XLOC_024091 (cyp11a1)


Basic Information

Item Value
gene id XLOC_024091
gene name cyp11a1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 22319940 ~ 22335283 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00047790
TTGGTTCTTTCCTTGAGTGACTGATATCACGTCTCCACAGGCGGCAAACaagtagagagagagagtgtgatggCCCGCTGGAATGTGACGTTCGCTCGTCTGGATCAGTCCCTGTCTTCATTGAAAAATCTGCTGCAGGTCAAGGTGACTCGCTCAGGCAGAGCACCGCAAAACTCCACTGTCCAGCCATTCAATAAGATCCCTGGACGATGGAGGAACAGCCTGCTCAGTGTCCTTGCCTTCACCAAAATGGGAGGCCTCAGGAATGTCCACCGAATTATGGTGCACAATTTCAAAACATTTGGTCCAATTTACAGGGAAAAAGTTGGAATCTACGATAGTGTGTACATCATAAAGCCTGAAGACGGTGCTATCCTGTTCAAAGCTGAGGGCCATCACCCCAATAGAATCAATGTAGACGCGTGGACCGCCTACAGGGACTACAGGAACCAAAAATATGGCGTCCTGCTAAAAGAAGGGAAGGCCTGGAAGACTGATAGGATGATTCTAAACAAGGAACTGCTTTTGCCGAAGTTGCAGGGGACCTTTGTGCCTCTCCTGGAGGAGGTCGGGCAGGACTTTGTGGCTCGTGTCAACAAACAGATTGAGAGGAGTGGGCAAAAACAGTGGACCACAGATCTGACCCATGACCTCTTCAAGTTTTCACTGGAATCGGTGAGTGCTGTGTTGTATGGGGAGCGTTTGGGTCTTCTGTTGGACAACATTGATCCAGAATTTCAGCACTTCATTGACTGCGTCTCAGTCATGTTTAAGAC
>TCONS_00047791
GGTTCTTTCCTTGAGTGACTGATATCACGTCTCCACAGGCGGCAAACgtttcgtcctccatacAAACCCTGCATAAATGAGtagagagagagagtgtgatggCCCGCTGGAATGTGACGTTCGCTCGTCTGGATCAGTCCCTGTCTTCATTGAAAAATCTGCTGCAGGTCAAGGTGACTCGCTCAGGCAGAGCACCGCAAAACTCCACTGTCCAGCCATTCAATAAGATCCCTGGACGATGGAGGAACAGCCTGCTCAGTGTCCTTGCCTTCACCAAAATGGGAGGCCTCAGGAATGTCCACCGAATTATGGTGCACAATTTCAAAACATTTGGTCCAATTTACAGGGAAAAAGTTGGAATCTACGATAGTGTGTACATCATAAAGCCTGAAGACGGTGCTATCCTGTTCAAAGCTGAGGGCCATCACCCCAATAGAATCAATGTAGACGCGTGGACCGCCTACAGGGACTACAGGAACCAAAAATATGGCGTCCTGCTAAAAGAAGGGAAGGCCTGGAAGACTGATAGGATGATTCTAAACAAGGAACTGCTTTTGCCGAAGTTGCAGGGGACCTTTGTGCCTCTCCTGGAGGAGGTCGGGCAGGACTTTGTGGCTCGTGTCAACAAACAGATTGAGAGGAGTGGGCAAAAACAGTGGACCACAGATCTGACCCATGACCTCTTCAAGTTTTCACTGGAATCGGTGAGTGCTGTGTTGTATGGGGAGCGTTTGGGTCTTCTGTTGGACAACATTGATCCAGAATTTCAGCACTTCATTGACTGCGTCTCAGTCATGTTTAAGACCACCTCACCCATGCTGTACCTACCCCCG
