XLOC_024795 (isl2a)


Basic Information

Item Value
gene id XLOC_024795
gene name isl2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007136.7
NCBI id CM002909.2
chromosome length 37502051
location 32746014 ~ 32751982 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00048866
CGGGACGAGGCAGTTTCCCATTCCATTTCCTCATCTGTAGCCTTCTGCCTTAACCCTCCTGTATGGTGGATATTCTACCGCATCCTTCTTTCTTGGGTGATATGGGGGATCATTCAAAAAAGAAGTCTGGAATCGCCATGTGTGTCGGCTGTGGAAGTCAGATCCATGATCAGTACATACTGCGGGTGTCCCCGGACCTGGAGTGGCACGCAGCCTGTCTGAAGTGCGCAGAAtgcagtcagtacctggatgagacGTGCACTTGCTTCGTCCGAGACGGCAAGACTTATTGCAAGAGAGATTACGTACGATTATTCGGGATCAAATGCGCCAAATGTAACATCGGTTTCTGCAGCAGTGACCTGGTCATGAGGGCCCGGGATAACGTCTACCACATGGAGTGTTTTAGGTGCTCGGTGTGCAGCAGACATTTGCTCCCGGGAGATGAGTTCTCATTGCGGGACGAGGAGCTGCTCTGCCGGGCGGACCACGGACTGCTAATGGAACGCGCTTCCGCTGGGAGCCCCATCAGCCCGGGGAACATTCACTCTAGCAGGCCCTTACACATCCCAGAACCTGTGCCAGTTCGACAGCCACCTCATCGGAATCACGTTCACAAGCAGTCGGAGAAAACCACGCGTGTTCGGACAGTATTAAACGAAAAGCAGCTTCACACCCTCCGGACGTGTTATAATGCAAACCCTCGACCGGACGCGCTAATGAAAGAGCAGCTCGTGGAAATGACCGGCCTGAGCCCACGGGTCATACGAGTGTGGTTCCAAAACAAACGCTGCAAAGACAAGAAGAAGTCCATACTCATGAAACAACTACAGCAACAGCAACACAACGACAAAACGAATCTCCAAGGTCTCACGGGAACGCCTTTGGTGGCAGGCAGCCCGATTAGACATGACACCACAGTCCAGGGAAATCCTGTAGAAGTTCAAACCTATCAGCCTCCATGGAAAGCCTTAAGCGAATTTGCCTTACAGAGCGACCTGGACCAGCCTGCTTTCCAACAGCTGGTGTCATTTTCCGAGTCGGGTTCGCTGGGTAACTCGTCTGGTAGTGATGTGACCTCTCTGTCATCGCAGTTACCCGACACCCCCAACAGCATGGTGCCCAGTCCCGTGGAGACGTGAGAGCCCACCGGAGACTCCTGCCCCAGCATGCCCTCACCCGCCCTGCATGAAAACCCATCACCTCACCGCCTCAAACGGAAAAAAGGGATTAACCGAGATGGATTTAAACAGTTTGCCAAACGGAGGAGCCTGTCCAAGCGACTTTGGGGTTTCCAGACGTGTTACAAAACTGTTTCTTAAGCATTTGGACCGTGTATCGAGGATCGTCCAGCGGAATATGAACACGTTATTTTGGTTTTGAATATGGACTACTGTCAACCTTACGAAAGCAACAGTCTTAACAGTGTTTATTCAAGACCATCCTTGTGTAGCTTTATCAACAAGTGGTATTTTCCTCATGAGacaaaaatcagatttttttgtcttgatgCGCATGATCTCCGAAGATGTATAAAACTgagctgtaaaatattttatcttaACAAATGGAGGACAGATTGTATAAACTTCTCGATTTAAAAAAGtaagttattgttatttattgtcaGGACAACCGTCCATACCAAAAAGTgagaaattacataaataaacgacgttaaaatgc

Function

symbol description
isl2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within blood vessel morphogenesis; exocrine pancreas development; and neuron differentiation. Predicted to be active in nucleus. Is expressed in several structures, including ectoderm; gut; liver and biliary system; nervous system; and neural tube. Orthologous to human ISL2 (ISL LIM homeobox 2).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0031017 exocrine pancreas development biological_process
GO:0007275 multicellular organism development biological_process
GO:0048845 venous blood vessel morphogenesis biological_process
GO:0048665 neuron fate specification biological_process
GO:0048675 axon extension biological_process
GO:0007409 axonogenesis biological_process
GO:0007411 axon guidance biological_process
GO:0035476 angioblast cell migration biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-562 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within blood vessel morphogenesis; exocrine pancreas development; and neuron differentiation. Predicted to be active in nucleus. Is expressed in several structures, including ectoderm; gut; liver and biliary system; nervous system; and neural tube. Orthologous to human ISL2 (ISL LIM homeobox 2).

Ensembl:

ensembl_id ENSDARG00000003971

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00048866 True 1686 mRNA 0.49 6 32746014 32751982

Neighbor

gene id symbol gene type direction distance location
XLOC_024794 NA coding downstream 215146 32518399 ~ 32530868 (-)
XLOC_024793 atp8b4 coding downstream 281865 32404938 ~ 32464149 (-)
XLOC_024792 cops2 coding downstream 364351 32366071 ~ 32381663 (-)
XLOC_024791 cep152 coding downstream 382663 32315319 ~ 32363351 (-)
XLOC_024790 zgc:101540 coding downstream 434958 32294719 ~ 32311056 (-)
XLOC_024796 tmem266 coding upstream 35381 32787363 ~ 32869794 (-)
XLOC_024797 c2cd4a coding upstream 134161 32886143 ~ 32888115 (-)
XLOC_024798 NA coding upstream 252245 33004227 ~ 33007045 (-)
XLOC_024799 NA coding upstream 434891 33186873 ~ 33202190 (-)
XLOC_024800 CABZ01046954.1 coding upstream 514604 33266586 ~ 33275666 (-)
XLOC_024789 CR847962.1 non-coding downstream 725019 32020881 ~ 32020995 (-)
XLOC_024783 CU651671.1 non-coding downstream 1067821 31678079 ~ 31678193 (-)
XLOC_024780 NA non-coding downstream 1242545 31500307 ~ 31503469 (-)
XLOC_024776 CU462909.1 non-coding downstream 1427886 31318012 ~ 31318128 (-)
XLOC_024801 NA non-coding upstream 682430 33434412 ~ 33435148 (-)
XLOC_024802 NA non-coding upstream 998817 33750799 ~ 33762426 (-)
XLOC_024803 NA non-coding upstream 1187131 33939113 ~ 33952194 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000330_02272290_02277018 ISL2, ISL2A coding CI01000330 null 2271765 ~ 2277874 (-)
bowfin (Amia calva) AMCG00007786 LOC102216635,LOC103354952,LOC105930457,LOC105022634,LOC104917923,LOC106945593,LOC103149886 coding CM030123.1 CM030123.1 29574334 ~ 29585227 (-)