XLOC_020739 (pak2b)


Basic Information

Item Value
gene id XLOC_020739
gene name pak2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007133.7
NCBI id CM002906.2
chromosome length 39133080
location 2895511 ~ 2929156 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00040903
ATGTGTGATAATGGCGATGTGGAGGACAAGCCGCCCGCTCCGCCTGTCAGGATGAGCAGCACCATCTTCAGCGGCGCCAAAGACCACGCCCTCACCGCCAATCACAGCTCCAAGCCCCTCCCATCGGTCCCAGAGGAGCGCAAGCGCAACAAGATCTACTCCATCTTCTCCGGCGCAGAGAAAGgtggaCGCAGGAAGGATCGTGATAAAGAGCGTCCTGAAATCTCTCCACCGTCAGACTTCGAGCACACCATTCATGTGGGATTTGACGCCGTTACTGGAGAGTTCACTGGAATGCCGGAGCAGTGGGCTCGATTACTGCAGACCTCCAACATCACCAAGTCGGAGCAGAAGAAAAACCCGCAGGCCGTTCTAGACGTGCTCAAGTTTTACGACTCCACAGGCAACGGCAGACAGAAGTACCTCAGTTTCTCCTCAGAGAAGGACAGCTTTCCCTCCGGTGAACAGTCGCCTGCAAAGAAAACTCCAGAGCCGTCGTCTCCAGTCAAAGCAGTGGATGATGAAGATAATGGTGAAGATgaagacgatgatgatgatgaagaaacgCCGCCGCCTGTCGTCGCACCCCGGCCTGAACACACTAAGAGCGTATACACTCGACCGTCGGTCATCGACCCACTCCCCCCGCCGGTGACGTCTCCAGAAAGTGACGCAGCGTCGAAGGCCACTGACCGACAGAGACCCAAAAAGGGCAAGATGACGGACGAGGAGATCATGGACAAGCTCAGAACCATAGTCAGCATTGGAGACCCCAAAAAGAAATACACACGATACGAGAAGATCGGACAAGGAGCGTCAGGAACCGTGTTCACCGCAATAGACGTCGCCACTGGACAGGAGGTGGCCATCAAACAGATCAACCTGCAGAAACAGCCCAAGAAAGAGCTGATCATCAACGAGATCCTCGTCATGAAGGAGCTGAAGAATCCAAACATCGTCAACTTCTTAGACAGtttTCTTGTAGGTGAGGAGCTGTTTGTGGTGATGGAGTATTTGGCCGGCGGGTCGCTCACCGATGTCGTAACTGAGACCTGCATGGATGAAGCTCAGATCGCCGCTGTGTGCAGAGAGTGTTTGCAGGCGCTGGAGTTTCTTCATGCTAATCAGGTCATTCATCGAGACATCAAGAGCGACAACGTGCTTCTAGGAATGGACGGTTCTGTCAAACTCACGGACTTCGGTTTCTGTGCCCAGATCACTCCCGAACAGAGTAAGAGGAGCACGATGGTGGGTACGCCGTACTGGATGGCTCCGGAAGTGGTGACGCGCAAAGCCTACGGACCCAAAGTGGACATCTGGTCATTGGGCATCATGGCTATCGAGATGGTGGAGGGAGAGCCGCCGTATCTCAATGAGAATCCACTGAGGGCGCTGTACCTGATTGCAACCAATGGCACTCCAGAGTTGCAGAGTCCCGAAAAGTTGTCGCCAATCTTCCGAGACTTCCTAGGTCGCTGTCTGGAAATGGACGTCGAGAAGAGAGGTGGAAGCAAAGAGCTTTTGCAGCATCCCTTCCTGAAGTTGGCCAAACCTCTCTCCAGTCTCACTCCTCTAATTCTGGCCGCCAAGGACGCCATGAAGAACAACCGCTAGCATCCCGCTAGGAACGAGCTGTGCTCGCGAGCGCAGCGGACTGCTGAACACtctcgaaaaaaaaaatctgtgccaGGTGTTTTTACCAAGTGTGTCAACAACATAtctgtgttgccaaaacaaaaactccaaGCATTTCATTTTGGGTCTTTGCCTGTTTTTAAACCTATATTGACCGCTGTGGTATTTGGAGGGCCATTAGACGGTCCTCCCCATCTCATTTAGATTCTTGTGGGACTTTGTCTGTGTTTTACGTATGAACTCTTCCACTCTTTTTGGCTTCTGTAGACCTCGCATCTTCCATGATTGACGACCGGATCAGTTATGGCGAATTCAGATGCAGCTGGAGACGTTGTTTTGCTAGTCTTTCTGTAGCCAGAATCACGACTGAAAACTGTGTAGCCTACTCCTGTTCTTGACCCGAAGGGAAGAGCACTTTACCAATACACGCCAACTGCGAGCAGTGAATGATTTTTTGTAGTCACTCGTGCCTTTGTTGTTATTCCAGCAAACACCTTTATATACTCTGTCAGAAACAAGCAGATTATTTTGCCATCGAACTTCCTCTAACCTGAGACGTGACGAAACTTTTCATGTGATGAAGTTGTATGTATAGGATGACGTACTCCGAAGAAGCGTAGCATTTCAGTTGACGTAGTTAGCAATGAAACAGGGATGCGTACTGTAGATTAGAttattgtgtatgtttgtgtacatGAACACTCTTCTGTTGTCCTTTTAGTAACGGTTTAAGTAAATGCGGTTGTCATGATGTAAGAATTGATGACTATTTTTATGCTTGTCGGTCTCACTCGTTTTGCAAGTAAAATCCGGACTCCTGCAAACTCTGTGAACAATCCATGGTCATTGCAACGTCTGTGTACATCTCTTGTTCTTCATTAAAAGAGGACTTGAAACTTGACATCAGAATAAACTTTCATGAGTTAATGGGGTCGTTCCTGTTATGCCGTGACATTTATAGTAATTGTGCCATGCTTCTGTAaattaatgagttttttttaaagagcgtAAACACTCATTCATTATAACTTGATTAATTTGCACATTACTCTGAGTGCTTGACTTTTTtaacatttgtgtttgtgtgtgtgtggagggttTTTGGTAGTAAATATCACATCAAAGTAGTATTCGTGAGATGATCAGTACTTGTTCAGGTCTATGTGGTGTGTTTCCCGTCAAAGGTGATTTCACTTCCTGCTTCTGAGAGGTAAATATAATACACTTTTCTTGTCTTATTTGCAAATATCTCCTTAAACCATGGTGAAATCATTTTCAGTTTTGATCAAATGgggtttttaaataatcaaacaatCCTTGTTTGTcatgttggggatgttttcatgcactctggggtgattttgagtcttaatttggccacaactttctctgttttcTTAGCAAATGAAATGTTTGTTGGTGatatcttattttgacacattttgggaaaatgctttgaacatTTTGAAAAATCCAATGCACTCTGGgcactaccctttcattatgtttgtggctgtttttgccccattgacttcattataatgacatttttgattgcaaagccatgacacaatataatcatgcattcttaagAGGTAAAATATCCTTTTTTCTGTTGCTTTTTCTGTTGCAGTACAAAAAAGTTTAGTTTCTGCCTTCTATATAGAATATAGTGTGTGTgagacctttgcacacttatTTTGATGGCtgataaaatctaaatatgcagctcagctctcagaacatagtataaatatataagtgtattcatgcacacacactccaTAAAACTCCGTATAAAAGCTAGAAACTTTTTTTGCACAGTTAATGGTATCAGCTGATGATCATTTTACTTTTCTTATTTGCAAATATCTCCTGAAACCATGGTGAAATAATATTCAATTTAGATCAAATGGGGAAACAAAAGGTTTATATATAATCAAAGAACCCTTGTGTGTGCTGTTTGGGATGTTTTCATGCACTCAGGGGTCATTTTTAAGTCTTAATTCCGCCACAACTTTGTTTTCTTaacaaatggaatgattttttggtgaatattttgacattattttgacatattttgggaagatgctttaaacatttttttttaaaccaatgcaCTCTTGGCACTACCCTTTCATAACGTTTGTGACTGATTTTGCCCTATTGGcttcattataatgacatttttctgattgcaaagccatgacaccatataatacTGCGTTCTTGAGAGGTAAAAtatgctatatttattattaatcaaacaatccTTGTTTGTcatgttggggatgttttcatgcactctggggtgattttgagtcttaatttggccacaactttctctgttttcTTAGCAAATGAAATGTTTGTTGGTGAtgtcttattttaaaacattttgggaaaatgctttgaacatTTTGAAAAATCCAATGCACTCTGGgcactaccctttcattatgtttgtggctgtttttgccccattgacttcattataatgacatttttgattgcaaagccatgacaccatataatcatgcattcttaagaggtaaatatcatttttttctgttgatttttctgttg
>TCONS_00040904
AATGCCGCCGCACCGGAAGCAGCGTCTGTCTGTTAGCTGCAGGCGAGGGCAGAAAGAGACGCTGCTGGGCGCCTCCCCTTCCCCAAACCGACACAAAAAAGCACCGAAAATCAGCGATAATCTGCGGCGGATAGCGGCCCGAAGAGCGCAGGCCCTCCGCGGACAGAGCAGCACCGGCGGAGCGGCTCCAGCTCCAGTCTGAGCTCCGTTTCATAGCTCTAACTCctccttctctttctcttttgtTTTCTCTTCTTTCTCCTCCAACGCTCCTCCTCTCTTTCCTCCTGTCTCCTCATCCTGATCATGTGTGATAATGGCGATGTGGAGGACAAGCCGCCCGCTCCGCCTGTCAGGATGAGCAGCACCATCTTCAGCGGCGCCAAAGACCACGCCCTCACCGCCAATCACAGCTCCAAGCCCCTCCCATCGGTCCCAGAGGAGCGCAAGCGCAACAAGATCTACTCCATCTTCTCCGGCGCAGAGAAAGgtggaCGCAGGAAGGATCGTGATAAAGAGCGTCCTGAAATCTCTCCACCGTCAGACTTCGAGCACACCATTCATGTGGGATTTGACGCCGTTACTGGAGAGTTCACTGGAATGCCGGAGCAGTGGGCTCGATTACTGCAGACCTCCAACATCACCAAGTCGGAGCAGAAGAAAAACCCGCAGGCCGTTCTAGACGTGCTCAAGTTTTACGACTCCACAGGCAACGGCAGACAGAAGTACCTCAGTTTCTCCTCAGAGAAGGACAGCTTTCCCTCCGGTGAACAGTCGCCTGCAAAGAAAACTCCAGAGCCGTCGTCTCCAGTCAAAGCAGTGGATGATGAAGATAATGGTGAAGATgaagacgatgatgatgatgaagaaacgCCGCCGCCTGTCGTCGCACCCCGGCCTGAACACACTAAGAGCGTATACACTCGACCGTCGGTCATCGACCCACTCCCCCCGCCGGTGACGTCTCCAGAAAGTGACGCAGCGTCGAAGGCCACTGACCGACAGAGACCCAAAAAGGGCAAGATGACGGACGAGGAGATCATGGACAAGCTCAGAACCATAGTCAGCATTGGAGACCCCAAAAAGAAATACACACGATACGAGAAGATCGGACAAGGAGCGTCAGGAACCGTGTTCACCGCAATAGACGTCGCCACTGGACAGGAGGTGGCCATCAAACAGATCAACCTGCAGAAACAGCCCAAGAAAGAGCTGATCATCAACGAGATCCTCGTCATGAAGGAGCTGAAGAATCCAAACATCGTCAACTTCTTAGACAGtttTCTTGTAGGTGAGGAGCTGTTTGTGGTGATGGAGTATTTGGCCGGCGGGTCGCTCACCGATGTCGTAACTGAGACCTGCATGGATGAAGCTCAGATCGCCGCTGTGTGCAGAGAGTGTTTGCAGGCGCTGGAGTTTCTTCATGCTAATCAGGTCATTCATCGAGACATCAAGAGCGACAACGTGCTTCTAGGAATGGACGGTTCTGTCAAACTCACGGACTTCGGTTTCTGTGCCCAGATCACTCCCGAACAGAGTAAGAGGAGCACGATGGTGGGTACGCCGTACTGGATGGCTCCGGAAGTGGTGACGCGCAAAGCCTACGGACCCAAAGTGGACATCTGGTCATTGGGCATCATGGCTATCGAGATGGTGGAGGGAGAGCCGCCGTATCTCAATGAGAATCCACTGAGGGCGCTGTACCTGATTGCAACCAATGGCACTCCAGAGTTGCAGAGTCCCGAAAAGTTGTCGCCAATCTTCCGAGACTTCCTAGGTCGCTGTCTGGAAATGGACGTCGAGAAGAGAGGTGGAAGCAAAGAGCTTTTGCAGCATCCCTTCCTGAAGTTGGCCAAACCTCTCTCCAGTCTCACTCCTCTAATTCTGGCCGCCAAGGACGCCATGAAGAACAACCGCTAGCATCCCGCTAGGAACGAGCTGTGCTCGCGAGCGCAGCGGACTGCTGAACACtctcgaaaaaaaaaatctgtgccaGGTGTTTTTACCAAGTGTGTCAACAACATAtctgtgttgccaaaacaaaaactccaaGCATTTCATTTTGGGTCTTTGCCTGTTTTTAAACCTATATTGACCGCTGTGGTATTTGGAGGGCCATTAGACGGTCCTCCCCATCTCATTTAGATTCTTGTGGGACTTTGTCTGTGTTTTACGTATGAACTCTTCCACTCTTTTTGGCTTCTGTAGACCTCGCATCTTCCATGATTGACGACCGGATCAGTTATGGCGAATTCAGATGCAGCTGGAGACGTTGTTTTGCTAGTCTTTCTGTAGCCAGAATCACGACTGAAAACTGTGTAGCCTACTCCTGTTCTTGACCCGAAGGGAAGAGCACTTTACCAATACACGCCAACTGCGAGCAGTGAATGATTTTTTGTAGTCACTCGTGCCTTTGTTGTTATTCCAGCAAACACCTTTATATACTCTGTCAGAAACAAGCAGATTATTTTGCCATCGAACTTCCTCTAACCTGAGACGTGACGAAACTTTTCATGTGATGAAGTTGTATGTATAGGATGACGTACTCCGAAGAAGCGTAGCATTTCAGTTGACGTAGTTAGCAATGAAACAGGGATGCGTACTGTAGATTAGAttattgtgtatgtttgtgtacatGAACACTCTTCTGTTGTCCTTTTAGTAACGGTTTAAGTAAATGCGGTTGTCATGATGTAAGAATTGATGACTATTTTTATGCTTGTCGGTCTCACTCGTTTTGCAAGTAAAATCCGGACTCCTGCAAA
>TCONS_00040905
CTGTTAGCTGCAGGCGAGGGCAGAAAGAGACGCTGCTGGGCGCCTCCCCTTCCCCAAACCGACACAAAAAAGCACCGAAAATCAGCGATAATCTGCGGCGGATAGCGGCCCGAAGAGCGCAGGCCCTCCGCGGACAGAGCAGCACCGGCGGAGCGGCTCCAGCTCCAGTCTGAGCTCCGTTTCATAGGACAAGCCGCCCGCTCCGCCTGTCAGGATGAGCAGCACCATCTTCAGCGGCGCCAAAGACCACGCCCTCACCGCCAATCACAGCTCCAAGCCCCTCCCATCGGTCCCAGAGGAGCGCAAGCGCAACAAGATCTACTCCATCTTCTCCGGCGCAGAGAAAGgtggaCGCAGGAAGGATCGTGATAAAGAGCGTCCTGAAATCTCTCCACCGTCAGACTTCGAGCACACCATTCATGTGGGATTTGACGCCGTTACTGGAGAGTTCACTGGAATGCCGGAGCAGTGGGCTCGATTACTGCAGACCTCCAACATCACCAAGTCGGAGCAGAAGAAAAACCCGCAGGCCGTTCTAGACGTGCTCAAGTTTTACGACTCCACAGGCAACGGCAGACAGAAGTACCTCAGTTTCTCCTCAGAGAAGGACAGCTTTCCCTCCGGTGAACAGTCGCCTGCAAAGAAAACTCCAGAGCCGTCGTCTCCAGTCAAAGCAGTGGATGATGAAGATAATGGTGAAGATgaagacgatgatgatgatgaagaaacgCCGCCGCCTGTCGTCGCACCCCGGCCTGAACACACTAAGAGCGTATACACTCGACCGTCGGTCATCGACCCACTCCCCCCGCCGGTGACGTCTCCAGAAAGTGACGCAGCGTCGAAGGCCACTGACCGACAGAGACCCAAAAAGGGCAAGATGACGGACGAGGAGATCATGGACAAGCTCAGAACCATAGTCAGCATTGGAGACCCCAAAAAGAAATACACACGATACGAGAAGATCGGACAAGG

