XLOC_025373 (hsp70.3)


Basic Information

Item Value
gene id XLOC_025373
gene name hsp70.3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 26123736 ~ 26127091 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050052
TTCGCGATAGAACTGTATACAGCGGAAAGCGAGACAGCGAGCGGACTGGGCCATCCAGACAACAAGCCATCAATACGCCTGACATAAAAGATCCAACAAACATAAAAGtTTCTTGAAATCAATCATGTCCTCTCCAAAAGGAATCGCTATTGGCATTGACCTGGGCACCACCTACTCCTGTGTGGGGGTGTTTCAGCATGGAAAAGTGGAGATCATCGCCAACGACCAGGGCAACAGAACAACACCCAGCTATGTTGCCTTCACAGACACAGAGAGGCTGATTGGAGACGCAGCTAAGAACCAGGTGGCCATGAATCCCAACAACACGGTGTTCGATGCCAAGAGGCTGATCGGCAGGAGGTTCGATGACCCTGTAGTGCAGTCTGACATGAAGCACTGGTCCTTCAAAGTCGTCAGTGATGGAGGAAAGCCAAAAGTTGCAGTGGAACACAAAGGAGAAAACAAGACCTTTAATCCTGAAGAGATTTCCTCCATGGTCCTGGTGAAGATGAAGGAGATTGCAGAGGCTTATCTGGGGCAGAAGGTGACCAACGCAGTTATCACAGTTCCAGCCTATTTCAACGACTCCCAGAGACAGGCCACTAAAGATGCTGGAGTCATCGCTGGACTGAACGTGCTCCGCATCATCAATGAGCCCACGGCTGCAGCCATCGCCTACGGCCTGGACAAAGGCAAATCCTCAGAGCGCAACGTGCTGATCTTTGACCTGGGCGGAGGCACCTTCGACGTGTCTATCCTGACCATCGAAGACGGCATCTTTGAGGTGAAGGCCACCGCTGGAGACACTCATCTGGGCGGTGAGGACTTTGACAACCGCATGGTGAACCACTTTGTGGAAGAGTTCAAGAGGAAGCACAAGAAGGACATCAGTCAGAACAAGAGGGCCCTGAGGAGACTGCGAACCGCATGCGAACGAGCCAAGAGGACGCTCTCGTCCAGCTCTCAGGCCAGCATTGAGATCGACTCTCTGTACGAGGGCATCGACTTCTACACGTCCATCACCAGAGCTCGCTTCGAGGAGCTCTGCTCCGACCTCTTCAGGGGAACGCTTGATCCTGTGGAGAAAGCACTGAGGGACGCCAAGATGGACAAGGCTCAGATCCACGACATCGTGCTGGTTGGGGGATCAACAAGAATCCCAAAGATCCAGAAGCTTCTGCAGGATTTCTTCAACGGCAGAGAACTGAACAAGAGCATTAACCCTGATGAAGCGGTGGCTTACGGTGCCGCGGTGCAGGCCGCCATCCTCATGGGCGACACCTCTGGAAACGTGCAGGACCTGCTGCTGCTGGACGTGGCCCCACTGTCTCTGGGTATTGAGACCGCAGGTGGAGTCATGACGGCCCTCATCAAGCGCAACACAACTATCCCCACCAAACAGACCCAGACCTTCACCACCTACTCCGACAACCAGCCCGGCGTCCTGATCCAGGTGTTCGAGGGAGAAAGAGCCATGACCAAAGACAACAACCTGCTGGGCAAATTTGAGCTGACGGGAATTCCACCTGCGCCACGTGGCGTCCCGCAGATCGAAGTGACCTTCGACATCGACGCCAACGGGATCCTAAATGTGTCGGCGGCGGACAAAAGCACCGGAAAACAGAACAAGATCACCATCACCAACGACAAGGGCAGGCTGAGCAAAGAGGAGATCGAGAGAATGGTGCAGGAGGCCGACAAGTACAAAGCTGAAGACGATCTGCAGAGAGAGAAGATTTCTGCCAAAAACTCCCTGGAGTCTTACGCCTTCAACATGAAGAACAGTGTGGAAGACGACAACCTGAAAGGCAAGATCAGCGAGGAGGACAAGAAGAGGGTTATTGAGAAGTGCAATGAAGCCGTGAGCTGGCTGGAGAACAACCAGCTGGCGGATAAAGAGGAGTACGAACATCAGCTGAAGGAGCTGGAGAAAGTCTGCAATCCAGTCATCTCCAAACTCTACCAGGGAGGGATGCCAGCTGGAGGATGTGGAGCTCAGGCACGGGGCGCATCAGGGGCCAGCGCTCAGGGGCCCACCATTGAAGAGGTGGATTAAAACTCCTCATGAACTGAACAAACTAGACAAAAAAATAATTCTTTGATTATTTTAAGATGACTTTATTTAAAGTCTTATTGCACAGTGTGTTGGTTCACTATCTACTTAAACATCTTGATAcagtaaaatgtttacatttattaaataatgttaaactttaatttattttttgtttagacCAAAAATAAGCTTGACCATTTTAAGAAATTGtagtttagttttcatttttcattcatgTTCATGTTGTTACATGTGACAAATTtgtgataaaaatgtgttaataaaagtgtttgtttttttaa

