XLOC_020994 (s100b)


Basic Information

Item Value
gene id XLOC_020994
gene name s100b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007133.7
NCBI id CM002906.2
chromosome length 39133080
location 13846130 ~ 13857729 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00041287
TTCTCTTTGGAGTTTTCAAAGAGCTGGATTGTGTTTCTAACGTGCTAACACAATAGTGGCGATGCCCTCTTGTGGTCATATAAGGAATACTTTTCAACTACGATTCGGATGAAGTAAATGTcaacctttgatttttttaaagcttttcatattaaaaacggatgattttttttattagagcTTGAGGGAACCGGGACTCTCAGCAGCAGCACCCGGAGATCTGCCCTCGTCCGTTACCGTGGCGCATTTCCAGCGATGACTCAGCGTTTGGCGAACCTTTCTGGCTCAGCGAGAGGCGGGGAAAAACCGCCACTGCAGCGCGGCAACAGGTCATCGCCAACGGCAACAGCCAAAGCGACAGGAAGGCTAACCTATAAATGGACTCTCATCTCCCTCTGCAGAATCGCCTCTTTCTGACAAACTCTCTGCTGGTAAGTCTAGTACGTTTTTATTTATCATTCCAATgtttttaaagcttattttgcTCCAAGCTTTTCCAAACTGAGGatgaaattgcaaaaaaaaaaaaaaaaaaaactacataatgACTAGAAATGTGTTTGCAAAAGTGAAAGACAGAACGAAACTTAATGGTCTATAAAATTGCTCCGACACTTAAACTTGTTTGCAGACATTTGAGGGAAAAAGTTAAACAGCTTGAAATTGCTATCAagcatttttcacatttttagtaATTATTCCAGGAAACGTTGAGCGTCGCTGCAGCACATTAAGATGTCAGACTTAGAGAACTGCCTGGGAACCATCATTGAAGTCTTCCACAAATACTCGTCGAAAGAAGGAGACAAGTACAAATTAAAAAAGAGTGAACTCAAGGAGCTGCTCACGCATGAGTTTCCAACTCTCACTgagCAAGTGAAAGACCAAGCTACAATGGACAGTTTGATGGAAAGTTTGGACACCGATGGCGACTCGGAGTGTGATTTCCAGGAGTTCATGACCTTCGTCACCATGGTTACCATCTGTTGCCATGAGTTTTTCGAACACCATGAAGACGAATGAGTCTAAATAAAAGAAAGTAGTTTTCGTAGTTTAATGAGTCTCAATACATTTCTTCAGTAAACTTTACTTCGTTCTCATCGCATTAggattgttttattgttgttgtttgtttggacAGAATGTACATGCAGCTTgtctgacaatttagcttatttctGCTAGACTCGAAAATCAGTTCGTAATTTATTACAAAGCATGCTTCTATTATTTTGGCTAGACATTTGTTTCAAGACATGGCCATCATAAATCTCATCGAGTGGAATGCGGATCCAGGTGTTTTACTCTTGTCATTTCAATTCCAGGCtgattgtgaaatgttttttttcttttgattagcTTCAGACTATTAGGCTGCTATTGACTTTTGTCAGATTGTTCCGGGGCCTTAGACAAATCACACTGTGCTTTAAAAAGACCCACCAAAGCGAATTATTCTTCTGAGCATCTTGTATGATGTTTATGACCATCCATAAATGATGTAGATTTGCAAATCAATCCCATACGAACTGTTagaatgaatgtttattatgtCTTGAATGCCCtattatttgtgtgttttcaaCTGTAACCTACGCTTATAGTCAGTGTTTCGAATCTTCTGCCTTTTTCATGAAagaaataagatttaaaaataaatgtgtttgccacagtttatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatataagaacaaTTTACACCAAAATCCAAATGAATAAAGACCTacaatgaatgtttctttaaaagGTCAATCAAAAAGTGAACAAATTGCAGAAGCCAAACTCTTAAAATTCTGGAATGAAAACTAGCTCAAGAAAATAAAGAACAGATGACATTCAGTAATGTGTGGACAATTTTATGAAACATTGATTGcattagttttaaaatatatctatctatctatctatctatctatctatctatctatctatctatctatctatctatctatctttataatttcatttaaaaataatgtttgatgAAAATATATAGtcctatctatctatatctatcgcTTTttcattcagtaaaaaaaaaaaacatttgataaaacTATATATAGATAGATTGGACTATATATTTTCATCAAACATGTGTCTGCTGGGATAATTGGAAACTTAATTAGCGATAAAGGGGTCAAATGTCTGGTGTAGCCTACATGTCAATCATTAATTAGGTACTTGTAATTTAAAGGCATTTGTGAAAAGCATCCGGCACTCGCTGGGATACAGGATATAATTGATCATTACCTTTTATAAAACCAAGAAAGTCGTTTCCTAAATGTTCTGGAGTTAAGCTTACCTTACATTCTctttcagggaaaaaaaaaatgtccgcTTCCTCAGCTCCAAACAACCGCGTGTCCCTTGTGACTTCCATTGATTTGGGTGTCCCGCAGGGATTCTCATTACCGAGCACAAACTGTCAATACGGAGGCCTTCACATCCGTGTGCTAATTAACGGATCAATGGCCGCCCCTACAAGACCCCAAAAGATGATAAATATTATCTCCACACGACTTTCTTAAGAACAGCTACGTGCTTTATCTCAAGTTTGTTTACATTTAGCGGTTTGGAAATCTGCCATGTTTATATGCAGTATACAtacccaaacaaacaaatacaagtgtgtttgaaggacatttgactttttttaagcTAATCACGGGTTGTTGTACTAAATATAACCGCTAGGTGGCGGTGTTGTGCCGCGGCTGCACAGGCTTGGGAAATGAGAAATGCGTCGAGTTGAAGAGTGGACgcaatatgattttaaaaaaaggcaCTGGATTTATTTGACAATGcaataaagcataaataaaacatgataaaGAAATAAGTG
>TCONS_00041288
CTGCAGAATCGCCTCTTTCTGACAAACTCTCTGCTGGAAACGTTGAGCGTCGCTGCAGCACATTAAGATGTCAGACTTAGAGAACTGCCTGGGAACCATCATTGAAGTCTTCCACAAATACTCGTCGAAAGAAGGAGACAAGTACAAATTAAAAAAGAGTGAACTCAAGGAGCTGCTCACGCATGAGTTTCCAACTCTCACTgagCAAGTGAAAGACCAAGCTACAATGGACAGTTTGATGGAAAGTTTGGACACCGATGGCGACTCGGAGTGTGATTTCCAGGAGTTCATGACCTTCGTCACCATGGTTACCATCTGTTGCCATGAGTTTTTCGAACACCATGAAGACGAATGAGTCTAAATAAAAGAAAGTAGTTTTCGTAGTTTAATGAGTCTCAATACATTTCTTCAGTAAACTTTACTTCGTTCTCATCGCATTAggattgttttattgttgttgtttgtttggacAGAATGTACATGCAGCTTgtctgacaatttagcttatttctGCTAGACTCGAAAATCAGTTCGTAATTTATTACAAAGCATGCTTCTATTATTTTGGCTAGACATTTGTTTCAAGACATGGCCATCATAAATCTCATCGAGTGGAATGCGGATCCAGGTGTTTTACTCTTGTCATTTCAATTCCAGGCtgattgtgaaatgttttttttcttttgattagcTTCAGACTATTAGGCTGCTATTGACTTTTGTCAGATTGTTCCGGGGCCTTAGACAAATCACACTGTGCTTTAAAAAGACCCACCAAAGCGAATTATTCTTCTGAGCATCTTGTATGATGTTTATGACCATCCATAAATGATGTAGATTTGCAAATCAATCCCATACGAACTGTTagaatgaatgtttattatgtCTTGAATGCCCtattatttgtgtgttttcaaCTGTAACCTACGCTTATAGTCAGTGTTTCGAATCTTCTGCCTTTTTCATGAAagaaataagatttaaaaataaatgtgtttgccacagtttatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatataagaacaaTTTACACCAAAATCCAAATGAATAAAGACCTacaatgaatgtttctttaaaagGTCAATCAAAAAGTGAACAAATTGCAGAAGCCAAACTCTTAAAATTCTGGAATGAAAACTAGCTCAAGAAAATAAAGAACAGATGACATTCA

