XLOC_021531 (lmod3)



Basic Information


Item Value
gene id XLOC_021531
gene name lmod3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 13814978 ~ 13822642 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00042772
ACTTGTTCCATAAATACCATCCCCTCAGTTGAATGGAGGTTATTTTAGATCGTACATGTGGCGTAAGGCCTTGAGTCCTCCTGCTTGTCTGGAACTAAGTGACACCACACTTTAGAGGCAGTGGCTGTAACTGAGTTCTTGAAAACACAGAAGTGGACATGTCTGAGCGCACTGAACAGGAATCATACACAGACAAAATCGATGAGGATGAGATTCTGGCAGGCCTCTCGGCGGAGGAGCTCAAACAGCTCCAAAGTGAGATGGACGACATCGCTCCTGACGAGAGAGTGCCGGTGGGATTGAGACAGAAAGACGCTTCTCATGAGATGACAGTCCGAGATTGCACTGAGCCTGAATCAGAAGAGGAGATAGATGAGGATGAAATTCTGGCAGGCCTCTCAGCAGAGGAGCTCAAGCAGCTCCAGAGCGAGATGGAAGAAATTGCTCCTGACGAGAGAGTGCCGGTGGGAATGAGACAGAGAGACCAAACTGACAAACCACCCACTGGATCATTTGATCACAGATCGCTGGTGGAATATCTGTACTGGGAGAAAGAGTCCAAACGCATGCTGGAGGAAGAGAGGGTTCCCACAACTCTATTACCCAGTCAGaaaacaaatgaggaGCATGAAGCAAAAAATGAAGACAAAGTTGAAGAGCTGGAACTTGTCTATGAGGAGATTGTGGAGGAGGTTGAAGGGGGACAGGGAGATGCTGTTGTTGATGAAGTGATTGAAGAAGTGATAATGGAAGTTGAGGAAGAGGACAAAGTATGTGACAAGCCTGTCAAAACAGATCTTGATGCTACCGACCCCACAGTGACCTCAGAAGATGGTTTACAGCGCCCTTCAGAGTCTGCAGATGCAAATGTTGAAGCTAAGACTGACCAATCAGGACTTGACACAGAAACTAAAGTAAATGAGGAGAAGAAAGAAGATTCCACTGAACCTGCTCCCTCATCATATGAAAATTGGGTTCCAGAGAAAGAAGAAAGGGTCATATCCAAGCTAAAGATCCCAAAACTTGCTCTAGGTGGCAACACTTTTGTTAAAAAGACTGCAAGGCCTTCTGGGAATGAAACTAATTTGGAGTCCACTCTGGATAAAATTCGCAACAACAATCCCTCTGTCACAGACGTCAATCTAAACAATATTGAAAACATTCCAAAAGAAATGCTCCTTGATTACGTCAACTCCCTGAAGAAGAACCGACATGTTAAGACCTTTAGCATTGCAAACACTGGCGCAGATGAAAATGTAGCATTCACTCTTGCTAACATGCTTAAAGAGAACAGGAGTATCACCACACTAAATATCGAATCCAATTTCATCACAGGAAAAGGAATTGTGGCAATAATACGTTGCCTGCAGTTCAACGAGACATTAACTGAGCTTCGCTTCCACAATCAAAGGCACATGCTAGGACACCATGCAGAAATGGAGGTATCTCGTCTCCTTAAGGCTAACAACACTCTTCTGAAGATGGGTTACCATTTTGAACTCCCTGGGCCCAGAATGGTGGTCACCAATCTCCTCACTAGGAACTTGGATCGTCAACGGCAACAGAGAATGGAGGAGCAGAAGCTCCAGCAAATGAAAGAGCAGAGGAAGGTCATGGAGATGTACGAAGACTCTCTAAACTTGCCCCCTGGCATGTTGGAAATGTTGGGAGGCTACATACCATTGTCCCTCTTGCAGAATTGTCAAAATGGGGCTGAGGATATCCCTGAAGATTCTCCTGAACCTTCACCACAACCAAGTCCACCTCACCAGCTGTGCAAAACCCAACATCTTGCCCCACAACAGCATCCTCCAAATTTAAGTACAGGAAACCTCTTCGAAGAAGTACAGCTGAAAAAGACTCCAAAACGAAGAGATCCACTTCTGGAATGGAACCAATGTGATGAGAGGAAAGATGGAAGACCCAATGTTCATCTAAGGAGCGTTCCTAAAAAAAGGAGCATAGCAAGAGAAGGACCTGTGGATGAAAGAGCAAACCTAAAAGACATGATTAAGACGTTAAAGCCAGTTCCGCGTAGGCGAGAGCCACCAAAGGTGGACTTAACACCCCGGGATCACCTGCTCAGTGAGATTCGACAGAGCAATGTGGCCTATCTCAAAGCAGTACCTCTTCCTAAAATCCTGGAGTCACAGGAAACTAGTCTCTTTTGAGACACACACATAACTTCAAATAGATTGCACAGTGGGACAGGGCCAACGTCAGACAGACCATGGAGAGAATGCGGCTCATGTGGCCAAAC

