XLOC_025441 (prf1.1)


Basic Information

Item Value
gene id XLOC_025441
gene name prf1.1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 30980852 ~ 30988333 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050175
TTTTTTCTATCTTGAAATCTTTTATTTAGCGGTTTGCTTGCATGCCACTGAGAAATTAAAGACGGATAGCATGTAGAAAATGACTTATAAAAGGAACATTTCAACTGTGAACTTTGGCAACTAGTTGTCAGTGGGTTTAAAAAGGTTAAAACTCAAAATGCCTTGTTTTTTCACAGGAAAGAAGAGCATCCATACACATTTCCTCCACTCATTGACAGAGATGAGGGCTGGATTGTTTTTTTACCTTCTCTTGCCTGTTGTGCAGTCCTGCACTAAAGGTAAACCCAAAGAGTGTGAAGAAGCAACCTTTGCACCCGGATCTAACCTGGCCGGAGAAGGATACGACGTGATCAAGATGCAGCGCAAGGGAGCTTTTGTCATCAACACAGACGTCTGGAGGCAAAAGGACAAATCCTGCACCCTCTGCAAGAACCCCTATATGGACGGAGCTTTACAAAAGCTTCCTCTGTCAGTGGTGGACTGGAGAACCAGCCAAAAATGCACCGTGAAAGTCTCCAGTTCTCTATACCATTCCAGCGAGGACCTGGTGAGCTCCAGCGCCTCCTCTATTGAGAACAACTGGGGTGCAAGTTTGGGGATAGAGGCTAAAAAAACAACAGGCTCGATAGTTTTGGCAGGAAGCAAGTCAAAGCTTGCAGAGTACTCAATGGAGAAGACCAAAAAAGACAAGTTCAACTTTGCAAGTCAAAGTATTTCCTGTGCTTATTACAGCTATCGAGTCTCCAACAAGCCTGTTCTCCATCCTGAGTTCAAACGATCTGTGAAGGAGCTTCCCAAGACATACAACCTTCAATTCAAGCCGCGTTTCTACAAGTTCATTAACACCTTTGGAACCCATTACATCACAAAGGTAACTCTTGGCGGAAACGTGCACTCAGTGACCAGTATCAGACAATGTGAAACCGCTCTTCAGGGCTTAAGCACAGACGAAGTAAAGGCCTGCTTGGATTTGGAGGCAAATATGAGCATTCTTGGCAAAGCAGACATGAAAGCCGAATCAAAACACTGTAGTCAAAATCAGGACAAAACAGAGAGCAAAACCAGCTTCTCCAGCCGCTTCAATGACAGGCTGACCGAGGTCACCGGAGGTCACACCACAGAGCCCGAGCTCCTTTTTTCAGGAGGGAAAGACCCATCAGCTTACAAAGAATGGCTGGCGTCCCTGCCGCAAAACCCAGATGTGATTTCTCACTCTCTGGAGTCCCTGCACGAGCTGATCCCCACCAAATACCCAGTGCGCAAACACATGCGCCAAGCCATCCACGACTACATCCTGGAAAATTCCCTTTGGAGGAACTGCACCGACCCCTGCACTAATGGCGTCAAAACCAACCCAAACAATCCATGTGTCTGCACTTGCCACAACAAACCCGGAATCACACCAGACTGTTGCCCGTCCAAACGTGGACTCTCTCGGGTGCAGGTCACGGTCGTTAAGGCTCAAGATCTTTGGGGTGACACAACCACAGCGACCGATGGCTATGTTAAAGTGTTCGACAAAAATAACGTGAAGATTGGATCCACAAATATGATACCGAATAACAATTCACCCTACTGGGGGCAAACCTTCGATCTGGGTGATGTCATCCTGGCAGAGAATGACAATATCAAACTGGAGGTGTGGGATGAAGACAGTAAATGGGATGACGATTTGTTGGGAACCTGTCAGGTAGCCATAAAAGTAGATCAGAGTCAGACCTACAATTTCTGCAGTTTGAATCATGGTTTGCTCTATTACAATACAAAAGTGACATGCGCCCCCGGTTTGGCTGGCACCTATTGTGAAAAGTATGTGGGTTCCCCCATGAACTTTCACCTGGAGAAGGTTTACGTGTCTCGAAATGCACGACCTGTGCCACCAGAAATACTTTTAAGCCATGGAGTGCTTCTGGACAGACTTTACGTATATCACAAGACAAATTACAATAATACAGTTTTGTAGATACTTTGGCTCTGGATGAGATTATGTGGCTATTTGCAATATATCCTGATTCTTGCTTGTATTTATTACTATACGATTATTATATTTAATCTAATTCTTGCATAATACATATTTAGGCTATACCATtcttagaagttttttttttttgcatatgtctGGGTGATTCTACAATTGCAGTAAGGGTGTACTCAATACTATGCTattgtaccgtg

Function

symbol description
prf1.1 Predicted to enable calcium ion binding activity. Predicted to act upstream of or within cytolysis. Is expressed in gill; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; familial hemophagocytic lymphohistiocytosis 2; human immunodeficiency virus infectious disease; multiple sclerosis; and non-Langerhans-cell histiocytosis. Orthologous to human PRF1 (perforin 1).

GO:

id name namespace
GO:0019835 cytolysis biological_process
GO:0005509 calcium ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-111212-2 Predicted to enable calcium ion binding activity. Predicted to act upstream of or within cytolysis. Is expressed in gill; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including Crohn's disease; familial hemophagocytic lymphohistiocytosis 2; human immunodeficiency virus infectious disease; multiple sclerosis; and non-Langerhans-cell histiocytosis. Orthologous to human PRF1 (perforin 1).

Ensembl:

ensembl_id ENSDARG00000030394

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050175 True 2175 mRNA 0.45 4 30980852 30988333

Neighbor

gene id symbol gene type direction distance location
XLOC_025440 prf1.9 coding upstream 5350 30968176 ~ 30975502 (+)
XLOC_025439 NA coding upstream 32398 30943288 ~ 30948454 (+)
XLOC_025438 cldni coding upstream 53850 30921246 ~ 30927002 (+)
XLOC_025437 NA coding upstream 72726 30907892 ~ 30908126 (+)
XLOC_025436 NA coding upstream 107692 30868418 ~ 30873160 (+)
XLOC_025442 cox6a2 coding downstream 51590 31039923 ~ 31042102 (+)
XLOC_025443 si:dkey-66i24.7 coding downstream 70131 31058464 ~ 31060609 (+)
XLOC_025444 si:dkey-66i24.8 coding downstream 99176 31087509 ~ 31090561 (+)
XLOC_025445 si:dkey-66i24.9 coding downstream 105122 31093455 ~ 31097530 (+)
XLOC_025446 NA coding downstream 109600 31097933 ~ 31105653 (+)
XLOC_025429 BX649540.1 misc upstream 731816 30248739 ~ 30249036 (+)
XLOC_025435 NA non-coding upstream 285045 30694174 ~ 30695807 (+)
XLOC_025434 NA non-coding upstream 325294 30643162 ~ 30655558 (+)
XLOC_025447 NA non-coding downstream 180886 31169219 ~ 31170874 (+)
XLOC_025449 NA non-coding downstream 243476 31231809 ~ 31239563 (+)
XLOC_025455 BX324157.1 non-coding downstream 800188 31788521 ~ 31788637 (+)
XLOC_025458 NA non-coding downstream 929829 31918162 ~ 31919131 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000069_02862381_02864927 PRF1.1 coding CI01000069 null 2861654 ~ 2864993 (+)