rag2 (rag2)


Basic Information

Item Value
gene id rag2
gene name rag2
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048566.1
NCBI id CM023220.2
chromosome length 103806877
location 80724360 ~ 80727535 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_021573150.2
GTATTACCAGCTCAGTCTTATTGCAGTGTAGAGAGCACACCTGCCTGTCAGCAGCAGTCACAGACAGTTAACCTCAAGATCTGTAACTCATCTGAGTTAATCGAGCTTCACAAACTCTGTCAACCACTGTCTGTCTACACAGTTTAGTACTAAAGATACACAAAGACTAGCCTAACTTATTACAACATTCCACAACACTGTTCTTCGAGACGTTCAAACAGTAACGTTAGCTACTTGAGCAGAAGCCACCTGCGGTAGCATGTCTCTGCAACCACTGACTGCAGTGAACTGTGGCAGCCTCCTGCAGCCTGGCTGCTCCCTGTTACAGCTGGATGGTGACATATTTCTGTTCGGCCAAAAAGGCTGGCCCAGGCGCTCCTGTCCTACTGGGGTCTTCGGGGTACGCCTAAAGCATGGGGAGCTCAAACTGCgacccatctccttctcaaatgACTCCTGCTATCTTCCCCCTCTGCGTTGTCCCGCCGTGACCCGCCTTGAGCCCCATGATGGACACCCAGAGGGCTACCTCATCCATGGAGGCCGAACCCCAAACAACGAGATCTCCTCCAGCCTCTACCTGCTGACTCTGGACAGCCGTGGCTGCAACCGCAAAGTGACCCTGCgctgtcaggagagagagttgGTGGGAGAGCAGCCAGGGCCCCGATACGGCCACACACTTAGCATGGTGCAGAGTCTGGGCAAGCGGGCCTGCGTTGTGTTTGGGGGCAGATCCTACATGCCGGCCGGGGAGCGGAGCACAGAGAACTGGAACAGCGTTGTGGACTGCCCTCCTCAGGTGTTCATCATCGACTTAGAATTTGGCTGCTGCTCTGCCCACACCTTACCTGAGCTCACTGACGGCCAGTCCTTCCACCTAGCTTTGGCAAGAGACGACTATGTCTACTTCCTTGGTGGCCACACTCTGTCGTCTGACTCTCGTCCTCCTCGTGTGTTCTGCCTGCGTGTGGAGCTCCTGCAGGGCAGCCCTCTGCTCTCCTGTGAGCACCTGGACACCGGCCTGTCCATCTCAAGTGCTATTGCCACCCGTGTGGGGCCCTCCCATGAGTACATTATCCTGGGTGGGTATCAGTCAGAGACCCAAAAGAGGATGGAGTGCAGCAGTGTGGTGCTGGATGACTCTGGGATCAGCATCGAGCCCAGAGAGGCCCCTCAGTGGACAGGGGAAATCAGCCACAGCCACACCTGGTTCGGAGGCAGCTTGGGTGGAGGGAGCGCTCTGATTGGGGTCCCCTCTGAGGGCAGGCCAGCCCCGCCCGAAGCACATTACTTCTACCAGGTGTGCTTCCaaaaggagggggaaggagagggtgaaGATGGGAACCAGGGCTGCAGCCAGGAGTCCACAGACTTTGAGGACTCCGCCCCTCTGGAGGACTCTGAGGAGCTGTACTTCGGCCGCGAGCCCCATGAGCTGGAGGACagcagcgagggagagggggatacgtacaatgaagaggatgaggaggatgagacCCAGACAGGCTATTGGGTCAAATGTTGCCTGGGCTGCCAGGTGGACCCCAACACTTGGGAGCCCTACTACTCCACAGAACTGCTGCGGCCAGCCATGATCTACTGCTCCAAAGGGGAGGGAGGCCACTGGGTCCATGCCCAGTGTATGGAGCTGACTGAGGGCCTGCTGGTGAGGCTCTCGCAGGGAAACGGCAAGTACTTCTGCCTGGACCACGGGGGCCTGCCCCGCCAGGAGATGACCCCGCCACGTCAGGTGCTGTCCCTGAAGAGGAGCCCCATGAAACCCCAGCACAGGAAGGGCCCAATGATGCCGAAGATGACACCCGCCAAGAAGCGCTTCTTCAGGAGGCTGTTTGAGTAATGTCTGACCATGCAGTATAGTTATACTCACTCATTGATCAACTGGTTCAAAATATGTCATTCTAATTATATGGCCTAAATGCCATATCATTGTTTGATGTGCCATTGCAGCAATTTACTGTTCTCAAACTTATAAGTAAACTGAATAATTTGTTGTGCTTGTTTTTTGATTCCTTACAGTGTTCAATATTTTATGTAATAAACTAAAGTTTTGCCAAAAAATGTATGAAACCGAATTGAATAAAAATGGAA

