XLOC_021474 (hck)


Basic Information

Item Value
gene id XLOC_021474
gene name hck
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 7505943 ~ 7545960 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00042682
ATTCATGACAGATTTCCTCTGACTATAAAGGATGTGGCTCAATACTCACTCCGTTCCCTACCTAGACAACACTTTAGGCGTAGTGCATGGTCTTGGAACCTTTCTGGTGGTAAATAGCTTGTTTTGAGTCTTGTATGCTCACTCAAGTGTTTCAGTATGAACTAAGCTGATTCTGAAAGCGTCTAATGGTAGTTGTCAGGCATCTCGGCGGTATTTGAGACACGCCCTGTTGAGCAGAACAGAAACGACAGTCTCAATATTCACTGAACTAAAGCGCATCACTGTGATGGAGAAGCCGGTGTGAAGGCACTGCAATTTTTTTCTGCTCGTAGGTCATTTGGCGATTTTTTTGTGAATAGCCTAAAGAAGTTTAACTTTTGACTGGATTGCGAGTGAAGCGGCCTCAACATGGGCTGTGTGGGGACCAAACCGGAGCAAGATCCTATTGGTAAATCAGTGAACAGCGATGACAACCGCAACGTGGCACATTACACCAAAGACCCCACAACAGGGGCCAAAGCTaacaGAACCACCTCCAATGCACAGACTCCTGGGACAGATACTTCAGAAAACATTGCCATCGCTCTGTATGACTATGAAGCCATGCATGAAGGTGACCTGGGCTTCAAGAAAGGAGATCGGCTCAGAATCCTGCAGGAGTCCGGTGAGTGGTGGAAAGCAGTAATCATCAGCACTGGTCAAGAGGGCTTCATTCCCAGTAACTATGTTGCCAAAGATACTCTGGAAACTGAAGAGTGGTTTTTTAAAGGTGTCAGCAGGAAGGATGCAGAGAGACAGCTGTTGGCCTCTGGAAACAAAACAGGCTCCTTCATGATCAGAGACAGTGAGACTACCAAGGGAAGCTACTCTTTGTCTGTGAGAGACAGCGACCATCAGGCTGACACTGTCAAGCATTATAAGATCCGCACACTGGATAACGGCGGTTTCTATATTTCCCCGCGAATCACATTCAACACCCTGCAGGACCTGGTCAGCCACTACAAAAAGCAGAGCGATGGGCTGTGCCAGTCTCTCACCTCTCCCTGTCTGAGTCCCAAACCTCAGAAGCCTTGGGAGAAAGACGCATGGGAGATTCCACGCGAGTCCCTCAAACTGGACAAACGTCTGGGAGCAGGACAGTTTGGGGAGGTCTGGATGGCAATGTACAACAAGCACACCAAAGTGGCGGTGAAGACTATGAAGCCTGGCAGTATGTCTGTGGAAGCTTTCCTTATGGAGGCCAACTTAATGAAAAGCCTACAGCACGACAAACTGGTCCGTCTCAACGCTGTGGTCACCAAAGAAGAGCCCATTTACATCATTACAGAGTTCATGGAGAAAGGCAGTTTACTGGACTTCATTAAAAGCGACGAAGGGAACCGAGTCCAGCTGCCCAAACTGATCGACTTCTCAGCACAGATTGCAGAAGGTATGGCTTACATTGAGCAGAGGAACTACATTCACAGAGATCTCCGTGCTGCCAACATCCTGGTCAACAAAAGTTTAGTGTGTAAGATTGCTGATTTTGGACTGGCACGTATCATAGAGGACAACGAATACACTGCTAGAGAAGGTGCAAAGTTCCCTATTAAGTGGACAGCTCCAGAGGCTATAAACTATGGCTCCTTCACCATCAAATCCGATGTGTGGTCTTTCGGCATCCTGCTGACTGAAATCATTAGCTATGGCCGCACGCCATACCCAGgGATGACCAACCCCGAGGTAATCCGTGCTCTTGAGAGAGGTTACCGCATGCAGCGTCTGGACTCCTGTCCTCAAGAGCTCTACGACATCATGCTAGAGTGCTGGAAGAACAAGCCTGAGGACAGACCCACCTTTGAGTACCTGCAGAGCGTGCTGGAGGACTTTTACACTGCCACCGAGAGCCAGTATCAGCAACAACcttgagaaaaacacacacacacatacacacacacacacaaaatatttcaatCCTTCACATCAGTAACTCTCAAAGAAATCAACACACACATCCACCTTTTTTCCTGCATGTGTCAATTGCATTTCAAACTATGGGTCTGTTTCGTGAACTTCTAATCAAAAGAACTGAATAAAACCCTTTTAGATGATAGAGTTGTACCACAAAAAGGAATCAATGAACAGTAACAGTTACATTTGGCCTCGTACTTTATTTTTATCCATCATTATAATTACGCTATGCTTAATGTTTTAAAGTAGCAGTCGAATCACAAGCACATCTGTGGCCAAAGCTCTTTTTTTGAGTTCACTGTGTTTAGTTCAGGCATCATGGtgggcaagaaggtcgctggttcgagtctcggctgggccagttggcatttctgtgtggagtttgcatgttctccccatgttcatgtgcgtttcctccaggtgctctggctttccccacagtccaaagacatgctctataagtgaattgaatcaaataaattggccgtagtgtatgagtgcgtgtatgAATTCAAGTATGactaggtgtttcccagtactgggttacagccaaaagggcatccactgcataaaacatatgctggaatagttggcggttatttccactgtggccaccctgggtaaataagcgactaagctgaaggaaaatgaatgtgcTTTGTTGGCCCAGATCATTATCTATTTCCATTCCCTTCAGTACAGTAATATTCAATGTATGGCTGTAATATTCCCCCTGAAAGATTTGTAGAGAGTAGTTTTGGGCATTATTTATATTAAGTAATGTAGTTTAAACTGTGCGCtcgtgtttttaaatattttggtgtGTTAAACTAGTTAATAATATTGTTCAGAAGGTCATGATTCACACTCAATACTTTGtatagctttattttacattcttaggagaaacaaaacacaatgccttcctcagtgcgTGACACAATCATCTCACACCACCCTTTTATCCCACAGTTAATCACATTATGTCATCAGTTAGACAAGTcataaacttctctgaccacatttctgcTCGATCATGCAGATTCGCACTTTATAACATctgaaagatccgacccttcttatctgaacatgcagctcaactccttgttcaagctcttgttctctccaaactggattactgcaactctctactagccgggcttccagctaactctatcaagcctcttcagctgcttcagaacgcagcagcatgagtggtctttaatgaacctaaaagagcacatgtcactccgctgctcatccgtttgcactggctgccagttgctgctcgcatcaaattcaaagctctgatgtttgcctacaaagcgacttctggctttgcttcttcttatctgctctctcttctgcagatctatgtgccctccagaaacttgtgttctgtggatgaacgtcgcctcgtggttccatcccaaagagggaagaaatcactttcccgaacgctcgcattcaatctgcccagttggtgtaATGatctccctaactgcatcagaacggcagagtcactcgctgttttcaagaaacgtcTAAAAActctatttagtctccacttcacttcctaatctgcaattgcctctctggatataccactaactatactaaaaaaataaaataaaaatgtattaatactttccttcttagactttacagacctgaaacttgcctataacacttattcattgttgctcttatagttgtgtaaattgcttccttgtcctcatttgtaagtcgctttggataaaagcgtctgctaaatgactaaatgtaaatgtaaaatgtacgtTTCAATATACTGTATTAACCACACTAAAAAATTGTGAAGACATTGTGCTGAAACGTCTGTGTTATGTTTCtcctaataatataaaataaagctatataaagtaattatttaatgagtgcgaatcatgaccttctgaaagatattatttactgtacgCCAAAATTTTGTTAattctataatttttttaaaatattcaatgaATGATTACAATAGACAACATGACATCTCTTtgtgcacaataaaaaaaaaagactgtccCTATTGATTGTACAATTTCAGTTATATGAATTTGAGATTTTCTAAACTACATGAAGATGGAAATCAGTGTATTACTCACTATCGGGAAAAGCGTAACGGCTAACATGGATTCCATAAGCGCCTCAGCCGATCATGTAACAGCTTTAAAATTGCTGGTCAGCATTTACAGTTGATAGACCTAGCTGATGCAGCATTCCCTATAATGCCTTTTTATCAGGGTAATGATTCACCATGAATGCATTGTTTAGTGTTTAACATGTTGAAGATCAGCGGAGAGGCTTTCGATTGATAAAATGACAAGTTGTTTAATCAGAAAAGCTGTTTATTCAGTAAAGTGACACCTCTCCTTCATTGacatccattaaaataaaaacgGCCTCAGGGCTCCTTCCTCAGGTACTGGCGTTAGCTGTTATGCCATTTCGGCGAATGACTTCCGGATTGTCATCTATTGTCTTGGGTTATTCTCATAATTCACGCAAAGCATCACAGGCTGCGGAAAAAAAGGTGGATAATTTATCCATGCCAACCCATTGACTTTATACATATGTAGTGATATCAAATGTGAAGGCGTAGGTgtgttatttaaatgatgtgtaaaTGAATACATTTCTAATTCCTGCACAGCCCTTTGCCTTACGCAGAGTGCTGCACAATAGAAGCTCTATAGttatcattttaatgtaaaacGCGCAAGAGATAATATTGTCCTTACTCactttactgatttattttatatatatatatatatatatatatatatatatatatatatatatatatatatatatattacatttttcgtgtatgtatatatatatatatatatatatatatatatacgaataATGTTATATCTTTAATAATGGAGTTATCACAGTTATTTAGAATAAGAGAtgattaatatatttttctaagACCAAAAAATTATGGTTCCCCTTCATAGGAACTCAGATGTGTGTCTAGACAAAGACACTTTAGGAGATCGCTACAACCAAAGTGTCTTTATCTAGACACATGTCTCTGTTCCCTATTTGGGGAATGAgggttacagttgaagtcagaattattaagccccctttaaattttttttcttttttaaatgtttcccaaatgatatttaacagagcaaggaaattttcacagtatgtctgataatattttttcttctggaaaaaatagtatcgttttattttggctagaataaaagcagttttagattttttaaaagccattttaaggacaaaattattagccccttcaagctatattttttcctgatagtctacagaacaaaccattgttataccaTGACttatctaattaccctaacctgcctagttaacctaattaaccctttaaatgtcactttaagctgtggagacaagtcttaaaaaatatctagtcaaatattatttactattatcacggcaaagataaaacaaatcagttattagatatgagttattaaatctatgtTTAGTAATCTGCTCTCCATTGAAAACTTGGAGAGAAAaaatattgggggaaaaaataaacagggatctactaattcaggggggctaataattctgacttcaactgtacattcttAACCGAGACATTCCTTTCATGGGAACTCTATTGTGTGTCTAGATAAAAGACACTTTGGTCATCTAGCGATTTCCCAAAGCGTCTTTATCTAGACACACGCCTCTGTTCCCTATTCGGGGAATGAGGGTTATGTTCGTAACCGAGACACACTTTTATACATAATCATAAGTTTCATAAATCATACAGAATATACCCAATAAcatgtcattcagtgtaacattcttgtcggcttagtccctttattaatccggcgtcgccacagcggaatgaaccaccaacttatccagcaattttttatgCAGcatccagccgtaacccatctctgggaaacatctacacacacattcaccacggacaatttagcctacccaatgtgggggaaaccggagcacccagaggaaacccacgcgaaggcagggagaacatgcaaactccacacagaaacgccaactgagccgaggttcgaaccagcaaccttcttgctgtgaggcgacagcattaactactgcgccactgcctcgcccttcaATGTAACAACAGTTTATAAAACTAAAAAGTTGTATGATTTAGAATAAGTTTcagaacatttagaaaaaaaaaagagtcatatTAAAGACTTTACACTGCATCACTCAATACTAATTACTTaccatttaaaatactttatgcTTTACCACAATCTATCAAACTACtaggttttacccatttgtcCGCAAGAGACTTTTAATCAGTTCAAATATGATCTAATTTAGCAAgagtttttattcttttatatatatttttatatattcacgGGTCagaataagtatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatctatagtgttacactgaatgaccatgaaacattatttcagccatattttaacattttatttgaaacctGAAATCATTTTCACTTGTATTTCATATGCTTTGTATATAAAACTAATTATTGTACATTTAGTTATTTGCAGACACCAAAATACAACGTCTCCTCTTTGTCCTATTGTGCATTGGAATTTAAAGTACACATTAAGGGCATTAAAATCAATTTTGATCACAAATTATTCCTAAAACCAACCTACATTAGGTTTCAGAGATGTTATTGTGGATTGCAAAATGTGAAATATGAATGTATTTGTTCAGGGGGGGGGAAactatattaactatattaaCTCATTAACTCAAGCATTTCAGAACATGTTCCTAAAAGGTAGTTATGAAGAAATCAGGTTATAGTTTTCAGTTAAATAGTACTACTTCTGTATTcaatttgtatgtatttgtaaGTTTATGCTTGCTTtctcagatttttgttttgttaatttaatacTTTTGCAAGCCTAAAGCTATTTATCGGTTAATGTGTGTCTTTTGGTGTGTGCATGTCTTCAGTTGCTACTGTATTTGTTTGAACTTTTGTGCAATAGTAAATGATATTTCTATCATTTATGACATTCTGTGGTTTCGTTCAGATTTCCTGCAAGCACAGAGACATTGCATTAGTGCCTTCATTAACATCAACATCCTTTGTGTGAGACGTCATGCTGGTTGATTTTACATATTTGTCTTttaaagaagacaaaaaaatatatatttttgtgtacaTGTTAAAAATGAGT
>TCONS_00042683
ATGGGCTGTGTGGGGACCAAACCGGAGCAAGATCCTATTGGTAAATCAGTGAACAGCGATGACAACCGCAACGTGGCACATTACACCAAAGACCCCACAACAGGGGCCAAAGCTGTAAGTAGAACTTCAGAAAACATTGCCATCGCTCTGTATGACTATGAAGCCATGCATGAAGGTGACCTGGGCTTCAAGAAAGGAGATCGGCTCAGAATCCTGCAGGAGTCCGGTGAGTGGTGGAAAGCAGTAATCATCAGCACTGGTCAAGAGGGCTTCATTCCCAGTAACTATGTTGCCAAAGATACTCTGGAAACTGAAGAGTGGTTTTTTAAAGGTGTCAGCAGGAAGGATGCAGAGAGACAGCTGTTGGCCTCTGGAAACAAAACAGGCTCCTTCATGATCAGAGACAGTGAGACTACCAAGGGAAGCTACTCTTTGTCTGTGAGAGACAGCGACCATCAGGCTGACACTGTCAAGCATTATAAGATCCGCACACTGGATAACGGCGGTTTCTATATTTCCCCGCGAATCACATTCAACACCCTGCAGGACCTGGTCAGCCACTACAAAAAGCAGAGCGATGGGCTGTGCCAGTCTCTCACCTCTCCCTGTCTGAGTCCCAAACCTCAGAAGCCTTGGGAGAAAGACGCATGGGAGATTCCACGCGAGTCCCTCAAACTGGACAAACGTCTGGGAGCAGGACAGTTTGGGGAGGTCTGGATGGCAATGTACAACAAGCACACCAAAGTGGCGGTGAAGACTATGAAGCCTGGCAGTATGTCTGTGGAAGCTTTCCTTATGGAGGCCAACTTAATGAAAAGCCTACAGCACGACAAACTGGTCCGTCTCAACGCTGTGGTCACCAAAGAAGAGCCCATTTACATCATTACAGAGTTCATGGAGAAAGGCAGTTTACTGGACTTCATTAAAAGCGACGAAGGGAACCGAGTCCAGCTGCCCAAACTGATCGACTTCTCAGCACAGATTGCAGAAGGTATGGCTTACATTGAGCAGAGGAACTACATTCACAGAGATCTCCGTGCTGCCAACATCCTGGTCAACAAAAGTTTAGTGTGTAAGATTGCTGATTTTGGACTGGCACGTATCATAGAGGACAACGAATACACTGCTAGAGAAGGTGCAAAGTTCCCTATTAAGTGGACAGCTCCAGAGGCTATAAACTATGGCTCCTTCACCATCAAATCCGATGTGTGGTCTTTCGGCATCCTGCTGACTGAAATCATTAGCTATGGCCGCACGCCATACCCAGgGATGACCAACCCCGAGGTAATCCGTGCTCTTGAGAGAGGTTACCGCATGCAGCGTCTGGACTCCTGTCCTCAAGAGCTCTACGACATCATGCTAGAGTGCTGGAAGAACAAGCCTGAGGACAGACCCACCTTTGAGTACCTGCAGAGCGTGCTGGAGGACTTTTACACTGCCACCGAGAGCCAGTATCAGCAACAACcttga

