alad (hem2)



Basic Information


Item Value
gene id alad
gene name hem2
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information


Item Value
chromosome id NC_048569.1
NCBI id CM023223.2
chromosome length 100798064
location 29045103 ~ 29055942 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence


>XM_021602368.2
TTTTTCGTAATATTTTCCTTCCTTCACTGAGATAGTGTACAATCGCGAGAATTTGTACGTTCACGGAATTTACGGTGGCCGGTTAGTGCGTGAGACTAGTGCAAGCGAAAGCCAATGAGCAAGGACGTACTGTACAAGggcAAAGATGCAACCCGTCGAGTCTCTCCTCCACAGTGGCTATTTCCACCCAACACTCAGATACTGGCAGACCTGTGCCTCAGACTTGAGACCTGAGAACCTCATCTACCCCATCTTCATCACTGACAGCCCTGATGCTGTGGAGCCCATCGCTAGTCTACCTGGCCAGGCCAGATATGGAGTGAATAAACTGGAGGGCATGCTACGCCCCCTTGTGGAAAAGGGCTTGAAGTGTGTGCTGATTTTCGGAGTGCCTGCAAAAATAGCTAAGGATGAGAGAGGTTCGGGTGCAGACACAGACAATACTCCGGCTGTGTTGGCTGTGAAGAAGATAAAGTCTCTTTTCCCTGACCTGCTGATGGCCTGTGACGTCTGCCTCTGTCCCTACACCTCACATGGACACTGTGGAATCTTGCGGGAGGATGGCACTCTGGACAATGGTGCCAGTTGCCAACGTTTGGCAGAAGTGGCATTGGCCTATGCCCGCGCTGGCTGTCACATCATTGCACCCTCTGATATGATGGATGGGCGAGTGGGAGCTATCAAACATTCACTGATGTCTAATGACATGGGCAACAAGgTGTCAGTGCTGAGTTACAGTGCCAAGTTTGCTTCCTGTTACTATGGTCCCTTCAGagATGCAGCACAGTCCAAGCCAGCATTTGGAGATAGGCGCTGTTATCAGCTGCCCTCCGGTGCAAGGGGCCTGGCACTACGAGCTGTGGACAGAGATGTCAAGGAGGGAGCAGATATGCTGATGGTGAAGCCAGGACTGCCCTATCTGGACATAGTGAGGGAGGTCAAAGACAAGCACCCCACTCACCCACTGGCAGTGTATAATGTGTCAGGGGAATTTGCCATGCTGTGGCATGGGGCCCAGGCTGGAGCTTTTGACCTGCGCACCGCTGTACTGGAGTCTATGACTGCCTTCCGCAGGGCAGGTGCTGACATCATCATCACCTACTATACACCTCAACTGCTCACCTGGCTGAAAGAGTAACAGACAGAAGGATGGACATAAAGATGGATCATGTGACAAACTCCTTTTTACCTAGCTGTGCAAGGCTGACCTACACTGACAAATGGTGTCTATTCAAACCAAACTGACATGTGAGAACAGGCAATCTATCTTCATACATTAATTTACAGTTTATTTTTCTATATAACATTGTTACGtcatattgttttttttctttgtgtgCAGCAACCACTAATTCTCACCAAAGGTGGGAGTCTTGGCGCTAGTAGACACATATGTAAAGCGTATCAAATTCGCTTTGAAGGGTTTGTCTGTTAGATGAAAGAATGgtaatataaaatatgttgattTTGTTTTATGGGCATTATTTACTATTCTATAGTTTTCTAAATAGAGTATCAAGAATATAGGCCTTGACTTGTTATAGCTCTGTGACGTCTGTAATAGCTCTGGCTTTAGCGCTGACATTTAGCAGTGGTTGTAAGGTTGGGTCAAGAAACCTGTAAAGATCTTTTTTTACCAGGGTAAATGGTCCTGACCCAGAAAATAGAGATTTGTTAGATAACAGCAATAAAGCTacaatcaagtctgaaa
>XM_021602367.2
GTATGTTAGTTTATGCTGCTAAATTACGTTTTGGATGTTGCAAGggcAAAGATGCAACCCGTCGAGTCTCTCCTCCACAGTGGCTATTTCCACCCAACACTCAGATACTGGCAGACCTGTGCCTCAGACTTGAGACCTGAGAACCTCATCTACCCCATCTTCATCACTGACAGCCCTGATGCTGTGGAGCCCATCGCTAGTCTACCTGGCCAGGCCAGATATGGAGTGAATAAACTGGAGGGCATGCTACGCCCCCTTGTGGAAAAGGGCTTGAAGTGTGTGCTGATTTTCGGAGTGCCTGCAAAAATAGCTAAGGATGAGAGAGGTTCGGGTGCAGACACAGACAATACTCCGGCTGTGTTGGCTGTGAAGAAGATAAAGTCTCTTTTCCCTGACCTGCTGATGGCCTGTGACGTCTGCCTCTGTCCCTACACCTCACATGGACACTGTGGAATCTTGCGGGAGGATGGCACTCTGGACAATGGTGCCAGTTGCCAACGTTTGGCAGAAGTGGCATTGGCCTATGCCCGCGCTGGCTGTCACATCATTGCACCCTCTGATATGATGGATGGGCGAGTGGGAGCTATCAAACATTCACTGATGTCTAATGACATGGGCAACAAGgTGTCAGTGCTGAGTTACAGTGCCAAGTTTGCTTCCTGTTACTATGGTCCCTTCAGagATGCAGCACAGTCCAAGCCAGCATTTGGAGATAGGCGCTGTTATCAGCTGCCCTCCGGTGCAAGGGGCCTGGCACTACGAGCTGTGGACAGAGATGTCAAGGAGGGAGCAGATATGCTGATGGTGAAGCCAGGACTGCCCTATCTGGACATAGTGAGGGAGGTCAAAGACAAGCACCCCACTCACCCACTGGCAGTGTATAATGTGTCAGGGGAATTTGCCATGCTGTGGCATGGGGCCCAGGCTGGAGCTTTTGACCTGCGCACCGCTGTACTGGAGTCTATGACTGCCTTCCGCAGGGCAGGTGCTGACATCATCATCACCTACTATACACCTCAACTGCTCACCTGGCTGAAAGAGTAACAGACAGAAGGATGGACATAAAGATGGATCATGTGACAAACTCCTTTTTACCTAGCTGTGCAAGGCTGACCTACACTGACAAATGGTGTCTATTCAAACCAAACTGACATGTGAGAACAGGCAATCTATCTTCATACATTAATTTACAGTTTATTTTTCTATATAACATTGTTACGtcatattgttttttttctttgtgtgCAGCAACCACTAATTCTCACCAAAGGTGGGAGTCTTGGCGCTAGTAGACACATATGTAAAGCGTATCAAATTCGCTTTGAAGGGTTTGTCTGTTAGATGAAAGAATGgtaatataaaatatgttgattTTGTTTTATGGGCATTATTTACTATTCTATAGTTTTCTAAATAGAGTATCAAGAATATAGGCCTTGACTTGTTATAGCTCTGTGACGTCTGTAATAGCTCTGGCTTTAGCGCTGACATTTAGCAGTGGTTGTAAGGTTGGGTCAAGAAACCTGTAAAGATCTTTTTTTACCAGGGTAAATGGTCCTGACCCAGAAAATAGAGATTTGTTAGATAACAGCAATAAAGCTacaatcaagtctgaaa

