XLOC_025440 (prf1.9)



Basic Information


Item Value
gene id XLOC_025440
gene name prf1.9
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 30968176 ~ 30975502 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00050173
CCGATTAATTATGCCTGCGGTGCCAATCCATTCATGCCACCTCTGTATTAAACAATGACATGAACGCACTTCAAAAGTGCTTCATAAAAGTTATGCCTGCTCTGACACACTTTAAATCCAAGTAAAAATGCAGAAATAATAGCAGTAAATACAATGAAACcattaatttgtgtttaatataatGGTCTAAATATCACCTTTGCTCATGGTTTTGCTGAATTAAAACCACATCCTTTTATGCTAAATAACAACCTTTATCAATATTTCCAACCCTATGCATCCTGCATACACATTGACCATAAAGGTGTGAATGCTCTCAAGTCTGACCAGGGGTGAGatgtaaactgtggtgtataAATATGAACACAGCACAGATACTTGATCTAAGTCTGCATGTGGGACACTCTTAGACTAATGATTCTGAAGACCCTCTGGGAAACTCACAATGGTTCCTGTAGCTCTACTGTGCTCTGTGCTTCTTCTATACCTTACTCCTCCAACCAGCCCAGCATGCTTTCTGGGAAAACAAGCAGAGTGTCAAGATGCCAGTTTTGTGCCAGGATCTGACTTGGCTGGGGAGGGATTCGACATTACTAAGATGCAACGCCTGGGGACCTTTGTCTTCGACATGAGTAAGTGGGATCTCAATAACAACACGTGTAATCTGTGCAAAAACCCATTCATGCAGAACGAAAAGCAGAAGCTCCCGGTGTCAGCCGTCTACTGGAGGGCATCTCAAAAGTGCACCATGTCCCTATCCAGCTCTGTTTATGAGTCCAGCGAGTCCCTGGTCAGTTCCAGCACCTCCTCCATAGAGAACAACTGGAAAACTGGACTGGGAATAGGAAATATGTTAAGTAAGGTGTCTCTGATGGTTGCTGGAACTAACTCAAGGCTTTCTGACTATTCAATGAGCAAGACCAAAAAGGACAAATTCAGCTTCATCAAGCAGTCTGCATCCTGCGTGTACTACAGCTACAGGATTGCCAGCAGCGCTCCTCTTCACCATGAACTAAGAGATGACTTCAGTAACCTTCCAGCGACGTATGACAACCAGACAAAAGAGAGCTACCTGTCACTCGTTGAAAAGTTTGGCACACATTACATTATCCAGGTAAAACTGGGTGGAGGTGTGCAGTCTGTCACCAGTGTTAAACAATGCATGGCGActctacaagacctcagtgtaGATGAGGTCAAAACATGCTTGGACGTCGAAGCATCTGCAAGTGTGATGGGGAGGATAAGTGTAGACACAGCTTATCGTCACTGTAAACAGAGCCAAGACAAAAAACTGAGCGCACACAGCTTTGCTAACAGTTTCAGTGATAGGTTAACAGAAATCACCGGTGGCCATACTCAAGACAGCGCTCTTCTCTTCTCAGCCAGCAATGACCCTGGTGCTTATAAACAGTGGCTCTCCTCAGTGCCTCAACAGCCAGACGTGATATCCTTCTCACTGAAACCCCTCCACATGCTAATGCCAGCCAAAAACCCCAAACGCGATCAACTACGCCGTGCCATTCATGACTACGTCCTGCAGAAGGCCCTCTTGAAGAATTGCTCTTCACCCTGCAAAACCGGCATCGCGACAAACCCCAAAGAGCCCTGCGCTTGCAGCTGCCACAACAATCCTGCTGTCAAAGCCAACTGCTGTCCCGCACAACGAGGAATTGCCCAAATTACAGTGACTGTaatgagagccacaggtctgTTCGGCGACTATTTTACCTGGACCGATGGCTACGTCAAGGTCTTTCGAAATCAAAAGCTCTTTTTAGGGGAAACGCCAGTGATCTGGAACCAGAACTCACCAAAGTGGAACTGGAGGTTTGATCTTGGGAGCTTTGTTGTTTCTCAGTTTGGGGGATTGAAATTAGAAGTTTGGGATAGGGATAATAAGTGGGATGATGATCTTTTGGGGACGTGCAACATTCAGCTGAAGGCCGGTGTAAAAAATGATTTCTGTCGACTCAATCATGGTTTGCTGTATTTTAAGACGTCTGTGACGTGTGGGCCTAGTTTGGCGGGCTCCTCGTGCACTGAGTATGTGGGATCTCCGATGGCGTCCCACTTGGAGAAGCTCTACGTGTCGAGACATGCAAGACCTGTCCCGAAAGATATGCTGGTGAAAATGGGGGTGCTCTTAAAGGAGCGTCGAGCCCTGTTGGGTCAGACCAGTGAGGCTGAAAGCAAAAGGCAGAATTTGTGAACAACAAGAATGCTAGTCTCTCGTAAATCTCGTTACTTGTTAGATGCAGCAAGAagcatttaaatttaattcatttagcaGATATATATTAGCATACacttatacatacagttgaagtcagaattattagccgtcctgaattattaacccatctcaatattttcttttcaatttctgtttaacgcaaaaaaaaaatttcaacgcatttataaacataatagttataataactcatctctattaactgatttattttatctttgctatgatgacagtaaatatttatttctagttatttactagtattcagcttaaaatgggATCTAAAGGCTTAAAGAGCCCTTATTTTGTCTTATAAAagttcatattttggttttgggggtcttcaACAAAAGCCTTAGATGCAAGCAAGGTCAAAAaccctttcattgtcttatagtatatatttatttttaccttattatcccaatgactcctatattattcatttagtgattcatttgttcccaaacccctaagctaatctgctgtgattggtctgatgacccagtctgttgtgattggtcaactgcgttcagcgtgagacagagagaaacacccAGCATGGCTATGAAATGGCAGAGTATGtaagagcccaatgcaggagtgtgttaaagcaatgcagttaaagaCCGAGAGATCCGAACCAAACACGATTAATTGATTggactctgagtcgactatttcattaaagaattaacagttttaaacacggtgcacttatAGATTTAATcctcagcaggatgttttcagtcacttagagctgtgttacacactgcatgaaagtTCATCTTCAAAAACTCATAATAGGGACtctttaactaggttaactaggcaggttagggtaattaggcaagttattgtataacagtgatttgttctgtagactattgaaaaaaaatgtattccttaagggggctaataatattgaccttaaaatggttttaaaaactgcttttattctagccaaaattattcagataagactttttccacaagaaagaatattataggaaatactgtgaaaaaattaatTGCTGTGTTCCTTTGAGGAAatgtttgaaaagaaaaaaaaaataccggagggctaataattttgacttcaactgcacatgcagttttatattttgtatctcagcattgcattttatttgtatcaattttgctttgatttacagATTTAGATGTTTGATGTATTCTATGCTTGCAGATTGTTATTTGTCCATTGCTTGCAGATATTTGgctaataaaataattagaaGCACAGCAGCTTCAGTGATTCTTTAAAATGATTACTgtcattggtaacactttagtttaggtcacaattcacggtattaacaaaccatttactcaataaactactgtttataaaTAGTAAGCtagaagttgggtttagatattgggtaggattagggctg
>TCONS_00050174
ATGTTTCAATGCAATCTTATTTTCTCTAGGAAACTCACAATGGTTCCTGTAGCTCTACTGTGCTCTGTGCTTCTTCTATACCTTACTCCTCCAACCAGCCCAGCATGCTTTCTGGGAAAACAAGCAGAGTGTCAAGATGCCAGTTTTGTGCCAGGATCTGACTTGGCTGGGGAGGGATTCGACATTACTAAGATGCAACGCCTGGGGACCTTTGTCTTCGACATGAGTAAGTGGGATCTCAATAACAACACGTGTAATCTGTGCAAAAACCCATTCATGCAGAACGAAAAGCAGAAGCTCCCGGTGTCAGCCGTCTACTGGAGGGCATCTCAAAAGTGCACCATGTCCCTATCCAGCTCTGTTTATGAGTCCAGCGAGTCCCTGGTCAGTTCCAGCACCTCCTCCATAGAGAACAACTGGAAAACTGGACTGGGAATAGGAAATATGTTAAGTAAGGTGTCTCTGATGGTTGCTGGAACTAACTCAAGGCTTTCTGACTATTCAATGAGCAAGACCAAAAAGGACAAATTCAGCTTCATCAAGCAGTCTGCATCCTGCGTGTACTACAGCTACAGGATTGCCAGCAGCGCTCCTCTTCACCATGAACTAAGAGATGACTTCAGTAACCTTCCAGCGACGTATGACAACCAGACAAAAGAGAGCTACCTGTCACTCGTTGAAAAGTTTGGCACACATTACATTATCCAGGTAAAACTGGGTGGAGGTGTGCAGTCTGTCACCAGTGTTAAACAATGCATGGCGActctacaagacctcagtgtaGATGAGGTCAAAACATGCTTGGACGTCGAAGCATCTGCAAGTGTGATGGGGAGGATAAGTGTAGACACAGCTTATCGTCACTGTAAACAGAGCCAAGACAAAAAACTGAGCGCACACAGCTTTGCTAACAGTTTCAGTGATAGGTTAACAGAAATCACCGGTGGCCATACTCAAGACAGCGCTCTTCTCTTCTCAGCCAGCAATGACCCTGGTGCTTATAAACAGTGGCTCTCCTCAGTGCCTCAACAGCCAGACGTGATATCCTTCTCACTGAAACCCCTCCACATGCTAATGCCAGCCAAAAACCCCAAACGCGATCAACTACGCCGTGCCATTCATGACTACGTCCTGCAGAAGGCCCTCTTGAAGAATTGCTCTTCACCCTGCAAAACCGGCATCGCGACAAACCCCAAAGAGCCCTGCGCTTGCAGCTGCCACAACAATCCTGCTGTCAAAGCCAACTGCTGTCCCGCACAACGAGGAATTGCCCAAATTACAGTGACTGTaatgagagccacaggtctgTTCGGCGACTATTTTACCTGGACCGATGGCTACGTCAAGGTCTTTCGAAATCAAAAGCTCTTTTTAGGGGAAACGCCAGTGATCTGGAACCAGAACTCACCAAAGTGGAACTGGAGGTTTGATCTTGGGAGCTTTGTTGTTTCTCAGTTTGGGGGATTGAAATTAGAAGTTTGGGATAGGGATAATAAGTGGGATGATGATCTTTTGGGGACGTGCAACATTCAGCTGAAGGCCGGTGTAAAAAATGATTTCTGTCGACTCAATCATGGTTTGCTGTATTTTAAGACGTCTGTGACGTGTGGGCCTAGTTTGGCGGGCTCCTCGTGCACTGAGTATGTGGGATCTCCGATGGCGTCCCACTTGGAGAAGCTCTACGTGTCGAGACATGCAAGACCTGTCCCGAAAGATATGCTGGTGAAAATGGGGGTGCTCTTAAAGGAGCGTCGAGCCCTGTTGGGTCAGACCAGTGAGGCTGAAAGCAAAAGGCAGAATTTGTGAA

