XLOC_024056 (kcna1a)



Basic Information


Item Value
gene id XLOC_024056
gene name kcna1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 19954576 ~ 19958278 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00047738
CAGACCGCTCGTCATCTTGTCTACTCGTAAGAGGGAAATTTTGCTGATGCAGTGATGTCTGGAAATGGTATGGTTCGCTTTTGCCCCCTTAATGTATCTCCCGCCTGAGCTGAGCTGCAGCATTACAATTTCTCATGCAGTATAAGCCATTTACACCAAGGTGCCGCCGCACGAGCAGGAGCGGAGGGAGGACGTTGCGGCTTGATGTTTTTCTTTTCAGCCTTTTCAGTCTTTTAGCACAGGTTTCAACTGAATGTGAAGCAGCTTCGTAAGGCATCTTGTTTAagccatatttattttattgctatttGATCGTTTGCGAATGTCGTGAGTCGTtttgcgttatggatgtgacatttatgGACCGCAGTCGAACGGTCTGAAAGTGAGAAGATGTGAAGAAGCCTTTTTCATGCAGCAAAAAGGACTTGAGGGTGCATTGCTGACAGGAGACAGCCGGCAGAAGACGCATTCCTTCAGTAACGAGAGGCAGCCGAAGTGGATGCAGTGGAAAGGAACGATGGTCGAATCAGTGACAACTGCAGTGGGGCCACGCTGAAGAAAAGAACAAGTTATACTCTGTACCAGGATATATTTGAAGAACTGGAGAAAAGGAAGGAAAGCAACGCCTTTGGGAGGGCAATTGGATGTCTACTTCATTAAATTAACTCCTGCGGAGCTTCAACTTTGACCTGCAGGATGACAGTTGTGGCTGGGGACAACATGGATGAGACCTCTGCCGTGCCGGGGCATCCGCAGGACACATACCCCCCTGACCATGACGATCATGAATGCTGTGAACGGGTGGTCATCAATATAGCGGGCCTGCGATTCGAGACGCAGCTTAAAACTCTCGCCCAGTTCCCAGAGACTCTCTTAGGTAACCCAAAGAAGCGGATGCGTTATTTCGATCCCTTGAGAAACGAGTACTTCTTTGACAGAAATCGTCCGAGCTTTGATGCCATCCTGTACTATTATCAGTCCGGCGGACGACTGAGAAGGCCGGCGAATGTCCCGTTGGATATGTTCTCAGAAGAAATTAAGTTCTATGAACTTGGGGTGGAGGCAATGGAGAAGTTTCGTGAGGATGAGGGCTTTATCCGTGAGGAGGAGCGACCTTTACCAGAGAAAGAGTTTCAGCGACAAATCTGGCTCCTGTTTGAGCATCCTGAGAGCTCAGGGCCAGCCAGAGGAATTGCTATTGTGTCTGTTATGGTCATTTTAATTTCCATCGTCATTTTCTGTTTGGAGACTTTACCTGAACTGAAAGAGGACCCTGAGGGGCGTATAAAGATTATAGGCAACACCACATACTACTACAAACCTAGCATTCTGGCCGATCCATTCTTCATCATTGAGACCCTCTGCATTATCTGGTTTTCATTCGAATTGATAGTGCGCTTCTTTGCTTGCCCAAGCAAAGCGGCCTTCTTTAAGAACATGATGAACACCATTGACATTGTGGCTATTATCCCTTACTTCATCACGCTGGGCACAGAGTTAGCAGAGGAACAAGACGGAAAAGAGGGAAAGGGCGAGCAGGCAACATCACTGGCCATCCTCAGGGTGATCCGTCTGGTCAGGGTGTTCAGAATCTTCAAGCTGTCCAGGCACTCCAAAGGCCTTCAGATTTTAGGGCAGACCCTCAAAGCCAGTATGCGAGAGCTCGGATTGCTTATTTTCTTCCTCTTCATTGGCGTCATATTGTTCTCCAGTGCTGTGTATTTTGCAGAAGCAGAGGAAAAGGAGTCCTACTTCAGCAGCATCCCAGATGCATTCTGGTGGGCAGTTGTGTCAATGACTACCGTAGGCTACGGGGACATGGTCCCAGTGACCATCGGGGGCAAGATTGTGGGTTCCCTGTGCGCCATCGCTGGTGTGCTGACCATTGCCCTCCCCGTGCCAGTCATTGTGTCCAACTTCAACTATTTCTATCATAGAGAAACCGAAGGAGAGGAGCAGGCCCAACTCCTGAACGTGAGCAACCCGAACATTGCCTCCGATTCAAACTCTAGTCGCCGAAGCTCCTCAACCGTCAGCAAGTCTGAGTACATGGAGATAGATGGAGACATAAACAACAGCATCGACAATTTCAGAGAGGCCAACCTCAGAACTGGCAACTGCACTATCCCCAATCAGAACTGTGTGAACAAAAGTAAGCTGCTAACCGATGTCTAGAGGCACAGTTGAAAAGTCACGTGCTGACTGAAGTCACATATGAATGCTTACTTTACCTCCTCTCGTGAGCCCTTGCAATGCGAATAACTCTACAATGCAGACGAAAGAAAAATACTACACCAAAACATTTAGAACATAACTGCAACAAATGAGGCAGACAATTCAGTATATACATTTCCAAAGAGGATGAATGAGAAAAAAGCCTCCTCAAGCATCTAGCTAGCGTCCATGGGCATTGAAGGACTCTCGACGGCGGGATTACTAAAACATCACGCATGGACTACAGACTACATTTCAGCAAGCTGCACACTGCATCTGGGAAAGTGCATAAAAGACCAAGTGCAGTGTTCGGTGGACGCCTCATCCGTAGGTGGTCTTCCCCAACTGACCAGCAAAGCACCTTATATGAACAAGACTTATCTTCTGCTGGGATGCTACGGAGGCCAAGGTCATCGCCTCATGGACATCCGCATTGCTGCTATTTTCCAGCAGATGCTGTAATTTAGATATCACCAAGTGATTAAATGCCATGCCCTTTAGATATAAGACAGCACAATGCCGAAGGAGGAGCCTCATAGTTAGCATGTTTAGATTATCCTCATTTTGATATTGGCATGCGTCGGACATTACCTCATGAAGATAGGAAATCCATTCCTTTTTTGCTTTTGAAATTTTTGTGTTCAGCTCCATCAGCTCCCCTCTACATCGACCTCCTCTCATTGGTCGCCATGAAAAGTGCACTAGTGTGTCATGATTTGAGATGCTAATCATTTAGGTGTATTTAAAGACTGAATGTTTAACCTTATGGGAAACAGAATCTTAATGATATCATAGCATGTCAGAAGAACCTGCATTATGGCCTAATCAACTAAGGTACTGTGTATCCTAGTATATTTAATGCATGACATCGGTATAATACAGCTTGTTGCAATTGAGATACCTCATAAGGGTGTCATTGTTACAATCAGGGAAACTAGGGACATCGATTCCTTGATATTTTCTGAAATGTGACAAAATATATATGCAAGCCCCAACGCTGGGATGCAAACTTTTCAATCTAAAAAGTAGTCGAGGACACAGAAAAAGAACTATCAAGATACTATCAAATGCATATACTCATACTAAGCGCacctgttaaaaaaattatataacttAAATAGTGCAGTGCATGGGCATTCTCTCTCTtgggagagagagagcaa
>TCONS_00047739
ATGACAGTTGTGGCTGGGGACAACATGGATGAGACCTCTGCCGTGCCGGGGCATCCGCAGGACACATACCCCCCTGACCATGACGATCATGAATGCTGTGAACGGGTGGTCATCAATATAGCGGGCCTGCGATTCGAGACGCAGCTTAAAACTCTCGCCCAGTTCCCAGAGACTCTCTTAGGTAACCCAAAGAAGCGGATGCGTTATTTCGATCCCTTGAGAAACGAGTACTTCTTTGACAGAAATCGTCCGAGCTTTGATGCCATCCTGTACTATTATCAGTCCGGCGGACGACTGAGAAGGCCGGCGAATGTCCCGTTGGATATGTTCTCAGAAGAAATTAAGTTCTATGAACTTGGGGTGGAGGCAATGGAGAAGTTTCGTGAGGATGAGGGCTTTATCCGTGAGGAGGAGCGACCTTTACCAGAGAAAGAGTTTCAGCGACAAATCTGGCTCCTGTTTGAGCATCCTGAGAGCTCAGGGCCAGCCAGAGGAATTGCTATTGTGTCTGTTATGGTCATTTTAATTTCCATCGTCATTTTCTGTTTGGAGACTTTACCTGAACTGAAAGAGGACCCTGAGGGGCGTATAAAGATTATAGGCAACACCACATACTACTACAAACCTAGCATTCTGGCCGATCCATTCTTCATCATTGAGACCCTCTGCATTATCTGGTTTTCATTCGAATTGATAGTGCGCTTCTTTGCTTGCCCAAGCAAAGCGGCCTTCTTTAAGAACATGATGAACACCATTGACATTGTGGCTATTATCCCTTACTTCATCACGCTGGGCACAGAGTTAGCAGAGGAACAAGACGGAAAAGAGGGAAAGGGCGAGCAGGCAACATCACTGGCCATCCTCAGGGTGATCCGTCTGGTCAGGGTGTTCAGAATCTTCAAGCTGTCCAGGCACTCCAAAGGCCTTCAGATTTTAGGGCAGACCCTCAAAGCCAGTATGCGAGAGCTCGGATTGCTTATTTTCTTCCTCTTCATTGGCGTCATATTGTTCTCCAGTGCTGTGTATTTTGCAGAAGCAGAGGAAAAGGAGTCCTACTTCAGCAGCATCCCAGATGCATTCTGGTGGGCAGTTGTGTCAATGACTACCGTAGGCTACGGGGACATGGTCCCAGTGACCATCGGGGGCAAGATTGTGGGTTCCCTGTGCGCCATCGCTGGTGTGCTGACCATTGCCCTCCCCGTGCCAGTCATTGTGTCCAACTTCAACTATTTCTATCATAGAGAAACCGAAGGAGAGGAGCAGGCCCAACTCCTGAACGTGAGCAACCCGAACATTGCCTCCGATTCAAACTCTAGTCGCCGAAGCTCCTCAACCGTCAGCAAGTCTGAGTACATGGAGATAGATGGAGACATAAACAACAGCATCGACAATTTCAGAGAGGCCAACCTCAGAACTGGCAACTGCACTATCCCCAATCAGAACTGTGTGAACAAAAGTAAGCTGCTAACCGATGTCTAG

