XLOC_020743 (lonp1)



Basic Information


Item Value
gene id XLOC_020743
gene name lonp1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007133.7
NCBI id CM002906.2
chromosome length 39133080
location 3160447 ~ 3182965 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00040912
taaaatacAAATACGATACAAAGTAAATTTAAAAGTACCGATGTTAGAGGGGGATTATTTAATAAGATAATGTTTTCCTAGACGCGAGCATCAGCAGCTggatcccttctagactttaccatGAAGTGGGCGTGATTTCAATGTCGTCATCACAACTTGACAGCCGGCCGCGCGGTCATGTGCTCGGCGCACAGAATCCTCCAGATCAAAGATGGCGGCGTACATGAGAGTGTGGAGATCCTCCAGCGGCAGCGGCTCCTCTGCGATCATCAGAGCCGGGATTAACGCGCTGTTTCCCCGCCTCACGCTAGGCAGCAGCCGCTCCTACTCCATCATCCGCAGCAGAGACTGTTTATCCGCCGCCCGGAGAAGCGCATCACTGACGGATAGGTGGAGTGGTGGTGGGTCTGCGGGCTCAGGGGGCTTAACGGGCGGCTGTCAGACGCGCTCGGTGTTCGGGAACAGGAGCAGTGGTTTCTCCGGGGAGGACGGCGCGGAGAGCAGCGGGACGGCCGATGGGGACGGCGGGGATGAAGCACCGGACTCCCCGCCGCAGATGAGCGCGCTCACGCCGATGCTCGTACCCGAAGTGTTCCCGAACGTGCCGCTGATCGCCGTGAACCGTAACCCGGTGTTTCCGCGCTTCATCAAGATCATCGaggtgaagAACAAGCAGCTGATGGAGCTGTTGAGGAGGAAAGTGCGGCTCGCTCAACCGTACGCTGGAGTGTTTCTGAAGAGAGACGAcagTAATGAGTCTGATGTTGTGGAGTCTCTGGACGCTGTTTATCACACCGGGACGTTCGTTCAGATCCACGAGATGCAGGACCTCGGAGATAAACTGCGCATGATCGTCATGGGCCACAGGAGGATCCGCATCAATAAGGCTTTGTCAGTGGAGCCAGAGGAGCCGGAGCCAATGGAGGCTGAAGCAGAGGAGCAGAAATCGTCCCGCAGGAAGCAGAAGCGTTCCCGCAGAGAGCCAGAGCCGCTGGCCGATCTGATGGAGCAGACGGTGCGAGAGGCAGATCTGCGGGTGGAGGCTCTTCCTCCGCCCTCAGTCCTCATGGTGGAGGTGGACAACGTGGCCCACGAGGAGTTCCAGGTCACGGAGGAGGTCAAGGCTTTGACAGCTGAGATCGTCAAGACGATTCGTGACATCATCGCTCTGAACCCTCTGTACAGAGAATCTGTGCTGCAGATGATGCAGGCCGGTCAGAGAGTGGTGGATAACCCAATTTACCTGAGCGACATGGGGGCGGCGCTGACCGGAGCCGAATCACATGAGCTACAGGATGTCCTGGAGGAAACTAACATTCCCAAACGACTCTACAAGGCCCTTTCTCTGCTAAAGAAGGAGTACGAGCTGAGCAAACTACAGCAGCGCCTTGGGAGGGAGGTGGAGGAGAAGATCAAGCAGACGCACAGAAAGTACCTTCTCCAGGAGCAGCTGAAGATCATCAAGAAGGAGCTGGGCTTGGAGAAGGAGGACAAAGACGCCATCGAGGAGAAGTTCAGAGAGCGGCTGAGGGATCGCACCGTTCCTCAGCACATCATGGACGTCATTAACGAAGAGCTCAACAAACTGGGCCTGCTGGACAACCACTCGTCAGAGTTCAATGTAACCCGTAACTATTTAGACTGGCTGACCTCCATGCCATGGGGCACCAACAGTGAGGAGAACCTGGAGCTTCGGCGAGCCAAAGAGGTGCTGGAGGAAGACCACTATGGAATGGACGACGTCAAGAAACGCATTCTGGAGTTTATAGCGGTAAGCCAGCTAAGAGGCAGCACACAAGGAAAGATCTTGTGCTTTTATGGACCTCCCGGAGTTGGCAAGACCAGTATCGCCCGCTCAATCGCCAGAGCACTTAATCGAGAATACTTCCGCTTTAGCGTTGGAGGAATGACGGATGTGGCGGAAATTAAAGGCCACAGGAGAACATATGTTGGTGCAATGCCAGGAAAGATCATTCAGTGTCTAAAGAAAACAAAGACTGAAAACCCATTGGTCCTAATTGATGAGGTTGACAAAATAGGTCGAGGATACCAGGGCGACCCTTCTTCGGCACTACTTGAGCTCTTGGATCCCGAACAGAACGCTAACTTTCTTGACCACTACTTGGATGTGCCGGTTGACCTGTCTAAGGTGCTGTTTATCTGTACAGCCAACATTACTGACACCATCCCTGAACCCTTAAGAGACCGAATGGAAATGATAAACGTATCAGGCTACGTTGCTCAGGAGAAACTGGCCATTGCGGAGAAATACCTGGTGCCCCAGTTGCGAACTCTTTGCGGTTTGGATGAACAAAAGGTGAAAATCAATCCTGAGGCTCTAAACCTGCTCATCAGACAGTACTGCAGAGAGAGCGGCGTCAGGAACCTTCAGAAGCAAGTCGAAAAGGTTTTCCGGAAAGTAGCGTTCAGGATTGTCAGTGGTGAGGAAACAGCGGTCGATGTCACATCGAACAACCTTCAGGATTATGTTGGAAAGCCTCTCTTTACTGTAGACCGAATGTACGACGTCACACCGCCAGGAGTTGTCATGGGCCTGGCATGGACGGCAATGGGTGGTTCGACGCTGTTCATCGAGACGTCTCTGAGGCGGCCCAGAGATCCGCCGGGGAAAGATGGTCCCAAAGACGGATCGCTGGAGGTCACTGGACAGCTGGGAGACGTGATGAAGGAAAGCGCTAAGATTGCGTACACGTTTGCTCGCTCGTTCCTCATGAAGGAGCAACCAGACAATGAGTTCCTCGTGAGCTCCCATATTCACCTCCATGTGCCTGAGGGTGCGACTCCTAAAGACGGCCCCAGCGCCGGATGCACCATCGTCACGGCTCTGCTGTCTTTAGCCACAAACACAGCTCTGCGTCAGAACGTTGCCATGACTGGAGAGCTATCCCTGACTGGCAAAATCCTGCCTGTTGGAGGAATCAAGGAGAAGACCATTGCTGCGAAGAGAGCCGGCGTGACCTGCATTATCCTGCCGGCGGAAAACAGAAAGGATTTCTCGGATCTGCCTGAATACATCACTGAAGGCCTGGAAGTGCACTTCGTGGAAAACTACAGCGAGATCTACAACCTTGTGTTCTCCACACCGAAATAAGCATTTTATAAGGAAGAGTCTTCATTTACGAAGTACTTCTGATTGAGGAAACGGAGAGTTTTGTTTTATCCACAGAAGGAAAAGTCTGAATGATGAACGATTGCATCGTGATTCCTGAAGCGTTCCAGACTCTGGGGTCCTGCCATCGCTGCCGCGCAGCCTTTATTGATGATTTTTATATTCAGTTCAGCTCATCTCATCACGTGTCATAAGTGTAAATATCTGCCTTAAATGTATTTCTCTCAAATCttctacaataaataaatatatatatatattatggaacTGTGTCTTGAAAAAGTCAAGTCCCTTCTAAGAATCTGGTCTTCATTAGTGCTGTAGTGGTTAATTATGGCCAATGTTTGGGGAAAAAGTAATAtatcactatctatctatctatctatctatctatctatctatctatctatctatctgtctgtctgtctttctttctctgtatgtatatatatatatatatatatatgtatatatatatatatatatgtatatatatatatatatatgtatatatatatatatatatgtatgtatatatatatatgtatgtatatatatatatatgtatgtatatatatatatgtatatatatatgtgtatatatatatatgtatatatatatatatgtatatatatatatgtatatatatatatatatatatatatatatatatatatatatatatatatatatataatgtatgtatgtgtgtatatatgtatgtgtgtgtgtgtgtgtgtgtgtgtatatatatatatatacacacacacacacacatatctgtgtgtgtgtgtattaatattacatatattttctaaagtttttttttaagtagcagttaaatgtgttaattaggtactattttgaggaaaataatgtaaaaatatgttgttgttgttttttttagagtAATATgcttaaaattgaaataaataaccaATTTTTTAAGCACAACACTGAACTTGACtaattttatagaaaat
>TCONS_00040913
GAGAAGGAGGACAAAGACGCCATCGAGGAGAAGTTCAGAGAGCGGCTGAGGGATCGCACCGTTCCTCAGCACATCATGGACGTCATTAACGAAGAGCTCAACAAACTGGGCCTGCTGGACAACCACTCGTCAGAGTTCAATGTAACCCGTAACTATTTAGACTGGCTGACCTCCATGCCATGGGGCACCAACAGTGAGGAGAACCTGGAGCTTCGGCGAGCCAAAGAGGTGCTGGAGGAAGACCACTATGGAATGGACGACGTCAAGAAACGCATTCTGGAGTTTATAGCGGTAAGCCAGCTAAGAGGCAGCACACAAGGAAAGATCTTGTGCTTTTATGGACCTCCCGGAGTTGGCAAGACCAGTATCGCCCGCTCAATCGCCAGAGCACTTAATCGAGAATACTTCCGCTTTAGCGTTGGAGGAATGACGGATGTGGCGGAAATTAAAGGCCACAGGAGAACATATGTTGGTGCAATGCCAGGAAAGATCATTCAGTGTCTAAAGAAAACAAAGACTGAAAACCCATTGGTCCTAATTGATGAGAAATACCTGGTGCCCCAGTTGCGAACTCTTTGCGGTTTGGATGAACAAAAGGTGAAAATCAATCCTGAGGCTCTAAACCTGCTCATCAGACAGTACTGCAGAGAGAGCGGCGTCAGGAACCTTCAGAAGCAAGTCGAAAAGGTTTTCCGGAAAGTAGCGTTCAGGATTGTCAGTGGTGAGGAAACAGCGGTCGAT

