XLOC_025294 (col1a1a)



Basic Information


Item Value
gene id XLOC_025294
gene name col1a1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 23221047 ~ 23239458 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00049937
AGTAGGGAGTTTCTGCTGGGGTCTGGATTGGAGTCACAGAAGACCGGACCCTACCGTGTATGATTGGAGTCTAAAGGAAAACAGAACTTCCCTCGCCTCAAAGAGTCTACATGTCTAATATTTAGACATGTTCAGCTTTGTGGATATTCGGCTGGCGCTGTTGCTCAGCGCAACGGTGCTTTTGGCAAGAGGACAAGGCGAGGACGATCGCACTGGCGGCAGCTGCACATTGGACGGCCAGGTCTACAATGACAGGGACGTCTGGAAACCAGAGCCATGCCAAATCTGCGTGTGCGACAGCGGCACCGTAATGTGCGACGAAGTGATCTGCGAGGACACAAGCGACTGCCCCAACCCAGTGATTCCCCACGACGAGTGCTGCCCCGTCTGCCCAGACGACGATTTCCAGGAGCCCAGTGTTGAGGGACCTAGAGGTTCTCCCGGTGACAAGGGTGAGAGGGGTCCTGCTGGCCCTCCCGGCAATGATGGAATCCCTGGACAGCCTGGCCTCCCTGGGCCTCCAGGCCCTCCTGGACCTCCTGGCCTTGGTGGAAACTTTTCTCCTCAGATGTCTGGTGGCTTTGATGAGAAATCCTCTCCAATGGCTGTCCCAGGCCCCATGggaccTATGGGCCCCCGTGGAGCCCCTGGACCTCCTGGACCTTCCGGACCCCAAGGATTTACTGGTCCCCCTGGCGAGCCTGGTGAGGCTGGTGCTCCTGGTCCAATGGGTCCCCGTGGCGCTGCTGGTCCCCCTGGAAAGAATGGAGAGGATGGTGAGTCTGGCAAACCTGGTCGCCCTGGTGAGCGCGGACCCCCTGGACCACAGGGTGCTCGTGGATTCCCCGGAACCCCTGGACTTCCAGGCATCAAGGGACACAGAGGATTCAGCGGTCTAGATGGAGCTAAGGGGGATGCTGGCCCTGCTGGACCTAAGGGTGAGCCTGGTGCACCTGGTGAGAATGGAACTCCTGGTGCCATGGGTCCCCGTGGTCTGCCTGGCGAGAGAGGCCGTGCTGGTCCTCCTGGTGCTGCTGGTGCTCGTGGTAATGATGGTGCCGCTGGAGCTGCTGGTCCTCCTGGCCCAACTGGCCCTGCTGGTCCCCCAGGATTCCCTGGCGGCCCTGGATCTAAgGGAGAGGTTGGTCCTCAGGGATCCCGTGGTGCAGAGGGACCTCAGGGAGCCCGTGGTGAAGCTGGTAACCCTGGACCTGCTGGTCCTGCTGGTCCCGCTGGTAACAACGGAGCTGATGGTGCCCCTGGTGCCAAGGGTGCTCCTGGCGCTCCTGGTATTGCTGGTGCTCCTGGTTTCCCTGGACCCCGTGGTCCTCCTGGAGCTGCTGGAGCGGCTGGTGCCCCTGGCCCTAAGGGTAACACCGGTGAGGCTGGTGCCCCAGGTGCCAAAGGAGAGGCTGGTGCTAAGGGAGAGGCTGGTGCCCAAGGAGTTCAGGGTCCCCCTGGTCCCCCTGGTGAGGAAGGCAAGAGAGGACCCCGTGGTGAGCCCGGTGCTGGTGGTGCCCGCGGACCTACTGGTGAACGTGGTGCTCCTGGTGCTCGTGGTTTCCCTGGTGCTGATGGAGCTGCAGGTCCAAGAGGTGCCCCTGGTGAGCGTGGAGGCCCTGGAGTTGTTGGACCTAAGGGTGCCACTGGTGAGCCTGGCCGCAATGGTGAACCTGGTATGCCAGGATCCAAGGGTATGACTGGTAGCCCTGGCAGCCCTGGACCTGATGGAAAGACCGGACCTGGTGGTGCTCCTGGACAAGATGGCCGCCCTGGACCACCTGGCCCTGTTGGAGCCAGAGGACAGCCTGGTGTCATGGGATTCCCTGGACCTAAGGGTGCTGCTGGTGAGGCTGGCAAACCTGGTGAGAGAGGAGTGATGGGTGCTATTGGTGCCACTGGCGCTCCTGGTAAGGATGGTGATGTTGGTGCCCCTGGTGCTCCTGGACCTGCTGGACCTGCTGGTGAGAGAGGTGAACAAGGAGCTGCTGGTCCTCCTGGATTCCAGGGTCTGCCAGGACCTCAGGGTGCTACTGGTGAGCCAGGAAAGTCTGGTGAGCAGGGTGCTCCTGGAGAAGCTGGAGCTCCTGGACCTTCTGGTTCTAGAGGTGACAGAGGATTCCCTGGTGAGCGTGGTGCCCCTGGCCCTGCTGGCCCTGTTGGTGCCCGTGGTTCTCCTGGTTCAGCTGGTAACGATGGTGCCAAGGGTGAAAGTGGTGCCGCAGGTGCTCCTGGTGCCCAGGGTCCTCCTGGACTTCAAGGAATGCCTGGAGAGCGTGGGGCTGCTGGCCTCCCTGGTCTTAAGGGTGACAGAGGTGACCAAGGTGCCAAGGGTGCTGATGGTGCTGCTGGTAAAGATGGCATTCGTGGTATGACCGGACCAATTGGACCCCCCGGACCTGCTGGAGCTCCTGGTGACAAGGGAGAATCTGGTGCTCAAGGACTTGTTGGACCTACTGGTGCCCGTGGACCACCTGGTGAGCGTGGAGAGACTGGTGCTCCTGGACCTGCCGGATTTGCTGGACCTCCTGGTGCTGATGGTCTGCCTGGTGCCAAGGGAGAACCTGGAGATAATGGTGCTAAGGGTGATGCTGGTGCTCCAGGACCTGCAGGAGCAACTGGTGCCCCTGGACCTCAGGGTCCCGTTGGTGCTACTGGACCCAAGGGTGCCCGTGGTGCTGCTGGTCCTCCTggtGCTACTGGCTTCCCTGGTGCTGCTGGCAGAGTTGGACCTCCTGGCCCTTCTGGAAATTCTGGACCCCCAGGACCTCCTGGACCCGCTGGTAAGGAGGGCCAGAAAGGTAACCGTGGTGAGACTGGACCTGCTGGTCGTACTGGTGAAGTTGGTGCTGCTGGACCACCTGGTGCCCCTGGTGAGAAAGGAAATCCCGGAGCTGAGGGTGCCACTGGCCCTGCTGGTATCCCTGGACCTCAAGGTATTGGTGGTCAGCGTGGTATTGTAGGTCTCCCTGGACAAAGAGGCGAGCGTGGTTTCCCCGGTCTCCCTGGCCCATCTGGAGAGATTGGCAAACAGGGACCTTCTGGTCCATCTGGTGAACGTGGACCTCCTGGCCCCATGGGACCCCCTGGACTGGCTGGACCTCCTGGTGAGCCTGGTCGTGAGGGTACTCCAGGAAATGAGGGCTCTGCTGGACGTGACGGTGCTGCTGGCCCCAAGGGTGACCGTGGTGAGACTGGCCCATCTGGCACTCCTGGAGCCCCTGGACCTCCTGGTGCTGCTGGACCTATTGGCCCTGCTGGAAAGACTGGTGATCGTGGAGAGACCgGCCCTGCTGGTGTCCCCGGCCCTGCTGGCCCCTCTGGTCCCCGCGGACCCTCTGGACCCGCTGGAGCTCGTGGAGACAAGGGTGAGACTGGTGAGGCTGGTGAGAGAGGCATGAAGGGACACAGAGGATTCACTGGAATGCCAGGACCCCCTGGTCCTCCTGGACCCTCTGGAGAGTCTGGACCCGCTGGTGCTTCTGGACCCGCTGGACCAAGAGGCCCAGCTGGATCTGCTGGATCAGCTGGTAAGGATGGTATGAGTGGCCTCCCTGGACCCATTGGACCTCCTGGACCCCGTGGTCGCAATGGAGAAATTGGACCAGCTGGACCTCCTGGACCTCCCGGCCCCCCTGGAGCACCTGGACCCTCTGGTGGTGGATTCGACATTGGCTTCATTGCCCAGCCACAGGAGAAGGCCCCTGATCCCTTCCGTCACTTCCGTGCCGACGATGCCAATGTGATGCGCGACCGTGATCTTGAGGTTGACACCACCCTTAAGTCCCTGAGCCAGCAGATTGAGAGCATCATCAGCCCAGACGGCACCAAGAAGAACCCTGCCCGCACTTGCCGTGACCTGAAGATGTGCCACCCAGACTGGAAGAGCGGCGAGTACTGGATTGACCCTGACCAGGGCTGCAACCAGGATGCCATCAAGGTCTACTGCAACATGGAAACTGGCGAGACTTGCGTCAACCCAACTGAGTCTGCTATTCCCAAGAAGAACTGGTACACAAGCAAGAACATTAAGGAGAAGAAACACGTCTGGTTCGGAGAGGCCATGACCGATGGCTTCCAGTTCGAGTATGGCAGCGAGGGCTCCAAGCCTGAGGATGTCAACATTCAGCTCACCTTCCTGCGCCTCATGTCCACTGAGGCCTCCCAGAACATTACATACCACTGCAAGAACAGCATTGCATACATGGACCAGGCTTCTGGCAACCTGAAGAAGGCTCTTCTCCTGCAGGGCTCCAACGAAATTGAGATCAGAGCAGAGGGCAACAGCCGCTTCACATACAGTGTCACTGAGGATGGTTGCACGTCGCACACCGGTGCATGGGGCAAGACAGTCATTGACTACAAAACAACGAAAACATCCCGTCTGCCTATTATTGACATCGCCCCTATGGACGTTGGTGCACCTAATCAGGAATTTGGCATTGAAGTTGGCCCAGTCTGCTTCTTGTAAAAAAGAAATCTGGACTTGAgattgtttgtgtgcgtgtgtgtttttttctagcAATCATCTCTCTAAAATCTTTTCTATGCATTAAAATCAAACCCTAGAATCCAATTTGGCTGTCCAAATGGTCCACTTGCTTAGACCTGCGCTTCAGAAGACAGTGGTTGTGTGTTATCAGGCTTTTTTTGGACCACTATTTTGTCACCACCCACACTGAGGATACTTTAGAAGACTCATTTGTTTCACTGGCaacaagaaaataatatataCTTATAGCGTGTAAAATCCCCCTGGAGTTTTAAAGAAACATCAATGATACAAGTGACTTTTTTCAACCACTGAGGAAGGACAATGAAAGAGCGAAACCAAATGCTTTGTACCATGTTCaggtgttaaataaatctgtaaaatgacatTTAAGTGTCTCTGTGTTATACCCATTAGGACCACCGGGTGCCGAATGCCAACGTTCCTCTCAAGTCACACGAGTACATCTAGTAGAGACAGGGGTTCAactttgttttgatgttttatgGCTACCTCAAAAAAGAAACCTGCGATTCCCAGTGTTGACCAACACCAGGTCAGGATTTTACTTGGCAGAAGTATTGTTAAGAGAACAAGTGACAGCTGTAAAGGTGCTATTTCCTCATGAGGTCCTGTTAGCAAGAAATCAAGGAGTTTCACAAAATGTATTGTTCGTCGCTTTTGCTCACAGGGCCTTTGGTGCTAAGGAACCCCAGCATCTTGCTGCCCAGTTGTAACAGATGCTTCCCTTTCTGAAGTGAAGAGCCAGACAGCAGAGCTTTTGTTAAAAAGCAGTACTGTAGCTGTGATGCATGCAGTCTTTTCAAGTGTAGAATAAGCAGGTGGAGTCTGTTTTTATTTTCCAAACGCCTTTTGACACTTTTTGGTTGTTGTCTTTTGGTTTCTTTATAAAATATCCCCCCACAAATGTCGTTCAGTTGCTTCCAGCTATTCCCCCTACTTCCCTCCCATCCTTCTGTAATCTGGATTTGTTTTGTTCTCAccctggtttttttttttaagcgtaaAACAGACAATCAAATAGAAAAGTCCTAAAATCATGAGAGAAGCACACCTTAGGGGGGTAAAAACAAGAAGATCTGTACCTATTTTGTATATGTATAATAATTTgagatgtttttaattattttgaatgcTGAAATAAAGCATGTTAAGTGGTCGACCTATGTTTGTCAGAAGTGATCTTGACTCGTCCCTGACTGCCCAATGGACTTGAATGAAGCACAGCTTGCACCTGTTACAGTTGTTTTGACTAAAAGGAAAGATTAAAGAAAATCTCAGAAA
>TCONS_00049938
ATTAAGGAGAAGAAACACGTCTGGTTCGGAGAGGCCATGACCGATGGCTTCCAGTTCGAGTATGGCAGCGAGGGCTCCAAGCCTGAGGATGTCAACATTCAGCTCACCTTCCTGCGCCTCATGTCCACTGAGGCCTCCCAGAACATTACATACCACTGCAAGAACAGCATTGCATACATGGACCAGGCTTCTGGCAACCTGAAGAAGGCTCTTCTCCTGCAGGGCTCCAACGAAATTGAGATCAGAGCAGAGGGCAACAGCCGCTTCACATACAGTGTCACTGAGGATGGTTGCACGTCGCACACCGGTGCATGGGGCAAGACAGTCATTGACTACAAAACAACGAAAACATCCCGTCTGCCTATTATTGACATCGCCCCTATGGACGTTGGTGCACCTAATCAGGAATTTGGCATTGAAGTTGGCCCAGTCTGCTTCTTGTAAAAAAGAAATCTGGACTTGAgattgtttgtgaaaaaataaagatCTAAACCACCAGAGggcgagtaaataGAAAGTaaagagaattgacaggaaagcatggggagcagagagaggggaaggatcggcataggaccacgAGGctgaatcgaactcgggtcgccgtgagcaccggagtgccgacgcactaaccactacaccactgtcGCTGACGTATATACAGTATGCAACTTATTAAACAACACATATTTATGCG

