 IRS4, IRS4A coding CI01000040 null 1418052 ~ 1423899 (-)