Function


symbol description
lonp1 Predicted to enable ATP-dependent peptidase activity and single-stranded DNA binding activity. Predicted to be involved in chaperone-mediated protein complex assembly; mitochondrion organization; and protein quality control for misfolded or incompletely synthesized proteins. Predicted to act upstream of or within protein catabolic process and proteolysis. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in CODAS syndrome. Orthologous to human LONP1 (lon peptidase 1, mitochondrial).

GO:

id name namespace
GO:0051131 chaperone-mediated protein complex assembly biological_process
GO:0030163 protein catabolic process biological_process
GO:0007005 mitochondrion organization biological_process
GO:0006508 proteolysis biological_process
GO:0034599 cellular response to oxidative stress biological_process
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins biological_process
GO:0070407 oxidation-dependent protein catabolic process biological_process
GO:0005759 mitochondrial matrix cellular_component
GO:0005739 mitochondrion cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0004176 ATP-dependent peptidase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008236 serine-type peptidase activity molecular_function
GO:0003697 single-stranded DNA binding molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-4006 Predicted to enable ATP-dependent peptidase activity and single-stranded DNA binding activity. Predicted to be involved in chaperone-mediated protein complex assembly; mitochondrion organization; and protein quality control for misfolded or incompletely synthesized proteins. Predicted to act upstream of or within protein catabolic process and proteolysis. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in CODAS syndrome. Orthologous to human LONP1 (lon peptidase 1, mitochondrial).

Ensembl:

ensembl_id ENSDARG00000102765

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00040912 False 4114 mRNA 0.47 18 3160447 3182965
TCONS_00040913 True 741 mRNA 0.50 6 3164642 3172823

Neighbor


gene id symbol gene type direction distance location
XLOC_020742 lmnb2 coding downstream 8090 3121086 ~ 3152357 (-)
XLOC_020741 ing5a coding downstream 68311 2949111 ~ 3092136 (-)
XLOC_020740 pigx coding downstream 222918 2931340 ~ 2937529 (-)
XLOC_020739 pak2b coding downstream 231291 2895511 ~ 2929156 (-)
XLOC_020738 NA coding downstream 267901 2889663 ~ 2892546 (-)
XLOC_020744 gpr35.1 coding upstream 69971 3252936 ~ 3261879 (-)
XLOC_020745 si:zfos-943e10.1 coding upstream 79448 3262413 ~ 3299355 (-)
XLOC_020746 tbxa2r coding upstream 153758 3336723 ~ 3344613 (-)
XLOC_020747 NA coding upstream 164548 3347513 ~ 3347884 (-)
XLOC_020748 ptprsa coding upstream 206382 3389347 ~ 3680725 (-)
XLOC_020736 NA non-coding downstream 332361 2814463 ~ 2828086 (-)
XLOC_020734 NA non-coding downstream 334746 2795028 ~ 2825701 (-)
XLOC_020735 NA non-coding downstream 353420 2799465 ~ 2807027 (-)
XLOC_020733 NA non-coding downstream 370909 2769742 ~ 2789538 (-)
XLOC_020749 NA non-coding upstream 557621 3740586 ~ 3741284 (-)
XLOC_020750 NA non-coding upstream 700642 3883607 ~ 3886684 (-)
XLOC_020752 CU074310.1 non-coding upstream 1128838 4311803 ~ 4313118 (-)
XLOC_020756 NA non-coding upstream 1550042 4733007 ~ 4735337 (-)

Expression



Co-expression Network