XLOC_002496 (bmpr1bb)



Basic Information


Item Value
gene id XLOC_002496
gene name bmpr1bb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 1082961 ~ 1180314 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00004663
ATGGAGCTCCGGGTACGGACGGGAAACGAAAAGTTCTGGACGTTGATTCTGCTGGGCGTCTTGTGGATTTATTCGTCCGCTCACGCGAACGTGCTGGACACCATGTTACAGAGGAGTTCTGGAAAGGTAACGGCGGGCCGGAAGGAGACCAACGGCGGCAGCGCAACTTCTGTGATTCCAGAGAGGATGTTATTATGCCACTGTTACCATCACTGTCCTGAAGATTCAACCAATAATACCTGCAGgACTGATGGTTACTGCTTCACTATGGCGGAGGAAGAGGAAGGAGGCTCGCCTGTGCTCACATCAGGATGTCTGTCTTTAGTGGGGTCAGAGTTTCAGTGCAGGGACACTGGAAACGCTCGTCTGAGGAGGATCCTGGAATGCTGCACCGATCAGGATTACTGCAACCAAGACCTTCATCCGACACTGCCTCCGCTCAAGACACCCGAAATTagCAAGAGTGTCATATATAAAGCTCTGTGTGTTGCTGTGATGTTGTtgtgtgtgtgtgtgtttgtgtttatgtttgtatgtatgtttatgtacAGGCGTCAGGGCACACAGACGCGCTACAGTATGGGTCTGGAGCAGGACGAGAGCTTCATTCCTGCTGGAGAGTCTCTGAAGGATCTGATCGAGCAGTCGCAGAGCTCCGGCAGCGGATCCGGACTCCCTCTGCTGGTGCAGAGGACCATCGCCAAGCAGATCCAGATGGTGAAGCAGATCGGGAAGGGCCGCTACGGGGAGGTGTGGATGGGCCGCTGGAGGGGCGAGCGGGTGGCTGTGAAGGTCTTCTTCACCACAGAGGAGGCCAGCTGGTTCAGGGAGACCGAGATCTACCAGACCGTCCTGATGAGACACGAGAACATACTGGgctTCATCGCAGCAGATATTAAAGGCACGGGCTCGTGGACGCAGCTGTACCTGATCACGGATTATCACGAGAGCGGCTCGCTGTACGACTACCTGAAGTCCACCACGCTGGACACGCGCGCGCTGCTGCGGCTCTCGTACTCCGCCGTCTCCGGCCTCTGCCATCTGCACACTGAGATCTTCGGCACGCAGGGGAAACCGGCCATCGCCCACCGAGACCTGAAGAGCAAAAACATCCTGGTCAAGAAGAACAGCACCTGCTGCATCGCTGACCTCGGCCTCGCTGTCAAGTTCATcagtgacaCTAACGAAGTGGACATCCCTCCAAACACGCGTGTGGGCACCAAACGCTACATGCCTCCAGAGGTGCTGGACGAGAGTCTGAACCGCTGCCACTTCCAGTCCTACATCATGGCGGACATGTACAGCTTCGGCCTGATCCTGTGGGAGATCAGCAGGAGATGTGTGTCTGGcgGCATCATGGAGGAGTATCAGCTGCCGTATCATGACCTGGTTCCCTCAGACCCATCATATGAGGACATGCGGGAGGTGGTGTGTATCAAGAGGCAGAGACCCTCTTTTGCCAACCGCTGGAGCAGTGATGAGTGTCTGAGGCAGATGGGTAAACTGATGAGCGAGTGCTGGGCTCATAATCCTGCGTCACGGCTGACAGCGCTGCGGGTCAAGAAGACGCTCGCCAAGATGTCAGAGTCGCAGGACATTAAACTGTGA
>TCONS_00004664
GGACCGCAGAGAATGAAGATGTTGACAGATCTGAACATCATAAATTCCTGAGGAGCTTCTTCATTCGTCTGCAGATTGAGGTGTGTGAGCGTCAGTGGAGGGCAGATGATCATAAACACGGACTGAGTGACACACAGGCTGCCGTCAGTGTGGAGTAGCTgtggagcagtgtgtgtgtgtgtgagagtgtttccATGCCCCGGTGGTGCGGGCGGCCGGCTCCAGTCTCAGGGATGGAGCTCCGGGTACGGACGGGAAACGAAAAGTTCTGGACGTTGATTCTGCTGGGCGTCTTGTGGATTTATTCGTCCGCTCACGCGAACGTGCTGGACACCATGTTACAGAGGAGTTCTGGAAAGGTAACGGCGGGCCGGAAGGAGACCAACGGCGGCAGCGCAACTTCTGTGATTCCAGAGAGGATGTTATTATGCCACTGTTACCATCACTGTCCTGAAGATTCAACCAATAATACCTGCAGgACTGATGGTTACTGCTTCACTATGGCGGAGGAAGAGGAAGGAGGCTCGCCTGTGCTCACATCAGGATGTCTGTCTTTAGTGGGGTCAGAGTTTCAGTGCAGGGACACTGGAAACGCTCGTCTGAGGAGGATCCTGGAATGCTGCACCGATCAGGATTACTGCAACCAAGACCTTCATCCGACACTGCCTCCGCTCAAGACACCCGGTTAAACTGTTACAAACCGCAGGATTGGTGCTGCAGGGGCTGCTGGGGTTGAGCGTGTTTCTGCCGCTCTAATGAAAAGGACACGAGACCTCACGGGAGCGCTTGAGTTTCTgatatctgtccatctgtcacAGTGAGACACctcagagagagagtgtgtgtgtgtgtatgtgtgtgtgtgtgtgtgtgatgaaaagAAAAGTGCTGTTCATTGTTGCTGTCGTGCTAATATTTATGACTCCTTTTTTT

