XLOC_021509 (edn3b)


Basic Information

Item Value
gene id XLOC_021509
gene name edn3b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 12072980 ~ 12106839 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00042742
AAAAAGTCTTTTCCAACAGGGTTGTTTTCAGATTTTGATGAGGATGCTCAGAactattttttttgactgaaatggatttgttttggaaaacatttttcatttagaAACCCGGAAACCGCATCTGACAACTTTTTTCCCCCCACAAATTGGTCTCGAGCACAATAATAAGGACGCTATTAAAATGGCTAAACTGATTCCTGATGCACTTTTGCTAATTGTGAGTTTGATAAACATTTTCACCGTGGATACATCGTTTTCCAGTGAGGGAGACTTGCACTCATCTCCAGTCTTCTCTGGTGGTTCCAGCAGTGTTGGACATCAGCAGAAAGAAGCGAAGCTTGTTTCAGCATCACACGCTCACACAAGATCCAAGCGCTGCACTTGCTACTCTTTCAAAGACAGAGAATGTGTTTATTACTGTCATTTGGGCATCATCTGGATCAACACCCCACAACGTACAGTTCCATACGGCATGTCAAGTTATCGCAGCCCTCAGAGATTAAGGCGCTCCAGCGGGACTATATCAGTGGTTCTTCGTCGCTGCTTATGCACAGACCATAATGATGTCCATTGCTACAACTTCTGTGATGCAAGCTCCGAGAATGTGTCAGAGGGAAGATTGAGAGGACGTTCACCTTGGTAAGACCACTGGCTTCTTGTCACACCTCCAGCCTCAGAAATCAGGACTGATGATCAGCATCAAACCGGGCATCTAACTAGGTACAGGTTTTGGATTTTTACAGATTTGGAGTAAAAGCTACCCCACATTCCTCAGCGTGTTATATTTCCTGGAACGTCCTTGACTCATCTGGTCCACGGTAACAAGTGAATTCCTTAGAAAACTCTTTGCAGATTTCGGAAGCATATCTGTGTGGGACGCACGTCCTTGCTTCAAGGGTTACGTCCAGTTGACTTTACATTGACATTTTAACAAATGCGAATACTCAGTGGACGTCCTTGGATTCGGGAGCCTTGCAGGTCTGGAATCAGATCTTTAAAATACTCTATGCATTATCTCCACTTTGTGGGCAGATTTTCAGACGGATAAAGTGAGTCTTGAATTCTTCACTTTGCCTGATTGCAGAAAATAATATGTTCAATGTTGTTATTGTGAATGaactgagaaaaaaaagtttCCTGAGAGAAAGATTGCCAGATTAACcgctacaatttttttttaacctccTAAACATATCCTTTCTGATTTTGCTCACTCAAGCAAAATGTTTTTCCTCTGCACAACaagttttgacattttattttctcc

Function

symbol description
edn3b Predicted to enable endothelin B receptor binding activity and hormone activity. Acts upstream of or within melanocyte differentiation and pigment cell development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in epidermis. Human ortholog(s) of this gene implicated in Hirschsprung's disease; Waardenburg syndrome type 4B; Waardenburg's syndrome; and congenital central hypoventilation syndrome. Orthologous to human EDN3 (endothelin 3).

GO:

id name namespace
GO:0019229 regulation of vasoconstriction biological_process
GO:0003100 regulation of systemic arterial blood pressure by endothelin biological_process
GO:0014826 vein smooth muscle contraction biological_process
GO:0070285 pigment cell development biological_process
GO:0030318 melanocyte differentiation biological_process
GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity biological_process
GO:0006874 cellular calcium ion homeostasis biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005179 hormone activity molecular_function
GO:0031708 endothelin B receptor binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090313-235 Predicted to enable endothelin B receptor binding activity and hormone activity. Acts upstream of or within melanocyte differentiation and pigment cell development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in epidermis. Human ortholog(s) of this gene implicated in Hirschsprung's disease; Waardenburg syndrome type 4B; Waardenburg's syndrome; and congenital central hypoventilation syndrome. Orthologous to human EDN3 (endothelin 3).

Ensembl:

ensembl_id ENSDARG00000086669

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00042742 True 1267 mRNA 0.42 4 12072980 12106839

Neighbor

gene id symbol gene type direction distance location
XLOC_021508 CR735125.1 coding upstream 137280 11935584 ~ 11935700 (+)
XLOC_021507 cntn3a.1 coding upstream 211587 11669109 ~ 11861393 (+)
XLOC_021506 chl1a coding upstream 620668 11285662 ~ 11452312 (+)
XLOC_021505 NA coding upstream 848375 11224124 ~ 11224605 (+)
XLOC_021504 ppp4r2a coding upstream 1245561 10805188 ~ 10827419 (+)
XLOC_021511 ttll9 coding downstream 28000 12134839 ~ 12150667 (+)
XLOC_021512 ppp1r3da coding downstream 54061 12160900 ~ 12162754 (+)
XLOC_021513 sycp2 coding downstream 91403 12198242 ~ 12228363 (+)
XLOC_021514 NA coding downstream 152697 12259536 ~ 12279048 (+)
XLOC_021515 pigt coding downstream 255060 12361899 ~ 12414082 (+)
XLOC_021503 BX323028.1 non-coding upstream 1466434 10601324 ~ 10606546 (+)
XLOC_021497 NA non-coding upstream 2120154 9938245 ~ 9952826 (+)
XLOC_021495 NA non-coding upstream 2207042 9865701 ~ 9865938 (+)
XLOC_021518 NA non-coding downstream 566564 12673403 ~ 12830266 (+)
XLOC_021519 NA non-coding downstream 568088 12674927 ~ 12675421 (+)
XLOC_021520 NA non-coding downstream 592132 12698971 ~ 12700414 (+)
XLOC_021525 CR749171.1 non-coding downstream 1335769 13442608 ~ 13442722 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000021_02522404_02530893 NA coding CI01000021 null 2522053 ~ 2530893 (-)