>TCONS_00047792
GGTTCTTTCCTTGAGTGACTGATATCACGTCTCCACAGGCGGCAAACgtttcgtcctccatacAAACCCTGCATAAATGAGCGTCAGaagtagagagagagagtgtgatggCCCGCTGGAATGTGACGTTCGCTCGTCTGGATCAGTCCCTGTCTTCATTGAAAAATCTGCTGCAGGTCAAGGTGACTCGCTCAGGCAGAGCACCGCAAAACTCCACTGTCCAGCCATTCAATAAGATCCCTGGACGATGGAGGAACAGCCTGCTCAGTGTCCTTGCCTTCACCAAAATGGGAGGCCTCAGGAATGTCCACCGAATTATGGTGCACAATTTCAAAACATTTGGTCCAATTTACAGGGAAAAAGTTGGAATCTACGATAGTGTGTACATCATAAAGCCTGAAGACGGTGCTATCCTGTTCAAAGCTGAGGGCCATCACCCCAATAGAATCAATGTAGACGCGTGGACCGCCTACAGGGACTACAGGAACCAAAAATATGGCGTCCTGCTAAAAGAAGGGAAGGCCTGGAAGACTGATAGGATGATTCTAAACAAGGAACTGCTTTTGCCGAAGTTGCAGGGGACCTTTGTGCCTCTCCTGGAGGAGGTCGGGCAGGACTTTGTGGCTCGTGTCAACAAACAGATTGAGAGGAGTGGGCAAAAACAGTGGACCACAGATCTGACCCATGACCTCTTCAAGTTTTCACTGGAATCGGTGAGTGCTGTGTTGTATGGGGAGCGTTTGGGTCTTCTGTTGGACAACATTGATCCAGAATTTCAGCACTTCATTGACTGCGTCTCAGTCATGTTTAAGACCACCTCACCCATGCTGTACCTACCCCCGGGCCTGCTTCGGTCCATAGGGTCCAACATTTGGAAAAACCACGTTGAAGCCTGGGATGGCATCTTTAACCAGGCTGACCGATATATCCAGAATATCTTCAAACAATGGAAAGAAAATCCAGAAGGCAATGGGAAGTATCCTGGTGTACTGGCAATCCTTCTAATGCAGGACAAACTGTCCATCGAGGATATAAAGGCCAGTGTCACCGAGCTGATGGCTGGAGGGGTGGACTCGgttaCTTTCACACTGCTGTGGACGCTTTATGAACTGGCTCGACAGCCAGACCTACAGGACGAGCTCCGAGCAGAAATCTCAGCCGCTCGTATTGCCTTTAAAGGAGACATGGTACAGATGGTCAAGATGATTCCTTTGCTTAAAGCAGCCCTGAAAGAAACTCTCAGATTACATCCTGTAGCAATGAGTCTTCCAAGGTTCATCACTGAAGATACGGTCATACAAAATTACCACATTCCAGCAGGGACTTTAGTTCAGCTGGGTGTCTATGCTATGGGTCGTGATCATCAGTTCTTCCCGAAACCAGAGCAATACTGTCCCTCTCGCTGGATCAGTTCTAAGAGACAGTACTTCAAGAGCCTGGGCTTCGGCTTTGGTCCCCGCCAGTGTCTGGGTCGCAGGATTGCCGAGACTGAAATGCAGATCTTCCTAATTCATATGCTGGAGAATTTCAGGATTGAGAAGCAGAAGCAGATTGAGGTCAGGAGCAAGTTTGAGCTCCTTTTAATGCCAGAGAAGCCCATCATGCTTACCATCAAACCACTGAATGCCAGCAGATAGCAGAGATGCAAACAGGAAATGACGTCAAGTATGGAAGCTTTGAGGGTGGCAAATATCCACTTTTGAGTTTTAGAGATTTGAATGTACAGTATGTTTCTTATCATTTAAAGAGATACTTTagtgtttactcaccctcacatAATACCAAAACCGTTCAACTTTCTGTTGAATCTATTCAAACAACATCTGAAATTAATTTATCTGTTTTAAAATATCTATTGGTGTCATCCACAGAAAAAAAGGcgagtaaataatgaaaaatatagtCTAAGAGTTTAAAGCAACACTTTGTCTTAAGGTGTCCTTATTTATTTAATCCATATGTATATCCCTGTTAATATGCCTGGATCTGTTATTGTGTGTGAGTTGGGCACTATAATATGAGACCATGAtccttttaaatgtaaatttgatATTCTATTATGCTGGGATATATTGTGTTATGAATAACATTTCAGTGATTTgcaatttcaattattttattctttgttgttctAATAAATCTTGCATATTTTTATCTGTGAATCAATAAATTGAAATCTCATCTA
>TCONS_00047793
GACTGATATCACGTCTCCACAGGCGGCAAACgtttcgtcctccatacAAACCCTGCATAAATGAGaagtagagagagagagtgtgatggCCCGCTGGAATGTGACGTTCGCTCGTCTGGATCAGTCCCTGTCTTCATTGAAAAATCTGCTGCAGGTCAAGGTGACTCGCTCAGGCAGAGCACCGCAAAACTCCACTGTCCAGCCATTCAATAAGATCCCTGGACGATGGAGGAACAGCCTGCTCAGTGTCCTTGCCTTCACCAAAATGGGAGGCCTCAGGAATGTCCACCGAATTATGGTGCACAATTTCAAAACATTTGGTCCAATTTACAGGGAAAAAGTTGGAATCTACGATAGTGTGTACATCATAAAGCCTGAAGACGGTGCTATCCTGTTCAAAGCTGAGGGCCATCACCCCAATAGAATCAATGTAGACGCGTGGACCGCCTACAGGGACTACAGGAACCAAAAATATGGCGTCCTGCTAAAAGAAGGGAAGGCCTGGAAGACTGATAGGATGATTCTAAACAAGGAACTGCTTTTGCCGAAGTTGCAGGGGACCTTTGTGCCTCTCCTGGAGGAGGTCGGGCAGGACTTTGTGGCTCGTGTCAACAAACAGATTGAGAGGAGTGGGCAAAAACAGTGGACCACAGATCTGACCCATGACCTCTTCAAGTTTTCACTGGAATCGGTGAGTGCTGTGTTGTATGGGGAGCGTTTGGGTCTTCTGTTGGACAACATTGATCCAGAATTTCAGCACTTCATTGACTGCGTCTCAGTCATGTTTAAGACCACCTCACCCATGCTGTACCTACCCCCGGGCCTGCTTCGGTCCATAGGGTCCAACATTTGGAAAAACCACGTTGAAGCCTGGGATGGCATCT
>TCONS_00047794
ttattaatttatttgattattaatttattgttttatttatgcagggatttaatttatttaagtaatttatgtatttgctttatttatgcaggaatttgtgagggtttaagtttatttatttgtttgtttatttattctttagttttatctttaaatgcatttactcattaattaattaatttatttattgttttatttatgtaggaGTTTAcgtatttactcatttatttgcacatttatttgttttatttattcactgtTTTGTTTATAAGGGGAATTTATGGTTTTATCgagtcatttattgatttatttacatatttattttttgcatttatgcaggaatttatggatttactAAGCAATTTATTTGCTTTATGCAGGATTTGTGGATGTACtttaatcattaattaaattttacatttttttatttatttgcatatttattgtatttgcaggtttcgtcctccatacAAACCCTGCATAAATGAGGTAATCGTGAAACTTTTATATAGTCTAACATACAACACAATTGTCATTTTACATATTTGTGAAtcattttttaatgcaatattttatatattttttaaactgtgcatGAGGATCCAATAAGCTTTGTTTTCTAATCATAATTTTAGATGACCCGCAACAAATAGCCAAGTGTAAAAATAGCACTATAAAGCGTCAGaagtagagagagagagtgtgatggCCCGCTGGAATGTGACGTTCGCTCGTCTGGATCAGTCCCTGTCTTCATTGAAAAATCTGCTGCAGGTCAAGGTGACTCGCTCAGGCAGAGCACCGCAAAACTCCACTGTCCAGCCATTCAATAAGATCCCTGGACGATGGAGGAACAGCCTGCTCAGTGTCCTTGCCTTCACCAAAATGGGAGGCCTCAGGAATGTCCACCGAATTATGGTGCACAATTTCAAAACATTTGGTCCAATTTACAGGGAAAAAGTTGGAATCTACGATAGTGTGTACATCATAAAGCCTGAAGACGGTGCTATCCTGTTCAAAGCTGAGGGCCATCACCCCAATAGAATCAATGTAGACGCGTGGACCGCCTACAGGGACTACAGGAACCAAAAATATGGCGTCCTGCTAAAAGAAGGGAAGGCCTGGAAGACTGATAGGATGATTCTAAACAAGGAACTGCTTTTGCCGAAGTTGCAGGGGACCTTTGTGCCTCTCCTGGAGGAGGTCGGGCAGGACTTTGTGGCTCGTGTCAACAAACAGATTGAGAGGAGTGGGCAAAAACAGTGGACCACAGATCTGACCCATGACCTCTTCAAGTTTTCACTGGAATCGGTGAGTGCTGTGTTGTATGGGGAGCGTTTGGGTCTTCTGTTGGACAACATTGATCCAGAATTTCAGCACTTCATTGACTGCGTCTCAGTCATGTTTAAGACCACCTCACCCATGCTGTACCTACCCCCGGGCCTGCTTCGGTCCATAGGGTCCAACATTTGGAAAAACCACGTTGAAGCCTGGGATGGCATCTTTAACCAGGCTGACCGATATATCCAGAATATCTTCAAACAATGGAAAGAAAATCCAGAAGGCAATGGGAAGTATCCTGGTGTACTGGCAATCCTTCTAATGCAGGACAAACTGTCCATCGAGGATATAAAGGCCAGTGTCACCGAGCTGATGGCTGGAGGGGTGGACTCGgttaCTTTCACACTGCTGTGGACGCTTTATGAACTGGCTCGACAGCCAGACCTACAGGACGAGCTCCGAGCAGAAATCTCAGCCGCTCGTATTGCCTTTAAAGGAGACATGGTACAGATGGTCAAGATGATTCCTTTGCTTAAAGCAGCCCTGAAAGAAACTCTCAGATTACATCCTGTAGCAATGAGTCTTCCAAGGTTCATCACTGAAGATACGGTCATACAAAATTACCACATTCCAGCAGGGACTTTAGTTCAGCTGGGTGTCTATGCTATGGGTCGTGATCATCAGTTCTTCCCGAAACCAGAGCAATACTGTCCCTCTCGCTGGATCAGTTCTAAGAGACAGTACTTCAAGAGCCTGGGCTTCGGCTTTGGTCCCCGCCAGTGTCTGGGTCGCAGGATTGCCGAGACTGAAATGCAGATCTTCCTAATTCATATGCTGGAGAATTTCAGGATTGAGAAGCAGAAGCAGATTGAGGTCAGGAGCAAGTTTGAGCTCCTTTTAATGCCAGAGAAGCCCATCATGCTTACCATCAAACCACTGAATGCCAGCAGATAG