Function


symbol description
kcna1a Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within several processes, including potassium ion transport; protein homooligomerization; and regulation of ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in several cellular components, including dendrite; main axon; and neuronal cell body. Predicted to be integral component of membrane. Is expressed in several structures, including gill; heart; hindbrain; opercular flap; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in episodic ataxia type 1. Orthologous to human KCNA1 (potassium voltage-gated channel subfamily A member 1).

GO:

id name namespace
GO:0071805 potassium ion transmembrane transport biological_process
GO:0034765 regulation of ion transmembrane transport biological_process
GO:0051260 protein homooligomerization biological_process
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:0030425 dendrite cellular_component
GO:0043025 neuronal cell body cellular_component
GO:0045202 synapse cellular_component
GO:0044224 juxtaparanode region of axon cellular_component
GO:0033270 paranode region of axon cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0005216 ion channel activity molecular_function
GO:0005244 voltage-gated ion channel activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0005251 delayed rectifier potassium channel activity molecular_function
GO:0005267 potassium channel activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-110408-15 Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within several processes, including potassium ion transport; protein homooligomerization; and regulation of ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in several cellular components, including dendrite; main axon; and neuronal cell body. Predicted to be integral component of membrane. Is expressed in several structures, including gill; heart; hindbrain; opercular flap; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in episodic ataxia type 1. Orthologous to human KCNA1 (potassium voltage-gated channel subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000062942

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00047738 False 3380 mRNA 0.46 2 19954576 19958278
TCONS_00047739 True 1479 mRNA 0.49 1 19955598 19957076

Neighbor


gene id symbol gene type direction distance location
XLOC_024055 kcna6a coding upstream 3245 19947096 ~ 19951331 (+)
XLOC_024054 gramd4b coding upstream 17978 19870603 ~ 19936598 (+)
XLOC_024052 celsr1b coding upstream 85081 19753890 ~ 19869495 (+)
XLOC_024053 CU041386.1 coding upstream 179901 19774559 ~ 19774675 (+)
XLOC_024051 zgc:101783 coding upstream 202431 19733704 ~ 19752145 (+)
XLOC_024057 NA coding downstream 28790 19987068 ~ 19998226 (+)
XLOC_024058 zgc:194665 coding downstream 41345 19999623 ~ 20003528 (+)
XLOC_024059 tnni4b.1 coding downstream 118947 20077225 ~ 20087924 (+)
XLOC_024060 tnni4b.2 coding downstream 131708 20089986 ~ 20099773 (+)
XLOC_024061 NA coding downstream 144987 20103265 ~ 20109429 (+)
XLOC_023973 CR762411.1 misc upstream 4736467 15217824 ~ 15218109 (+)
XLOC_024041 NA non-coding upstream 509064 19443951 ~ 19445512 (+)
XLOC_024040 NA non-coding upstream 592489 19356344 ~ 19362087 (+)
XLOC_024031 NA non-coding upstream 1030185 18920543 ~ 18924391 (+)
XLOC_024029 CR391963.2 non-coding upstream 1069007 18884678 ~ 18885569 (+)
XLOC_024066 CR846093.3 non-coding downstream 634205 20592483 ~ 20592597 (+)
XLOC_024067 CR846093.2 non-coding downstream 645618 20603896 ~ 20604012 (+)
XLOC_024070 NA non-coding downstream 894922 20853200 ~ 20870875 (+)

Expression



Co-expression Network