XLOC_025252 (tlk2)


Basic Information

Item Value
gene id XLOC_025252
gene name tlk2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 19685873 ~ 19717934 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00049865
GAACCGAACCGAATCGATTCTGATTTCGCCAATCTGATTGGAAAAGGGATTCTTTTCGTCTGTGTCGTCTAAGCTCTCTAAAAGGACATATCAGGGTGGAACGGTATTTAAAGAGCCGATTTATCATTTCAGGACGCGTGATCCAGGTTCGGTGCTGACCCGGAGCAGCGAAGACAAACAAGGGACAAAATATCTCATAGCCTCGCCGCTAACAACTAATTTCAAAGCGAATCGCGTGGTTTTGGGCAGGGATTTATTAAGCGTGGATCTACATAGCGATACCGCATGCTTCACATCTAGTAGAAAATAGATATCGGAAAAAGGCCAGCGGAGAAAGGCGGGTTCGGGATATCAAGGCCTCGGAGGTCCTTCAGTCCTCGGACTACAGTAGGGCGCGGAGCTGGCGTCCCCCAGCGACACAGCAGTCACCAAGCGCTGGCGAGGGTCGGGGATTTGGCTGTGGCCTAGCGCTGAGATGTCTGGCTGAGACGGAAAGGGCGAGACGGGAGACCCGAGGAGGAGAACGGTCGAAGAAAAGACATCCAATAAAACGGAAAGCGGGAGAAAAGACTCCATCAATACAGCCATGATGGAGGAATTGCACAGCTTGGATCCTCGAAGGCAAGAGCTGCTGGAGGCCCGTTTCACAGGAGTCGGAGTTGCCAAGGGATCTGGACACAACGAGTCCTCCAACCAGAGCTTGTGTAGTGTGGGCTCTCTCAGTGACAAAGAATTGGAGACCCCAGAGAAGAAATCTAATGACCAGAGGACACGTAAAAGGAAAGGAGACCCCTTTGACAGCCAGGgcaaaggaggaggaagaggacacAAAATTAGTGATTATTTTGAGtttgcagGCGGTAGTGGTACAGGTACCAGTCCAGCTCGTGGCATTCCTCCAGTGGCGCGCTCCTCTCCTCAGCACTCTCTATCTAATCCTCCTGCTGCCgtgcagcAAGGAAGCCCCTCCTCCATCAGTTCAGTAAACACAGACCACTCCCACACCTCCACCTCCCACAAGCCAGCCTCAATACACACTCAGCACCGAGCTTCACAGTCTGAGCTGACTATGGAGAAATTAGCAGCGCTGGAGAGCAGTAAGAGTTCAGATCTGGAGAAGAAAGAAGGACGTATCGATGACCTGCTCAGGGTGAACTGTGACCTGCGCAGACAGATCGATGAGCAGCAGAAGATGCTGGAGTGGTGTAAAGAACGCCTCAATAAATGTGTGACCATGAGTAAGAAACTGCTTATCGAAAAGtccAAACAGGAGAAAATTGCTTGCAGAGAAAAGAGCATGCAGGACCGACTACGACTTGGTCATTTCACCACTGTACGACACGGAGCCTCATTTACAGAGCAGTGGACGGATGGATATGCGTTTCAGAATCTAGTCAAacaacAGGAGAGAGTCAACGGGCAGAGGGAGGAAATAGAGAGACAGAGAAAACTGCTAATAAAAAAGAAACCACCCAGCGCCAGTCAGACTCCTCCTCCTAATCTAGAACCCAACAAACGCAAAAGCAAGAGCAACGGCGCCGAGAATGAAATGTTGTCTCTAGCAGAGTACCACGAGCAAGAAGAAATTTTCAAACTGAGACTTGGCCACCTAAAGAAGGAGGAAGCCGAGATCCAGGTGGAACTGGAGCGGTTGGAGCGTGTGCGTAATCTTCACATCCGCGAGCTCAAGAGAATCCACAATGAAGATAACTCCCAGTTTAAAGATCATCCTACGCTAAATGACCGTTACCTGCTCTTGCATCTGCTCGGACGAGGAGGCTTCAGTGAGGTCTACAAGGCCTTCGACTTAACTGAGCAGAGGTACGTGGCTGTGAAGATTCACCAGCTTAATAAGAACTGGAGAGACGAGAAGAAAGAAAACTACCACAAGCATGCCTGTCGAGAATATAGAATCCATAAAGAGCTGGACCATCCCAGAATAGTCAAACTGTATGACTACTTTTCCCTGGATACTGACTCATTCTGCACTGTTCTGGAGTACTGCGAGGGAAACGATCTGGATTTCTACCTGAAGCAGCACAAGTTAATGTCAGAAAAAGAGGCCCGGTCCATCATAATGCAGGTCGTCAATGCCCTCAAGTACCTAAATGAAATCCGCCCGCCGATCATCCATTACGACCTCAAACCAGGTAACATCCTGCTGGTGAATGGCACAGCATGTGGAGAGATAAAGATCACAGACTTTGGGCTGTCCAAGATCATGGATGATGACAACTATGGCGTGGATGGCATGGAGTTGACGTCACAAGGGGCAGGGACATACTGGTATCTTCCTCCAGAGTGCTTTGTGGTTGGAAAAGAGCCACCTAAGATCTCCAACAAAGTGGATGTTTGGTCAGTTGGAGTTATCTTTTACCAGTGCCTCTATGGaaagaagCCGTTCGGTCATAATCAGTCCCAGCAGGACATCCTTCAGGAGAACACTATTCTCAAAGCCACAGAGGTGCAGTTTCCTCCCAAACCAGGAGTCTCGCCTGAGGCTAAGGCCTTCATCCGCAGATGTCTGGTGTACCGTAAGGAGGACCGTATTGATGTTCACCAGCTGGCCAGTGACCCCTACCTCCTCCCGCACATACGCAAGTCCGTGGCGGCCACGGGTAACTCCAGCATGGCCGTGGCCTCCACCTCCAACTCCTCCAACAGCAGCGCCTCAAACTGAGAGCCCCGCCCATCCTTGCTTGTTCTGATTGGAGCAGAGCGCGTGAGGTGTTTTGCCCCACCCCTCTCTGCAGTGCATCGGAAGGGGGTCGAACCCCTTACCTGCCAACTGAGGGAGCAGGAGGAACTGGGTAAGAGAGGGATGGAGATAAGACGCATCCCCCTCCACCCTTCTTCCTCTCCCAGGCATCTGGaaggtttttatttcttttatttctcatTCTCGGATGGAAGGGGACTAAAGGCGCCCCGCATCGAGTGAGCCAGAGGGATTCAATATAAGGCTGTATTATCTGTGAGAAGGACCGAAGTGCAGCAGCTCAGACTGGAGGAAGAGACTGGTATATGCCCTGCAccccacacatgcacacacacacacacacacacacatttataatgaGGCCAGCTTGATTTTTCTTACAGTAATGGGACGAGTCCATTTATACTAATGTGCATTCAAGTGTACAATATTCCTAAAGAATCTTTAGATGACACAAAGCCCGTCCCGGTTTTCCTTCCTTGCTCgctcttatttttattattattattatattttccacCTCTGGAATGGATCTATGAACTTTTGGAAGCAATACTGTCAATGGGGTTCTTTTCAGTGATTTCAATGGAGTTTTAAACCCTAGTTTTAAATGCCTTTCTGAACTGCCATCAGatcatttaataaatgcagcagGACCTGTAGGTTAGCTGATCTTCAGTGCTGGGATTCAGATGTTTGCTCTGGAGCCCCAAATGTTTGTCTGTTTATGTCCTGCTCACTTCCGCCCCTGTTTAATGACCAAAGCTGAGCTCCACCAATAGGTGGTGCTGTTTGACttgagtgtttctttttttttttgttttttttttttgctgtaattaaaatgttttttgttttttagcaaGCTTATTCTTTGTAGATTTAGCGACACTAACCCATGCCCCTTCCTTGCCCCAAGTCTGTTCTTGTTTCTTATTGTGTCTTTGGACAGAATCTAATGCTGAAAAATGAGATGATGAGATTTTATTTTTCATCGAATTTAAAAGTGTTGTGCCTCACCTAGAAACACAGACACCAATGCGTTCAGAAATCACACACAGTCATATATGTTTAGGTCTGGTGATACGGCTGATTTGCCTGATCCTGTTTTACTGTTTGTGGGGAAGGAAGGAACTCTCTCTAGGGGGCGGAGATAGTGCAGGGGTACAGGGCAGAGTGCGGAGCGACCATTAAATGCTATTGGTTATTAA
>TCONS_00049866
GGCTGAGTCATGAATGTCAGAATGCTCTCGAAAAAAACATGTATTGGGGACACATGACTCAACATGTCACACACATTACTGTCCCGTCAATCTGTCAGTATCACTATGGCTACATAATGCTATGCACACTCTCTTCCTCTCTTCTCAGCCATGATGGAGGAATTGCACAGCTTGGATCCTCGAAGGCAAGAGCTGCTGGAGGCCCGTTTCACAGGAGTCGGAGTTGCCAAGGGATCTGGACACAACGAGTCCTCCAACCAGAGCTTGTGTAGTGTGGGCTCTCTCAGTGACAAAGAATTGGAGACCCCAGAGAAGAAATCTAATGACCAGAGGACACGTAAAAGGAAAGGAGACCCCTTTGACAGCCAGGgcaaaggaggaggaagaggacacAAAATTAGTGATTATTTTGAGtttgcagGCGGTAGTGGTACAGGTACCAGTCCAGCTCGTGGCATTCCTCCAGTGGCGCGCTCCTCTCCTCAGCACTCTCTATCTAATCCTCCTGCTGCCgtgcagcAAGGAAGCCCCTCCTCCATCAGTTCAGTAAACACAGACCACTCCCACACCTCCACCTCCCACAAGCCAGCCTCAATACACACTCAGCACCGAGCTTCACAGTCTGAGCTGACTATGGAGAAATTAGCAGCGCTGGAGAGCAGTAAGAGTTCAGATCTGGAGAAGAAAGAAGGACGTATCGATGACCTGCTCAGGGTGAACTGTGACCTGCGCAGACAGATCGATGAGCAGCAGAAGATGCTGGAGTGGTGTAAAGAACGCCTCAATAAATGTGTGACCATGAGTAAGAAACTGCTTATCGAAAAGtccAAACAGGAGAAAATTGCTTGCAGAGAAAAGAGCATGCAGGACCGACTACGACTTGGTCATTTCACCACTGTACGACACGGAGCCTCATTTACAGAGCAGTGGACGGATGGATATGCGTTTCAGAATCTAGTCAAacaacAGGAGAGAGTCAACGGGCAGAGGGAGGAAATAGAGAGACAGAGAAAACTGCTAATAAAAAAGAAACCACCCAGCGCCAGTCAGACTCCTCCTCCTAATCTAGAACCCAACAAACGCAAAAGCAAGAGCAACGGCGCCGAGAATGAAATGTTGTCTCTAGCAGAGTACCACGAGCAAGAAGAAATTTTCAAACTGAGACTTGGCCACCTAAAGAAGGAGGAAGCCGAGATCCAGGTGGAACTGGAGCGGTTGGAGCGTGTGCGTAATCTTCACATCCGCGAGCTCAAGAGAATCCACAATGAAGATAACTCCCAGTTTAAAGATCATCCTACGCTAAATGACCGTTACCTGCTCTTGCATCTGCTCGGACGAGGAGGCTTCAGTGAGGTCTACAAGGCCTTCGACTTAACTGAGCAGAGGTACGTGGCTGTGAAGATTCACCAGCTTAATAAGAACTGGAGAGACGAGAAGAAAGAAAACTACCACAAGCATGCCTGTCGAGAATATAGAATCCATAAAGAGCTGGACCATCCCAGAATAGTCAAACTGTATGACTACTTTTCCCTGGATACTGACTCATTCTGCACTGTTCTGGAGTACTGCGAGGGAAACGATCTGGATTTCTACCTGAAGCAGCACAAGTTAATGTCAGAAAAAGAGGCCCGGTCCATCATAATGCAGGTCGTCAATGCCCTCAAGTACCTAAATGAAATCCGCCCGCCGATCATCCATTACGACCTCAAACCAGGTAACATCCTGCTGGTGAATGGCACAGCATGTGGAGAGATAAAGATCACAGACTTTGGGCTGTCCAAGATCATGGATGATGACAACTATGGCGTGGATGGCATGGAGTTGACGTCACAAGGGGCAGGGACATACTGGTATCTTCCTCCAGAGTGCTTTGTGGTTGGAAAAGAGCCACCTAAGATCTCCAACAAAGTGGATGTTTGGTCAGTTGGAGTTATCTTTTACCAGTGCCTCTATGGaaagaagCCGTTCGGTCATAATCAGTCCCAGCAGGACATCCTTCAGGAGAACACTATTCTCAAAGCCACAGAGGTGCAGTTTCCTCCCAAACCAGGAGTCTCGCCTGAGGCTAAGGCCTTCATCCGCAGATGTCTGGTGTACCGTAAGGAGGACCGTATTGATGTTCACCAGCTGGCCAGTGACCCCTACCTCCTCCCGCACATACGCAAGTCCGTGGCGGCCACGGGTAACTCCAGCATGGCCGTGGCCTCCACCTCCAACTCCTCCAACAGCAGCGCCTCAAACTGAGAGCCCCGCCCATCCTTGCTTGTTCTGATTGGAGCAGAGCGCGTGAGGTGTTTTGCCCCACCCCTCTCTGCAGTGCATCGGAAGGGGGTCGAACCCCTTACCTGCCAACTGAGGGAGCAGGAGGAACTGGGTAAGAGAGGGATGGAGATAAGACGCATCCCCCTCCACCCTTCTTCCTCTCCCAGGCATCTGGaaggtttttatttcttttatttctcatTCTCGGATGGAAGGGGACTAAAGGCGCCCCGCATCGAGTGAGCCAGAGGGATTCAATATAAGGCTGTATTATCTGTGAGAAGGACCGAAGTGCAGCAGCTCAGACTGGAGGAAGAGACTGGTATATGCCCTGCAccccacacatgcacacacacacacacacacacacatttataatgaGGCCAGCTTGATTTTTCTTACAGTAATGGGACGAGTCCATTTATACTAATGTGCATTCAAGTGTACAATATTCCTAAAGAATCTTTAGATGACACAAAGCCCGTCCCGGTTTTCCTTCCTTGCTCgctcttatttttattattattattatattttccacCTCTGGAATGGATCTATGAACTTTTGGAAGCAATACTGTCAATGGGGTTCTTTTCAGTGATTTCAATGGAGTTTTAAACCCTAGTTTTAAATGCCTTTCTGAACTGCCATCAGatcatttaataaatgcagcagGACCTGTAGGTTAGCTGATCTTCAGTGCTGGGATTCAGATGTTTGCTCTGGAGCCCCAAATGTTTGTCTGTTTATGTCCTGCTCACTTCCGCCCCTGTTTAATGACCAAAGCTGAGCTCCACCAATAGGTGGTGCTGTTTGACttgagtgtttctttttttttttgttttttttttttgctgtaattaaaatgttttttgttttttagcaaGCTTATTCTTTGTAGATTTAGCGACACTAACCCATGCCCCTTCCTTGCCCCAAGTCTGTTCTTGTTTCTTATTGTGTCTTTGGACAGAATCTAATGCTGAAAAATGAGATGATGAGATTTTATTTTTCATCGAATTTAAAAGTGTTGTGCCTCACCTAGAAACACAGACACCAATGCGTTCAGAAATCACACACAGTCATATATGTTTAGGTCTGGTGATACGGCTGATTTGCCTGATCCTGTTTTACTGTTTGTGGGGAAGGAAGGAACTCTCTCTAGGGGGCGGAGATAGTGCAGGGGTACAGGGCAGAGTGCGGAGCGACCATTAAATGCTATTGGTTATTAATA