Function


symbol description
hem2 Enables porphobilinogen synthase activity and zinc ion binding activity. Involved in heme biosynthetic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in porphyria cutanea tarda and sickle cell anemia. Orthologous to human ALAD (aminolevulinate dehydratase).

NR:

description
delta-aminolevulinic acid dehydratase-like

GO:

id name namespace
GO:0006779 porphyrin-containing compound biosynthetic process biological_process
GO:0046872 metal ion binding molecular_function
GO:0004655 porphobilinogen synthase activity molecular_function

KEGG:

id description
K01698 hemB, ALAD; porphobilinogen synthase

RNA


RNA id representative length rna type GC content exon number start site end site
XM_021602368.2 False 1711 mRNA 0.47 12 29045103 29055942
XM_021602367.2 True 1617 mRNA 0.47 12 29045267 29055942

Neighbor


gene id symbol gene type direction distance location
ssna1 ssna1 coding upstream 35993 29004767 ~ 29009110 (+)
spag8 LOC106566715 coding upstream 113693 28926263 ~ 28931410 (+)
LOC110523559 LOC106566708 coding upstream 164960 28876573 ~ 28880143 (+)
zfand5b zfand5b coding upstream 207914 28829715 ~ 28837189 (+)
smc5 smc5 coding upstream 215675 28805226 ~ 28829428 (+)
LOC110522906 LOC106563306 coding downstream 5333 29061275 ~ 29067123 (+)
coq4 coq4 coding downstream 33583 29089525 ~ 29097342 (+)
LOC110523572 zmynd19 coding downstream 60549 29116491 ~ 29121227 (+)
tmem141 tmem141 coding downstream 77902 29133844 ~ 29135483 (+)
LOC110523574 LOC106566787 coding downstream 84891 29140833 ~ 29166510 (+)
G386568 LOC106566731 non-coding upstream 49980 28994145 ~ 28995123 (+)
G386537 NA non-coding upstream 79455 28961817 ~ 28965648 (+)
G386445 NA non-coding upstream 191952 28852880 ~ 28853151 (+)
G386065 NA non-coding upstream 274536 28756510 ~ 28770567 (+)
G386606 NA non-coding downstream 14870 29070812 ~ 29073163 (+)
LOC110523576 LOC106563296 non-coding downstream 118406 29174319 ~ 29187968 (+)
G386814 NA non-coding downstream 140945 29196887 ~ 29197098 (+)
G386815 NA non-coding downstream 141189 29197131 ~ 29197363 (+)
G386846 NA non-coding downstream 220859 29276801 ~ 29277657 (+)
G385805 NA other upstream 627548 28416605 ~ 28417555 (+)
G385171 LOC106566130 other upstream 1140372 27904467 ~ 27904731 (+)
G385053 NA other upstream 1338025 27706714 ~ 27707078 (+)
LOC110522888 LOC106566402 other upstream 1361710 27675352 ~ 27719165 (+)
tbx5a LOC106566939 other downstream 685858 29741800 ~ 29763439 (+)
G387516 NA other downstream 841044 29896986 ~ 29898134 (+)
G388019 NA other downstream 1231009 30286951 ~ 30287824 (+)
G390184 NA other downstream 2904413 31960355 ~ 31960745 (+)
G390393 NA other downstream 3164239 32220181 ~ 32220533 (+)

Expression



Co-expression Network