XLOC_024073 (chrm2b)


Basic Information

Item Value
gene id XLOC_024073
gene name chrm2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 21046856 ~ 21061911 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00047761
CTGACAGCACAACAAAAACGTTGTATAAACAATTTTTACATTTGTGTCCTTctcttgaataataaaaaatttataaacattGGTTCCATCCATGTTAAATCTCCTCATTGTCCCCTGGCTTCTCATGTAGGTGTGTTTAGAGCCCACCCTCCGAGGCCCTCACGTTTACACACTGACAAGAGTTCATTTACAGTCAGTCACAGACAACAACAGACGCACAGCTCATCCTGAGCCTCACGACATAGATGACAGTCATCTGCATTTACAGGAGACATGACAGAATGATGAAGGACATCTGACTGAAAAAATAAGGTTCTGATGTATTGTGGTAAGGAAAGATGGAGACCTTCAACTTAACGCTTTCTCCAAGCTCCAGCCACGCTAACAAGACCAACATCTTCCAAGACGGTCCGTTCAAACCAGTGGAGTTTGTTCTCATTGTTCTCGGACTGAGCATCTTAAGCTTGATCACAATCATTGGCAACGTGCTGGTCATGCTCTCCATCAAGGTCAACAGGAACCTCCAGACGGTCAACAACTACTTTCTGTTCAGCCTTGCGTGCGCTGACCTGTTCATTGGCGTTTTCTCCATGAATCTCTACACTGTGTACATTGTGACCGGTCATTGGCCTTTAGGAGCTTTGGTGTGTGACCTCTGGTTGGCTCTGGACTATGTGGTGAGCAACGCCTCAGTTATGAACCTTCTCATCATCAGCTTTGACCGCTATTTCTGTGTCACCAAACCTCTCAGTTACCCAGTCAAACGGACCCACAAGATGGCAGGAATGATGATTGCCGCTGCTTGGATCCTGTCATTCATTCTCTGGGCTCCAGCTATTCTGTTCTGGCAGTTCATCACCGGCAGCAGGACAGTTCCTGAAGGCGAGTGCTATATCCAGTTTTTCTCCAACGCTGTGGTCACTTTTGGCACCGCCATTGCTGCTTTTTACCTGCCGGTGATCACCATGACCATCCTCTACTGGCAGATCTCCAAAGCAAGTCGCAGCCGTGTCAGACGCAGAGACAACCGGAGAGTTTCTAGAGTCAGTAATGATGGAGGTCAGGCTGGACTCGGGAATGAGAGAAATATGGATAGGAAGTCAACTCAGGAAGGAGAGGAAATGGTTTCACGTAAGCAGAGCGCTTCAGATACCACTACAGGAGAAGAGCGGGACAGTGAGAATGACTCTATATCCGGAAGTGTGCTTGCATCATCAAATCAGCGGGATGACGAGGCCGTGTCAATAAGCACCAACGGTGACATTAGAGCTCGCCAGAACCAATCAGCTTCACTGGCCACAGAAAGTTGGGTCAGATTCACATGCTTCAAAACGGCCTCCCAGAAAGACCTGCAAAACACATATAAGGTCAACAGCGAAAGTCAGGGCATGACAAATGGGAAGGAAAGATTGAGTCTGGTGTCGCAGAAGATTATCAGTCCACATTCTCAAAAGAGAAAGAGTTCCTCCTCCAGAGAAAAGAAAGTGACAAGAACCATTATGGCCATTTTGGTGGCATTCGCAACCACGTGGACCCCTTACAATGTGATGGTGCTCATCAACACTTTCTGCTCGGACTGTATTCCGAACACAGTGTGGATCTTTGGCTACTGGCTCTGCTATATAAACAGCACGGTTAACCCGGCCTGCTATGCGCTGTGCAATGTCACCTTTAAGAACACCTTCAAACAGCTGCTGACGTGCAAGTACAGGAATATTCACGCCACCAGAAAACAGTAGAGTTGGCAAAAGAGTTGCTAACTAAAAATAGTTGAGAATATGCAGAGTCTGGAGGCTTCAAGTTCAAACTGTTGAAACATTCAAGTGATGCTTCAACAGCACAAATATGAGGACGAGGCTTACTCATGAAGCAGCGGAGATggtttatttctttgtatttaaaaaaaaatatggccACACTTTTACACTAAGGTTCCATTACTTAATATTAGTTTAAGAGACACTCTGCTTTTTAAGAAATAAGCTGATTTTACAAGTCACCCAGAGGAAAACAGTTGAGTTTAACCATTTTTGAAttaattcagctgatctctgggtctggtggaAGTACTTTTAGCCAGTGTTAGGCAAGCTCCTTGAAAAATGTTgagagctaagctattagctactcaaTACGTaacttaactacactaaaagatACCCTcttggaaatgtagcaagctaagctaaaagctgcTTGGCAAAAATAgattagctacatctaagctacttttgcaattttcatttttaaatcaaatcaacttaaatccaagtcgaTCATAACTTAGTGACCAATAAAACTGTCCATAAAACATAGAGgctcagtttagttccaaccctgctccaacacacttagcCTACCTGTatggtttcaaacaaacctgaaagactcaattagtttgatcaggtgtggttaattagggttggaactaaacggtgcagggctgcggccctccaggaattgactttgacatCCCTGTTCTATATCTAGTAAGAGCCTGATTAGcgggttcaggtgtttttgattagggttggaactgaactctccaggacaccggccccccagggccaatttggacacccctgttttagattcatataattattaatcacctgtttctaaatagTCTGTCTCTAAAAGTTAGGGGGACGTATCCCCTGTCCTCCCTGGTGATTTAtggtaaagggaaatatttagtaaaaagcattattcatttatttaatttctttttggcttactccctttattaatctggggtcaccacagcggaatgaaccgacttATCCAGCTTATCCAGCCccttttttcgcagcggatgcccttccagccacaacccatctctgggaaacatccacacacacatatatactataTAATGTTTCTTTTTGGGTGactcactacctactgcgccactgcgtcacccaaaaagaaacattatattgtatatatatttacgacTCTTCATTATTGAATTACGCTACATAATgtagtattattaataactatcatgaactaatagtaattaccatagtatactttagtctttactacagtaaactatataaatattatatatatatatatatttatctatatctTCTCTCCCTCAGTCTCCCTCTGTTATCTTTATATCTGtccatcaagcaaatttctcCGTCGTTTTCTCTGTTGTTACAAACATAatttgttgatttgccatttcccaaatctGTCGCTCCGACGAACATTCATAAACTGCATCGCAAGCTTGAGCACTCGCTGTAGTTTGAAACATTCTGGCTGTTCTATTGCCACTTATGCCCCTATGCCCTATTTAAAACATTCTTACTTTCAatgttggaattattaaaaattatatatatacatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatagccgggctactatccgcttgttaagtggtgacgtgtttgtgacgtaagTAATACTGTTTcgcaacaatctctgggcttgctgcataccaaaatatcaaaaattttacaatttataaaaaataatcactttctggccatcggatattaggctaggatattgcgatcgtgattttcgaaagccttaaatcgctgtgtaaatgtttattattaccatttcatgagtctccccattcagttgaatagagcgcttggacccggaagccgcttcgcatgatgtcacacttaacaagcggatagccaATGACAAACATCAATTCAATGCTGATAGCAgcaaaaatcttgggctgtggacaatgtgaaacaaaaattgttctctgatgagtcccaTATAATGGTGaagagttatggtgtggagaagccccaaagaagtgaAGCATGCCCAGAGTAGAGCATGGgtgtggatcagtgatggtttgggctgcaatatcatggtaTTCCCTAAGCataatacttgtgctagatgggctCATCACTGTTGAGGATGACCAAACGATTCAAGAGGACAATGTGCACCCattggttcaaacattgtatcctgaaggcggtgctgtgtatcaggatgataatgcaccaatatacACAGCaggactggtgacagagtggtttgatgaacatgaaagtgaattTAAACATGACCTGAACAGTCACCAAATCCAAATATTATTGAGcaactttggggtgttttggaggagcgcgTCAAAAATGTTTTCCTCTAACAGCATCCTCTAACAGCATCACCAGGCCACTGGCTACTATTTTGCAGGAAGATAGtatcaaaatccctctggccaaagtgcaggacttgtatctgtcatttccAAGATGAAGTGATGCTGTTTTGGCTGCAAAAGGAGGCCCTGCACCATACTATTGAATTATTGTGGGATAAAACCAGGCGTTTCAGTTTCATCGTCCAAcccctatatatacatatatatatagtgtactaAAGCCATAACCATGGAAACTGTGTGACCATctcaatcattttgactttactaaaactaaataaataaataatttttactttttattaatcaACAATAATCTATATACCTAAAATAGTTTCAGTCTTGTTGAACAAGGATTGTTTTAGGTCATAAATTTTAAGGATCACAAATAACTCTTTTAAGATTTACTTGATAAAATCTTCATAATAATTTGCACAAGTGAAATTTAAGTCAATTTTACTATCGTACATCAAGTCAATATTACATTAAATGCACTTAATATTAAACTCGACActcctaaataaagtgaaagttAATTGATTGTCTTTAATTTGAcgtctatatttatttaaatgaaaagtaaTGTCATTTTTTTGCGAATAAAACACTGAATCTTATTGAATGCAAGTTAGTTCACTTGGCGTGACGTAATTTAATTTAGACACACAtctccaaaaatgtttttattaaaaatgtaaatagaacAAAAGAGCAATTTTACTTTGAAATGCCTACTGATCGTACAGTTAGTATCAGCACAGTTATGGCTCTCTGAGTGAAGTCTCAATAGTAATGctgttaataaaaatgcaaaaagacaaagcaTAAGTGCTACGTTTCTGCGTAATCCACTGCATAATGTCTCCTTCactatattggggcattaggactcacaaagactgcaggttgagcgtcccctgctggcctcactaacaccttcAGCTACCTAGTTTTCCCATCAACCCtatagcttcagtgagtaaccggtcttgggttgcagggtgatatggctgtggccactgaaatctgatccggcacctcatttacCGATCCCCCTCATCAACTGCCTAACCCCCTGTTCAttttcactttcttccacgactCCCCAAGCCTCTTCACTCTTCTGGCTATTCTGCAAGAGGACTGGCTGAAAAACCCTTCATTTATTctcaacacaaaacaattaagttaaagtGGACTAAACAGAAGAAAATAAGTGTCTATTGTACAGTTTTGCACAAGCAGCAATGTAgatgacattttttttctgtaaagttttcacttattttgttatattttaacaaaattttgtttatattttcaattttataacaGATGGATATGTTTTTGTAAGTTTCCTTGTCCTGTTCCTGTCCAAATCAATACTTTTCTAATAaaatttctgaaatatttatttgcaacgattaaaaaatattacaagtaaatgaatattaaaacttTAACccactcatttcatttattacatcaaatgaatgtgtaaatattaaatattttacttaggAAATTCTAGttatttttgccatttattatattatatccaaaatataaatgaattgtcCATTGAAATCTTTATACTATTTTAGTATCCTTTGAACCTGCAGGTTTTACCCACTTTCAGCAAGAAGTATGATCcctgtatatttgtatatactgTTAATACATATTAGaacaagtttgttgtttcactGAATAATCATGGACATTATATCACAAATGTTATTTGAATCATTCGACACTTTctatgaatataaaatatgtcctgtgtgtgtttgtgtgtgtgtgtatataatgcaTCACTTGTGAACAGCTCAACTTTTGTATGATAATtaaactgccagcacattttctgttgttttacagactcTGCATATTAGTTATTATACATTACatcatttcaaactactaaaatgtcaataaaagtcattttttaactgtagagttgaattttcgaCATCACAatttgacagagcagagatcacagtctcataatgcaatttacaaccgtATAAAT
>TCONS_00047762
ATGGAGACCTTCAACTTAACGCTTTCTCCAAGCTCCAGCCACGCTAACAAGACCAACATCTTCCAAGACGGTCCGTTCAAACCAGTGGAGTTTGTTCTCATTGTTCTCGGACTGAGCATCTTAAGCTTGATCACAATCATTGGCAACGTGCTGGTCATGCTCTCCATCAAGGTCAACAGGAACCTCCAGACGGTCAACAACTACTTTCTGTTCAGCCTTGCGTGCGCTGACCTGTTCATTGGCGTTTTCTCCATGAATCTCTACACTGTGTACATTGTGACCGGTCATTGGCCTTTAGGAGCTTTGGTGTGTGACCTCTGGTTGGCTCTGGACTATGTGGTGAGCAACGCCTCAGTTATGAACCTTCTCATCATCAGCTTTGACCGCTATTTCTGTGTCACCAAACCTCTCAGTTACCCAGTCAAACGGACCCACAAGATGGCAGGAATGATGATTGCCGCTGCTTGGATCCTGTCATTCATTCTCTGGGCTCCAGCTATTCTGTTCTGGCAGTTCATCACCGGCAGCAGGACAGTTCCTGAAGGCGAGTGCTATATCCAGTTTTTCTCCAACGCTGTGGTCACTTTTGGCACCGCCATTGCTGCTTTTTACCTGCCGGTGATCACCATGACCATCCTCTACTGGCAGATCTCCAAAGCAAGTCGCAGCCGTGTCAGACGCAGAGACAACCGGAGAGTTTCTAGAGTCAGTAATGATGGAGGTCAGGCTGGACTCGGGAATGAGAGAAATATGGATAGGAAGTCAACTCAGGAAGGAGAGGAAATGGTTTCACGTAAGCAGAGCGCTTCAGATACCACTACAGGAGAAGAGCGGGACAGTGAGAATGACTCTATATCCGGAAGTGTGCTTGCATCATCAAATCAGCGGGATGACGAGGCCGTGTCAATAAGCACCAACGGTGACATTAGAGCTCGCCAGAACCAATCAGCTTCACTGGCCACAGAAAGTTGGGTCAGATTCACATGCTTCAAAACGGCCTCCCAGAAAGACCTGCAAAACACATATAAGGTCAACAGCGAAAGTCAGGGCATGACAAATGGGAAGGAAAGATTGAGTCTGGTGTCGCAGAAGATTATCAGTCCACATTCTCAAAAGAGAAAGAGTTCCTCCTCCAGAGAAAAGAAAGTGACAAGAACCATTATGGCCATTTTGGTGGCATTCGCAACCACGTGGACCCCTTACAATGTGATGGTGCTCATCAACACTTTCTGCTCGGACTGTATTCCGAACACAGTGTGGATCTTTGGCTACTGGCTCTGCTATATAAACAGCACGGTTAACCCGGCCTGCTATGCGCTGTGCAATGTCACCTTTAAGAACACCTTCAAACAGCTGCTGACGTGCAAGTACAGGAATATTCACGCCACCAGAAAACAGTAG

