XLOC_025322 (adsl)


Basic Information

Item Value
gene id XLOC_025322
gene name adsl
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 24207243 ~ 24218622 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00049983
AAAATGTGAAAGGAGAGTTCTTCAGATGAACTGAGGAGGGCAGCAAAAGGCATTAAATGGGACTTGTCTGCCGCAAataacagaagaagaagaagaacaaaacTTAATGCAGACTTGCGGTTCCCGTGCAGTCCGTGTGCGAGCTAGGCGCTCCGTTTAACCGCTGCAGGCATGGAGGGATCCGGAGAAGAGTTCCTGAAATACCGTTCACCGCTGGTGTCCCGGTACGCCAGCAAAGAGATGGCCTACAACTTCAGTGACAGGAAAAAATTTACCACATGGAGAAAGCTGTGGATTTATCTCGCGAAGGCCGAAAagTCTTTGGGCCTCCCCATAAGCGATGCTCAGGTAAGCGAGATGGAGTCTCACTCGGAGGACATTGATTTCGTTATGGCTGCGGAGGAGGAGAGGAAGCTCAGGCATGATGTCATGGCTCATGTGCACACATTCGCTCAATGCTGTCCCACCGCTGCTCCCATCATCCACTTGGGTGCTACTTCTTGTTATGTGGGTGACAACACGgATCTGATTATGCTACGCGATGGATTTGATATCCTGCTGCCCAAGTTGGCTCGTGTCATTGACAGACTGGCGAATTTTGCAGAGAAGTACGCTGACCTAACGACATTAGGCTTCACCCACTATCAACCTGCTCAGCTGACGACGGTGGGGAAGCGATCTTGTTTGTGGCTGCAGGATCTGCTCATGGACATGAGAAACCTTCAGCGGGCCAGAGACGACCTGCGCTTCAGGGGTGTTAAAGGAACCACTGGCACTCAGGCCAGCTTCCTGCAGCTCTTCCAGGGGGATCATGACAAGGTGGAGGAGTTGGATAAGATGGTCACTGAGATGGCTGGATTTAAAAAATCATATCTGGTGACCGGTCAGACGTACAGTCGGAAGGTGGACATTGACTCGCTCTGTGTGCTGTCCAGCCTAGCAGCCACAATACACAAGatttgcactGATATCCGTCTGCTGGCTAATCTAAAAGAGATTGAGGAGCCGTTTGAGAAAGAGCAAATTGGTTCCAGTGCCATGCCATACAAGAGGAACCCCATGCGTGCGGAGCGCTGCTGCAGTCTGGCCCGCCACCTGATGGCGCTGGTGTCCAATCCATTGCAGACGGCAGCAGTGCAATGGCTGGAAAGAACGCTGGACGACAGCGCTAACAGGAGGATCTCCTTGCCTGAGGCTTTTCTTACAGCTGATATCATCCtcagcacactgcagaacatcacTGAAGGCCTGGTGGTCTATCCTAAGGTGATTGAGAGGCACATCCGTCACGAGCTGCCCTTCATGGCTACTGAAAACATTATCATGGCCATGGTGAAGGCTGGAGGAAACAGACAGGACTGCCATGAGAAGATCCGTGTGCTGTCCCAGCAAGCTGCAGCCGTAGTCAAACAGGAAGGAGGAGATAATGACCTCTTGGCTCGGGTTCAAGCTGATCCATATTTCGCCCCCATATTAGGAGAGCTGGATGCCTTACTGGACCCCAAAACCTTCATCGGCCGAGCTCCACAACagGTTACTAGGTTTTTGTCTGAGGAGGTCAGGCCTGTTCTAGAGCCATACAAAAGTAAAATGGATGTGAAGATTGAACTGGAGCTCTGAAGCGCAAATGACTGTATGACTGACACATCAGAACTGTATgacaatgaataaatgtcaatCTGCAA
>TCONS_00049984
CGAGCTAGGCGCTCCGTTTAACCGCTGCAGGCATGGAGGGATCCGGAGAAGAGTTCCTGAAATACCGTTCACCGCTGGTGTCCCGGTACGCCAGCAAAGAGATGGCCTACAACTTCAGTGACAGGAAAAAATTTACCACATGGAGAAAGCTGTGGATTTATCTCGCGAAGGCCGAAAagTCTTTGGGCCTCCCCATAAGCGATGCTCAGGTAAGCGAGATGGAGTCTCACTCGGAGGACATTGATTTCGTTATGGCTGCGGAGGAGGAGAGGAAGCTCAGGCATGATGTCATGGCTCATGTGCACACATTCGCTCAATGCTGTCCCACCGCTGCTCCCATCATCCACTTGGGTGCTACTTCTTGTTATGTGGGTGACAACACGgATCTGATTATGCTACGCGATGGATTTGATATCCTGCTGCCCAAGTTGGCTCGTGTCATTGACAGACTGGCGAATTTTGCAGAGAAGTACGCTGACCTAACGACATTAGGCTTCACCCACTATCAcactatatatatattcctCTTTTGCTTGTCTATTTTTCAGCATACCTTTTCTGTTTTGGATTTAATACAGCAAAGTATTCTGGTTTTGggttctatttcccctctcctcgTCCCCATATTTTTCCTGCTTGTTCCCCGTGTTTTCAGACCTGCTCAGCTGACGACGGTGGGGAAGCGATCTTGTTTGTGGCTGCAGGATCTGCTCATGGACATGAGAAACCTTCAGCGGGCCAGAGACGACCTGCGCTTCAGGGGTGTTAAAGGAACCACTGGCACTCAGGCCAGCTTCCTGCAGCTC

