Item | Value |
---|---|
gene id | XLOC_022419 |
gene name | acvrl1 |
gene type | coding |
species | zebrafish (Danio rerio) |
category of species | model fish |
Item | Value |
---|---|
chromosome id | NC_007134.7 |
NCBI id | CM002907.2 |
chromosome length | 46223584 |
location | 27835647 ~ 27857104 (-) |
genome version | GRCz11_2017_zebrafish_Genome |
symbol | description |
---|---|
acvrl1 | Predicted to enable SMAD binding activity and transforming growth factor beta receptor activity, type I. Acts upstream of or within several processes, including artery morphogenesis; blood vessel endothelial cell migration; and determination of ventral identity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of BMP receptor complex. Predicted to be active in plasma membrane. Is expressed in cardiovascular system and liver. Used to study arteriovenous malformation. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia and pulmonary hypertension. Orthologous to human ACVRL1 (activin A receptor like type 1). |
id | name | namespace |
---|---|---|
GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | biological_process |
GO:0007179 | transforming growth factor beta receptor signaling pathway | biological_process |
GO:0007507 | heart development | biological_process |
GO:0048514 | blood vessel morphogenesis | biological_process |
GO:0071363 | cellular response to growth factor stimulus | biological_process |
GO:0001525 | angiogenesis | biological_process |
GO:0048264 | determination of ventral identity | biological_process |
GO:0030509 | BMP signaling pathway | biological_process |
GO:0048844 | artery morphogenesis | biological_process |
GO:0006468 | protein phosphorylation | biological_process |
GO:0001568 | blood vessel development | biological_process |
GO:0009953 | dorsal/ventral pattern formation | biological_process |
GO:0097746 | blood vessel diameter maintenance | biological_process |
GO:0016310 | phosphorylation | biological_process |
GO:0001944 | vasculature development | biological_process |
GO:0034405 | response to fluid shear stress | biological_process |
GO:0060840 | artery development | biological_process |
GO:0043534 | blood vessel endothelial cell migration | biological_process |
GO:0005886 | plasma membrane | cellular_component |
GO:0016020 | membrane | cellular_component |
GO:0016021 | integral component of membrane | cellular_component |
GO:0070724 | BMP receptor complex | cellular_component |
GO:0043235 | receptor complex | cellular_component |
GO:0016740 | transferase activity | molecular_function |
GO:0005524 | ATP binding | molecular_function |
GO:0046332 | SMAD binding | molecular_function |
GO:0000166 | nucleotide binding | molecular_function |
GO:0004672 | protein kinase activity | molecular_function |
GO:0004674 | protein serine/threonine kinase activity | molecular_function |
GO:0004675 | transmembrane receptor protein serine/threonine kinase activity | molecular_function |
GO:0016301 | kinase activity | molecular_function |
GO:0005025 | transforming growth factor beta receptor activity, type I | molecular_function |
id | description |
---|---|
ZDB-GENE-021003-1 | Predicted to enable SMAD binding activity and transforming growth factor beta receptor activity, type I. Acts upstream of or within several processes, including artery morphogenesis; blood vessel endothelial cell migration; and determination of ventral identity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of BMP receptor complex. Predicted to be active in plasma membrane. Is expressed in cardiovascular system and liver. Used to study arteriovenous malformation. Human ortholog(s) of this gene implicated in hereditary hemorrhagic telangiectasia and pulmonary hypertension. Orthologous to human ACVRL1 (activin A receptor like type 1). |
ensembl_id | ENSDARG00000018179 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
TCONS_00044227 | False | 2794 | mRNA | 0.44 | 11 | 27835647 | 27857051 |
TCONS_00044228 | True | 2321 | mRNA | 0.45 | 11 | 27835653 | 27857104 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
XLOC_022418 | acvr1ba | coding | downstream | 12727 | 27800519 ~ 27822920 (-) |
XLOC_022417 | NA | coding | downstream | 39724 | 27788369 ~ 27795923 (-) |
XLOC_022416 | NA | coding | downstream | 63275 | 27770481 ~ 27772372 (-) |
XLOC_022415 | NA | coding | downstream | 106193 | 27727295 ~ 27729454 (-) |
XLOC_022414 | dnajc22 | coding | downstream | 133086 | 27696694 ~ 27702561 (-) |
XLOC_022420 | ankrd33aa | coding | upstream | 5703 | 27862807 ~ 27875140 (-) |
XLOC_022421 | sp5l | coding | upstream | 165987 | 28023091 ~ 28025943 (-) |
XLOC_022422 | b4galnt1a | coding | upstream | 240178 | 28097282 ~ 28123767 (-) |
XLOC_022423 | tac3a | coding | upstream | 282385 | 28139489 ~ 28141419 (-) |
XLOC_022424 | znf385a | coding | upstream | 328779 | 28185883 ~ 28294763 (-) |
XLOC_022412 | NA | non-coding | downstream | 160253 | 27652896 ~ 27675394 (-) |
XLOC_022408 | CR354381.1 | non-coding | downstream | 255355 | 27580164 ~ 27580292 (-) |
XLOC_022427 | NA | non-coding | upstream | 576071 | 28433175 ~ 28453703 (-) |
XLOC_022432 | CR677617.1 | non-coding | upstream | 1328748 | 29185852 ~ 29257716 (-) |
XLOC_022433 | NA | non-coding | upstream | 1476749 | 29333853 ~ 29358214 (-) |
XLOC_022440 | NA | non-coding | upstream | 1817891 | 29674995 ~ 29706359 (-) |
XLOC_022443 | NA | non-coding | upstream | 1964097 | 29821201 ~ 29822565 (-) |
species | gene id | symbol | gene type | chromosome | NCBI id | location |
---|---|---|---|---|---|---|
grasscarp (Ctenopharyngodon idella) | CI01000001_10658398_10672912 | ACVRL1 | coding | CI01000001 | null | 10658392 ~ 10673477 (-) |