XLOC_025204 (hcrt)



Basic Information


Item Value
gene id XLOC_025204
gene name hcrt
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 17537352 ~ 17541448 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00049770
ATCAAGACTTTTCGATACATGACATTTGTCTACAAGACAGGGGACAGAAGCTAAACTCATGGACTGCACAGCTAAGAAGCTCCAGGTGCTCGTCTTCATGGCGCTGCTCGCTCACCTGGCCCGGGACGTGGAGGGCGTGGCCTCCTGCTGCGCGCGCGCTCCCGGCTCCTGCAAACTCTACGAGATGCTGTGCCGAGCAGGACGCAGAAACGACTCTTCCGTCGCCAGACATTTAGTGCATCTCAACAACGACGCCGCTGTCGGGATTCTCACTCTTGGCAAACGTAAAGTGGGCGAAAGCCGCGTCCACGACCGCCTGCAACAACTGCTGCACAACTCGCGGAATCAAGCCGCGGGGATCCTCACCATGGGGAAGAGGCTGGAGGAGCCCGCTAAATTCCTCATCCCTACGGTACCACAGGATGTGGACAGTTATGAAAAACGATGACACTTGTcgctatttaataataaaaacagaaaaaa

Function


symbol description
hcrt Predicted to enable neuropeptide hormone activity; type 1 hypocretin receptor binding activity; and type 2 hypocretin receptor binding activity. Acts upstream of or within several processes, including circadian sleep/wake cycle, wakefulness; multicellular organismal response to stress; and sleep. Predicted to be located in endoplasmic reticulum. Predicted to be active in perinuclear region of cytoplasm. Is expressed in brain; female organism; hypocretin-secreting neurons; male organism; and spinal cord. Human ortholog(s) of this gene implicated in narcolepsy. Orthologous to human HCRT (hypocretin neuropeptide precursor).

GO:

id name namespace
GO:0051971 positive regulation of transmission of nerve impulse biological_process
GO:0007218 neuropeptide signaling pathway biological_process
GO:0030431 sleep biological_process
GO:0042746 circadian sleep/wake cycle, wakefulness biological_process
GO:0042755 eating behavior biological_process
GO:0046928 regulation of neurotransmitter secretion biological_process
GO:0007631 feeding behavior biological_process
GO:0042594 response to starvation biological_process
GO:0033555 multicellular organismal response to stress biological_process
GO:0001659 temperature homeostasis biological_process
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0031771 type 1 hypocretin receptor binding molecular_function
GO:0031772 type 2 hypocretin receptor binding molecular_function
GO:0005184 neuropeptide hormone activity molecular_function
GO:0042324 hypocretin receptor binding molecular_function

KEGG:

id description
ko04080 Neuroactive ligand-receptor interaction

ZFIN:

id description
ZDB-GENE-040324-1 Predicted to enable neuropeptide hormone activity; type 1 hypocretin receptor binding activity; and type 2 hypocretin receptor binding activity. Acts upstream of or within several processes, including circadian sleep/wake cycle, wakefulness; multicellular organismal response to stress; and sleep. Predicted to be located in endoplasmic reticulum. Predicted to be active in perinuclear region of cytoplasm. Is expressed in brain; female organism; hypocretin-secreting neurons; male organism; and spinal cord. Human ortholog(s) of this gene implicated in narcolepsy. Orthologous to human HCRT (hypocretin neuropeptide precursor).

Ensembl:

ensembl_id ENSDARG00000070932

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00049770 True 483 mRNA 0.54 2 17537352 17541448

Neighbor


gene id symbol gene type direction distance location
XLOC_025202 si:ch211-210g13.5 coding upstream 14270 17346502 ~ 17523082 (+)
XLOC_025203 CU207238.1 coding upstream 75467 17395239 ~ 17461885 (+)
XLOC_025201 stat5a coding upstream 205433 17251542 ~ 17331919 (+)
XLOC_025200 stat3 coding upstream 429907 17030665 ~ 17107445 (+)
XLOC_025199 cavin1a coding upstream 525012 16976095 ~ 17012340 (+)
XLOC_025205 kcnh4a coding downstream 6084 17547532 ~ 17604109 (+)
XLOC_025206 rab5c coding downstream 74151 17615599 ~ 17651899 (+)
XLOC_025207 kat2a coding downstream 112336 17653784 ~ 17680114 (+)
XLOC_025208 dhx58 coding downstream 147971 17689419 ~ 17710221 (+)
XLOC_025209 znf385c coding downstream 202891 17744339 ~ 17860047 (+)
XLOC_025429 BX649540.1 misc downstream 12707291 30248739 ~ 30249036 (+)
XLOC_025197 BX470185.1 non-coding upstream 654048 16874401 ~ 16883304 (+)
XLOC_025188 CR388224.1 non-coding upstream 1164225 16373012 ~ 16373127 (+)
XLOC_025185 NA non-coding upstream 1296012 16186593 ~ 16241340 (+)
XLOC_025184 NA non-coding upstream 1375893 16153224 ~ 16161459 (+)
XLOC_025215 NA non-coding downstream 499165 18040613 ~ 18061783 (+)
XLOC_025218 NA non-coding downstream 648161 18189609 ~ 18197126 (+)
XLOC_025227 NA non-coding downstream 1129376 18670824 ~ 18672291 (+)
XLOC_025229 AL772362.2 non-coding downstream 1230080 18771528 ~ 18788485 (+)
XLOC_025233 AL772362.1 non-coding downstream 1326387 18867835 ~ 18867952 (+)

Expression



Co-expression Network