Function

symbol description
s100b Predicted to enable several functions, including RAGE receptor binding activity; S100 protein binding activity; and calcium-dependent protein binding activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of cell population proliferation. Predicted to be active in cytoplasm; extracellular space; and nucleus. Is expressed in several structures, including digestive system; heart; integument; nervous system; and renal system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B).

GO:

id name namespace
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0008284 positive regulation of cell population proliferation biological_process
GO:0005615 extracellular space cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0048306 calcium-dependent protein binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0044548 S100 protein binding molecular_function
GO:0050786 RAGE receptor binding molecular_function

KEGG:

id description
ko04990 Domain-containing proteins not elsewhere classified

ZFIN:

id description
ZDB-GENE-040718-290 Predicted to enable several functions, including RAGE receptor binding activity; S100 protein binding activity; and calcium-dependent protein binding activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of cell population proliferation. Predicted to be active in cytoplasm; extracellular space; and nucleus. Is expressed in several structures, including digestive system; heart; integument; nervous system; and renal system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B).

Ensembl:

ensembl_id ENSDARG00000057598

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00041287 False 2903 mRNA 0.36 3 13846130 13857729
TCONS_00041288 True 1229 mRNA 0.35 3 13847136 13851297

Neighbor

gene id symbol gene type direction distance location
XLOC_020993 CT990618.1 coding downstream 129545 13711434 ~ 13716585 (-)
XLOC_020992 NA coding downstream 152503 13668985 ~ 13693627 (-)
XLOC_020991 si:ch211-279g13.1 coding downstream 196526 13638586 ~ 13649604 (-)
XLOC_020990 NA coding downstream 238567 13606281 ~ 13607563 (-)
XLOC_020989 cntnap5b coding downstream 301886 13458735 ~ 13544244 (-)
XLOC_020995 BX649510.1 coding upstream 88224 13945953 ~ 13946067 (-)
XLOC_020996 BX649296.1 coding upstream 161875 14019604 ~ 14019722 (-)
XLOC_020997 aox5 coding upstream 226000 14083729 ~ 14115316 (-)
XLOC_020998 si:ch211-246m6.4 coding upstream 269743 14127472 ~ 14128716 (-)
XLOC_020999 si:ch211-246m6.5 coding upstream 287781 14145510 ~ 14161309 (-)
XLOC_020988 CU062647.1 non-coding downstream 414826 13422568 ~ 13431304 (-)
XLOC_020986 NA non-coding downstream 601579 13201478 ~ 13244551 (-)
XLOC_021001 NA non-coding upstream 418017 14275746 ~ 14298602 (-)
XLOC_021002 NA non-coding upstream 442071 14299800 ~ 14301873 (-)
XLOC_021004 NA non-coding upstream 474721 14332450 ~ 14334135 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location