aars1 (aars)


Basic Information

Item Value
gene id aars1
gene name aars
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048566.1
NCBI id CM023220.2
chromosome length 103806877
location 69096742 ~ 69111871 (-)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_021569882.2
CATTTTGATTGTGCCAGCGTGGGGTGTCAGTGCGAGAGGTGACAGaaataaaataaagataaactTTTCCTTTCAGAATGGACTCTTTGCTGCCTGCTGCTCAGATCCGGGAGAAGTTCATCGACTTCTTCCGTTGCCATGAACACCAGTATGTCCACTCATCCGCCACCATACCTTTGGATGACCCCACACTGCTCTTCGCTAATGCTGGCATGAACCAGTTCAAACCTATCTTCCTGAACACCATTGATCCGTCCCACCCCATGGCCAGACTCAAGCGTGCAGCTAACACACAGAAGTGCATCCGCGCTGGGGGCAAGCACAATGACCTGGATGATGTGGGCAAGGACGTGTACCACCACACCTTCTTTGAGATGCTGGGCTCCTGGTCCTTCGGAGACTACTTTAAACACCTTGCTTGTACGATGGCCCTGGAGCTGCTGACTAAGGAATTTGGGATTCCTATCGAGCGTCTGTACGTAACCTACTTCGGGGGTCATGAAGAAGCTGGGCTGGATCCAGATCTGGAGTGTAAACAGATATGGCTGGACCTCGGAATGGACGAGGCTCGTATTATACCCGGCAGCATGAAGGATAACTTCTGGGAGATGGGGGACACAGGTCCTTGTGGGCCCTGCAGTGAGATCCACTTTGACCGCATCGGGGGGAGAGATGCAGCCCACCTGGTCAATATGGACGACCCCAATGTGCTGGAGATTTGGAACCTGGTGTTCATCCAGTACAACAGGGAGTCTGAGACAGAGCTGAAGCCCCTGCCTAAGAAGAGCATTGATACAGGCATGGGTCTGGAGCGTCTGGTCTCTGTGCTGCAGAATAAGATGTCCAACTACGACACAGACCTTTTCATCCCCTACTTCCAGGCCATCCAGAAGGGTACAGGAGCCAGGGACTACACAGGAAAGGTTGGTGTTGAGGACGTAGATGGCATTGACATGGCCTACCGTGTCCTGGCTGACCACGCCCGCACCATCACCATCGCCCTCTCTGACGGTGGCAGGCCAGACAACACAGGAAGAGGATATGTGTTGAGGAGGATCCTGCGTCGTGCTGTGAGGTACTCTCACGAGAAGCTGGGTGCTCAAAAAGGCTTCTTTGCTACCCTAGTTGACGTGGTGGTAGAGTCCCTGGGCGATGCCTTCCCTGAGTTGAAGAAAGACCCAGACATGGTAAAGGACATCATCAACGAGGAAGAGGAGCAGTTCCTCAAGACACTCAGCAGGGGGCGAAAGATCCTGGACAGAAAGATCCAGAGTCTGGGAGACAGCAAGACCATCCCTGGTGACACCGCCTGGTTGCTGTATGACACATACGGTTTCCCCCTGGATCTCACTGCCCTAATTgctgaggagagggggatgatggTGGATGTTGCTGCTtttgaggaggagaagaaggctGCCCAGGTTAAGTCCCAGGGGAAGGGCTCTGGGGATGAGGACCACATCATGCTGGACATCTATGCCATCGAGGACCTTCGCAACAAAGGCATCGCTGCTACTGACGACGTACTCAAGTACAGCTACAGTGCTGACGACAGCGGCAAATATGTGTTTGAGCAGGCTGTGAGCACGGTGCTGGCTCTGAGGAGGGAGCGTGCCTTTGTGGATGAGGTGACGACAGGGCAGGAGTGTGGGGTTCTGCTGGACAAGACTTCGTTCTATGCGGAGCAGGGAGGACAGAGCTTCGACGAGGGCTACATGCTGAGAGAGGACGACTCTGTAGATGATAGGATGGAGTTCACAGTGAAGAACACTCAGGTTCGGGGTGGATACGTGCTGCATGTAGGGACGGTTTACGGCACTCTGAAGGTTGGAGATAACGTCATTCTGCATGTGGATGAGGCTCGTCGTAGGCCCATCATGAGTAACCACACTGCCACCCACATCCTGAACTTTGCCCTGAGGGAGGTCTTGGGAGAGGCTGACCAGCGTGGCTCCCTGGTGGCTCCTGACCGCCTGCGCTTTGACTTCACCGCCAAAGGTGCTCTGAGCACAGAAGAGGTGCGACGCACAGAGGAGATTGCCTGCACAATGATCCGCGATGCAAAGccTGTCTATGCCATGGATACCCCCCTGGCAGCAGCTAAAGCCATTCAGGGTCTGCGTGCTGTGTTTGATGAGACCTACCCTGACCCGGTGCGCGTGGTGTCCATTGGCATCCCCGTGGCTGACCTCCTGGCTGACCCCAGCAGCACTGCCGGCTCCTGCACCTCCATCGAGTTCTGCGGAGGAACGCACTTGCGGAACTCTGGCCATGCTGCACCTTTTGTCATCGTGTCAGAGGAGGCCATCGCCAAGGGAATCCGCCGTATCGTCGCAGTGACAGGAGCAGAAGCACAGAAGGCCCACAGGAAAGCAGATGCTCTGAGACAGTCTCTGTCTGCTCTGGGGGACAAGGTGAAGGTTCAGACCGCCCCCAATAAAGACGTGCAGAAGGAAATCGCTGACATGACAGAGTTTCTGGGCATGGCAGTGATCTCCCAGTGGCAGAAGGATAAGATGAGGGAAGCCCTGAAGGGCTTGAAGAAGACCATGGATGACCTGGACCGCGCCAGCAAGGCTGATGTCCAGAAAAGGgTTCTTGAAaagaccaaggagatgattgACAGCAGCCCTAACCAGCCGCTGGTAGTCATGGAGATGGAAAGCGGAGCCTCTGCCAAGGCTCTGAATGAGTCTCTGAAGCTGCTGAAGACCCAGTCCCCCCAGACTGCTGCTATGCTCTTCACCGTAGACAACGATGCTGGAAAGATCATCTGTTTATGCCAGGTGCCCCAGGATGTGGCCAACCGAGGTCTGAAGGCCAGTGAGTGGGTGCAGGAGCTCTGCCCTCTGATGGATGGCAAAGGTGGTGGCAAGGATATGTCTGCCCAGGCAACTGGCAGGAACACACACTGCATAGAGGAGGCTTTGCAGATGGCCAACCAGTTTGCCCAACTTAAACTGAGTGAAAACGAATAGAGAGGAGGCTGGGGTGTGGTGAATGATTATGGGGAAAGATCCCACGATCCAACCCCACTGGAATGTTCCAGCTCTGTTCTCTGTGACTCTGAACTGGACGTTCCAGAAAATTATATAGAAACATTCACCCATCCAAAGGTTAGAAAGGGAAGCAGATACAAGAGCCCTCTTTCTCTGAAAGATGCATCTGCAATTTTAAGGAGGATGACATGGTTTTGATCCATGCACAATTTGATGGCTCCCTGCAAGATCTGTGGTCGAAGGATTAGGTGATCAAATGATTGATAGGTGTATGAAGATGCTACCCCCAACATCCTACCTGATCTGTCCTGAGGTAGATAGTAAAAGTCCtccttccatcctctcctcccactTTAACTAACGATGAAAATACTCAACGGTAAACTGCTTCAGTTCATTGCTTGTTTCTCTCTATTTCATTGGCCTCTTCCATGTCATTGTTTCACTTCCCCTCCCGGACTGTGGGGAGATGTGTTCTCTGCAGACTGTCTTTCCTGCCAGTTGTAATGTACATTCACAACAGCAACCGTGGCACCTGTCAGCGCCACTAGCTGTGTAACAGTTTTATTGTCTGTCATCTCAATATTAATGTAGTCAATTAATAATGAATTTAAATAAATGGGTGACATGACATTGTCAATTCTGTGAAATGCATTTTATTGCCACTTATGAACGTCACAACGCATTCATGCCTTGATGAATTCCATGTTGTGGAATAAAAATACTGATAACACTTGA

