Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_020669 |
| gene name | cdkn1a |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007133.7 |
| NCBI id | CM002906.2 |
| chromosome length | 39133080 |
| location | 603382 ~ 607812 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| cdkn1a | Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and kinase activity. Acts upstream of or within aorta development; response to X-ray; and skeletal muscle cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; hatching gland; male organism; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in high grade glioma; ocular hypertension; oral mucosa leukoplakia; oral squamous cell carcinoma; and primary open angle glaucoma. Orthologous to human CDKN1A (cyclin dependent kinase inhibitor 1A). |
| id | name | namespace |
|---|---|---|
| GO:0072331 | signal transduction by p53 class mediator | biological_process |
| GO:0007519 | skeletal muscle tissue development | biological_process |
| GO:0010165 | response to X-ray | biological_process |
| GO:0007050 | cell cycle arrest | biological_process |
| GO:0035904 | aorta development | biological_process |
| GO:0007346 | regulation of mitotic cell cycle | biological_process |
| GO:0035914 | skeletal muscle cell differentiation | biological_process |
| GO:0016310 | phosphorylation | biological_process |
| GO:0005634 | nucleus | cellular_component |
| GO:0016740 | transferase activity | molecular_function |
| GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity | molecular_function |
| GO:0016301 | kinase activity | molecular_function |
| id | description |
|---|---|
| ko04012 | ErbB signaling pathway |
| ko04630 | JAK-STAT signaling pathway |
| ko04066 | HIF-1 signaling pathway |
| ko04068 | FoxO signaling pathway |
| ko04151 | PI3K-Akt signaling pathway |
| ko04110 | Cell cycle |
| ko04115 | p53 signaling pathway |
| ko04218 | Cellular senescence |
| ko04921 | Oxytocin signaling pathway |
| ko04928 | Parathyroid hormone synthesis, secretion and action |
| ko05200 | Pathways in cancer |
| ko05202 | Transcriptional misregulation in cancer |
| ko05206 | MicroRNAs in cancer |
| ko05205 | Proteoglycans in cancer |
| ko05203 | Viral carcinogenesis |
| ko05210 | Colorectal cancer |
| ko05212 | Pancreatic cancer |
| ko05225 | Hepatocellular carcinoma |
| ko05226 | Gastric cancer |
| ko05214 | Glioma |
| ko05216 | Thyroid cancer |
| ko05220 | Chronic myeloid leukemia |
| ko05217 | Basal cell carcinoma |
| ko05218 | Melanoma |
| ko05211 | Renal cell carcinoma |
| ko05219 | Bladder cancer |
| ko05215 | Prostate cancer |
| ko05213 | Endometrial cancer |
| ko05224 | Breast cancer |
| ko05222 | Small cell lung cancer |
| ko05223 | Non-small cell lung cancer |
| ko05166 | Human T-cell leukemia virus 1 infection |
| ko05161 | Hepatitis B |
| ko05160 | Hepatitis C |
| ko05163 | Human cytomegalovirus infection |
| ko05167 | Kaposi sarcoma-associated herpesvirus infection |
| ko05169 | Epstein-Barr virus infection |
| ko05165 | Human papillomavirus infection |
| ko04934 | Cushing syndrome |
| ko01524 | Platinum drug resistance |
| ko01522 | Endocrine resistance |
| id | description |
|---|---|
| ZDB-GENE-070705-7 | Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and kinase activity. Acts upstream of or within aorta development; response to X-ray; and skeletal muscle cell differentiation. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; hatching gland; male organism; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in high grade glioma; ocular hypertension; oral mucosa leukoplakia; oral squamous cell carcinoma; and primary open angle glaucoma. Orthologous to human CDKN1A (cyclin dependent kinase inhibitor 1A). |
| ensembl_id | ENSDARG00000076554 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00040870 | False | 1029 | mRNA | 0.49 | 3 | 603382 | 606067 |
| TCONS_00040871 | True | 834 | mRNA | 0.54 | 3 | 603719 | 607812 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_020668 | tmcc2 | coding | downstream | 3366 | 591809 ~ 600016 (-) |
| XLOC_020667 | bysl | coding | downstream | 45417 | 550828 ~ 557965 (-) |
| XLOC_020666 | ccnd3 | coding | downstream | 55622 | 537717 ~ 547760 (-) |
| XLOC_020665 | dstyk | coding | downstream | 96860 | 472327 ~ 506522 (-) |
| XLOC_020664 | NA | coding | downstream | 207482 | 392619 ~ 395900 (-) |
| XLOC_020670 | srsf3b | coding | upstream | 5453 | 613265 ~ 622967 (-) |
| XLOC_020671 | apobec2a | coding | upstream | 33530 | 641342 ~ 651719 (-) |
| XLOC_020672 | NA | coding | upstream | 52105 | 659917 ~ 697504 (-) |
| XLOC_020673 | NA | coding | upstream | 92401 | 700213 ~ 704907 (-) |
| XLOC_020674 | arl8a | coding | upstream | 102947 | 710759 ~ 718615 (-) |
| XLOC_020657 | NA | non-coding | downstream | 288002 | 313710 ~ 315380 (-) |
| XLOC_020646 | NA | non-coding | downstream | 501935 | 101082 ~ 101447 (-) |
| XLOC_020641 | NA | non-coding | downstream | 567266 | 27146 ~ 36116 (-) |
| XLOC_020675 | NA | non-coding | upstream | 125432 | 733244 ~ 735244 (-) |
| XLOC_020676 | NA | non-coding | upstream | 131488 | 739300 ~ 760886 (-) |
| XLOC_020684 | NA | non-coding | upstream | 410533 | 1018345 ~ 1023531 (-) |
