XLOC_025421 (cacng2a)


Basic Information

Item Value
gene id XLOC_025421
gene name cacng2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 29714775 ~ 29845175 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050151
ACACATCAAATCTACGCGCCTAAATTGTCATAATTAAGAGCGAGCATTGGCTTAATTGCTGTGGCGTTTGAATGACATGCCCAGGCCATTACTAAAGGCCTGTGCAATTAATTATTATCTTTGATTAGTGGCTTTGCGGCGTGAATGTTCGCGTAAGTTTAAGCTGTAGCACTAGCTGCTGCATATCTTTACCTCGTTTAGAAAAAAGACAAGGACAAACGATTCGGAAGGGTAGAATTGCTCTTTGTTGGAACAGCGCGTAAAGCGTACCGTTCCTCCCTCCCAAAACAGCCTAAAAGGCTCACCTATTTCTTCCTTAATCGTTCTCACCCAAACGCAACCATAAGGTTCCTACCGCATCCTCCCCCTTCCCCCTCCTTTCGCTCAAATATATCCCATTTTTTAAATTTGGTTTGGTCCCgtaaattttcaaatatttatttcctATACATCAAGAGGAAAGGGGGTCCCCCTTTCATGGAATGCGGAAACATGGGTGTGTTTGACCGCGGAGTTCAGATGTTATTGACCACGGTGGGCGCGTTCGCTGCCTTCAGTCTCATGACCATCGCGGTGGGCACGGACTACTGGCTGTACTCGCGCGGCGTCTGTAAGATCAAGACCAACAACGAGAACGAGACCAGCAAGAAGAACGAAGAGGTGATGACCCACTCGGGACTGTGGAGGACATGTTGCTTGGAAGGAAACTTCAAAGGATTGTGTAAGCAGATAGATCACTTTCCAGAAGACACAGATTATGAAGCAGATGCCTCAGAGTACTTCTTACGAGCCGTGCGAGCGTCTAGTATCTTCCCCATCCTCAGCGTCATCCTGCTCTTCATGGGTGGTCTCTGTATAGCTGCCAGCGAGTTCTACAAGTCCCGCCACAATATCATCCTCAGTGCAGGAATCCTCTTCGTGTCTGCAGGCCTCAGTAACATCATTGGCATGATCGTGTACATATCAGCCAATGCGGGGGATCCCTCAAAGAGCGACTCCAAGAAGAACAGCTACTCATACGGCTGGAGTTTCTACTTTGGTGCTTTGTCCTTTATCATGGCTGAAATGGTGGGTGTGCTGGCCGTGCACATGTTCATCGACCGGCACCGGGAGCTGCGGGCGGGCGCGCGGGCAGCAGATTACCTGCAGGGCTCGGCTATCACGCGCATCCCCAGTTACCGGTATCGCTACCGGCGCCGCTCCCGCTCATCGTCCCGCTCCACGGACCCCTCGCATTCCCGAGACGCCTCGCCGGTGGGATTGAAGGGTTTCGGGGCTCTACCTTCCACCGAGATTTCCATGTACACACTCACCCGCGGGGGAGACACCCTAAAGGGCGGCCACGGCACCCCCACCGCCACCTACAATTCAGAGAGGGACCACAACTTCCTCCAGGTCCACAACTGCATCCAGAAGGACCTGAAAGACTCATCCAACACAGCCAACCGACGCACCACCCCTGTATGAGGCACAACCTCTCCCCGTACAGATAGCAGGGCAAGGGAGACGGGAGCGGAGGCCTGGAATATTACAGATCAAACTTCATGTACCATGCGTTTTCACGATTCGGAGGAACCGGGAGGATTTTTGCGTTTCGATCAAAGATTACACATGTATGCATGATTTTGCCATTTGCCATTGACAAATTGAGGCTGGTTTGAAATGGAGACAGGCGATAAGAGATTTGCAGAAGGGTTCTTTCAGCCTGTGACGTGGGAGCTGTAGCTTGTGGCAttgatttgacatgtttttgttAAGAAAGCATTCCTTCAGCACCCATCGGTCTACACGGATCATCAGCAAGCTACTGCTCCCTCATAAGTCTTCTTCCCTTCTCCACTATATTCgtcatattcatttatttgttcatttgttattTGCATTCAAAGAAAAAatgagaaagaaacaaaaaaaaactgtgaaccaCCGCAGTAGGGTGTTCAGTAAGAAACAGCCCGGTCTGCAATCTCTTACACAAGGTACaacatatatatacacgtatagtatatatatatggatgtatTGATTTTATATAGAAATTAACATAATAATCAAGACTTTTCTGAGGTAAAACTGCTGTTTGCCGGGTAATGATCTGTTGGGAAAAGAGACTCTGTGGCCCTGAGCTGCGACTGTGGCCGGACGATGGATGAAATCATGGAGGATCTTCACCGCAAAGCTGCTCTAACACGAGACTGACAAAGACGTTCAACCTTAGACAAAAATCTATTCTTTTAAAAGAACCTTCTCATCTTTTTCTCAGTCCCTGTTTGCTTcctttttttctctcctctcGCATTCGGTCGTCACGAGAGCGaacaacagaaacaaaaaaaaacttacgcAAAGACCTTCGCTGACAAACAGAGGGTCAGAGTTCGCTGAAAGACTCCAGAAATGACTGCCAAGACGAAAAAAAGGAAGGAGGAGGGGGGAGGAAAAGAAGAGGATGCTGAACTCTAAACAAACACTTGCAGGAACGCAAGCGACAAACAAAAGTACGAAATATTACGAGAAACGAAGCTAAGTGACTCACGAATACAAAGATTAAATGCATGCTATAAATTTACAGCAAACCTGCTCTTGAAACTTAAGTTTTAAaggataatgataattataaaggGAAAAGCAATGTTAAAAAAAGTTAACTCTTAATGTTTTGTGTACTCTTTCTGTTTtggtttctattattattattattattattattatttattattataattaatcattataataatatactTTGATGATAAACCAAGCGAACAAATTACagcaaaactgctttttttcaatTCTGACTTCTTTCTTTGTATCCACGTGTTTTTCTTTTACTCAGAATCACACGCCTTAGTCATTTCATctttctttggattcattttaaaatgtgtcattttcttTGAAATGAAATCTAAAGGTGCCAAAACAGAATGATCCTAAACTTGGATGCATCAAGTCCTGATGAATAAACAGACAAACCCAAGGGGGAACAAA

