XLOC_024374 (spg11)


Basic Information

Item Value
gene id XLOC_024374
gene name spg11
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 1088693 ~ 1126311 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00048196
agagtgctGCAGGTGAGCCGCTGTGACCCTCAGAGTCGCCGTCTGCTGGAGAAGCTCCTCCAGGACTCAGACTCGTCCTCCACGTCTCTGCTGGATCCGCTGCGTCTGCACTGGGTCAATCACTGGGACAGAGACGCGCAGACGCACATCCTGCTgtcccgcacacacacacacaCTCAGTGTTCAGGGGACGCGGCGGTGCTGTGGGCGTATCTGACATCTCTGCATGACTCGGTCCGCTGCTCTGCATGGCTGTCATCATCATCTGTGTGTGAGCGAGAGAGCAGCgctgccccctgctggccacagCTCACAGCACACGTCCTGGACACCTGCACCCGCTGTGGAGAACACCTGCGCAACATCATCCTGGACCAGCTCGCACGACAGGGGCAGTTTGTGCCGGCCGAGATGCAGGACTTCCAGCAGCTGCTGTGGAGACTGGCTCAGGCTGGAGGAGTGATGCATGATGGGAAGGAGCCTTCGCTTCCTCAGGCTGGAGGAGTGATGCATGATGGGAAGGAGCTCTGCTGTTCACAGGAGCAGGAGTTTCACCAGCGCTTCATCCTGCACTGTCTGGAGAACAACCTGCAGTTCCTGCTCTACACCTACCTGGAGCACTACGGGCTGAGCCCAGAGAACTGTCCTCTCCTGAGCgacagcagtgtgtgtgagagtttccCCTGCTTCCAGATGATGCTGAAGCTGCAGAAGATCACCACACACCTCACAGagCCGGAGTGTGTGTTTGAGGCGAGTCTGGCAGCTGCGCAGGTTCTTCTTCTCCCCGGCAGTCAGGCGAGCATCAGCAGTGTGTTACTGGAGGGACACAGCCTGCTCACACTCGCCACAGCCATGTTCACAGCCGGCGGCatacagcaggcggtCAGTACAGTGGACCCTCAGCTCCTCAGGATGGCTCTCCGTCAGTATCCTCAACTGAAGACAGCGCTGTTCCCTCAGAGCGGCCCTCGCGGAGATGTCTCGCTCTACCACCTGCTGCAGTCTCTACATCCCCTGGACTCCTCCAGACTCTTCGGATGGCAGTCCGCCAACAGTGTGTCTGCCAGCAGCGAAGCGTCCAGTGAGCCTCCTCATTTCTCCAGCTCTCACCTCGTCAGTAATTTCGCCATCGTGGAGAATCTGGATTTCCTGTACTTCCTGCGTCACGGACGGCCGGCCTTCGCTTACGCTGTTTACCTCACACAACACCTGAGAGACTGCAGTAACACTAAACTacaGTTGTCTATGGCAGTGGATCAGTCGTACTCATTGGCTCTGTTGAACTTCAGCAGTGCGAGTGTGTCGTCGgcgtgtgtgtgcttttgtgagCTCATGGGTGTGTGTAGCCTCAAACTGAGGACGGATCTGCGCACGCTGAACCTCATTCACAAGCACTGGAGTCAGAGCCGTGAGGACGGAGACGCAGATTTACTGCGACACACTCTGGTGGAGAAGGCCAGTCAGCTGATTAGCGCTGAGCATCGCACGGCTCAGGATCTGCTCCTCCATCTGGAAGCGGCCATCAGAGACGCTCTGGAGAAGAAGACCATCAGTCGCTGGTCGTTCGAGGCAGCACAGGAATGGGCACTTCCTGTCCAGTTCTGTCGACTCCACGCTCTTCCTCTAAGCTCCGCCTACCCGCTGGACTGCGCTCATGATGGACAGTGGCTGCACTTTCTGCTGTTCGTTCAGACGCACCAGTACCCGCCCCAACAGGTCAGGTTTCTATCTGAAAGCTTCAGTCCGGCTCTGCAGTCTCACATTTCTCTGGCCTTCCAGGATCTGCGTTCGCCAATAGAGGATCAGGGAGTCTCAGTGACTCCGCCCTCTCCAGACGAGAGCTCTGATTGGCCCACAGAGCTGTTCCAGGTGCTACTGCAGAGTCAGGAGAAGCCCCACCCCTGGAGGATCCTGCTGTCAGAGGCTGTGCGGCGCCGCTGTGCTCCTCTGGCCGTCCTCGCTGCCTCACACCAGGGCTCCGAGCTGCTGCAGTGCCTTTGTGTGTGGATCTTGACCTCggtggatgatgatgatgtcactcAGGAAGCTGCCGCCCACATCAACGAGAGCCCCGCCCACCACGTGTGGAACCTGCATGACCTGTCCATCCTCTGGAAGACGCTGCTGAGCCGCAGCAAGATCAGGCCTCTGATTCGCGGATTCCAGCTCTTTCAGAGGGAGTCTCCGCTGATTGCCATGCTTCAGATGTACGAGTTTTGCTTCGACTACAAAGACTATCAGAGAGCCAAAGACAAACTGCTGGACTTCCAGAAGAGTCTGCTTAATttgcgTAGCAGCAGTGTGTTGTCCAGCTCTGATGTTCTGCCAGTGCAGTGGGTGGAGTCTCAAGCTTCAGTGCTGCTCCTGACGCTCCTCAAGCAGAGCCGGACGCAGTATGAGCTCCGACGGCTGCTGCAGCTGCTGCTGCAGCTGCTGCTGGACGTGGAGAAACTGCTCAAGTCAAACGgtccaGATTTCCGGCTGCTCAGTGAGCTCAGTCAGCTGCTGTGTGAGACGCCGGTGTGTGTGTCGTCTCGTCTGCTTGACTGTTATTCCCCCAGTGTCCTGCAGGAGGAGTGTGTGAGGATCATGGAGGAGCTGCAGGACGCCGGACTCTACATGCAGGCGCGCAGAGTCGCAGAGCTGGCCGAGCTGcccgcacacacactcatcatcAACCAgcTTCTGCGGGATCTGAGCGCTCAGAAACTGAAGCGTCAGTGGGAGCGTCAGGAGATTCGATTGGCCTTCTGGAGGAGGTCACATGATCAGCTGCAGACCGAACACGTGCAGCCAGAGACCGCATGCCACTTCTTCCTCTCACAGGCCGAGGTGGCGCTGCAGTCAGACTCAGAGCTGGTGAATCTCCAGGAGCGCTGTGTTCTGCTGGGTTTAGCAGGACTCTGGTTGTCTCGCTGTGATCCTCCACCATCCACTCCAATTTTAGCAGATCTGGAGAAGCGTCAATGGGAATGTCGGATCCAGCAGCGACTCCTACTGGCAGATCTGGAGCGTCAGAGTCTGTTCGCTCCGTCCGCACTCTCCGAAGACTCTCCGGAAAATCTCCTGCGCGATTTTTCCTTCTCCAGAATGCCGGCTCTTAATGACGATGCTAATCTGAGTCTGGACGGTCTGCCGGCGGATTCAAATTCCTGTATTCTGCCTGAtgaccagcagagggcgctgGCGAGTCTGATCGCGCAGCTACTGAACGACGGCAGTGTGAACGAGGCTAGCCGTGTGTGTCGCTACTTCAGGTTTTTTCACAAAGATGTGTGGCTGGTGTTGCGGTGTCGCGGGTTAGCATGCGGCGAACTGCAGCCTGAACTTCACAGTCCTGATGGAGAGAGCCGCCGCAGTCTGCCGTCATctccCAGTATGAGCTCCCTGTCGTCGTTTGTGGTGGTGTCGTCTCCTGATGATCAGCTCCAGCTTCAGCTCCAGCTGCTGGTGGATCAGTGCAGCCACGGCAAGAGTTACTGCAAACAAGTGCTGAGCCTCTACCAGCTCTCCAAGgagCTGCAGTGCTCGTTCTCTGAGCTGTGGTCCTCTGAGCCGGAGTGTGTCCTGCAGAAGGTGCTTCTGTCTCGTCAGTCTGAGCGCTGTAAGAAAGCAGAGGCCTTCATCAGTGCTCAGAGTCTGCAGCCGCACACCGTCGCCAACCTCATCTCCACTGCAGTGCTGGAGGGACTGAACGCACACACACGAGACACTGACACtagtgagcGTCTGATTTTCAGTGCGTCGGACAGCAGAGAGTCGTTCCTCCAGCTCGCCAAACTGTGTGGAGACGCCAATCTGGTGGGAAACAAACTGCTGGACAGCATCGGCAGCGTCCCGCTGTCAGACCTCAGCTGCAtcgtGGAGCTGCTGATTCTGGCTCATGACTGCTTCAGTGTCACCTGTAATCTGGAAGGGATTGTTCGTGTTCTTCAGGCCTGCAGACACCTGAGCCACACACACCTGGCGCACGGAGACGCTCACGGCCTGCTGGTGCGTCTGCTCACAGGTATCGGCAGGTATAATGACATGACGTACGTCTTCGATCTGCTGCACCAGAACCACCGATTCGAGATGCTGCTGCGCAAGAAAGTGGAGtcgaATGTGCGTCTGAAGACGGCACTGCTGGATTATATCAAGCGTTGTCTGCCTGGCGACAGCGAGAAGCACAACATGGTGGCGCTGTGTTTCAGCATGTGCCGAGAGATCGGAGAAAACCACGAGGCGGCGGCCAGAACACAACTCAAACTCATAGAGTCTCAGCCCTGggtgatcACAGCAGAGCTGAAGAAGGCGTTAGTGAAGGTGCAGACGCTCCTCAAAGACGCAGCTGAGAGCTACTCAAAGgaCTCGTGTGTCCGTCAGGCTGTGCGCTGTGTGAAGCTGGCGAAGCTGGTGACTCTGCAGCTGCACTTCCTGAATCAGGGCCTGGAGCTGCGCATCATCAACCTGCAGCACACAGACCTGCAGAACACCAGCAACACACTGCCACACTGCTACCagGTGTTCGTGTTAGCAGAGGCGTATGACTTCAGTCCAGACTGGGCCGAGGTTTTCTATCAGAAGGTCATCATGAGAGGAGACTTCAGCTACCTGGAGGAGTTCAAGAGGCACAGGCCGCTAGCTGCTAGTCTCTTCCAGGACATCTCCAACAAGGTGTGTCATCAGAAGCCCCCCGCGAGCTGCAGTCAGCACCTGAAGAAGCTGCTGTCGCACTGTGAGGACGTCTACACGCATTATAAACTGGCCTACGAGCACCAGTTCCTGGACGTGGCCAACATGCTGCTGCAGGACTCCAAGACCAACAGCTTCCTGAAGGACCGCCTCCGCacctaaccagccaatcacagagcAGACACACCGGAGCTCATCAATATTCATGAGGACAGTCATTCATTAATAATGAGCAGTTATCATACACTAACAGCAGTGTTCAGAGTGTTCAGAAAATGCCTTAATCAAGAGTTTATATTAtatgtgtaaaaatataattaatataaaatgacTTTTTGATGATTTCAGACGTCAG
>TCONS_00048197
NTGGCGGATGGAGAGCTCTGTGTGGGGCTGAAAGACTGGCGGAGGGTGAAGCTGAGCGCGGGTCCGTCACTGCTGTGCTGCGTGAACGCGCAGGGGGAAACCAGTCTGAGGAACATCAGCGACAGCAGGGGAGCTGAGCATACACTACAGCACACCTGTGTAgaTTTCTTGTGGGAGGATGTGAGTGTGAGCAGCGGTGCACGTGTGAAGCCAAAGCTGCTGCTGCTAGACTCTGAGTTTTCTCTGCATATGTATGATGTGGATCAGGATGATCAGCCGACGCTGGTGTGTGAAACATCCTCTAATACACtgcttcagatcatcaaacacacacacgccgaCATGTGTGCTGTGGCGTCTGTGAGGCTGTTGTGTTTCTCTGAGGGCCGCTGTGTGTTGTTGGTGAACACGTgtgtgttgctgcagctcagactAACGGAGGACACACTAGAGCCCATATCCTGCTGCCGCCTCGGTGTGGAGTGTGTGGAGGAGTGTGTTGACTGCCGGCTGTGCAGAGGAGCACTCTTCATCCTCCTCAACAGCGGACTCTCATATGTGTTTGACAGCACTGACGGGCAGCTGTTGGCGAAGGTGGATTTTCCCTCATACTGCTGCAATGCTGGTGTTTCTCCATCCACCTCCTCCTTCTGTCTGCTCCAGATCTCTGCTGATCTCAGTACGGCTGTGAGCGTCACACGGCAGAACCAGGCCTACGCCGTACACCTCGACCACTACTTCAGtgtgtatCCCGATCACTTATACTGCCGTGCGGCCCCCATTCGTCCATTCCTCAGGCCTGTTGAATCCTGTGATCAGGACAGTCTCTCCAGCTCCACCCACAGTCTGTCAGTGCTGAATAAACCCCTGCAGGCCGACCGGTCATGGGAGTCTCGTCTGTCTGCGCTCTACAATCAAACTAAAGCTCCTGTTCGTCCCGTTTACATTTCACCCTGGTATAAAGACTTTCCTCACATCGAATGCCGTCGCGCAGCCGCTACAGCTAAACTCTGCCATTCCTCCGTGAAGACAGGGGGCGCCGTTATGTCTTTTAATGTGCCAGATGGAGCCACACCAGCAGGACTCAACGTGTCAGAGTTTTCAGCACTAATTACGTTCGTTTCTCCTGCTAACGCTAATACGGTTCTGGCCTACTGGGATCTGGAGAACGAAAGTGTGACGTATCATCGTGCAGATGCTAATGCTATTCCTGTGCAGAGATCAGCAGAGGAGAACCTGTGTCTATTACTGAAGGCGTCGGGTCTGTCGGTGGTGCTGTTCTGTGTTTCTCAGGACGAGCTGCTCAACAGACTGATGGTGTTCGGCAGCGCAGGAACAGTGGATTCACTCTGCCATCTGAACGCATGGGGGCGCTGTTCAATCCCTATACACgccctgcaggcggGTCTGAAGAACCATCAGCTGGACACAGTGGATTTCTTCCTGAAGAGTAAAGAGAACATCTTGAGTTCTTCATCCGGCTTCAGTCCAGGAGATCCTCCTCCGTCCTcctccaacacacacactcatctgcgGAgtatCGAAGCTCTGTGTCCTGCCCTGGATCTCCTGCGCTCTGCGATTCGCGACACACACACTGAAGCTCAGAGTCAACAGTTCTGTGAGCAGCTCTTGAGCATCACTATGAGCTTCCTGAACACACAGACCAGAGTCCTGCTGAGCGGAGCGCacggtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcatttagtACAGTCAGTAGACCCTCAGCTGCTCAGGATGGCTCTAAGtcagtatctctctctctctctctctctctctctctctctctctctctctctctctctctgtgtgtgtgtgtgcaggcggtCAGTACAGTGGACCCTCAGCTCCTCAGGATGGCTCTCCGTCAGTATCCTCAACTGAAGACAGCGCTGTTCCCTCAGAGCGGCCCTCGCGGAGATGTCTCGCTCTACCACCTGCTGCAGGTGCACACACTCACAGTATATACACCAGCATACTGTATattcacacacaaatatacacgaTGTAGATATATGcataatatatgtataaatatgtaccgtgtttttttatttagttttattaaagttATGAAAAAGCAGCAGTCAATTGTGAAGGTATCTCTTTTTAATGTTTCCCATATTTTAGTAaaTCAGCTGCTGTGTGAGACGCCGGTGTGTGTGTCGTCTCGTCTGCTTGACTGTTATTCCCCCAGTGTCCTGCAGGAGGAGTGTGTGAGGATCATGGAGGAGCTGCAGGACGCCGGACTCTACATGCAGGCGCGCAGAGTCGCAGAGCTGGCCGAGCTGcccgcacacacactcatcatcAACCAggtgaacagacacacacacacacacacacacacacacacacacacgacagatgcacacacacacacacacacacacacacacacacacacacacacacacacacagagacagacagCCGGAGTGTGTCCTGCAGAAGGTGCTTCTGTCTCGTCAGTCTGAGCGCTGTAAGAAAGCAGAGGCCTTCATCAGTGCTCAGAGTCTGCAGCCGCACACCAGAGTCGTTCCTCCAGCTCGCCAAACTGTGTGGAGACGCCAATCTGGTGGGAAACAAACTGCTGGACAGCATCGGCAGCGTCCCGCTGTCAGACCTCAGCTGCAtcgtGGAGCTGCTGATTCTGGCTCATGACTGCTTCAGTGTCACCTGTAATCTGGAAGGGATTGTTCGTGTTCTTCAGGCCTGCAGACACCTGAGCCACACACACCTGGCGCACGGAGACGCTCACGGCCTGCTGGTGCGTCTGCTCACAGGTATCGGCAGGTATAATGACATGACGTACGTCTTCGATCTGCTGCACCAGAACCACCGATTCGAGATGCTGCTGCGCAAGAAAGTGGAGtcgaATGTGCGTCTGAAGACGGCACTGCTGGATTATATCAAGCGTTGTCTGCCTGGCGACAGCGAGAAGCACAACATGGTGGCGCTGTGTTTCAGCATGTGCCGAGAGATCGGAGAAAACCACGAGGCGGCGGCCAGAACACAACTCAAACTCATAGAGTCTCAGCCCTGggtgatcACAGCAGAGCTGAAGAAGGCGTTAGTGAAGGTGCAGACGCTCCTCAAAGACGCAGCTGAGAGCTACTCAAAGgaCTCGTGTGTCCGTCAGGCTGTGCGCTGTGTGAAGCTGGCGAAGCTGGTGACTCTGCAGCTGCACTTCCTGAATCAGGGCCTGGAGCTGCGCATCATCAACCTGCAGCACACAGACCTGCAGAACACCAGCAACACACTGCCACACTGCTACCagGTGTTCGTGTTAGCAGAGGCGTATGACTTCAGTCCAGACTGGGCCGAGGTTTTCTATCAGAAGGTCATCATGAGAGGAGACTTCAGCTACCTGGAGGAGTTCAAGAGGCACAGGCCGCTAGCTGCTAGTCTCTTCCAGGACATCTCCAACAAGGTGTGTCATCAGAAGCCCCCCGCGAGCTGCAGTCAGCACCTGAAGAAGCTGCTGTCGCACTGTGAGGACGTCTACACGCATTATAAACTGGCCTACGAGCACCAGTTCCTGGACGTGGCCAACATGCTGCTGCAGGACTCCAAGACCAACAGCTTCCTGAAGGACCGCCTCCGCacctaa