Function


symbol description
lmod3 Predicted to enable tropomyosin binding activity. Acts upstream of or within muscle contraction and skeletal muscle thin filament assembly. Predicted to be located in M band. Predicted to be active in striated muscle thin filament. Human ortholog(s) of this gene implicated in nemaline myopathy 10. Orthologous to human LMOD3 (leiomodin 3).

GO:

id name namespace
GO:0048741 skeletal muscle fiber development biological_process
GO:0051694 pointed-end actin filament capping biological_process
GO:0006936 muscle contraction biological_process
GO:0007015 actin filament organization biological_process
GO:0030239 myofibril assembly biological_process
GO:0030240 skeletal muscle thin filament assembly biological_process
GO:0005856 cytoskeleton cellular_component
GO:0005865 striated muscle thin filament cellular_component
GO:0030016 myofibril cellular_component
GO:0031430 M band cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005523 tropomyosin binding molecular_function
GO:0003785 actin monomer binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090313-353 Predicted to enable tropomyosin binding activity. Acts upstream of or within muscle contraction and skeletal muscle thin filament assembly. Predicted to be located in M band. Predicted to be active in striated muscle thin filament. Human ortholog(s) of this gene implicated in nemaline myopathy 10. Orthologous to human LMOD3 (leiomodin 3).

Ensembl:

ensembl_id ENSDARG00000062662

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00042772 True 2260 mRNA 0.46 4 13814978 13822642

Neighbor


gene id symbol gene type direction distance location
XLOC_021530 zbtb46 coding upstream 8483 13721826 ~ 13806495 (+)
XLOC_021529 NA coding upstream 158659 13656035 ~ 13656319 (+)
XLOC_021528 NA coding upstream 189447 13624913 ~ 13625531 (+)
XLOC_021527 dre-mir-1388 coding upstream 210658 13604218 ~ 13604320 (+)
XLOC_021526 uckl1b coding upstream 214974 13528053 ~ 13600004 (+)
XLOC_021532 NA coding downstream 21915 13844557 ~ 13850492 (+)
XLOC_021533 NA coding downstream 105697 13928339 ~ 13941278 (+)
XLOC_021534 cacnb3a coding downstream 274866 14097508 ~ 14180307 (+)
XLOC_021535 birc7 coding downstream 394866 14217508 ~ 14230506 (+)
XLOC_021536 NA coding downstream 411083 14233725 ~ 14235007 (+)
XLOC_021525 CR749171.1 non-coding upstream 372256 13442608 ~ 13442722 (+)
XLOC_021520 NA non-coding upstream 1114564 12698971 ~ 12700414 (+)
XLOC_021539 CR388373.1 non-coding downstream 645361 14468003 ~ 14470571 (+)
XLOC_021542 CR759764.1 non-coding downstream 1530491 15353133 ~ 15353249 (+)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000021_01288735_01291953 LMOD3 coding CI01000021 null 1288596 ~ 1291962 (+)