XLOC_024024 (cav1)


Basic Information

Item Value
gene id XLOC_024024
gene name cav1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 18563476 ~ 18577586 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00047677
ACTCTGTGCCGTGAGAGTCTTCAAGAGAGATAAACTAGCTTTCAGATAAAAGCTTGATGGGACTTTAGCATGCAGAAGAGAGGGctgttttaagggaaaaaaaactcCCCACAGAAAGCAATATCCCCACGCCTCCCACACTGCTTCCTCTGTACTGATTGTCTTGTTTCCTCACACTCATCTGATCGCACTTCAGGCACGGGACAGCATGACTAGCGGATACAAGGACGGGACACCTGAAGAGGAATACGCTCACTCGCCGTTTATCAGGAAACAGGGGAACATTTACAAACCAAACAATAAAGAAATGGATAACGACAGCATCAACGAAAAGACACTTCAGGATGTCCACACCAAGGAGATTGACCTGGTCAACCGAGACCCAAAGCATTTAAATGACGATGTGGTGAAGGTGGACTTTGAGGACGTGATCGCCGAGCCTGCCGGCACCTACAGCTTCGACGGCGTGTGGAAGGCGAGCTTCACCACCTTCACAGTAACCAAATATTGGTGCTACAGGCTGCTGACAGCGCTGGTGGGCATCCCACTCGCCCTGGTATGGGGCATCTTCTTCGCCATCCTCTCCTTCATCCACATCTGGGCCGTGGTGCCTTGCGTGAAGAGCTACCTAATCGAGATCCACTGCATCAGTCGAGTTTACTCCATCTGTGTGCACACCTTCTGCGACCCACTCTTTGAGGCCATGGGGAAATGCTTTAGTAACGTCCGGGTCACTGCTACTAAGGTGGTGTAAGGACAGAGTGAAAGAGAAGAGCCAGAGGGATCGGGTGGGATGGGGGAATGGAAACCAATGTCCAATGTTGGGAGGTAAATCAAACGTAGCCTCTGTAATAAAGAGGAAACAAAAAATGTGAGCAGAAGTGAAGGGTTGACTCTCCATTCCTGTTCAAATGCATCTGTGAGATTTGTCTACTCAGCTTTGGATTTAGGGGACGTGTGTTGAAAATCTCTAATTTTCTTTGTCATTTGTTAGCATTTATCATTGTAGGAATACTGTTTCAGCCTTACTTTTATTGTGACAGTTCATGGAAAAATGCTAATTCTTTTAAGTGTTTACTGACACTAATGTCATTCCAAATTTTCCAAGCTCCTAAAGTGCAATAATAGTGGTTTGTATGACTAGTGTGATAATTCCAAGTCTGTCAAAAACAGAGAAATGCACGTTGACCACTTTTATGGTGCTTTTGAaggtcctgtttttttttttttttttttcattttaaggcaTGGAGCTTgactattattatttgtaatggaATTTTTAGAAAAGCCATCGCTTGATCAACTGGAATATCTTTCATGAAATTCCAGATTGCATAAAAACGTATTGAAATAACTGGATTTTGGACACAATAGGCTACTTCTAATCAAATAGGTATAGGAGTTTGGAATGATATTAGATTcactaaataatgacagaatttagatttttagggtgaactatccctttaagatttgCCTGCTGGGACAAGGctgtgaatttgtgtttttattttctggttttgtttgttttatcccATTTCTATCACTGACACGTCCATTTATTCGGTCCAAAAATACTTGTAGTGTGTAAACATTACATAGTAGATTCCAGTAGTTTTGCTATGTTTATCCTTCAATTTGGGTACTATCGCCCTTTTTTGGTCATGAATGGGGTTTATGTAATCCagatattttttgtgtgtgtttttgggagAGGGTTCAGGGAATCTGAACaaattttaaaggaaaaaaaagtatGCGTGGCCCTGCTGATGTCAAGACTGCCCGTCACACTGCATGTTGCCACTAAATATGGTGGACGGCCTAAACATGGGGCCAAAGAGGTGCCCTCACTGAACCCTTTGCCAACTCAGCAAATACTAACAAAGAGACTGTTCCTGGCCCTGACATATATATAATGCTTCAACCCGGTGCTCATGGCAACAGCTTTATGAGTGGCAGAGAGTATCTTTACAACTTCCAGAGAGACATCACATGAAGCTAGCGATTAGCAAAGTCTTCCAGCAGGTCGTGAAGATTGAACTTTTCTAACACGAAAGCACATCACCACAGCCTTAACTTACACTTAAACTTTATTTGCAGTCTTTGAAGATGAAGAActtgttttaaatgttgtttcTGCTATTGACAGTGACATCATTTGGTGTGGAAATTTTGTAAGCAATCCTGTCTGCTTCTATGTTTATTCACTGTCAGACACACATGCTGCATAAAACTAAAGTTTCCAGCATCAGAGGCTGCTGCTAAAgtggggtatatatatatatatatatatatatatatatatatatatatatatatatatatagtatttcgTACTGACATTAAGCTCACCTTTTGTCTACTCGCTTTGACTCTTTCACCTCTTCGTCTACCTGCTGTCTTAAGCCCAAAATAtactttgtatttttttgtgtacATTTGCATACACGTATAGTTAAACACAAAGCCTTTCAAAGTTTGATTATGCATGATTATGCATTTGATGGCATGTGAAAACACAGATGCGCACTATAAAGAGTCCAAACATTGTGATTGATTAAATCAGAGATGCACTGATATGGAAAGTTTGGCCAACACGATAACCGATATCTCTATATAATTGGAAATGTATCAACGTATATATAACCAATATATAGGTCGACAAATACAAATCACGAATCAAATATCTGACTGCAAATatagcaacaacaaaacaaaaaacacacacaaaaaatacaaagaactactgattttattttgttatactaGCTGCCATTGtctttaaagttattaaaaatatagttACATGCTAGTTTTAAACCGATAACCGATATATAGATCAAAATGCAAAATTTAAAACGATATTCTTAGCCTAATtgcaacaaaaaacaataacaaacaaataaaaaaggactactaaatttattttatatatatatataatttatttttcttatcgGGTCGATACAGATAATATTGCAAAATAAGTAGTTATCAGCAGTTGCCAAGTTGtagccgatatattgtgcatactagacaacattttctttgtatttatttaaaacagagtTGTAGGACTCGCTTTAAGCTAATAACTGAAATATTGGTCGATAAATAAAGATTTCTATCCAAAATATTCTCAGCCTGATTgcaaaaataacattaacaatcAAATATGATAGATTTGATACAatagataaatgttttttttttttttatcaggccGATAGCGATAACATTGCTGCTGCCTAAGTACACTCGTTTTTGGCTTTGCTTTGGTGAATACTTTTTTGAATGTCGTCTTCGGTAGTTTGTTGTTCGTTTAGTATGGACACCCTGTGGACAAACTGAGTAGtgcaaaacatttcaaaatactCCTATGTATGGACTGTCATGTATGCAGAAAAACAAAGTATATTTTGGGCTTTATTGGCTGTTAACACAGAACACCTCTTTCCTTTTCTCTACACTACTTTTCATTGTTTTTCTAAGTAAACACAAGCTAGACTATTGCATGTGCGTCGTCTCATACATGAGCAAACTCTAAAAATAAGGCACTCGAGTAAATAAAAAAGCTTAAAGTTGTCTTGAGTTCTTGTGATGTTTCCCCATTTTACACCCTGCATCtcttttgctttgaaaatgtgtccTGTGTGAATGGCTACTTTAGTATCTATTGCAATGCATTTGCTTGAATGAGTCTGCCTCTCTAGATGAgatcatatttttattcatatttttatatgaaaactgaaaattctctTTCCTTGCTTTTACTGTAAAATCACTTAATGCTGTGCACATTAaagaaaatgtaatataaa
>TCONS_00047678
AGGGCTGTGCTGAGTTGCGCCCGAGTCTCCCACTCCACGCTCATGAACttcattttctgttttctttggAACCGCAGGAATACGCTCACTCGCCGTTTATCAGGAAACAGGGGAACATTTACAAACCAAACAATAAAGAAATGGATAACGACAGCATCAACGAAAAGACACTTCAGGATGTCCACACCAAGGAGATTGACCTGGTCAACCGAGACCCAAAGCATTTAAATGACGATGTGGTGAAGGTGGACTTTGAGGACGTGATCGCCGAGCCTGCCGGCACCTACAGCTTCGACGGCGTGTGGAAGGCGAGCTTCACCACCTTCACAGTAACCAAATATTGGTGCTACAGGCTGCTGACAGCGCTGGTGGGCATCCCACTCGCCCTGGTATGGGGCATCTTCTTCGCCATCCTCTCCTTCATCCACATCTGGGCCGTGGTGCCTTGCGTGAAGAGCTACCTAATCGAGATCCACTGCATCAGTCGAGTTTACTCCATCTGTGTGCACACCTTCTGCGACCCACTCTTTGAGGCCATGGGGAAATGCTTTAGTAACGTCCGGGTCACTGCTACTAAGGTGGTGTAAGGACAGAGTGAAAGAGAAGAGCCAGAGGGATCGGGTGGGATGGGGGAATGGAAACCAATGTCCAATGTTGGGAGGTAAATCAAACGTAGCCTCTGTAATAAAGAGGAAACAAAAAATGTGAGCAGAAGTGAAGGGTTGACTCTCCATTCCTGTTCAAATGCATCTGTGAGATTTGTCTACTCAGCTTTGGATTTAGGGGACGTGTGTTGAAAATCTCTAATTTTCTTTGTCATTTGTTAGCATTTATCATTGTAGGAATACTGTTTCAGCCTTACTTTTATTGTGACAGTTCATGGAAAAATGCTAATTCTTTTAAGTGTTTACTGACACTAATGTCATTCCAAATTTTCCAAGCTCCTAAAGTGCAATAATAGTGGTTTGTATGACTAGTGTGATAATTCCAAGTCTGTCAAAAACAGAGAAATGCACGTTGACCACTTTTATGGTGCTTTTGAaggtcctgtttttttttttttttttttcattttaaggcaTGGAGCTTgactattattatttgtaatggaATTTTTAGAAAAGCCATCGCTTGATCAACTGGAATATCTTTCATGAAATTCCAGATTGCATAAAAACGTATTGAAATAACTGGATTTTGGACACAATAGGCTACTTCTAATCAAATAGGTATAGGAGTTTGGAATGATATTAGATTcactaaataatgacagaatttagatttttagggtgaactatccctttaagatttgCCTGCTGGGACAAGGctgtgaatttgtgtttttattttctggttttgtttgttttatcccATTTCTATCACTGACACGTCCATTTATTCGGTCCAAAAATACTTGTAGTGTGTAAACATTACATAGTAGATTCCAGTAGTTTTGCTATGTTTATCCTTCAATTTGGGTACTATCGCCCTTTTTTGGTCATGAATGGGGTTTATGTAATCCagatattttttgtgtgtgtttttgggagAGGGTTCAGGGAATCTGAACaaattttaaagg

