gba (gba)


Basic Information

Item Value
gene id gba
gene name gba
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048566.1
NCBI id CM023220.2
chromosome length 103806877
location 17506575 ~ 17515027 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_036939779.1
GGGCCAGTCAGTTTGAGTAGTGCCTGTGTACGTTGGGTCCGGGTTGGTGGATGTTGGTGGGCACTATATTCATCCAAATACACTTCAACTTGATTATTTCATGGAAAATGATCGTCCCGAACTGTTTGTGCTAGTTAACTAGCTACGTGAGTTTCAGTGGCTTTGCAGGCTCGTTACACATTGGTTACACTACTATGGTGGGCAGTGTTCCCAACCTTGTATTTGTCACTGGCGACCTCTAGCGGTAAACTACAATTTACATTGAAGTGACGTACCATAGTGCGCTTGTCATATGACTATCGAGGTCCATACAATTTTGAACAATCCGGAAATAGCAGAGAAAATCAGTTGGACATGCGACTCAATATTTGACGTGCACTTTATGTCAAAGATCCTGATAAAAACTAGAATGCCATTGTCAACAGCACTCATCCCTCTCGCTTTGTTCATTGGAGTAGCAACACGATCCAGAGGCAGTGATGAGTGTGTGGCCCGTAACTTTGGCCATGGCTCGGTGGTGTGTGAGTGTAACTCCACCCACTGTGACAGTATTGGGTCGGGCACACTGCCTGCACTGGGTCAGTTCCTGTCCTTCACCAGCAGTAAGGCTGGCAGCAGGCTgcagagaggacagggacagGTACAGAAGAACAGCACTGGAGCAGttCTCAGGCTGACTGTGGTTCCCTACCAGAAGTACCAGAGGATCAGAGGGTTTGGAGGAGCCATGTCAGACTCCGCTGCCATCAAcatcctgtctctgtcccccagAACACAGGACCAGCTACTACGACAGTACTTCTCTGCTCAGGGTATTGGGTACAGTGTGGTGCGGGTGCCCATTGCCAGCTGTGACTTCTCAACCCATCTGTACACCTACGCTGACTCACCTGGCGACTACAACCTGGACAACTTTACCTTATCACCAGAGGACACGAACATGAAGATCCCACTGCTGCAGCGAGCCCAGGCCCTGTCGCCCCGCCCCCTGTCTCTGCTGGCCAGTGCCTGGAGCGCCCCCGCATGGTTGAAGACCAACGGTGCTCTCACTGGCAAGGGCTCTCTGAAGGGCCAGCCTGGGGGCAAGGAGCACAAGACCTGGGCTAAATACTATGTCAGGTTCCTGGAGGAGTATGCCAAATACAACCTATCATTCTGGGCCGTGACCACAGGCAACGAGCCCTCTGCTGGACAGATGACCAACTACAGTTTCCAGGCTCTGGGCTTCACAGCAGAGGAGCAGAGGGATTGGGTGGGCCTGGACCTTGGCCCCGCCCTACACACctccacacacccccacacacacctcctcatccTGGACGACAACAGACTGCTACTGCCACACTGGGCTAAAGTGgtcctcagtgatgtgcgTGCTGGCAGGTATATCCATGGTGTTGGAGTCCACTGGTACCTGGACACCCTGGTGCCGGCAGAGCTCTCCCTGGGCACTACCCACCACCTGTACCCAGAATACTACCTGTTTGGAACGGAGGCCTGCGCTGGCTGGAGCCCCTCAGACAGAGGAGTACGGCTGGGCAGCTGGGAGAGAGCTGAGCAGTACGCACACAGCATCATACAGGACCTGAACCACTATGTGGTGGGCTGGACAGACTGGAACCTGGCTCTGGACCAAGGAGGAGGGCCCAACTGGGTGAAGAACTTTGTGGACAGCCCTATCATCGTGGACCACAGCCGAGACATCTTCTACAAACagcccaccttctatagcatggcccacttcagTAAGTTcctgtgggaggggtctcagaGAGTGGGTGTGTCCTTCAGTCAGGAAACAAAACTGGAAAGCTCTGCCTTCGTCAGGCCAGACGGGTCAGTGGTGCTTACCATCCTCAACAGgttgtCGTCAGAGGTCCAGTTTGAGGTGTATGATCCTGCTGTGGGTTTCATCTCCTCCAGTGCTCCAGCCCACTCCCTGCTCACACTCGCTTGGAACACACTCTGACCGCACTGGAATGGAACACACACCTTTACTGCCAGGGCCAAAGCATTGTCACAGTCCTCACTACCAGGTCTGCTACATTTCCACCACTACACACTCAACTCCCACCACCATCCGAAGCCCAATGTGCTGCCTCCTCAGAACAGCATATCTAATAGATAACCTGCAGCATCGTGGGCTCTGGCATTTCTGGGATCAGAgcttgaaatgtgtgtgtgttttagccaaTACAGCCAAATATGTTGCGTGTTCCTATGCTGTGACTATCTGCACTGATCTTTATCACGCTGGGAGAAGCTCTGGAATGTGTGAATATAGCATGTGATCAAACCAGGACCAGGTACACTATCTACTATGATCAGACACTGCTGCTGCTTGAGACGGTCTGACCATTACACTGCTAACAACCGTTTCTAAACTGAAATCTGGTTTAGAAAAGAGATCATGTACCGAATCTATTAATGCCGTTTAAACCATTTGCCTTTTGAATAAATGATGTCTCTCTA