Function

symbol description
spg11 Acts upstream of or within axonogenesis; swimming behavior; and thigmotaxis. Predicted to be active in several cellular components, including axon; dendrite; and synapse. Is expressed in muscle; nervous system; notochord; and trunk. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin).

GO:

id name namespace
GO:0048489 synaptic vesicle transport biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0007399 nervous system development biological_process
GO:0048675 axon extension biological_process
GO:0007409 axonogenesis biological_process
GO:0008088 axo-dendritic transport biological_process
GO:0036269 swimming behavior biological_process
GO:0001966 thigmotaxis biological_process
GO:0030424 axon cellular_component
GO:0030425 dendrite cellular_component
GO:0045202 synapse cellular_component
GO:0005737 cytoplasm cellular_component

KEGG:

id description
ko05014 Amyotrophic lateral sclerosis
ko05022 Pathways of neurodegeneration - multiple diseases
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-101017-1 Acts upstream of or within axonogenesis; swimming behavior; and thigmotaxis. Predicted to be active in several cellular components, including axon; dendrite; and synapse. Is expressed in muscle; nervous system; notochord; and trunk. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin).

Ensembl:

ensembl_id ENSDARG00000045968

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00048196 False 5032 mRNA 0.56 28 1088693 1124851
TCONS_00048197 True 3640 mRNA 0.54 21 1088886 1126311

Neighbor

gene id symbol gene type direction distance location
XLOC_024373 FO907089.1 coding downstream 9276 1047627 ~ 1079417 (-)
XLOC_024372 znf609a coding downstream 90597 821725 ~ 998096 (-)
XLOC_024371 irak4 coding downstream 314222 768014 ~ 774471 (-)
XLOC_024370 tmem117 coding downstream 336535 710139 ~ 752158 (-)
XLOC_024369 NA coding downstream 445587 630933 ~ 643106 (-)
XLOC_024375 CU861469.1 coding upstream 68971 1195282 ~ 1196112 (-)
XLOC_024376 coro2bb coding upstream 93968 1220279 ~ 1235457 (-)
XLOC_024377 calml4b coding upstream 140634 1266945 ~ 1323928 (-)
XLOC_024378 cln6b coding upstream 199635 1325946 ~ 1334504 (-)
XLOC_024379 itga11b coding upstream 216850 1343161 ~ 1426876 (-)
XLOC_024366 NA non-coding downstream 632215 455319 ~ 456478 (-)
XLOC_024363 NA non-coding downstream 724925 360538 ~ 363768 (-)
XLOC_024361 NA non-coding downstream 783036 305008 ~ 305657 (-)
XLOC_024360 NA non-coding downstream 794084 287659 ~ 294609 (-)
XLOC_024380 CR354429.1 non-coding upstream 338068 1464379 ~ 1471185 (-)
XLOC_024381 NA non-coding upstream 498569 1624880 ~ 1625918 (-)
XLOC_024382 dre-let-7i non-coding upstream 503344 1629655 ~ 1629749 (-)
XLOC_024385 NA non-coding upstream 820057 1946368 ~ 1951444 (-)

Expression


Co-expression Network