Function

symbol description
hck Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within protein phosphorylation. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Orthologous to human HCK (HCK proto-oncogene, Src family tyrosine kinase).

GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:0042127 regulation of cell population proliferation biological_process
GO:0030154 cell differentiation biological_process
GO:0038083 peptidyl-tyrosine autophosphorylation biological_process
GO:0006468 protein phosphorylation biological_process
GO:0016310 phosphorylation biological_process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biological_process
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function
GO:0004715 non-membrane spanning protein tyrosine kinase activity molecular_function

KEGG:

id description
ko04666 Fc gamma R-mediated phagocytosis
ko04062 Chemokine signaling pathway
ko05167 Kaposi sarcoma-associated herpesvirus infection
ko01001 Protein kinases
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-090313-72 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within protein phosphorylation. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Orthologous to human HCK (HCK proto-oncogene, Src family tyrosine kinase).

Ensembl:

ensembl_id ENSDARG00000058647

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00042682 False 7256 mRNA 0.39 13 7505943 7545960
TCONS_00042683 True 1470 mRNA 0.50 11 7518294 7540612

Neighbor

gene id symbol gene type direction distance location
XLOC_021473 rbbp8l coding upstream 1926 7471072 ~ 7504017 (+)
XLOC_021472 NA coding upstream 70627 7402807 ~ 7435316 (+)
XLOC_021471 gata5 coding upstream 114915 7379728 ~ 7391028 (+)
XLOC_021470 si:dkeyp-73a2.2 coding upstream 150163 7350170 ~ 7355780 (+)
XLOC_021469 NA coding upstream 299748 7204539 ~ 7206195 (+)
XLOC_021475 tm9sf4 coding downstream 2837 7548797 ~ 7578892 (+)
XLOC_021476 pofut1 coding downstream 146082 7692042 ~ 7709134 (+)
XLOC_021477 kif3b coding downstream 164487 7710447 ~ 7736719 (+)
XLOC_021478 rgs19 coding downstream 1133256 8679216 ~ 8699993 (+)
XLOC_021479 NA coding downstream 1242035 8787995 ~ 8811654 (+)
XLOC_021467 NA non-coding upstream 639987 6851931 ~ 6865956 (+)
XLOC_021466 BX005466.1 non-coding upstream 680141 6825688 ~ 6825802 (+)
XLOC_021488 CU137717.1 non-coding downstream 1761614 9307574 ~ 9308561 (+)
XLOC_021490 NA non-coding downstream 1850708 9396668 ~ 9403617 (+)
XLOC_021493 CR388392.1 non-coding downstream 2072253 9618213 ~ 9618335 (+)
XLOC_021494 CU466281.1 non-coding downstream 2181450 9727410 ~ 9727432 (+)

Expression


Co-expression Network