Function

symbol description
aars Enables Ser-tRNA(Ala) hydrolase activity; alanine-tRNA ligase activity; and translation regulator activity. Involved in alanyl-tRNA aminoacylation; regulation of cytoplasmic translational fidelity; and tRNA modification. Acts upstream of or within cerebellar Purkinje cell layer development; negative regulation of neuron apoptotic process; and neuromuscular process controlling balance. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Is expressed in several structures, including adrenal gland; alimentary system; nervous system; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2N and developmental and epileptic encephalopathy 29. Orthologous to human AARS1 (alanyl-tRNA synthetase 1).

NR:

description
alanine--tRNA ligase, cytoplasmic

GO:

id name namespace
GO:0006419 alanyl-tRNA aminoacylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0004813 alanine-tRNA ligase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0003676 nucleic acid binding molecular_function

KEGG:

id description
K01872 AARS, alaS; alanyl-tRNA synthetase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_021569882.2 True 3740 mRNA 0.52 21 69096742 69111871

Neighbor

gene id symbol gene type direction distance location
sf3b3 sf3b3 coding downstream 37344 69009850 ~ 69059398 (-)
il34 il-34 coding downstream 92843 68980410 ~ 69003899 (-)
lonp2 lonp2 coding downstream 119044 68951337 ~ 68977698 (-)
cdh13 LOC106560870 coding downstream 903849 67666186 ~ 68192893 (-)
zgc:173742 LOC106560872 coding downstream 1572951 67491429 ~ 67523791 (-)
LOC110494649 LOC106560856 coding upstream 1909 69112267 ~ 69128035 (-)
LOC110494669 arl2bp coding upstream 26745 69138616 ~ 69140982 (-)
rspry1 LOC106560854 coding upstream 29277 69141148 ~ 69166663 (-)
cpne2 LOC106560852 coding upstream 67162 69179033 ~ 69205373 (-)
nlrc5 LOC106560850 coding upstream 95552 69207423 ~ 69229555 (-)
G177154 NA non-coding downstream 117285 68978979 ~ 68979457 (-)
G176712 NA non-coding downstream 181459 68915008 ~ 68915283 (-)
G176688 NA non-coding downstream 203052 68885939 ~ 68893690 (-)
G176668 NA non-coding downstream 235291 68861177 ~ 68861451 (-)
G176664 NA non-coding downstream 240003 68856535 ~ 68856739 (-)
G177244 NA non-coding upstream 4996 69116867 ~ 69117163 (-)
G177272 NA non-coding upstream 83670 69195541 ~ 69195986 (-)
G177207 NA non-coding upstream 198640 69310511 ~ 69311709 (-)
G177315 NA non-coding upstream 207690 69319561 ~ 69319944 (-)
G174505 NA other downstream 2403892 66692408 ~ 66692850 (-)
G173696 LOC106560906 other downstream 2705976 66375226 ~ 66390766 (-)
G173675 NA other downstream 2758356 66335412 ~ 66338386 (-)
LOC110494122 LOC106560915 other downstream 2798428 66277821 ~ 66299637 (-)
G173431 NA other downstream 3174513 65921850 ~ 65922229 (-)
G177487 NA other upstream 479264 69591135 ~ 69591722 (-)
LOC110494902 LOC106560839 other upstream 581738 69648833 ~ 69767366 (-)
LOC110501848 NA other upstream 1448651 70552263 ~ 70642587 (-)
fam169b fam169b other upstream 1657287 70769140 ~ 70773282 (-)
G179215 NA other upstream 1793501 70905372 ~ 70906254 (-)

Expression


Co-expression Network