XLOC_002494 (glis3)


Basic Information

Item Value
gene id XLOC_002494
gene name glis3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 644574 ~ 690170 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004662
GGAAAACTCCACTTAAACACGGTAAAAACCCTCTTGAAACACCGTATAAGCCCTCATGTGAGGGTATCGATCCCGATGACGTCACGGCGGCAGAGGCGCGCGCCCCGGAGCGGTTTATTTCCCGCAGCAGGTGTCCTGACGAGGCTTTAACAGGATCCTGATATATGAATCTGAAGGCCATGTTTTGTGATGGACATGAATGGGAAAGGCTGTAACCTGATGGTTTCTCCGTCCGGCATGGCTCAGATATCTCCGCTGAAGGTCCACACTCCTGCATCTCTCTATCCAGAATCAAACTCAGCTCAGAGTCTCCGCCGGCAGGTGCTCACCAATGGAAAACTGGGCTTTCCACAGCCATCCCGAGCTCTTCATCAACAGGCTCCACAGATTTCACTCCCAGCATCCTCCTCCTCCAAACAGTCTGCTCGACAATGCTGTCAGGACAGCGGTATGAAAGGTTACAGAAGGGTGTTTGGGTCGTGTGGCAGCTCAAACCTGCAGGTCTCCAGCAGTGCTTTTCTGGTCCAGAGTCTCAGTCCTGCTTCTGCATCCGTCACACACTCCTCATCACAAACCTGCCCGCAGAATACACTCACACTGCCCTTCAATGACGCCAGCAGGTGTTTGCTCTCCAGAGAGTCTCTGGCCTCCACCACCCTTAGTCTGGCTGAGACTCAGTCTGTGCGCAGCAGTAAACTGGACTGGCCGTACGGCTACAGGGTCCTTCCTCCACTAGGCCACCAAACAGCCAATCAGTTGTCAGAATCCACTGTCCCTGAATCCTCCCTATCCGAAAGCGTCTCCAACCCTGCATCTCTCCCTCATTACCTCTTCAAGGAAGACGGCAGTAGTCCGCGCCTCTCGGCCCGCTCAAAGAAGCGAGCGCTGTCTTTATCCCCACTATCGGATGGTTTGGGCCTGGACCTGAACTCCATCATCCGCACCTCGCCTACATCTCTGGTGGCCTACATCATCGGCTCCAGGATCTCACCAGCGTCCCACAACACCCCGTCCCCACTGCAGGCGGACGTCTGTGGGCATCTGCTGGGCATCAGGGGCAGCGGCATCCCTACATCCAGCAAACATAGCATCTCCGTCAGCGAGAGCCTCCGCATGCAGCCGCTGGAGGACCAGTTCACCAACCTACTAGTGGAGCAGCAGATCCTGCCAGACCCACAAACTGCAAAGGCCAGTCAGACCCATACGCTTCAGTTTGAGGTGTCCAGGATTGTCCGGTCCCCCAGCCCACCCCGGGGGCCACCACCGCCCTACAGCgcccaccaccagcagcagcagcagccacGGGTTTTGCAGCTCCAACGGCCGGCGGGGCTTCAGCCGATgctggaggaggaggaagaagaggaagagtCCTGCGGCGGGACACACTGCTGCTGCTGGCTGCACTGCGGAGCCATCTACAGCCACCGGGACGCGCTGGTCAAACACATCGAGAAGATCCACGTGGACCAGCGCAAAGGAGAGGACTTCACCTGCTTCTGGGCTGGCTGCGCGCGCAAACACAAACCCTTCAACGCACGCTACAAACTGCTGATCCACATGAGGGTGCACTCGGGGGAGAAGCCCAACAAGTGCTCGTTCGAGGGCTGTCAGAAGGCGTTTTCCCGCCTGGAGAACCTGAAGATCCACCTGAGGAGCCACACGGGTGAGAAACCCTACGTGTGTCCACATCCCGGCTGCCTGAAAGCCTTCAGCAACTCCAGCGACAGAGCCAAACACCAGCGCACGCATGTGGACACGAAACCGTACGCGTGTCAGATCCAGGGCTGTGGAAAGCGCTACACCGACCCCAGCTCACTGCGGAAACACGTCAAATCTCACTCGCTGAAGGAGCAGCAGGCCCGGAAGAAGTTGAGACGCAGCTCAGATCTCAGTCAGGACGGACTCAGCGAGTGTTTGACGGTTCAGCCGCTGCAGCACAGCCTCTCCACACTGGACCTGATTGAGAGCAAGCACCACTCACCCACAGATGACCTCTACACCGTCTTCACCCTGAACCAGCCGAGCCAAACAAACACCCTGAACAGCCCAATGCAGATCGCAGGCGGTCCACAGACTCATCAAAGTCCTCATCAGACTCACCAGGCTCATCAGATCCATCAGACTCAGACTCATCTGACTCACCAGACCCATCAGGCTCACCAGACTCAGACTCATCACATCCAGCAGATTCATCAGACTCACCTGACTCATCAGATCCAGCAGATTCACCAGACTCATCTCTCTCCACATGGAGCACTGCCACCATTACAGGGAAACAACAGGTTTCTCAGCCCGAACAGCCACAAAGCTCCGGGATTCTGCAGTCAGCCCAGGACATCTGCTCAGGACGGTTTCTCGGCTGTGTTTTCATACGCCGACTCAGACAAACACATCTCCTCCTGCTCCGTCATGCAGACGCCCATGTTTGAGGACAATCTCAGCTCGTCGCCTCAGATCCACAGCAACATCTccgTGCTGGACTGCCAGAGCGGCCCTCAAGGCTTTATAGGAGAGCAGGAGCCCTCAGTGTCGGAGGACAATTATCTTCACATCCCGAGATGTCCGAGCCGGATCTCCTGTGTGTTCACTGAAGGCTGAGCGTCTCCGCCACACACTGCAAAATGCCTTTACCTACAGTTTCTGTCTGGATTCCAGTCCAAATACCAGGAAGCGTTTTCTTTCCAGTGCTTCTACAAGAATGtatattacatttcattaaacagcacttggg

Function

symbol description
glis3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within glucose homeostasis; pancreas regeneration; and type B pancreatic cell development. Predicted to be active in nucleus. Is expressed in several structures, including brain; endoderm; otic vesicle; pectoral fin bud; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in neonatal diabetes mellitus with congenital hypothyroidism. Orthologous to human GLIS3 (GLIS family zinc finger 3).

GO:

id name namespace
GO:0042593 glucose homeostasis biological_process
GO:1990798 pancreas regeneration biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0003323 type B pancreatic cell development biological_process
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070112-2232 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within glucose homeostasis; pancreas regeneration; and type B pancreatic cell development. Predicted to be active in nucleus. Is expressed in several structures, including brain; endoderm; otic vesicle; pectoral fin bud; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in neonatal diabetes mellitus with congenital hypothyroidism. Orthologous to human GLIS3 (GLIS family zinc finger 3).

Ensembl:

ensembl_id ENSDARG00000069726

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004662 True 2734 mRNA 0.56 12 644574 690170

Neighbor

gene id symbol gene type direction distance location
XLOC_002493 rfx3 coding downstream 2965 600164 ~ 641609 (-)
XLOC_002492 NA coding downstream 96373 546202 ~ 548201 (-)
XLOC_002491 NA coding downstream 222921 415997 ~ 421653 (-)
XLOC_002490 CU929346.1 coding downstream 270999 360237 ~ 373575 (-)
XLOC_002489 NA coding downstream 285867 356555 ~ 358707 (-)
XLOC_002496 bmpr1bb coding upstream 392791 1082961 ~ 1180314 (-)
XLOC_002497 pdlim5b coding upstream 497483 1187653 ~ 1276046 (-)
XLOC_002498 opn4xa coding upstream 604293 1294463 ~ 1320114 (-)
XLOC_002499 NA coding upstream 733071 1423241 ~ 1433140 (-)
XLOC_002500 WDR70 coding upstream 744786 1434956 ~ 1523289 (-)
XLOC_002488 NA non-coding downstream 289917 354093 ~ 354657 (-)
XLOC_002487 CABZ01049604.1 non-coding downstream 304547 339912 ~ 340027 (-)
XLOC_002501 CABZ01066320.2 non-coding upstream 851093 1541263 ~ 1544095 (-)
XLOC_002502 CABZ01066320.1 non-coding upstream 853993 1544163 ~ 1552789 (-)
XLOC_002504 NA non-coding upstream 976172 1666342 ~ 1667630 (-)
XLOC_002505 NA non-coding upstream 978974 1669144 ~ 1718637 (-)

Expression


Co-expression Network