XLOC_024399 (best1)



Basic Information


Item Value
gene id XLOC_024399
gene name best1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 3069671 ~ 3087556 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00048242
ATGACGGTGACGTACTCGCGGCGGGTGGCAGATGCGCGTCTGGGCACCTTTTATCGCCTTCTTCTGCGATGGAAAGGAAGCATTTATAAGCTGCTGTATCGCGAGCTGCTGATCTTCACTGTGATGTACTGCATTATCAGCATCACATACAGgtgtGTACTGACTGAAGAGCAGCGCAGGATGTTTGAGAAGCTCTCCCTGTACTGTGATCAGTACGCTCAGCTCATTCCTGTGTCATTCGTACTGGGTTTCTATGTGACTCTGGTGGTGTCCCGCTGGTGGGGTCAGTTCGAGAGCGTCCCCTGGCCGGACCGCCTGTCAGCTCTGGTCAGTGGACATGTACGGGGTGCAGATGAAGGAGCCAGACTCATACGCAGGAGTTTAATGCGCTACGCAAACCTGTCCGGCATCCTCATCTACCGCTCCGTCAGCACGGCTGTCTACAAGAGATTCCCGACCATGAGCCACTTGGTTCAAGCAGGTCTGATGACAGCGGAGGAGCTGAGGCAGCTGCAGGAGCTTCCTTCACCTCATAATAAGTTCTGGGTTCCCTGCATGTGGTTTGTCAGTCTGGCTATGAGAGCTCGATCTGAAGGACGAATCAATAACGACGTCGCAATGACAGCCATCCTCAACGAACTGAACACGCTTCGGTCTCAATGTATGAGGCTGTACGGATATGATTGGATCAGCTTACCTCTCGTTTATACACAGGTGGTAACCGTGGCTGTGTACAGTTTCTTTTTGACTTGTCTGATTGGTCGGCAGTTTCTTGACCCCGCCCAGGGTTACCCGGGTCACAACCTCGACTTCTACCTGCCTGTCTTCACTTTACTCCAGTTCTTCTTCTACGTGGGCTGGCTTAAGGTTGCAGAGCAGCTTATTAATCCATTTGGGGAGGATGATGACGACTTTGAGACTAACTGGCTGGTGGACCGTAATTTACAGgtGTCTCTGCTGTCAGTGGATGAGATGTATGATCTGGTTCCTCTGGTTGAGAGAGATAAATACTGGGATGAAGCTGAGCCTCAGCCGCCGTACACCGCCGCCAGCGCAGAACACCGCAAACCCTCATTCATGGGATCTGCGCTGGACATCAGcGTTCCTAAAGAGGAAATGGAATTCCAGCACAATCTGGAGCAGATTAAAGAGCACGAGGAGGCCAATCACTCCACTCCATTCCTGGGCAGCTTGAGTCGACTTCTGGGCGTTCAGTCGCCCAATTTCCCCCGCTCGACCCCTACATCAAGAGTCTCCCTCCTGCGACGCCGACCCCGTGCTCCGTTCTCTCGTTTCCCACTTTACCTCCATTCTGAGAGCTCACAGATGCCCAGCCACAGTCGCAACACGGATGTGAGCGAGGACGCCTTTTCAGCAATGCCTCTGTATGAACGACCCGGTTTTTACAGCTGCCCCCAAACGCCCATCCACTGCATCCCTCCACCCGTTCCACGACCAAGACCACGGAGAGCGCATGGTGACAGCTCCAGCTCCTTAACACAACCTATGGTGGGCTCACAAATCCTGGCTCTGCCTGACACACCCGCACCTCCTTCATCCGCCTTCCCTTGGGTGGGGGAAGACAGCGAACATCCGGCGTTCTCCTTTCCAGATCCTGTCCCTGAAATATGTCCGTTAACCAAAGCACGACTAATTCAAGGCTTACCATCGCGCCGTCCTCTCCCTCTGCGACTATCTGTCGATAAATCTCCATCTCCATCTACACCAGAGAGGGTGTTTTCATTCACACCGCCATCTTGGCCGCAAACGCAAATCAACACCGCTAGTTCAGTGAATGTGAACGtgacaaatagtaataataatctgTGCAACGGCACAGCAAACAACCCCTGGCCAATCAGCAGAAGCAGCAATGCAAGCACAGCCAATCCTGTCAGCACGAGCCCTACGGCGACTCAGCACTCAGCCAATCAGCAGAACTCTCCCAACGATTCTGGAATCTCATTGGCTGACGGGGATCTGTTGGGCGCAGCTGTGAAAACAAGGGAACAGCTCTAA
>TCONS_00048243
GTCTGATGACAGCGGAGGAGCTGAGGCAGCTGCAGGAGCTTCCTTCACCTCATAATAAGTTCTGGGTTCCCTGCATGTGGTTTGTCAGTCTGGCTATGAGAGCTCGATCTGAAGGACGAATCAATAACGACGTCGCAATGACAGCCATCCTCAACGAACTGAACACGCTTCGGTCTCAATGTATGAGGCTGTACGGATATGATTGGATCAGCTTACCTCTCGTTTATACACAGGTGGTAACCGTGGCTGTGTACAGTTTCTTTTTGACTTGTCTGATTGGTCGGCAGTTTCTTGACCCCGCCCAGGGTTACCCGGGTCACAACCTCGACTTCTACCTGCCTGTCTTCACTTTACTCCAGTTCTTCTTCTACGTGGGCTGGCTTAAGGTTGCAGAGCAGCTTATTAATCCATTTGGGGAGGATGATGACGACTTTGAGACTAACTGGCTGGTGGACCGTAATTTACAGgtGTCTCTGCTGTCAGTGGATGAGATGTATGATCTGGTTCCTCTGGTTGAGAGAGATAAATACTGGGATGAAGCTGAGCCTCAGCCGCCGTACACCGCCGCCAGCGCAGAACACCGCAAACCCTCATTCATGGGATCTGCGCTGGACATCAGcGTTCCTAAAGAGGAAATGGAATTCCAGCACAATCTGGAGCAGATTAAAGAGCACGAGGAGGCCAATCACTCCACTCCATTCCTGGGCAGCTTGAGTCGACTTCTGGGCGTTCAGTCGCCCAATTTCCCCCGCTCGACCCCTACATCAAGAGTCTCCCTCCTGCGACGCCGACCCCGTGCTCCGTTCTCTCGTTTCCCACTTTACCTCCATTCTGAGAGCTCACAGATGCCCAGCCACAGTCGCAACACGGATGTGAGCGAGGACGCCTTTTCAGCAATGCCTCTGTATGAACGACCCGGTTTTTACAGCTGCCCCCAAACGCCCATCCACTGCATCCCTCCACCCGTTCCACGACCAAGACC