Function

symbol description
cacng2a Predicted to enable channel regulator activity and voltage-gated calcium channel activity. Acts upstream of or within AMPA selective glutamate receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in postsynaptic density membrane. Is expressed in brain and central nervous system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 10. Orthologous to human CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2).

GO:

id name namespace
GO:0051968 positive regulation of synaptic transmission, glutamatergic biological_process
GO:0019226 transmission of nerve impulse biological_process
GO:0034765 regulation of ion transmembrane transport biological_process
GO:0070588 calcium ion transmembrane transport biological_process
GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome biological_process
GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping biological_process
GO:2000311 regulation of AMPA receptor activity biological_process
GO:0098990 AMPA selective glutamate receptor signaling pathway biological_process
GO:0006811 ion transport biological_process
GO:0006816 calcium ion transport biological_process
GO:0099590 neurotransmitter receptor internalization biological_process
GO:0098839 postsynaptic density membrane cellular_component
GO:0005891 voltage-gated calcium channel complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0032281 AMPA glutamate receptor complex cellular_component
GO:0005244 voltage-gated ion channel activity molecular_function
GO:0005245 voltage-gated calcium channel activity molecular_function
GO:0016247 channel regulator activity molecular_function
GO:0005262 calcium channel activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1401 Predicted to enable channel regulator activity and voltage-gated calcium channel activity. Acts upstream of or within AMPA selective glutamate receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in postsynaptic density membrane. Is expressed in brain and central nervous system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 10. Orthologous to human CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2).

Ensembl:

ensembl_id ENSDARG00000032565

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050151 True 2994 mRNA 0.45 4 29714775 29845175

Neighbor

gene id symbol gene type direction distance location
XLOC_025420 NA coding upstream 4553 29687549 ~ 29710222 (+)
XLOC_025419 CT573429.1 coding upstream 43122 29664357 ~ 29671653 (+)
XLOC_025418 eif3d coding upstream 59850 29640837 ~ 29654925 (+)
XLOC_025417 NA coding upstream 74481 29639984 ~ 29640294 (+)
XLOC_025416 sstr3 coding upstream 112296 29600917 ~ 29602479 (+)
XLOC_025422 BX901883.7 coding downstream 35860 29881035 ~ 29895974 (+)
XLOC_025423 NA coding downstream 69269 29914444 ~ 29915357 (+)
XLOC_025424 BX901883.3 coding downstream 84407 29929582 ~ 29929887 (+)
XLOC_025425 ifi35 coding downstream 96602 29941777 ~ 29948955 (+)
XLOC_025426 NA coding downstream 121608 29966783 ~ 29967070 (+)
XLOC_025429 BX649540.1 misc downstream 403564 30248739 ~ 30249036 (+)
XLOC_025412 BX649558.1 non-coding upstream 304816 29406013 ~ 29409959 (+)
XLOC_025411 NA non-coding upstream 316624 29393465 ~ 29398151 (+)
XLOC_025431 CR936968.2 non-coding downstream 509593 30354768 ~ 30355587 (+)
XLOC_025432 NA non-coding downstream 652546 30497721 ~ 30506149 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G275519 NA non-coding CI01000069 null 2065208 ~ 2155034 (-)
bowfin (Amia calva) AMCG00014888 cacng2,LOC103372897,LOC102214005,LOC101463732,LOC100710835,LOC108237679 coding CM030128.1 CM030128.1 38363902 ~ 38402794 (-)