Function

symbol description
adsl Predicted to enable (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity and N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity. Predicted to be involved in 'de novo' AMP biosynthetic process. Predicted to act upstream of or within purine ribonucleotide biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in adenylosuccinase lyase deficiency. Orthologous to human ADSL (adenylosuccinate lyase).

GO:

id name namespace
GO:0044208 'de novo' AMP biosynthetic process biological_process
GO:0006164 purine nucleotide biosynthetic process biological_process
GO:0006189 'de novo' IMP biosynthetic process biological_process
GO:0009152 purine ribonucleotide biosynthetic process biological_process
GO:0005829 cytosol cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity molecular_function
GO:0016829 lyase activity molecular_function
GO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko00230 Purine metabolism
ko00250 Alanine, aspartate and glutamate metabolism

ZFIN:

id description
ZDB-GENE-030131-6363 Predicted to enable (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity and N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity. Predicted to be involved in 'de novo' AMP biosynthetic process. Predicted to act upstream of or within purine ribonucleotide biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in adenylosuccinase lyase deficiency. Orthologous to human ADSL (adenylosuccinate lyase).

Ensembl:

ensembl_id ENSDARG00000017049

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00049983 False 1685 mRNA 0.51 13 24207243 24218622
TCONS_00049984 True 806 mRNA 0.50 5 24207382 24212272

Neighbor

gene id symbol gene type direction distance location
XLOC_025321 atf4b coding upstream 6424 24197934 ~ 24200819 (+)
XLOC_025320 prr15la coding upstream 9973 24189804 ~ 24197270 (+)
XLOC_025319 CR790362.1 coding upstream 22817 24161869 ~ 24184426 (+)
XLOC_025318 si:ch211-246i5.5 coding upstream 61993 24134418 ~ 24145250 (+)
XLOC_025317 NA coding upstream 73758 24121201 ~ 24133485 (+)
XLOC_025324 zgc:123244 coding downstream 1732 24220354 ~ 24226028 (+)
XLOC_025325 pdgfbb coding downstream 56975 24275597 ~ 24297419 (+)
XLOC_025326 pvalb6 coding downstream 78860 24297482 ~ 24434905 (+)
XLOC_025327 NA coding downstream 219975 24438597 ~ 24452013 (+)
XLOC_025328 cbx6b coding downstream 239582 24458204 ~ 24464794 (+)
XLOC_025429 BX649540.1 misc downstream 6030117 30248739 ~ 30249036 (+)
XLOC_025316 dre-mir-152 non-coding upstream 111207 24095957 ~ 24096036 (+)
XLOC_025313 NA non-coding upstream 239277 23930446 ~ 23967966 (+)
XLOC_025311 dre-mir-10c non-coding upstream 486498 23720651 ~ 23720745 (+)
XLOC_025342 NA non-coding downstream 711958 24930580 ~ 24936255 (+)
XLOC_025344 CR936416.1 non-coding downstream 837354 25055976 ~ 25060120 (+)
XLOC_025351 NA non-coding downstream 1090088 25308710 ~ 25308964 (+)
XLOC_025353 NA non-coding downstream 1354156 25572778 ~ 25573533 (+)

Expression


Co-expression Network