XLOC_025489 (unc119.2)



Basic Information


Item Value
gene id XLOC_025489
gene name unc119.2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 32594357 ~ 32619634 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00050257
ACTTCTGACAGCTGATCCTGGACTTCGTAGAACTATTTTTGATGGCGGACAGAAAATAGAAGAGGTCACCGAGACACAGTGGACCAGAGAAGAGCTGAGTGTAATCACACAGAGAGCCAGAGAACAGATGAACCTGAGTTAGTTAGTTTACAGCCGTGACGAATACTATTCAGACACCAGGTTTTAGATGGATGGTGAAGGTGTGAAGGAGCCGCACAGTGAAGATGAGATGGAGCACGAGTTATCCTCTGATGACCAAGCAGAGAGAGATGAGGATGAAGCTGAAGACGTTGAGGAGGAGATGGCAGATGCACAGGACAGAGGAGGCCTGAGGAACGTGGAGGACTGGAATGGCTTTATTTCTGGAGGACCAGCGGCTGAAGAAGAGGCGCTGCTGGACTGGAAACCCGGCGACCCTGTGACTCCTCAGTATGTCCTTAGACTGCCAGGATACACGGATGACTACATGTGCTCCCCAGAAGACAACATCTACAATATTAGCTTCTCACGCTTCAAAATAAGAGATCTGGAAGGTGGATGTGTCATCTTGGATCTAAAACGACATTGTCCAACAGAAATAAAGGATATGATAGAGCTGGATGCTGGCCGTTTCATTCAGTATCATTTCAGTCCAGCTTTTCTAAACCTCAGGGAGATTGGAGCCATGCTTGAGTTCACAGTGGGCGGAAAAGCAGTGAACAAGTTTCGTCTGATCGAGAAGCATTACTTCAGGGATCTTCTGCTCAAGACGTTTGACTTTGAGATCGGCTTCTGTATCCCACACAGCAGAAACACCTGTGAACACATCTACTGCTTACCAGACCTGGATCCACACACCATTGAGGAGATGATCAATCACCCTTTTGAGACGCGCTCAGACAGCTTCTACTTCGCCAACAACACGCTGATCATGCATCATAAGGCTGAATATTCCTTCAGTCAGGGGCTGCAGAACAACCAAAACCAAAGCTAGACTCTTCGCCATCAGGCAGTGTGAACCACAGCAATtctaaataataaacacaatagTGCTGTACATTGGGTTTTGTAAATCATATGCATGAACTAGACAAAGACATGTCTTTGTTACCTTGTGTTTTTGCTTGGGAGATGTTGTGTTGCTTTCACAgtattaacataataaaacaaatgaaaaattca
>TCONS_00050258
ATGGATGGTGAAGGTGTGAAGGAGCCGCACAGTGAAGATGAGATGGAGCACGAGTTATCCTCTGATGACCAAGCAGAGAGAGATGAGGATGAAGCTGAAGACGTTGAGGAGGAGATGGCAGATGCACAGGACAGAGGAGGCCTGAGGAACGTGGAGGACTGGAATGGCTTTATTTCTGGAGGACCAGCGGCTGAAGAAGAGGCGCTGCTGGACTGGAAACCCGGCGACCCTGTGACTCCTCAGTATGTCCTTAGACTGCCAGGATACACGGATGACTACATGTGCTCCCCAGAAGACAACATCTACAATATTAGCTTCTCACGCTTCAAAATAAGAGATCTGGAAGGTGGATGTGTCATCTTGGATCTAAAACGACATTGTCCAACAGAAATAAAGGATATGATAGAGCTGGATGCTGGCCGTTTCATTCAGTATCATTTCAGTCCAGCTTTTCTAAACCTCAGGGAGATTGGAGCCATGCTTGAGTTCACAGTGGGCGGAAAAGCAGTGAACAAGTTTCGTCTGATCGAGAAGCATTACTTCAGGGATCTTCTGCTCAAGACGTTTGACTTTGAGATCGGCTTCTGTATCCCACACAGCAGAAACACCTGTGAACACATCTACTGCTTACCAGACCTGGATCCACACACCATTGAGGAGATGATCAATCACCCTTTTGAGACGCGCTCAGACAGCTTCTACTTCGCCAACAACACGCTGATCATGCATCATAAGGCTGAATATTCCTTCAGTCAGGGGCTGCAGAACAACCAAAACCAAAGCTAG