Function


symbol description
prf1.9 Predicted to enable calcium ion binding activity. Predicted to act upstream of or within cytolysis and immune response. Predicted to be part of membrane attack complex. Is expressed in gill and kidney. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; familial hemophagocytic lymphohistiocytosis 2; human immunodeficiency virus infectious disease; multiple sclerosis; and non-Langerhans-cell histiocytosis. Orthologous to human PRF1 (perforin 1).

GO:

id name namespace
GO:0006955 immune response biological_process
GO:0019835 cytolysis biological_process
GO:0005579 membrane attack complex cellular_component
GO:0005509 calcium ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-131127-344 Predicted to enable calcium ion binding activity. Predicted to act upstream of or within cytolysis and immune response. Predicted to be part of membrane attack complex. Is expressed in gill and kidney. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; familial hemophagocytic lymphohistiocytosis 2; human immunodeficiency virus infectious disease; multiple sclerosis; and non-Langerhans-cell histiocytosis. Orthologous to human PRF1 (perforin 1).

Ensembl:

ensembl_id ENSDARG00000060662

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00050173 False 3672 mRNA 0.41 5 30968176 30975502
TCONS_00050174 True 1807 mRNA 0.48 4 30968883 30974043

Neighbor


gene id symbol gene type direction distance location
XLOC_025439 NA coding upstream 19722 30943288 ~ 30948454 (+)
XLOC_025438 cldni coding upstream 41174 30921246 ~ 30927002 (+)
XLOC_025437 NA coding upstream 60050 30907892 ~ 30908126 (+)
XLOC_025436 NA coding upstream 95016 30868418 ~ 30873160 (+)
XLOC_025435 NA coding upstream 272369 30694174 ~ 30695807 (+)
XLOC_025441 prf1.1 coding downstream 5350 30980852 ~ 30988333 (+)
XLOC_025442 cox6a2 coding downstream 64421 31039923 ~ 31042102 (+)
XLOC_025443 si:dkey-66i24.7 coding downstream 82962 31058464 ~ 31060609 (+)
XLOC_025444 si:dkey-66i24.8 coding downstream 112007 31087509 ~ 31090561 (+)
XLOC_025445 si:dkey-66i24.9 coding downstream 117953 31093455 ~ 31097530 (+)
XLOC_025429 BX649540.1 misc upstream 719140 30248739 ~ 30249036 (+)
XLOC_025434 NA non-coding upstream 312618 30643162 ~ 30655558 (+)
XLOC_025446 NA non-coding downstream 122431 31097933 ~ 31105653 (+)
XLOC_025447 NA non-coding downstream 193717 31169219 ~ 31170874 (+)
XLOC_025449 NA non-coding downstream 256307 31231809 ~ 31239563 (+)
XLOC_025455 BX324157.1 non-coding downstream 813019 31788521 ~ 31788637 (+)
XLOC_025458 NA non-coding downstream 942660 31918162 ~ 31919131 (+)

Expression



Co-expression Network