Function

symbol description
cav1 Enables beta-catenin binding activity. Acts upstream of or within several processes, including animal organ development; regionalization; and regulation of defense response. Predicted to be located in Golgi membrane and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; cytoplasmic vesicle; and perinuclear region of cytoplasm. Predicted to be integral component of plasma membrane. Predicted to colocalize with caveola; focal adhesion; and sarcolemma. Is expressed in several structures, including cardiovascular system; ectoderm; integument; lateral line system; and tail bud. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); lipodystrophy (multiple); primary open angle glaucoma; primary pulmonary hypertension; and systemic scleroderma (multiple). Orthologous to human CAV1 (caveolin 1).

GO:

id name namespace
GO:0060338 regulation of type I interferon-mediated signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0001756 somitogenesis biological_process
GO:0030154 cell differentiation biological_process
GO:0051480 regulation of cytosolic calcium ion concentration biological_process
GO:0070836 caveola assembly biological_process
GO:0050688 regulation of defense response to virus biological_process
GO:0048884 neuromast development biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0061026 cardiac muscle tissue regeneration biological_process
GO:0030299 intestinal cholesterol absorption biological_process
GO:0001937 negative regulation of endothelial cell proliferation biological_process
GO:0060036 notochord cell vacuolation biological_process
GO:0060038 cardiac muscle cell proliferation biological_process
GO:0061099 negative regulation of protein tyrosine kinase activity biological_process
GO:0042383 sarcolemma cellular_component
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0005794 Golgi apparatus cellular_component
GO:0000139 Golgi membrane cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0005901 caveola cellular_component
GO:0005925 focal adhesion cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0060090 molecular adaptor activity molecular_function
GO:0019901 protein kinase binding molecular_function
GO:0008013 beta-catenin binding molecular_function
GO:0044325 ion channel binding molecular_function

KEGG:

id description
ko04144 Endocytosis
ko04510 Focal adhesion
ko05205 Proteoglycans in cancer
ko05100 Bacterial invasion of epithelial cells
ko05020 Prion disease
ko05418 Fluid shear stress and atherosclerosis
ko05416 Viral myocarditis
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-030131-2415 Enables beta-catenin binding activity. Acts upstream of or within several processes, including animal organ development; regionalization; and regulation of defense response. Predicted to be located in Golgi membrane and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus; cytoplasmic vesicle; and perinuclear region of cytoplasm. Predicted to be integral component of plasma membrane. Predicted to colocalize with caveola; focal adhesion; and sarcolemma. Is expressed in several structures, including cardiovascular system; ectoderm; integument; lateral line system; and tail bud. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); lipodystrophy (multiple); primary open angle glaucoma; primary pulmonary hypertension; and systemic scleroderma (multiple). Orthologous to human CAV1 (caveolin 1).

Ensembl:

ensembl_id ENSDARG00000103747

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00047677 False 3830 mRNA 0.37 3 18563476 18577586
TCONS_00047678 True 1582 mRNA 0.41 2 18564266 18575505

Neighbor

gene id symbol gene type direction distance location
XLOC_024023 cav2 coding upstream 1681 18556588 ~ 18561795 (+)
XLOC_024022 tes coding upstream 67066 18475032 ~ 18496410 (+)
XLOC_024021 cep41 coding upstream 118197 18436301 ~ 18445279 (+)
XLOC_024020 NA coding upstream 202188 18359028 ~ 18361288 (+)
XLOC_024019 NA coding upstream 248549 18309315 ~ 18314927 (+)
XLOC_024025 met coding downstream 6291 18583877 ~ 18679071 (+)
XLOC_024026 fam185a coding downstream 134218 18711804 ~ 18721297 (+)
XLOC_024027 NA coding downstream 166435 18744021 ~ 18745029 (+)
XLOC_024028 armc10 coding downstream 300089 18877675 ~ 18889001 (+)
XLOC_024029 CR391963.2 coding downstream 307092 18884678 ~ 18885569 (+)
XLOC_023973 CR762411.1 misc upstream 3345367 15217824 ~ 15218109 (+)
XLOC_024018 NA non-coding upstream 313400 18107392 ~ 18250076 (+)
XLOC_024017 BX901919.1 non-coding upstream 465615 18097747 ~ 18097861 (+)
XLOC_024008 NA non-coding upstream 1027560 17528781 ~ 17535916 (+)
XLOC_024031 NA non-coding downstream 342957 18920543 ~ 18924391 (+)
XLOC_024040 NA non-coding downstream 778758 19356344 ~ 19362087 (+)
XLOC_024041 NA non-coding downstream 866365 19443951 ~ 19445512 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01157671_00000309_00000650 CAV1 coding CI01157671 null 309 ~ 749 (+)