XLOC_019908 (prkar2ab)


Basic Information

Item Value
gene id XLOC_019908
gene name prkar2ab
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007133.7
NCBI id CM002906.2
chromosome length 39133080
location 110158 ~ 130695 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00039722
CTGATCTCCGCACTGAAGCCCAGCATGAGCGTGCCGGTGCCGGCGGGTCTCCCGGAGCTGCTGCGGGGTTTCACGCTGGAGGTGCTGCGGCGGCAGCCCGCGGACCTGCTGGAGTTCAGCGTACGGTATTTCACCGGCCTGCGGGACACACGGAGCTCCACCCGGTCCGCTAGCAGCCGCTCTCCGGTGACCCGCGGGGAGGCCTTCGACCGGGACTCCGCACACACCGACTCCAGCGTCGAGGAGGAGGAGAAAccggaggaagaagaggaggaggaggagaaaccggaggaggaggatgaagaggaggaCGACTTCCCTGATGATTTCACTTTTAAAGctcCTCCTCCCAGTAAGTGCAACAGGCGGGTGTCAGTGTGTGCGGAACCCTATAACcctgatgaggatgatgatgatggtgatgaaggCTCGCAGCTGACCGTGCTGCACCAGAAGACGGATGAGCAGCGGCAGCGGCTGCAGGACGCCTGCAAACACATCCTGCTGTTCAAGACCCTGGAGGAGgATCAGCTGGCGGAGGTGTTAGACAGCATGTTTGAGGTGTTGGTCAAACCTGGCGAGTGCATCATCAATCAGGGTGACGACGGGGATAATTTCTACGTCATCGAGAGgggTGTGTATGAGATCGTGATCCAGCAGGATGGGCTCCAGCACTCAGTCGGCCGCTATGATCATAAAGGCAGTTTTGGAGAGCTAGCGCTGATGTACAACACGCCGCGCGCCGCCACCATCAGGGCGCTCCAGGAGGGGGCACTGTGGGCACTGgacaGAGCCACGTTCCACAGACTCATCGTGAAGAATAATGCTAAGAAGAGGAGGATGTACGAGAGCTTCATTGAGTGTGTGCCGCTGCTGAAGtctctgcagctgtcGGAGCGTATGAAGATCGTGGATGTTCTGGGCATGAGGAGCTTCAGTGACGGCGAGCGCATCATTCAGCAGGGGGATTCTGCTGACTGCTTCTACATCGTGGAGTCTGGAGAGGTGCGGATCATGATCAGGAGTAAGacccGTGCTTGTCAGCTCCTGCAGGAGGAGGTGGAGGTGGCTCGCTGCTCCAGAGGACAGTATTTTGGAGAGCTGGCGCTGGTCACCAAGAGGCCCAGAGCTGCATCTGTGTATGCTGTTGGAGACACCAGGTGTTTGGtgataGACGTGCAGGCCTTCGAGCGTCTGCTGGGCTCCTGTAAGCAGATCCTCAAGAGGAACATCACACACTACGAGCAGCAGCTGGTGGCGGTGTTCGGATCCAGCGTCGACCtcaaacactgacacacacacacacacacacacacacctcaaaaatatatataaagtgtgtgtgttaaCGGCAAAACTATCGGTCCTCCTGTTTTCCTCCAGATACTCCCAGAGTGCCGTTGGGCAGGGGGGAGATGTGGTCAGTGTATTTGCAGCTCTTCTTCATTAAGGTCTGAGTGAagcttcagttcagttcagttcagttcagcagTGTTACAGCAGCTCAGTGAACTGACCCCACAGCACCCTCCACTCCAACATCAGCCCGGCCAAACACATCACtgaccagacacacacacgcaacaCCATGACATGTGCTGTTCAACTGCCTAtgagcacgcacgcacgcacacacacacacacacacagctgaactcAAGAGTGTATTTATGTGCAGCTCAGCATGAGAATGTTTGATGAAtctgtctgacacacacacacacacgcgcgtgcgcgcacacacacacacacacgcgcgcgcgcacgcacacacgcacgcacacacacacacacacagcaggatgTGTAACAGGTTTAGAAGTGTGCACTGTAGAGtgtgctgtaaatgctgctctagtatcttctgcacacacacacacacacatacacatacacagataGATTCTCCCCCTgctgatgttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtggtcaataAAGTCTGGAATAAGG

Function

symbol description
prkar2ab Predicted to enable cAMP binding activity; cAMP-dependent protein kinase inhibitor activity; and protein kinase A catalytic subunit binding activity. Predicted to be involved in negative regulation of cAMP-dependent protein kinase activity. Predicted to act upstream of or within regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be part of cAMP-dependent protein kinase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha).

GO:

id name namespace
GO:0043949 regulation of cAMP-mediated signaling biological_process
GO:0010738 regulation of protein kinase A signaling biological_process
GO:0001932 regulation of protein phosphorylation biological_process
GO:0005952 cAMP-dependent protein kinase complex cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0030552 cAMP binding molecular_function
GO:0008603 cAMP-dependent protein kinase regulator activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-2427 Predicted to enable cAMP binding activity; cAMP-dependent protein kinase inhibitor activity; and protein kinase A catalytic subunit binding activity. Predicted to be involved in negative regulation of cAMP-dependent protein kinase activity. Predicted to act upstream of or within regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be part of cAMP-dependent protein kinase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha).

Ensembl:

ensembl_id ENSDARG00000009477

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00039722 True 1979 mRNA 0.56 10 110158 130695

Neighbor

gene id symbol gene type direction distance location
XLOC_019907 slc25a20 coding upstream 472 105376 ~ 109686 (+)
XLOC_019906 nckipsd coding upstream 7893 94692 ~ 102265 (+)
XLOC_019905 zgc:112334 coding upstream 20171 81799 ~ 89987 (+)
XLOC_019904 CABZ01085137.1 coding upstream 25735 60264 ~ 84423 (+)
XLOC_019902 NA coding upstream 49790 51545 ~ 60368 (+)
XLOC_019909 NA coding downstream 88472 219167 ~ 287189 (+)
XLOC_019910 NA coding downstream 109473 240168 ~ 309204 (+)
XLOC_019911 btg2 coding downstream 205561 336256 ~ 339623 (+)
XLOC_019912 CU914780.1 coding downstream 214068 344763 ~ 355286 (+)
XLOC_019913 ora4 coding downstream 243783 374478 ~ 378236 (+)
XLOC_019903 NA non-coding upstream 53418 53914 ~ 56740 (+)
XLOC_019901 NA non-coding upstream 82314 24421 ~ 27844 (+)
XLOC_019924 NA non-coding downstream 680905 811600 ~ 817627 (+)
XLOC_019927 NA non-coding downstream 792816 923511 ~ 938827 (+)
XLOC_019938 CU570769.1 non-coding downstream 1119093 1249788 ~ 1267820 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location