Function

symbol description
rag2 Enables sequence-specific DNA binding activity. Contributes to double-stranded DNA endodeoxyribonuclease activity. Acts upstream of or within immune system development and protein-DNA complex assembly. Part of DNA recombinase complex and endodeoxyribonuclease complex. Is expressed in immune system and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Omenn syndrome; combined cellular and humoral immune defects with granulomas; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Orthologous to human RAG2 (recombination activating 2).

NR:

description
V(D)J recombination-activating protein 2

GO:

id name namespace
GO:0033151 V(D)J recombination biological_process
GO:0030183 B cell differentiation biological_process
GO:0033077 T cell differentiation in thymus biological_process
GO:0005634 nucleus cellular_component
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding molecular_function
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding molecular_function
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0035064 methylated histone binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding molecular_function

KEGG:

id description
K10988 RAG2; recombination-activating protein 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_021573150.2 True 2112 mRNA 0.54 2 80724360 80727535

Neighbor

gene id symbol gene type direction distance location
LOC110497165 lrrc4c coding upstream 676178 79916922 ~ 80048182 (+)
LOC110497158 LOC106573351 coding upstream 1488451 79177028 ~ 79235909 (+)
LOC110497132 pamr1 coding upstream 1573001 79103574 ~ 79151359 (+)
LOC118944149 NA coding upstream 1792884 78931423 ~ 78931476 (+)
LOC110497055 LOC106561315 coding upstream 2144170 78578149 ~ 78580190 (+)
furinb LOC106561302 coding downstream 52524 80780059 ~ 80977313 (+)
LOC110497237 rccd1 coding downstream 263443 80988887 ~ 80994869 (+)
LOC110502143 LOC106573336 coding downstream 301806 81029341 ~ 81031876 (+)
LOC118942351 NA coding downstream 304464 81031999 ~ 81033476 (+)
LOC110497304 LOC106561285 coding downstream 321971 81049506 ~ 81055428 (+)
G191024 cssa10h11orf74 non-coding upstream 1780 80721510 ~ 80722580 (+)
G191025 cssa10h11orf74 non-coding upstream 15630 80708098 ~ 80708730 (+)
G191028 NA non-coding upstream 20033 80704097 ~ 80704327 (+)
G190986 NA non-coding upstream 75372 80648652 ~ 80648988 (+)
G190977 NA non-coding upstream 84273 80639797 ~ 80640087 (+)
G191161 NA non-coding downstream 183193 80910728 ~ 81327424 (+)
G191167 NA non-coding downstream 186765 80914300 ~ 80924722 (+)
G191402 NA non-coding downstream 607543 81335078 ~ 81335608 (+)
LOC110496993 LOC106561317 other upstream 2217428 78467699 ~ 78519071 (+)
G187320 LOC106561323 other upstream 2454315 78267289 ~ 78270045 (+)
G187260 NA other upstream 2546777 78137513 ~ 78177583 (+)
LOC110502077 LOC106561326 other upstream 2675560 78047373 ~ 78066844 (+)
G191052 NA other downstream 27606 80755141 ~ 80756647 (+)
G191057 accs other downstream 37797 80765332 ~ 80766714 (+)
LOC110497314 cfap44 other downstream 338019 81058184 ~ 81080502 (+)
LOC110497320 paf other downstream 356293 81083756 ~ 81086188 (+)
LOC110497665 LOC106561427 other downstream 1638750 82366183 ~ 82393779 (+)

Expression


Co-expression Network