Function


symbol description
bmpr1bb Predicted to enable SMAD binding activity and transforming growth factor beta receptor activity, type I. Acts upstream of or within BMP signaling pathway; dorsal/ventral pattern formation; and germ-line stem cell division. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including head; immature eye; liver; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in brachydactyly type A1D; brachydactyly type A2; and osteochondrodysplasia. Orthologous to human BMPR1B (bone morphogenetic protein receptor type 1B).

GO:

id name namespace
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway biological_process
GO:0042078 germ-line stem cell division biological_process
GO:0071363 cellular response to growth factor stimulus biological_process
GO:0030509 BMP signaling pathway biological_process
GO:0006468 protein phosphorylation biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0016310 phosphorylation biological_process
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0043235 receptor complex cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0046332 SMAD binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004675 transmembrane receptor protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function
GO:0005025 transforming growth factor beta receptor activity, type I molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090610-1 Predicted to enable SMAD binding activity and transforming growth factor beta receptor activity, type I. Acts upstream of or within BMP signaling pathway; dorsal/ventral pattern formation; and germ-line stem cell division. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including head; immature eye; liver; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in brachydactyly type A1D; brachydactyly type A2; and osteochondrodysplasia. Orthologous to human BMPR1B (bone morphogenetic protein receptor type 1B).

Ensembl:

ensembl_id ENSDARG00000102742

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00004663 False 1608 mRNA 0.55 15 1082961 1133162
TCONS_00004664 True 933 mRNA 0.52 8 1109803 1180314

Neighbor


gene id symbol gene type direction distance location
XLOC_002494 glis3 coding downstream 392791 644574 ~ 690170 (-)
XLOC_002495 NA coding downstream 425555 657051 ~ 657406 (-)
XLOC_002493 rfx3 coding downstream 441352 600164 ~ 641609 (-)
XLOC_002492 NA coding downstream 534760 546202 ~ 548201 (-)
XLOC_002491 NA coding downstream 661308 415997 ~ 421653 (-)
XLOC_002497 pdlim5b coding upstream 7339 1187653 ~ 1276046 (-)
XLOC_002498 opn4xa coding upstream 114149 1294463 ~ 1320114 (-)
XLOC_002499 NA coding upstream 242927 1423241 ~ 1433140 (-)
XLOC_002500 WDR70 coding upstream 254642 1434956 ~ 1523289 (-)
XLOC_002501 CABZ01066320.2 coding upstream 360949 1541263 ~ 1544095 (-)
XLOC_002489 NA non-coding downstream 724254 356555 ~ 358707 (-)
XLOC_002488 NA non-coding downstream 728304 354093 ~ 354657 (-)
XLOC_002502 CABZ01066320.1 non-coding upstream 363849 1544163 ~ 1552789 (-)
XLOC_002504 NA non-coding upstream 486028 1666342 ~ 1667630 (-)
XLOC_002505 NA non-coding upstream 488830 1669144 ~ 1718637 (-)

Expression



Co-expression Network