Function


symbol description
unc119.2 Predicted to enable lipid binding activity. Acts upstream of or within optomotor response and regulation of axon extension involved in axon guidance. Predicted to be active in intercellular bridge and microtubule cytoskeleton. Is expressed in epiphysis; eye photoreceptor cell; olfactory pit; otic vesicle; and retina. Used to study cone-rod dystrophy. Human ortholog(s) of this gene implicated in immunodeficiency 13. Orthologous to human UNC119 (unc-119 lipid binding chaperone).

GO:

id name namespace
GO:1900186 negative regulation of clathrin-dependent endocytosis biological_process
GO:2001287 negative regulation of caveolin-mediated endocytosis biological_process
GO:0071632 optomotor response biological_process
GO:0048841 regulation of axon extension involved in axon guidance biological_process
GO:0007601 visual perception biological_process
GO:0007399 nervous system development biological_process
GO:0061098 positive regulation of protein tyrosine kinase activity biological_process
GO:0000281 mitotic cytokinesis biological_process
GO:0042953 lipoprotein transport biological_process
GO:0005813 centrosome cellular_component
GO:0000922 spindle pole cellular_component
GO:0045171 intercellular bridge cellular_component
GO:0051233 spindle midzone cellular_component
GO:0008289 lipid binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-7635 Predicted to enable lipid binding activity. Acts upstream of or within optomotor response and regulation of axon extension involved in axon guidance. Predicted to be active in intercellular bridge and microtubule cytoskeleton. Is expressed in epiphysis; eye photoreceptor cell; olfactory pit; otic vesicle; and retina. Used to study cone-rod dystrophy. Human ortholog(s) of this gene implicated in immunodeficiency 13. Orthologous to human UNC119 (unc-119 lipid binding chaperone).

Ensembl:

ensembl_id ENSDARG00000004459

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00050257 False 1161 mRNA 0.45 6 32594357 32619634
TCONS_00050258 True 786 mRNA 0.48 5 32615889 32619446

Neighbor


gene id symbol gene type direction distance location
XLOC_025488 si:ch73-248e21.1 coding upstream 10983 32571929 ~ 32583374 (+)
XLOC_025487 FP236454.1 coding upstream 22986 32571309 ~ 32571371 (+)
XLOC_025486 pax10 coding upstream 28474 32546499 ~ 32565883 (+)
XLOC_025485 nosip coding upstream 57979 32532000 ~ 32536378 (+)
XLOC_025484 si:ch73-367p23.2 coding upstream 63353 32526263 ~ 32531004 (+)
XLOC_025490 mmp25a coding downstream 941 32620575 ~ 32629489 (+)
XLOC_025491 srrm2 coding downstream 11738 32631372 ~ 32650278 (+)
XLOC_025492 NA coding downstream 32063 32651697 ~ 32658436 (+)
XLOC_025493 si:dkey-16l2.16 coding downstream 42131 32661765 ~ 32669219 (+)
XLOC_025494 rnf25 coding downstream 51512 32671146 ~ 32680126 (+)
XLOC_025429 BX649540.1 misc upstream 2345321 30248739 ~ 30249036 (+)
XLOC_025481 CR936975.1 non-coding upstream 117072 32474661 ~ 32477285 (+)
XLOC_025475 NA non-coding upstream 246864 32346134 ~ 32347493 (+)
XLOC_025473 NA non-coding upstream 297354 32293773 ~ 32297003 (+)
XLOC_025458 NA non-coding upstream 675226 31918162 ~ 31919131 (+)
XLOC_025505 NA non-coding downstream 357248 32976882 ~ 33029027 (+)
XLOC_025506 NA non-coding downstream 421673 33041307 ~ 33043550 (+)
XLOC_025507 NA non-coding downstream 424010 33043644 ~ 33045022 (+)
XLOC_025508 CR392003.1 non-coding downstream 426249 33045883 ~ 33048390 (+)

Expression



Co-expression Network