XLOC_025386 (socs1a)


Basic Information

Item Value
gene id XLOC_025386
gene name socs1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 26813058 ~ 26814953 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050079
ATTCTGACATTACAAAGAGCAGAAAGCAAGAGCACAGAGTTTGAGGTCGCGCTCTGAGGAAACCTCTAACGAGATATAACGGTGGAATAAATCAATGGGAGTTCTAAAACGCCCGATTTTGGAAGCGGCGACGAGAGTTTGTCAGAGGCAAAGTTGTATTGCCTGCTCTTGGAGTACTTGTTTACTAAAACGACCGATGAGTCTCATCTAGATGACCTTCCTGTGGTACAGTATGGAAGACCACGCCGGTTGGTCTTTCCTGTAGGATGGTGGCGCACAGTTCAGTGGAAGGGAATCAAGGCATAGAAGATCGCCAAGTGAGCACTGAGGCCTCCTCAGACGTCTTCCAATCCCAAAGATCCAGGCCCAGGCAGAGTACCGTGGCTTTCCAGACACATTTCAAGCCGTTCAACTATGCAAGAGACTTCAAGATCATTTCCAACACCACCTCGATGCTAGAGGAGAGTGGCTTTTATTGGGGTCCCATGACTGTGGAGGAAGCACACCTGAAGCTGAAGAAAGAGTCAGTGGGAACTTTCCTGATCCGGGACAGTCGTCAGAGCGACGTTTTCTTTACACTGAGTTACAAAGCACAAAACGGTCCCGTCAGCATCCGGATTAACTTCAAGAATTCCAAATTCAGCCTGACAGGAAGCAAGGAATCTTTTGACTCTCTTTTCAAACTGCTGGAACACTACATCAGTTCCCCAAAGAAGGGACTCATTCGGCCCTGCAGGAAAGAGCCAGTGCAGTCCCTGCAGCAGTTGTGCCGGAGACAGATTATGGAAAGATGCGACGGAAAAGACATCGACTGCATCCCTGTGCAACCAATCCTCAAAGACTTCCTCCATGCCTTCCCTCATCCGCTATGAAGACGAGACTTGTTGCATTAAAGCGCTGCTGGAATATTCTGGAGATACTTGATGGACTCCTCGTGGTCCTGCTCCGTTTTAGGATGCAGGAATCGCACTGTAGCACATTTTGGAATATCAGACTTGAACACTGCACAATGAAAGTTTACGTTGTCTGTGAATGTTTACACTATATGGAAATGCTGTTTTCCTGTTATCGTTACATTTCTGCTATGCAGAGCGAAATATTTCAAGAGAGTaagttttataaaattaataaatatatttttaaactatttaaaa
>TCONS_00050080
GTATGGAAGACCACGCCGGTTGGTCTTTCCTGTAGGATGGTGGCGCACAGTTCAGTGGAAGGGAATCAAGGCATAGAAGATCGCCAAGTGAGCACTGAGGCCTCCTCAGACGTCTTCCAATCCCAAAGATCCAGGCCCAGGCAGAGTACCGTGGCTTTCCAGACACATTTCAAGCCGTTCAACTATGCAAGAGACTTCAAGATCATTTCCAACACCACCTCGATGCTAGAGGAGAGTGGCTTTTATTGGGGTCCCATGACTGTGGAGGAAGCACACCTGAAGCTGAAGAAAGAGTCAGTGGGAACTTTCCTGATCCGGGACAGTCGTCAGAGCGACGTTTTCTTTACACTGAGTTACAAAGCACAAAACGGTCCCGTCAGCATCCGGATTAACTTCAAGAATTCCAAATTCAGCCTGACAGGAAGCAAGGAATCTTTTGACTCTCTTTTCAAACTGCTGGAACACTACATCAGTTCCCCAAAGAAGGGACTCATTCGGCCCTGCAGGAAAGAGCCAGTGCAGTCCCTGCAGCAGTTGTGCCGGAGACAGATTATGGAAAGATGCGACGGAAAAGACATCGACTGCATCCCTGTGCAACCAATCCTCAAAGACTTCCTCCATGCCTTCCCTCATCCGCTATGA

Function

symbol description
socs1a Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within several processes, including positive regulation of T cell migration; regulation of signal transduction; and regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including brain; digestive system; musculature system; pleuroperitoneal region; and visual system. Used to study fatty liver disease and hyperinsulinism. Human ortholog(s) of this gene implicated in ovarian carcinoma; prostate cancer; and urinary bladder cancer. Orthologous to human SOCS1 (suppressor of cytokine signaling 1).

GO:

id name namespace
GO:2000406 positive regulation of T cell migration biological_process
GO:0060334 regulation of interferon-gamma-mediated signaling pathway biological_process
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway biological_process
GO:0032868 response to insulin biological_process
GO:0046854 phosphatidylinositol phosphorylation biological_process
GO:0042509 regulation of tyrosine phosphorylation of STAT protein biological_process
GO:0016567 protein ubiquitination biological_process
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT biological_process
GO:0051896 regulation of protein kinase B signaling biological_process
GO:0035162 embryonic hemopoiesis biological_process
GO:0060042 retina morphogenesis in camera-type eye biological_process
GO:0005942 phosphatidylinositol 3-kinase complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040801-205 Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within several processes, including positive regulation of T cell migration; regulation of signal transduction; and regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including brain; digestive system; musculature system; pleuroperitoneal region; and visual system. Used to study fatty liver disease and hyperinsulinism. Human ortholog(s) of this gene implicated in ovarian carcinoma; prostate cancer; and urinary bladder cancer. Orthologous to human SOCS1 (suppressor of cytokine signaling 1).

Ensembl:

ensembl_id ENSDARG00000038095

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050079 False 1154 mRNA 0.46 2 26813058 26814953
TCONS_00050080 True 642 mRNA 0.50 1 26814030 26814671

Neighbor

gene id symbol gene type direction distance location
XLOC_025385 tmc5 coding upstream 61239 26734162 ~ 26751819 (+)
XLOC_025384 NA coding upstream 176660 26635820 ~ 26636398 (+)
XLOC_025383 NA coding upstream 396274 26411233 ~ 26416784 (+)
XLOC_025382 NA coding upstream 451260 26355294 ~ 26361798 (+)
XLOC_025381 rps15a coding upstream 461402 26345732 ~ 26351656 (+)
XLOC_025387 dexi coding downstream 90071 26905024 ~ 26906351 (+)
XLOC_025388 emp2 coding downstream 212828 27027781 ~ 27056180 (+)
XLOC_025389 grin2aa coding downstream 256796 27071749 ~ 27277695 (+)
XLOC_025390 NA coding downstream 479355 27294308 ~ 27343689 (+)
XLOC_025391 NA coding downstream 531886 27346839 ~ 27494805 (+)
XLOC_025429 BX649540.1 misc downstream 3433786 30248739 ~ 30249036 (+)
XLOC_025374 FP016144.1 non-coding upstream 618599 26194344 ~ 26194459 (+)
XLOC_025371 NA non-coding upstream 732658 26076494 ~ 26080400 (+)
XLOC_025392 BX000529.1 non-coding downstream 592143 27407096 ~ 27407211 (+)
XLOC_025393 NA non-coding downstream 779420 27594373 ~ 27601473 (+)
XLOC_025402 NA non-coding downstream 1834994 28649947 ~ 28733765 (+)

Expression


Co-expression Network