Function

symbol description
tlk2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including intracellular signal transduction; peptidyl-serine phosphorylation; and regulation of chromatin assembly or disassembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human TLK2 (tousled like kinase 2).

GO:

id name namespace
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0006468 protein phosphorylation biological_process
GO:0007059 chromosome segregation biological_process
GO:0016310 phosphorylation biological_process
GO:0001672 regulation of chromatin assembly or disassembly biological_process
GO:0005634 nucleus cellular_component
GO:0016740 transferase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0016301 kinase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060623-36 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including intracellular signal transduction; peptidyl-serine phosphorylation; and regulation of chromatin assembly or disassembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human TLK2 (tousled like kinase 2).

Ensembl:

ensembl_id ENSDARG00000010779

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00049865 False 3930 mRNA 0.48 21 19685873 19717932
TCONS_00049866 True 3496 mRNA 0.47 20 19687217 19717934

Neighbor

gene id symbol gene type direction distance location
XLOC_025251 mettl2a coding upstream 3054 19665319 ~ 19682819 (+)
XLOC_025250 itgb3a coding upstream 36338 19621034 ~ 19649535 (+)
XLOC_025249 rprml coding upstream 74883 19609638 ~ 19610990 (+)
XLOC_025247 CU571315.1 coding upstream 208400 19468777 ~ 19477473 (+)
XLOC_025248 NA coding upstream 212676 19472963 ~ 19473197 (+)
XLOC_025253 mrc2 coding downstream 14239 19732173 ~ 19813526 (+)
XLOC_025254 vat1 coding downstream 196398 19914332 ~ 19971774 (+)
XLOC_025255 asb16 coding downstream 283674 20001608 ~ 20011807 (+)
XLOC_025256 tmub2 coding downstream 294957 20012891 ~ 20021596 (+)
XLOC_025257 NA coding downstream 341744 20059678 ~ 20064732 (+)
XLOC_025429 BX649540.1 misc downstream 10530805 30248739 ~ 30249036 (+)
XLOC_025243 BX322663.1 non-coding upstream 336056 19349719 ~ 19349817 (+)
XLOC_025241 BX322663.3 non-coding upstream 372766 19312991 ~ 19313107 (+)
XLOC_025235 CU151886.1 non-coding upstream 768290 18917461 ~ 18917583 (+)
XLOC_025234 CU151886.2 non-coding upstream 793107 18892650 ~ 18892766 (+)
XLOC_025259 NA non-coding downstream 480368 20198302 ~ 20198619 (+)
XLOC_025261 NA non-coding downstream 773268 20491202 ~ 20509513 (+)
XLOC_025262 BX248239.1 non-coding downstream 961989 20679923 ~ 20680038 (+)
XLOC_025263 BX936284.1 non-coding downstream 1195376 20913310 ~ 20915154 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000034_04065210_04081772 TLK2 coding CI01000034 null 4064519 ~ 4081772 (-)
bowfin (Amia calva) AMCG00001015 tlk1 coding CM030137.1 CM030137.1 12094466 ~ 12110600 (-)