XLOC_002511 (tdgf1)


Basic Information

Item Value
gene id XLOC_002511
gene name tdgf1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 1955475 ~ 1961930 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004686
CTGTATTCTAAGTTTTTCACATGAGAAATAAACATCTTTAGTAAAGTCCCGCATTAGAAGCATCAAAAGTCGCTAATCGCTTCTCTGTGATACTGAACTGAGTCGATTCGCTTCAAACCGGTTTGACTGACGGAATATGAATGGGGACTCGTTTGCATTAGTGGGTGTGCGCGCATGCATGACTATGGGAGGGTTTACAGGTGTGAATGGGGGAGTCTGAGGCCCTCGAGATAAATAACAGACCCAAACACAGGCACAGATAGAAGTTCTGTGAGATGGAGATGTTCTAATGGTGTTTTTGGGATACGAAAACTTACCTCAATCGAGTTGTTTTGGAGTTTATTGGCCAGCGGAATGACGAGTCAACTGTTCGGGTTCTTGATGTTTGCTGTGATTATTTGTCAAGCTGTTTCACTCGAGTCAGGATGTGAGGGGTCAGAATGTGTGAAAGTTGGGGTTTCTGGAAAGCCAAAGCAATACGCTGAATTCTTGAATAAATTTAACGAAATGAACACGCAAACGCCGCAACGTCAACACCGCAACGCCGAGGCAGCGTTACCGTTCGTTGGACTGACCGGAGTTGCCAAACAAAGCCGTACCTGCTGCAAGAATGGGGGAACGTGCATTTTGGGAAGTTTCTGCGCCTGTCCGAAGTACTTCACCGGCAGGAGCTGTGAATACGATGAACGCCTCAGGGATTGTGGTGTTATTCCACATGGAGAATGGGTTCAGAAAGGATGTTCGTACTGCAGATGTGGATATGGACTTTTGCATTGCTTCCCACATGTTTTCAGCAAAGACTGTGATGACTCTCAGGAAGTTCGGTGGCACCGGTCGGGCTCCCTCAGAACACTGTCGTCTACAATTGTCATGTTCGCCCCTTTTATTTTACACCGCCTGCTGTAAATGAGTTTTcctaatgggatagttcacccaaacaaagAAAATGATCTCCCCTGTTGAACGcagaagaagatactttgaaaaatgctggcacttgacttccatagtaggggaAACATTACTATGGAAGTGAACCAGCATTTCTCTTTTGTGCCCAAGAGAAGGAAGCAGCTCTCAAATAGGTTTTAAACCgttgaaggatgagtaaatgtgttcattttcgtgtgaactatccctttaacaaacaGAAAGcggttttattttagatttttttctgtcTGACAGGTTCGGGCAGCATTTATTGGTGGCACTGAAATGTGTTTTTGCTTCCAGTGGAAGTCTAACTAGCTGTGTTAAGAGCTGTTTAGTGAAGGAACATGTATATAggatttatattgaaaatatattgtgtgtgtgtgtcagtgcgcCGCCGAGCCAAATGAATTCTGTCCTTTTCTATGTCTCTGCGTGAATTTATTGTACCAGAGAGAGTGCGCCGGCTGAAAGCAAAGCATTTTCATCGTCTGTATCTGCAAATAcacgtgttttattttaatacatgtcATCTTAACAGTGAGCTGTGGCTTTTGTTTTTAAGTTCTCGCTAGTCGAATGTCCTTATTTGTGCTCCACAACTTTCATTTGCCGTGCTTGTTAATGGAGAAGGAGTCAGATAATGCAGAGATAGCCTGTGATTTGTTGACCTTTCGGCTATTTTCTCTTATCTTATACAAACAAGTCGTCCATTTGGCCAATCAATCTGGGTGGCTGGAGCGACCGTCTTGACCTTCTTGATGTACTGTAACGCTCCGTATGATTGAGCGAATTAATTTGTCTCATCCAATTAAAACTCGCATCAAAAACCC
>TCONS_00004687
ATGACGAGTCAACTGTTCGGGTTCTTGATGTTTGCTGTGATTATTTGTCAAGCTGTTTCACTCGAGTCAGGATGTGAGGGGTCAGAATGTGTGAAAGTTGGGGTTTCTGGAAAGCCAAAGCAATACGCTGAATTCTTGAATAAATTTAACGAAATGAACACGCAAACGCCGCAACGTCAACACCGCAACGCCGAGGCAGCGTTACCGTTCGTTGGACTGACCGGAGTTGCCAAACAAAGCCGTACCTGCTGCAAGAATGGGGGAACGTGCATTTTGGGAAGTTTCTGCGCCTGTCCGAAGTACTTCACCGGCAGGAGCTGTGAATACGATGAACGCCTCAGGGATTGTGGTGTTATTCCACATGGAGAATGGGTTCAGAAAGGATGTTCGTACTGCAGATGTGGATATGGACTTTTGCATTGCTTCCCACATGTTTTCAGCAAAGACTGTGATGTTTTCAGCAAAGACTGTGATGACTCTCAGGAAGTTCGGTGGCACCGGTCGGGCTCCCTCAGAACACTGTCGTCTACAATTGTCATGTTCGCCCCTTTTATTTTACACCGCCTGCTGTAA

Function

symbol description
tdgf1 Predicted to enable activin receptor binding activity and nodal binding activity. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and regionalization. Located in external side of plasma membrane. Is expressed in several structures, including EVL; cardiovascular system; diencephalon; ectoderm; and mesoderm. Used to study neural tube defect. Human ortholog(s) of this gene implicated in colon cancer; congenital heart disease; and visceral heterotaxy. Orthologous to several human genes including TDGF1 (teratocarcinoma-derived growth factor 1).

