si:dkey-88e18.2 (il12b)


Basic Information

Item Value
gene id si:dkey-88e18.2
gene name il12b
gene type coding
species rainbow trout (Oncorhynchus mykiss)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_048570.1
NCBI id CM023224.2
chromosome length 101096859
location 47110812 ~ 47119011 (+)
genome version USDA_OmykA_1.1_2020_rainbow_trout_Genome

Sequence

>XM_036979106.1
atgcacacacagttcTACTAGTACTAATAGTTTACTTATGAATTGCACCCAACTTCATCCTCCCCCAAATCCCCACCCACCCTCTAATCTTCCAAAAGTCCGTGGCAAAGATGTGTGGGCAGAGGCTGAATAGCACACAGTAGCCAAACATATAAAACAGAAGGACTTTCAGAAAATTAGAGAAACTCAAGTTGACTCTTTGTTACAAGCTTGACCGAGCAGACTGCCAACAATTTATCAACGTGACCAGCGCAACTTCAGCATAACGATGACTGTAGTACCATGGCTCATCATGCTCCTCTGTGTTATTCTACCGACAGTGAATGGTCTCACCTCCTTCCATGaactctACATGGTTGATAAGGGGGACAGTTTGGTGACTCTGACATGTCCCACGGCATTCTCTGGAGCTATGACGTGGAAGTAcgagggagagactgaggatTTAGACAAAACTCTGGTCCAAGGCCGTAACCTGATACTGAATGAGGTGGACTGGTATGGAGAATACAGCTGCTGGGATGGAGACAAGAAACTAGGATCCATCTATCTACTGGAGGAGCTGAAGAACCCAGAcgacgATGATTTAATCAGCTGTCGGGCCAAGTCTTATGGCTGCACCTTTAACTGTAGCTGGACCCACAGTGAATTCACAGCTGTCCGTCTTGGGCTGGGCAATGACTGTACTGACAGCCAGGAATCTTGCACCTGGGTGTACCCAACGACCAGCCTCCAAGATGGAGGGTTGGAGTTTGAACTGACACATTCGCTTTCACCCTACACTGAGGAGGCCGCTCCTCTAGTGGTCACTGTTGAGGCCATCACCAGGCAGGATTACCTCAGGAAGACTAAGAGGTTCTACCTACACGACATTGTCCAGCCAGACAGTCCTGCAGGGATGAAGTGCCAGGTGATGGATCAGAGATTGAAGGTGAAAGTAGAACCGCCAGCCACCTGGAACTGTCCACCCAGCTACTTCCCTCTGGAGCACCAGATAGGATACATTTTTAAAGACAACGGAaagGAGGAGCACTCTACGAATCCTCTCATACCGAGAGGGGTCAGTAAGCTGAGGGCCCGCTCCAGAGACCCCCTGGTCCCTTCCCCCTGGAGCCAGTGGACCCCCTGGAAAAATGTGGTTACGGGAGGCAAAAAGGAGGAGAAATGCAAAGAGAAACGCAAAGGAAAAGATAGCATCTGCTGCAAGACTGGAGAAAAGAAGAGAACCAAGACTAAGTCGAGATCTGCATTCACTGCTAATGAATAACGGACATCGTATTGTCGTATCACTATGTGTTTCTGGGATCTAGACAGTTAAATATGTCAATAAAATGTAATAT
>NM_001124392.1
CAACGTGACCAGCGCAACTTCAGCATAACGATGACTGTAGTACCATGGCTCATCATGCTCCTCTGTGTTATTCTACCGACAGTGAATGGTCTCACCTCCTTCCATGaactctACATGGTTGATAAGGGGGACAGTTTGGTGACTCTGACATGTCCCACGGCATTCTCTGGAGCTATGACGTGGAAGTAcgagggagagactgaggatTTAGACAAAACTCTGGTCCAAGGCCGTAACCTGATACTGAATGAGGTGGACTGGTATGGAGAATACAGCTGCTGGGATGGAGACAAGAAACTAGGATCCATCTATCTACTGGAGGAGCTGAAGAACCCAGAcgacgATGATTTAATCAGCTGTCGGGCCAAGTCTTATGGCTGCACCTTTAACTGTAGCTGGACCCACAGTGAATTCACAGCTGTCCGTCTTGGGCTGGGCAATGACTGTACTGACAGCCAGGAATCTTGCACCTGGGTGTACCCAACGACCAGCCTCCAAGATGGAGGGTTGGAGTTTGAACTGACACATTCGCTTTCACCCTACACTGAGGAGGCCGCTCCTCTAGTGGTCACTGTTGAGGCCATCACCAGGCAGGATTACCTCAGGAAGACTAAGAGGTTCTACCTACACGACATTGTCCAGCCAGACAGTCCTGCAGGGATGAAGTGCCAGGTGATGGATCAGAGATTGAAGGTGAAAGTAGAACCGCCAGCCACCTGGAACTGTCCACCCAGCTACTTCCCTCTGGAGCACCAGATAGGATACATTTTTAAAGACAACGGAaagGAGGAGCACTCTACGAATCCTCTCATACCGAGAGGGGTCAGTAAGCTGAGGGCCCGCTCCAGAGACCCCCTGGTCCCTTCCCCCTGGAGCCAGTGGACCCCCTGGAAAAATGTAACCAACTAAGATAtaataataatagaataatatatgacatttagcagatgctttttaCAGTATCACTTCATTTCTACTATCGCCCTCCAACGTAAGCTACCATTATTTCTTCAGGCACTGGTTATCATAGACTAGTGCCTTCTAATAAATATGTAAATCTGCAAAATGGTAACTATTGACATATTTATTGAATTATATACTTATCTATTTCATAATAACTATCTGAAGAAAGCTACAAAAGGGTTAACAACAACCTCTATACTGAGCACCATTGCAACTCTGGTTTACAGTGTACAAGTGTGTGATGTGATATCTGTCCCTTTATCAATGTATCTTTGTGGTGGTTTTTCTGTGTAGGCTGATGGTTTGGCTCTGTCTCTTTGTACGTCACAACTATTGCTATTAAAAGAGCTGTGAGTTTCCTGCCTCA