Function


symbol description
col1a1a Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including bone mineralization involved in bone maturation; fin development; and fin regeneration. Located in cytoplasm. Is expressed in several structures, including head; integument; myotome; pectoral fin; and vertebra. Used to study osteogenesis imperfecta and osteogenesis imperfecta type 3. Human ortholog(s) of this gene implicated in several diseases, including Ehlers-Danlos syndrome arthrochalasia type 1; aggressive periodontitis; bone disease (multiple); cutaneous leishmaniasis; and dentinogenesis imperfecta. Orthologous to human COL1A1 (collagen type I alpha 1 chain).

GO:

id name namespace
GO:0046849 bone remodeling biological_process
GO:0001501 skeletal system development biological_process
GO:0030198 extracellular matrix organization biological_process
GO:0035630 bone mineralization involved in bone maturation biological_process
GO:0031101 fin regeneration biological_process
GO:0030278 regulation of ossification biological_process
GO:0033333 fin development biological_process
GO:0033334 fin morphogenesis biological_process
GO:0033339 pectoral fin development biological_process
GO:0031012 extracellular matrix cellular_component
GO:0005581 collagen trimer cellular_component
GO:0005615 extracellular space cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005201 extracellular matrix structural constituent molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-9102 Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including bone mineralization involved in bone maturation; fin development; and fin regeneration. Located in cytoplasm. Is expressed in several structures, including head; integument; myotome; pectoral fin; and vertebra. Used to study osteogenesis imperfecta and osteogenesis imperfecta type 3. Human ortholog(s) of this gene implicated in several diseases, including Ehlers-Danlos syndrome arthrochalasia type 1; aggressive periodontitis; bone disease (multiple); cutaneous leishmaniasis; and dentinogenesis imperfecta. Orthologous to human COL1A1 (collagen type I alpha 1 chain).

Ensembl:

ensembl_id ENSDARG00000012405

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00049937 False 5797 mRNA 0.56 51 23221047 23237816
TCONS_00049938 True 697 processed_transcript 0.49 5 23235668 23239458

Neighbor


gene id symbol gene type direction distance location
XLOC_025293 NA coding upstream 7718 23096442 ~ 23213329 (+)
XLOC_025292 gngt2a coding upstream 124906 23092762 ~ 23096141 (+)
XLOC_025291 b4galnt2.1 coding upstream 135768 23063718 ~ 23085279 (+)
XLOC_025290 nags coding upstream 160926 23029484 ~ 23060121 (+)
XLOC_025289 si:ch211-237i5.4 coding upstream 200496 22999849 ~ 23020551 (+)
XLOC_025295 ppp1r9ba coding downstream 7867 23247325 ~ 23348084 (+)
XLOC_025296 NA coding downstream 167013 23406471 ~ 23411521 (+)
XLOC_025297 nr1d1 coding downstream 249194 23488652 ~ 23496223 (+)
XLOC_025298 NA coding downstream 278501 23517959 ~ 23524650 (+)
XLOC_025299 NA coding downstream 365020 23604478 ~ 23616801 (+)
XLOC_025429 BX649540.1 misc downstream 7009281 30248739 ~ 30249036 (+)
XLOC_025286 BX322574.1 non-coding upstream 340600 22854673 ~ 22880447 (+)
XLOC_025285 NA non-coding upstream 372851 22846336 ~ 22848196 (+)
XLOC_025283 BX649557.1 non-coding upstream 651941 22568987 ~ 22569106 (+)
XLOC_025276 NA non-coding upstream 1058565 22157933 ~ 22162482 (+)
XLOC_025301 NA non-coding downstream 425703 23665161 ~ 23668197 (+)
XLOC_025303 mir196b non-coding downstream 433919 23673377 ~ 23673455 (+)

Expression



Co-expression Network