GO:

id name namespace
GO:0001706 endoderm formation biological_process
GO:0001707 mesoderm formation biological_process
GO:0021537 telencephalon development biological_process
GO:0035775 pronephric glomerulus morphogenesis biological_process
GO:0007498 mesoderm development biological_process
GO:0090008 hypoblast development biological_process
GO:0007507 heart development biological_process
GO:0001756 somitogenesis biological_process
GO:0038092 nodal signaling pathway biological_process
GO:0050930 induction of positive chemotaxis biological_process
GO:0021854 hypothalamus development biological_process
GO:0048565 digestive tract development biological_process
GO:0046619 optic placode formation involved in camera-type eye formation biological_process
GO:0048570 notochord morphogenesis biological_process
GO:0048854 brain morphogenesis biological_process
GO:0060975 cardioblast migration to the midline involved in heart field formation biological_process
GO:0048856 anatomical structure development biological_process
GO:0033504 floor plate development biological_process
GO:0001843 neural tube closure biological_process
GO:0001568 blood vessel development biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0048339 paraxial mesoderm development biological_process
GO:0061053 somite development biological_process
GO:0007398 ectoderm development biological_process
GO:0007417 central nervous system development biological_process
GO:0048382 mesendoderm development biological_process
GO:0060027 convergent extension involved in gastrulation biological_process
GO:0021999 neural plate anterior/posterior regionalization biological_process
GO:0030325 adrenal gland development biological_process
GO:0008354 germ cell migration biological_process
GO:0030900 forebrain development biological_process
GO:0030903 notochord development biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0072045 convergent extension involved in nephron morphogenesis biological_process
GO:0021501 prechordal plate formation biological_process
GO:0021508 floor plate formation biological_process
GO:0009897 external side of plasma membrane cellular_component
GO:0005576 extracellular region cellular_component
GO:0009986 cell surface cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0038100 nodal binding molecular_function
GO:0070697 activin receptor binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990415-198 Predicted to enable activin receptor binding activity and nodal binding activity. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and regionalization. Located in external side of plasma membrane. Is expressed in several structures, including EVL; cardiovascular system; diencephalon; ectoderm; and mesoderm. Used to study neural tube defect. Human ortholog(s) of this gene implicated in colon cancer; congenital heart disease; and visceral heterotaxy. Orthologous to several human genes including TDGF1 (teratocarcinoma-derived growth factor 1).

Ensembl:

ensembl_id ENSDARG00000035095

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004686 False 1769 mRNA 0.43 6 1955475 1961930
TCONS_00004687 True 573 mRNA 0.48 7 1956338 1961576

Neighbor

gene id symbol gene type direction distance location
XLOC_002510 NA coding downstream 2016 1948097 ~ 1953459 (-)
XLOC_002509 epb41l4a coding downstream 128250 1745475 ~ 1827225 (-)
XLOC_002506 NA coding downstream 214300 1678283 ~ 1741175 (-)
XLOC_002508 gal3st1b coding downstream 221538 1722125 ~ 1733937 (-)
XLOC_002505 NA coding downstream 236838 1669144 ~ 1718637 (-)
XLOC_002512 CU856539.1 coding upstream 537453 2499383 ~ 2527342 (-)
XLOC_002513 CU856539.3 coding upstream 611231 2573161 ~ 2603801 (-)
XLOC_002514 pdxp coding upstream 718149 2680079 ~ 2682198 (-)
XLOC_002515 mier3a coding upstream 733534 2695464 ~ 2713240 (-)
XLOC_002516 ash2l coding upstream 797296 2759226 ~ 2788792 (-)
XLOC_002504 NA non-coding downstream 287845 1666342 ~ 1667630 (-)
XLOC_002502 CABZ01066320.1 non-coding downstream 402686 1544163 ~ 1552789 (-)
XLOC_002518 NA non-coding upstream 936049 2897979 ~ 2899304 (-)
XLOC_002525 NA non-coding upstream 1360207 3322137 ~ 3332362 (-)
XLOC_002529 CU571170.1 non-coding upstream 1544610 3506540 ~ 3506654 (-)
XLOC_002530 FP236598.1 non-coding upstream 1806721 3768651 ~ 3768766 (-)
XLOC_002531 NA non-coding upstream 1992160 3954090 ~ 3956849 (-)

Expression


Co-expression Network