Function

symbol description
chrm2b Predicted to enable G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; chemical synaptic transmission; and regulation of smooth muscle contraction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in postsynaptic membrane. Predicted to be integral component of membrane. Predicted to be active in dendrite and synapse. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; bipolar disorder; heroin dependence; major depressive disorder; and schizophrenia. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger biological_process
GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway biological_process
GO:0006940 regulation of smooth muscle contraction biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0007165 signal transduction biological_process
GO:0030425 dendrite cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0045211 postsynaptic membrane cellular_component
GO:0030054 cell junction cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function
GO:0030594 neurotransmitter receptor activity molecular_function
GO:0016907 G protein-coupled acetylcholine receptor activity molecular_function
GO:0004993 G protein-coupled serotonin receptor activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090410-3 Predicted to enable G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; chemical synaptic transmission; and regulation of smooth muscle contraction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in postsynaptic membrane. Predicted to be integral component of membrane. Predicted to be active in dendrite and synapse. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; bipolar disorder; heroin dependence; major depressive disorder; and schizophrenia. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2).

Ensembl:

ensembl_id ENSDARG00000116374

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00047761 False 6272 mRNA 0.38 3 21046856 21061911
TCONS_00047762 True 1401 mRNA 0.49 2 21054065 21057378

Neighbor

gene id symbol gene type direction distance location
XLOC_024072 NA coding upstream 48241 20997679 ~ 20998615 (+)
XLOC_024071 NA coding upstream 87274 20959183 ~ 20959582 (+)
XLOC_024070 NA coding upstream 175981 20853200 ~ 20870875 (+)
XLOC_024069 ergic2 coding upstream 319869 20715950 ~ 20726987 (+)
XLOC_024068 kxd1 coding upstream 344932 20694177 ~ 20701924 (+)
XLOC_024074 NA coding downstream 30332 21092243 ~ 21092575 (+)
XLOC_024075 rad52 coding downstream 36764 21098675 ~ 21115213 (+)
XLOC_024076 erc1a coding downstream 115026 21176937 ~ 21253162 (+)
XLOC_024077 CR384055.1 coding downstream 197318 21259229 ~ 21296202 (+)
XLOC_024078 fgl2b coding downstream 205668 21267579 ~ 21273875 (+)
XLOC_023973 CR762411.1 misc upstream 5828747 15217824 ~ 15218109 (+)
XLOC_024067 CR846093.2 non-coding upstream 442844 20603896 ~ 20604012 (+)
XLOC_024066 CR846093.3 non-coding upstream 454259 20592483 ~ 20592597 (+)
XLOC_024079 NA non-coding downstream 262677 21324588 ~ 21344673 (+)
XLOC_024080 NA non-coding downstream 436376 21498287 ~ 21499896 (+)
XLOC_024092 CR759863.2 non-coding downstream 1427778 22489689 ~ 22491864 (+)
XLOC_024093 NA non-coding downstream 1430082 22491993 ~ 22497122 (+)

Expression


Co-expression Network