Function

symbol description
cyp11a1 Predicted to enable cholesterol monooxygenase (side-chain-cleaving) activity. Acts upstream of or within several processes, including C21-steroid hormone biosynthetic process; epiboly; and positive regulation of microtubule polymerization. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in brain; endocrine system; female organism; interrenal primordium; and yolk syncytial layer. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia and congenital adrenal insufficiency. Orthologous to human CYP11A1 (cytochrome P450 family 11 subfamily A member 1).

GO:

id name namespace
GO:0006629 lipid metabolic process biological_process
GO:0008202 steroid metabolic process biological_process
GO:0008203 cholesterol metabolic process biological_process
GO:0048545 response to steroid hormone biological_process
GO:0006694 steroid biosynthetic process biological_process
GO:0006700 C21-steroid hormone biosynthetic process biological_process
GO:0071375 cellular response to peptide hormone stimulus biological_process
GO:0006704 glucocorticoid biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0031116 positive regulation of microtubule polymerization biological_process
GO:0034650 cortisol metabolic process biological_process
GO:0090504 epiboly biological_process
GO:0061371 determination of heart left/right asymmetry biological_process
GO:0005743 mitochondrial inner membrane cellular_component
GO:0016020 membrane cellular_component
GO:0005739 mitochondrion cellular_component
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen molecular_function
GO:0004497 monooxygenase activity molecular_function
GO:0005506 iron ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0020037 heme binding molecular_function
GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-010306-1 Predicted to enable cholesterol monooxygenase (side-chain-cleaving) activity. Acts upstream of or within several processes, including C21-steroid hormone biosynthetic process; epiboly; and positive regulation of microtubule polymerization. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in brain; endocrine system; female organism; interrenal primordium; and yolk syncytial layer. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia and congenital adrenal insufficiency. Orthologous to human CYP11A1 (cytochrome P450 family 11 subfamily A member 1).

Ensembl:

ensembl_id ENSDARG00000002347

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00047790 False 776 mRNA 0.49 5 22319940 22326497
TCONS_00047791 False 833 mRNA 0.49 6 22319942 22326525
TCONS_00047792 False 2185 mRNA 0.44 11 22319942 22335283
TCONS_00047793 False 884 mRNA 0.50 6 22319958 22326589
TCONS_00047794 True 2235 mRNA 0.41 10 22320738 22334735

Neighbor

gene id symbol gene type direction distance location
XLOC_024090 cyp11a2 coding upstream 8398 22296666 ~ 22311542 (+)
XLOC_024089 stoml1 coding upstream 27039 22281441 ~ 22292901 (+)
XLOC_024088 nr2e3 coding upstream 41285 22274642 ~ 22278655 (+)
XLOC_024087 hexa coding upstream 78628 22216723 ~ 22241312 (+)
XLOC_024086 sigirr coding upstream 173631 22107643 ~ 22146309 (+)
XLOC_024092 CR759863.2 coding downstream 154406 22489689 ~ 22491864 (+)
XLOC_024093 NA coding downstream 156710 22491993 ~ 22497122 (+)
XLOC_024094 stra6 coding downstream 236192 22571475 ~ 22634675 (+)
XLOC_024095 ush1c coding downstream 308671 22643954 ~ 22704233 (+)
XLOC_024096 abcc8 coding downstream 384569 22719852 ~ 22849186 (+)
XLOC_023973 CR762411.1 misc upstream 7101831 15217824 ~ 15218109 (+)
XLOC_024080 NA non-coding upstream 820044 21498287 ~ 21499896 (+)
XLOC_024079 NA non-coding upstream 975267 21324588 ~ 21344673 (+)
XLOC_024074 NA non-coding upstream 1227365 21092243 ~ 21092575 (+)
XLOC_024072 NA non-coding upstream 1321325 20997679 ~ 20998615 (+)
XLOC_024071 NA non-coding upstream 1360358 20959183 ~ 20959582 (+)
XLOC_024098 NA non-coding downstream 641306 22976589 ~ 22980625 (+)
XLOC_024099 CR396595.3 non-coding downstream 729344 23064627 ~ 23112585 (+)
XLOC_024100 CR396595.4 non-coding downstream 793415 23128698 ~ 23131139 (+)

Expression


Co-expression Network