Function

symbol description
il12b Enables identical protein binding activity; interleukin-12 alpha subunit binding activity; and protein heterodimerization activity. Contributes to cytokine activity; growth factor activity; and interleukin-23 receptor binding activity. Involved in several processes, including positive regulation of lymphocyte proliferation; positive regulation of peptidyl-tyrosine phosphorylation; and regulation of cytokine production. Acts upstream of or within negative regulation of protein secretion. Part of interleukin-12 complex and interleukin-23 complex. Implicated in asthma; chronic obstructive pulmonary disease; immunodeficiency 29; and salmonellosis. Biomarker of anogenital venereal wart.

NR:

description
interleukin-12 beta chain precursor

GO:

id name namespace
GO:0005615 extracellular space cellular_component
GO:0005125 cytokine activity molecular_function

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
XM_036979106.1 False 1340 mRNA 0.48 8 47110812 47119011
NM_001124392.1 True 1330 mRNA 0.46 7 47111050 47117959

Neighbor

gene id symbol gene type direction distance location
LOC110526907 NA coding upstream 106460 46993596 ~ 47004352 (+)
LOC110526054 NA coding upstream 132684 46935543 ~ 46978128 (+)
LOC118964876 NA coding upstream 175535 46931084 ~ 46935277 (+)
rasgrf2b rasgrf2 coding upstream 210808 46722960 ~ 46900004 (+)
msh3 LOC106584876 coding upstream 401850 46574935 ~ 46708962 (+)
LOC110526052 hic2 coding downstream 31889 47150900 ~ 47217434 (+)
LOC118964877 NA coding downstream 276356 47395367 ~ 47398426 (+)
LOC110526909 LOC106585521 coding downstream 302230 47421241 ~ 47424219 (+)
LOC110526910 LOC106585521 coding downstream 331834 47450664 ~ 47494972 (+)
LOC118964881 LOC106585521 coding downstream 394621 47425001 ~ 47519480 (+)
G514541 NA non-coding upstream 7250 47103352 ~ 47103562 (+)
G514530 NA non-coding upstream 31932 47078673 ~ 47078880 (+)
G514461 NA non-coding upstream 69371 47040988 ~ 47041441 (+)
G514457 NA non-coding upstream 70618 47033873 ~ 47040194 (+)
G514496 NA non-coding upstream 92253 47018247 ~ 47018559 (+)
G514614 NA non-coding downstream 118481 47237492 ~ 47237777 (+)
G514628 NA non-coding downstream 136670 47255681 ~ 47256160 (+)
G514639 NA non-coding downstream 148608 47267619 ~ 47267921 (+)
G514641 NA non-coding downstream 150032 47269043 ~ 47269331 (+)
G514632 NA non-coding downstream 162489 47281500 ~ 47284426 (+)
G514499 NA other upstream 87720 47022294 ~ 47023092 (+)
G514464 NA other upstream 183098 46926842 ~ 46927714 (+)
G513745 NA other upstream 209689 46900561 ~ 46901123 (+)
G513501 NA other upstream 750227 46359956 ~ 46360585 (+)
LOC110526042 LOC106584891 other upstream 920520 46076084 ~ 46190292 (+)
G514662 LOC106597055 other downstream 184172 47303183 ~ 47329244 (+)
G514665 NA other downstream 187427 47306438 ~ 47320050 (+)
G515069 NA other downstream 830995 47950006 ~ 47952254 (+)
G515189 LOC100135962 other downstream 1432608 48532377 ~ 48587888 (+)

Expression


Co-expression Network