>XM_036939785.1
GGCCAGTCAGTTTGAGTAGTGCCTGTGTACGTTGGGTCCGGGTTGGTGGATGTTGGTGGGCACTATATTCATCCAAATACACTTCAACTTGATTATTTCATGGAAAATGATCGTCCCGAACTGTTTGTGCTAGTTAACTAGCTACGTGAGTTTCAGTGGCTTTGCAGGCTCGTTACACATTGGTTACACTACTATGGTGGGCAGTGTTCCCAACCTTGTATTTGTCACTGGCGACCTCTAGCGGTAAACTACAATTTACATTGAAGTGACGTACCATAGTGCGCTTGTCATATGACTATCGAGGTCCATACAATTTTGAACAATCCGGAAATAGCAGAGAAAATCAGTTGGACATGCGACTCAATATTTGACGTGCACTTTATGTCAAAGATCCTGATAAAAACTAGATAGAATGCCATTGTCAACAGCACTCATCCCTCTCGCTTTGTTCATTGGAGTAGCAACACGATCCAGAGGCAGTGATGAGTGTGTGGCCCGTAACTTTGGCCATGGCTCGGTGGTGTGTGAGTGTAACTCCACCCACTGTGACAGTATTGGGTCGGGCACACTGCCTGCACTGGGTCAGTTCCTGTCCTTCACCAGCAGTAAGGCTGGCAGCAGGCTgcagagaggacagggacagGTACAGAAGAACAGCACTGGAGCAGttCTCAGGCTGACTGTGGTTCCCTACCAGAAGTACCAGAGGATCAGAGGGTTTGGAGGAGCCATGTCAGACTCCGCTGCCATCAAcatcctgtctctgtcccccagAACACAGGACCAGCTACTACGACAGTACTTCTCTGCTCAGGGTATTGGGTACAGTGTGGTGCGGGTGCCCATTGCCAGCTGTGACTTCTCAACCCATCTGTACACCTACGCTGACTCACCTGGCGACTACAACCTGGACAACTTTACCTTATCACCAGAGGACACGAACATGAAGATCCCACTGCTGCAGCGAGCCCAGGCCCTGTCGCCCCGCCCCCTGTCTCTGCTGGCCAGTGCCTGGAGCGCCCCCGCATGGTTGAAGACCAACGGTGCTCTCACTGGCAAGGGCTCTCTGAAGGGCCAGCCTGGGGGCAAGGAGCACAAGACCTGGGCTAAATACTATGTCAGGTTCCTGGAGGAGTATGCCAAATACAACCTATCATTCTGGGCCGTGACCACAGGCAACGAGCCCTCTGCTGGACAGATGACCAACTACAGTTTCCAGGCTCTGGGCTTCACAGCAGAGGAGCAGAGGGATTGGGTGGGCCTGGACCTTGGCCCCGCCCTACACACctccacacacccccacacacacctcctcatccTGGACGACAACAGACTGCTACTGCCACACTGGGCTAAAGTGgtcctcagtgatgtgcgTGCTGGCAGGTATATCCATGGTGTTGGAGTCCACTGGTACCTGGACACCCTGGTGCCGGCAGAGCTCTCCCTGGGCACTACCCACCACCTGTACCCAGAATACTACCTGTTTGGAACGGAGGCCTGCGCTGGCTGGAGCCCCTCAGACAGAGGAGTACGGCTGGGCAGCTGGGAGAGAGCTGAGCAGTACGCACACAGCATCATACAGGACCTGAACCACTATGTGGTGGGCTGGACAGACTGGAACCTGGCTCTGGACCAAGGAGGAGGGCCCAACTGGGTGAAGAACTTTGTGGACAGCCCTATCATCGTGGACCACAGCCGAGACATCTTCTACAAACagcccaccttctatagcatggcccacttcagTAAGTTcctgtgggaggggtctcagaGAGTGGGTGTGTCCTTCAGTCAGGAAACAAAACTGGAAAGCTCTGCCTTCGTCAGGCCAGACGGGTCAGTGGTGCTTACCATCCTCAACAGgttgtCGTCAGAGGTCCAGTTTGAGGTGTATGATCCTGCTGTGGGTTTCATCTCCTCCAGTGCTCCAGCCCACTCCCTGCTCACACTCGCTTGGAACACACTCTGACCGCACTGGAATGGAACACACACCTTTACTGCCAGGGCCAAAGCATTGTCACAGTCCTCACTACCAGGTCTGCTACATTTCCACCACTACACACTCAACTCCCACCACCATCCGAAGCCCAATGTGCTGCCTCCTCAGAACAGCATATCTAATAGATAACCTGCAGCATCGTGGGCTCTGGCATTTCTGGGATCAGAgcttgaaatgtgtgtgtgttttagccaaTACAGCCAAATATGTTGCGTGTTCCTATGCTGTGACTATCTGCACTGATCTTTATCACGCTGGGAGAAGCTCTGGAATGTGTGAATATAGCATGTGATCAAACCAGGACCAGGTACACTATCTACTATGATCAGACACTGCTGCTGCTTGAGACGGTCTGACCATTACACTGCTAACAACCGTTTCTAAACTGAAATCTGGTTTAGAAAAGAGATCATGTACCGAATCTATTAATGCCGTTTAAACCATTTGCCTTTTGAATAAATGATGTCTCTCTA

