XLOC_019874 (brcc3)


Basic Information

Item Value
gene id XLOC_019874
gene name brcc3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007132.7
NCBI id CM002905.2
chromosome length 45934066
location 44547450 ~ 44556411 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00039094
GCGATGGCTGTCAACGCGGTGCATTTAGAGTCGGACGCGTTTCTGGTGTGTATGAACCACGCGCTGAGCACCGAGAAAGAGGAGGTGATGGGGCTCTGCATCGGAGAGGTGGACACGAACCGTATAgtgcacattcattcagtgatcATCCTGCGGCGCTCAGACAAGAGGAAAGACCGAGTGGAGATTTCACCAGAACAGCTGTCAGCAGCGTCCACCGAGGCCGAGAGGTTGGCAGAGATGACGGGACGTCCCATGAGGGTTGTGGGCTGGTACCACTCTCACCCGCACATCACAGTGTGGCCTTCGCATGTGGATGTTCGCACTCAAGCCATGTATCAGATGATGGACCAGGGCTTTGTCGGACTCATCTTCTCCTGCTTTATAgaggataaaaacacaaagACTGGTAGAGTGCTGTACACCTGCTTCCAGTCTGTACAGGCCCAGAAAGGCTCAGAGTATGAGCGGATCGAGATCCCAATCCATGTCGTTCCACATGAAGCCATTGGGAAAGTGTGTCTGGAGTCGGCAGTGgagttacccagaatcctctgtcAGGAAGAGCAGGACACGTACAGGAGGATTCACAGTTTAACTCACCTGGATCCGATCACAAAGATACATAATGGATCAGtgttCACGAAAAACCTGTGCAGTCAGATGTCGGCCATCAGCGGGCCGCTCTTACAGTGGCTGGAGGACCGACTGGAGCAGAACAAACAGAGCATCATCACACTGCAGAAGGAGAAAGAGCTGCTGACGCAAGAGCTGGCGGCATTGTAA
>TCONS_00039095
GTAGCATTTAAAAAACATagctgttttcctttttttatataataatgtccatttatattacataaataataactGATTATAAGTGTAGTTCTCCccgatcatcacacacacacaccgtcatcTCTGTTGCCATCCGCCTGTTTGTTTCCTGTCGGAAGGAATAGAATGTAGCGCACTTTTCGCGGATGTGGAAGTGTAGTAcagtaataaacaaaaacaaactaatcaAAGCAGAATATCATACATTTTATACTTTACTGTTCGCGATGGCTGTCAACGCGGTGCATTTAGAGTCGGACGCGTTTCTGGTGTGTATGAACCACGCGCTGAGCACCGAGAAAGAGGAGGTGATGGGGCTCTGCATCGGAGAGGTGGACACGAACCGTATAgtgcacattcattcagtgatcATCCTGCGGCGCTCAGACAAGAGGAAAGACCGAGTGGAGATTTCACCAGAACAGCTGTCAGCAGCGTCCACCGAGGCCGAGAtatccAGGTTGGCAGAGATGACGGGACGTCCCATGAGGGTTGTGGGCTGGTACCACTCTCACCCGCACATCACAGTGTGGCCTTCGCATGTGGATGTTCGCACTCAAGCCATGTATCAGATGATGGACCAGGGCTTTGTCGGACTCATCTTCTCCTGCTTTATAgaggataaaaacacaaagACTGGTAGAGTGCTGTACACCTGCTTCCAGTCTGTACAGGCCCAGAAAGGCTCAGAGTATGAGCGGATCGAGATCCCAATCCATGTCGTTCCACATGAAGCCATTGGGAAAGTGTGTCTGGAGTCGGCAGTGgagttacccagaatcctctgtcAGGAAGAGCAGGACACGTACAGGAGGATTCACAGTTTAACTCACCTGGATCCGATCACAAAGATACATAATGGATCAGgtaaaataaacaaaaattcatGCAGGCCAGATTGATCGTCAGGCCACCGGAAAATGTCCCGGTGTtccctatggccagtccacccctgagtctaatgttctgatgagttgattcaggtgtgtttgaacagtccaggggtgtccacactccggcctggagggccagtgtcctggagattttagctccaaccctaatgaaacacacctgaagcagctaatcaagctcttactaggtatacttgaaacacacaggcaggtgtgttgtcGCAAGtgggagctaaactcagcaggacaccggccctccatgaccaagtttggacacccgcTTGAAAATGTgtgctgttggtgtgccttcaggaacaaaCTTGGGAAATACCGAGTCCATGGTCTGCTAATAGCAtgcattgtacattaaaataaagcgtgacattta