Function


symbol description
best1 Predicted to enable chloride channel activity. Predicted to act upstream of or within chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy; bestrophinopathy; macular degeneration; retinitis pigmentosa 50; and vitelliform macular dystrophy. Orthologous to human BEST1 (bestrophin 1).

GO:

id name namespace
GO:1902476 chloride transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006821 chloride transport biological_process
GO:0034707 chloride channel complex cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005254 chloride channel activity molecular_function

KEGG:

id description
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-110411-214 Predicted to enable chloride channel activity. Predicted to act upstream of or within chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy; bestrophinopathy; macular degeneration; retinitis pigmentosa 50; and vitelliform macular dystrophy. Orthologous to human BEST1 (bestrophin 1).

Ensembl:

ensembl_id ENSDARG00000078331

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00048242 False 2019 mRNA 0.53 9 3069671 3087556
TCONS_00048243 True 982 mRNA 0.53 6 3070227 3079214

Neighbor


gene id symbol gene type direction distance location
XLOC_024398 si:ch1073-296i8.2 coding downstream 10949 3047129 ~ 3058722 (-)
XLOC_024397 scamp2 coding downstream 35003 3015676 ~ 3034668 (-)
XLOC_024396 adpgk coding downstream 345638 2706722 ~ 2724033 (-)
XLOC_024395 BX957346.3 coding downstream 383689 2672491 ~ 2685982 (-)
XLOC_024394 BX957346.1 coding downstream 430854 2546343 ~ 2638817 (-)
XLOC_024400 epx coding upstream 32254 3119810 ~ 3139805 (-)
XLOC_024401 hps5 coding upstream 60875 3148431 ~ 3192405 (-)
XLOC_024402 gtf2h1 coding upstream 109299 3196855 ~ 3217115 (-)
XLOC_024403 cib1 coding upstream 136529 3224085 ~ 3230187 (-)
XLOC_024404 pthlhb coding upstream 170376 3257932 ~ 3262318 (-)
XLOC_024393 NA non-coding downstream 584623 2483112 ~ 2485048 (-)
XLOC_024391 NA non-coding downstream 756638 2309414 ~ 2313033 (-)
XLOC_024390 NA non-coding downstream 769922 2275525 ~ 2299749 (-)
XLOC_024405 NA non-coding upstream 214968 3302524 ~ 3306305 (-)
XLOC_024407 NA non-coding upstream 290267 3377823 ~ 3393705 (-)
XLOC_024410 NA non-coding upstream 442911 3530467 ~ 3531168 (-)
XLOC_024415 NA non-coding upstream 658608 3746164 ~ 3747949 (-)
XLOC_024421 NA non-coding upstream 793166 3880722 ~ 3884430 (-)

Expression



Co-expression Network