Function

symbol description
gba Enables glucosylceramidase activity. Acts upstream of or within neuron cellular homeostasis; regulation of ossification; and swimming. Predicted to be located in lysosomal membrane. Is expressed in brain; fin; and liver. Used to study Gaucher's disease. Human ortholog(s) of this gene implicated in Gaucher's disease (multiple); Lewy body dementia; Parkinson's disease (multiple); and Parkinsonism. Orthologous to human GBA (glucosylceramidase beta).

NR:

description
glucosylceramidase isoform X1

GO:

id name namespace
GO:0006665 sphingolipid metabolic process biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0004348 glucosylceramidase activity molecular_function

KEGG:

id description
K01201 GBA, srfJ; glucosylceramidase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_036939779.1 False 2472 mRNA 0.52 12 17506575 17515027
XM_036939785.1 True 2475 mRNA 0.52 12 17506576 17515027

Neighbor

gene id symbol gene type direction distance location
dap3 LOC106605893 coding upstream 10607 17484825 ~ 17495968 (+)
rusc1 LOC106605889 coding upstream 54089 17426432 ~ 17452486 (+)
fdps LOC106605924 coding upstream 80579 17422056 ~ 17425996 (+)
LOC110520798 fam189b coding upstream 92686 17395343 ~ 17421816 (+)
LOC110520882 rab13 coding upstream 111785 17383063 ~ 17394790 (+)
polr3c LOC106605790 coding downstream 8057 17523084 ~ 17532237 (+)
LOC110536418 LOC106575022 coding downstream 501768 18016795 ~ 18047915 (+)
LOC110536431 LOC107573682 coding downstream 537478 18052505 ~ 18071232 (+)
trim108 LOC106573777 coding downstream 561944 18076971 ~ 18086938 (+)
LOC110536448 NA coding downstream 575281 18090308 ~ 18094143 (+)
G117865 NA non-coding upstream 5371 17500646 ~ 17501204 (+)
G117864 NA non-coding upstream 6345 17499938 ~ 17500230 (+)
G117842 NA non-coding upstream 62963 17442891 ~ 17443612 (+)
G117839 NA non-coding upstream 98777 17406203 ~ 17407798 (+)
G117883 NA non-coding downstream 21493 17536520 ~ 17543637 (+)
G117943 NA non-coding downstream 145757 17660784 ~ 17661055 (+)
G117926 NA non-coding downstream 168660 17683687 ~ 17686455 (+)
G117959 NA non-coding downstream 207734 17722761 ~ 17723043 (+)
G117960 NA non-coding downstream 208217 17723244 ~ 17723459 (+)
G117735 NA other upstream 48553 17455765 ~ 17458022 (+)
G117714 LOC106605886 other upstream 432874 17073201 ~ 17073701 (+)
G117704 NA other upstream 455736 17050132 ~ 17050839 (+)
LOC110536275 s10i other upstream 508214 16995630 ~ 16998361 (+)
LOC110536658 LOC106577300 other downstream 942331 18457284 ~ 18481741 (+)
G119153 LOC106605761 other downstream 1118812 18633839 ~ 18636041 (+)
G119160 NA other downstream 1155486 18670513 ~ 18672320 (+)
G119245 stl2 other downstream 1444109 18934673 ~ 18992769 (+)
LOC110503718 LOC102193556 other downstream 1741559 19131905 ~ 19259074 (+)

Expression


Co-expression Network