Function

symbol description
pak2b Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within blood vessel development. Predicted to be active in cytoplasm. Is expressed in axial vasculature; endoderm; and nervous system. Human ortholog(s) of this gene implicated in ductal carcinoma in situ. Orthologous to human PAK2 (p21 (RAC1) activated kinase 2).

GO:

id name namespace
GO:0042981 regulation of apoptotic process biological_process
GO:0023014 signal transduction by protein phosphorylation biological_process
GO:0032147 activation of protein kinase activity biological_process
GO:0006468 protein phosphorylation biological_process
GO:0001568 blood vessel development biological_process
GO:0031098 stress-activated protein kinase signaling cascade biological_process
GO:0050770 regulation of axonogenesis biological_process
GO:0016310 phosphorylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-3759 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within blood vessel development. Predicted to be active in cytoplasm. Is expressed in axial vasculature; endoderm; and nervous system. Human ortholog(s) of this gene implicated in ductal carcinoma in situ. Orthologous to human PAK2 (p21 (RAC1) activated kinase 2).

Ensembl:

ensembl_id ENSDARG00000018476

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00040903 False 4221 mRNA 0.43 14 2895511 2922053
TCONS_00040904 False 2765 mRNA 0.51 15 2897273 2929156
TCONS_00040905 True 975 mRNA 0.57 8 2911366 2929127

Neighbor

gene id symbol gene type direction distance location
XLOC_020738 NA coding downstream 2965 2889663 ~ 2892546 (-)
XLOC_020737 aqp12 coding downstream 8574 2874838 ~ 2886937 (-)
XLOC_020736 NA coding downstream 67425 2814463 ~ 2828086 (-)
XLOC_020734 NA coding downstream 69810 2795028 ~ 2825701 (-)
XLOC_020735 NA coding downstream 88484 2799465 ~ 2807027 (-)
XLOC_020740 pigx coding upstream 2184 2931340 ~ 2937529 (-)
XLOC_020741 ing5a coding upstream 19955 2949111 ~ 3092136 (-)
XLOC_020742 lmnb2 coding upstream 191930 3121086 ~ 3152357 (-)
XLOC_020743 lonp1 coding upstream 231291 3160447 ~ 3182965 (-)
XLOC_020744 gpr35.1 coding upstream 323780 3252936 ~ 3261879 (-)
XLOC_020733 NA non-coding downstream 105973 2769742 ~ 2789538 (-)
XLOC_020747 NA non-coding upstream 418357 3347513 ~ 3347884 (-)
XLOC_020749 NA non-coding upstream 811430 3740586 ~ 3741284 (-)
XLOC_020750 NA non-coding upstream 954451 3883607 ~ 3886684 (-)
XLOC_020752 CU074310.1 non-coding upstream 1382647 4311803 ~ 4313118 (-)
XLOC_020756 NA non-coding upstream 1803851 4733007 ~ 4735337 (-)

Expression


Co-expression Network