Function

symbol description
brcc3 Predicted to enable metallopeptidase activity; polyubiquitin modification-dependent protein binding activity; and thiol-dependent deubiquitinase. Acts upstream of or within angiogenesis. Predicted to be located in cytoplasm; nucleus; and spindle pole. Predicted to be part of BRCA1-A complex and BRISC complex. Is expressed in axial vasculature and head. Orthologous to human BRCC3 (BRCA1/BRCA2-containing complex subunit 3).

GO:

id name namespace
GO:0006302 double-strand break repair biological_process
GO:0070536 protein K63-linked deubiquitination biological_process
GO:0070537 histone H2A K63-linked deubiquitination biological_process
GO:0001525 angiogenesis biological_process
GO:0006281 DNA repair biological_process
GO:0070531 BRCA1-A complex cellular_component
GO:0070552 BRISC complex cellular_component
GO:0004843 thiol-dependent ubiquitin-specific protease activity molecular_function
GO:0031593 polyubiquitin modification-dependent protein binding molecular_function
GO:0008237 metallopeptidase activity molecular_function

KEGG:

id description
ko03440 Homologous recombination
ko04621 NOD-like receptor signaling pathway
ko01002 Peptidases and inhibitors
ko04121 Ubiquitin system
ko03036 Chromosome and associated proteins
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-100215-1 Predicted to enable metallopeptidase activity; polyubiquitin modification-dependent protein binding activity; and thiol-dependent deubiquitinase. Acts upstream of or within angiogenesis. Predicted to be located in cytoplasm; nucleus; and spindle pole. Predicted to be part of BRCA1-A complex and BRISC complex. Is expressed in axial vasculature and head. Orthologous to human BRCC3 (BRCA1/BRCA2-containing complex subunit 3).

Ensembl:

ensembl_id ENSDARG00000098242

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00039094 False 786 mRNA 0.53 8 44547450 44556148
TCONS_00039095 True 1338 mRNA 0.47 8 44547631 44556411

Neighbor

gene id symbol gene type direction distance location
XLOC_019873 zgc:136410 coding downstream 34557 44505613 ~ 44512893 (-)
XLOC_019872 NA coding downstream 389680 44157073 ~ 44157770 (-)
XLOC_019871 oatx coding downstream 442850 44091342 ~ 44104600 (-)
XLOC_019870 FO704810.1 coding downstream 465910 44041088 ~ 44081540 (-)
XLOC_019869 ndufa2 coding downstream 538281 44005521 ~ 44009169 (-)
XLOC_019875 fundc2 coding upstream 1380 44557791 ~ 44565862 (-)
XLOC_019876 CU855912.1 coding upstream 11769 44568180 ~ 44568266 (-)
XLOC_019877 ammecr1 coding upstream 152869 44709280 ~ 44731865 (-)
XLOC_019878 kif4 coding upstream 178770 44735181 ~ 44772738 (-)
XLOC_019879 NA coding upstream 225857 44782268 ~ 44785206 (-)
XLOC_019864 NA non-coding downstream 847170 43684862 ~ 43700280 (-)
XLOC_019853 AL954767.1 non-coding downstream 1154371 43390401 ~ 43393079 (-)
XLOC_019850 NA non-coding downstream 1221558 43325281 ~ 43325892 (-)
XLOC_019849 NA non-coding downstream 1295626 43246707 ~ 43251824 (-)
XLOC_019881 NA non-coding upstream 564951 45121362 ~ 45123821 (-)
XLOC_019882 NA non-coding upstream 608403 45164814 ~ 45188233 (-)
XLOC_019887 NA non-coding upstream 934816 45491227 ~ 45492856 (-)

Expression


Co-expression Network