Function

symbol description
hsp70.3 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and misfolded protein binding activity. Acts upstream of or within camera-type eye morphogenesis. Predicted to be active in cytosol; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to several human genes including HSPA1B (heat shock protein family A (Hsp70) member 1B).

GO:

id name namespace
GO:0006986 response to unfolded protein biological_process
GO:0016192 vesicle-mediated transport biological_process
GO:0048593 camera-type eye morphogenesis biological_process
GO:0034620 cellular response to unfolded protein biological_process
GO:0051085 chaperone cofactor-dependent protein refolding biological_process
GO:0042026 protein refolding biological_process
GO:0008180 COP9 signalosome cellular_component
GO:0005829 cytosol cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0044183 protein folding chaperone molecular_function
GO:0051787 misfolded protein binding molecular_function
GO:0031072 heat shock protein binding molecular_function
GO:0031625 ubiquitin protein ligase binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016887 ATPase activity molecular_function
GO:0051082 unfolded protein binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-110713-1 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and misfolded protein binding activity. Acts upstream of or within camera-type eye morphogenesis. Predicted to be active in cytosol; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to several human genes including HSPA1B (heat shock protein family A (Hsp70) member 1B).

Ensembl:

ensembl_id ENSDARG00000021924

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050052 True 2358 mRNA 0.50 2 26123736 26127091

Neighbor

gene id symbol gene type direction distance location
XLOC_025371 NA coding upstream 43336 26076494 ~ 26080400 (+)
XLOC_025370 si:dkeyp-69e1.8 coding upstream 52935 26064091 ~ 26070801 (+)
XLOC_025369 hmgxb4a coding upstream 63689 26044969 ~ 26060047 (+)
XLOC_025368 ankrd54 coding upstream 78977 26035550 ~ 26044759 (+)
XLOC_025367 foxred2 coding upstream 91024 26019426 ~ 26032712 (+)
XLOC_025374 FP016144.1 coding downstream 67253 26194344 ~ 26194459 (+)
XLOC_025375 nudt9 coding downstream 96285 26223376 ~ 26232773 (+)
XLOC_025376 atad5a coding downstream 117262 26244353 ~ 26266464 (+)
XLOC_025377 adap2 coding downstream 140634 26267725 ~ 26281561 (+)
XLOC_025378 rhot1a coding downstream 161890 26288981 ~ 26319758 (+)
XLOC_025429 BX649540.1 misc downstream 4121648 30248739 ~ 30249036 (+)
XLOC_025364 NA non-coding upstream 136792 25985339 ~ 25986944 (+)
XLOC_025360 FP101990.1 non-coding upstream 278408 25844151 ~ 25845328 (+)
XLOC_025358 BX120006.1 non-coding upstream 370187 25752221 ~ 25753549 (+)
XLOC_025357 BX120006.2 non-coding upstream 376818 25745636 ~ 25746918 (+)
XLOC_025382 NA non-coding downstream 228203 26355294 ~ 26361798 (+)
XLOC_025383 NA non-coding downstream 284142 26411233 ~ 26416784 (+)
XLOC_025384 NA non-coding downstream 508729 26635820 ~ 26636398 (+)
XLOC_025390 NA non-coding downstream 1167217 27294308 ~ 27343689 (+)

Expression


Co-expression Network