XLOC_025497 (fus)


Basic Information

Item Value
gene id XLOC_025497
gene name fus
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 32698424 ~ 32711280 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050275
TCGACACTGCATCATCACCGTCATCGTCAGTCTTTCCGCACAGTTGCGCAGTTTACCGAAGGCGACTGTACGTATAACACCTCAGAAATTGTTATTCTGCATCATTTCTAAAAGGATTTTAAGCCCAAACATGGCGTCAAATGATTATGGCCAAACCTCAAGCCATGGCTATGGGGGTTATGGAGGACAGTCCGGTCAAAGCTACAGCCAACCTTCTGCCCAGAACTACAGTCAGCAGAGCTATGGAGGATACAACCAAAGCTCAGAGAGCAGCTCCGCTCCTTATAATCAGGGAGGATACAGCTCCAACTATGGACAGTCCCAGTCAGGAGGATATGGATCTCAAGCCCCTTCTCAAGGCTACAGTCAGTCCAGTCAGTCGTATAGCTCTGGTGGCTACAGTAACACCAGCCAGCCTCCACCAGCTCAAAGCGGAGGCTACAGCCAGCAGTCCTCTTATTCTGGCTATAACCAGTCTTCTCCTGCATCTGCCCCTGGTGGCTATAGCAGCAGCTCTCAGTCGTCTGGCTAcggtcagcagcagcagcagagtgGAGGTGGGTATGGAGGCAGTGGTGGTCAGTCTGGAGGATATGGGAGCAGTGGAGGCCAGAGCAGTGGATTTGGGGGTAGCGGAGGCCAACACCAGTCCTCTCAGTCTGGAGGAGGGTCTTACAGCCCATCTCCTAACTACAGCTCCCCTCCACCACAAAGCTATGGGCAACAAAGTCAGTACGGACAGGGAGGTTACAACCAAGATAGCCCACCAATGAGTGGTGGGGGAGGTGGTGGGGGCTATGGTGGTCAGGATGGCGGATACAGCCAGGATGGTAGAGGTGGACGTGGCCGTGGAGGTGGCTTTGGAGGTCGAGGAGCGGGTGGGTTTGACAGGGGTGGTCGTGGAGGACCCCGTGGCAGAGGAGGAATGGGAATGGGCGATCGTGGAGGATTCAATAAGTTTGGTGGGCCCAGGGATCATGGAGCTGGTGGGCCCAATATGCAGGAGCAGGATAACTCTGACAACAACACCATCTTTGTACAAGGTCTTGGAGACGACTATACTGTGGACTCTGTTGCAGACTACTTTAAACAGATCGGCATCATCAAGGTGAATAAGAAGACAGGATTGCCCATGATTAATCTGTATACAGACAGAGAGACGGGGAAGCTTAAAGGGGAGGCTACTGTTTCCTTTGATGACCCTCCTTCAGCAAAAGCAGCCATTGATTGGTTTGATGGTAAAGATTTTAATGGAAATCCAATCAAGGTGTCCTTCGCCACCCGCAGAGCTGAGTTTGGTCGTGGTGGCAGCAGCGGTGGCATGAGAGGTGGCCGTGGTCGAGGAGGGCCAATGGGGCGTGGGGGATTTGGGGGTGGcagaggtggtggtggtggtggtggtggtttcCAAGGCAACAATGGTGGTGGTAGTGGCAACGGCGGCGGTCAGCAAAGAGCAGGAGACTGGAAGTGTTCAAACCCTTCATGTGGAAATTTGAACTTCTCATGGCGAAACGAGTGCAATCAGTGCAAAGAACCCAAACCGGAAGGAAGTGGAGGAGGAATGTCCCCGATGGGAGGTGGTTTTGGTGGAGAGCGGGGCAGAAGTGGCTTCGATCGAGGTGGTTTCCGTGGTCGTGGTGGTGATCGAGGAGGTTtcagaggaggaagaggaggagatcGTGGAGGATTTGGACCTGGAAAGATGGACTCGAGGGGTGACCACAGACATGACCGCAGAGACCGCCCTTACTAACATCTCTTTTGTCTAAATCCGACTTTTAATTCTACGTGGGACCAGTAATCAATCCACTTTgacaaatttttcaaaaaaatttttttttttagttttgtgttgtatgttgttaaattaagttttttcagttatgctattaatattattattattattttatgttttttacgATTTTCTGTATAATCTCATATTGTTAATtatgaatatttgtttttattttctttccctGAATTTGCTGGCGGTTAGGCCACCTTAGTACTATTTGTGCAATTTATTCAATGTACTTTCTTTGATCTTTTTTGAAAGatgtgaattaaaatgaaaaccattTGAAAGAA
>TCONS_00050276
tgacaagagtgtctgttgttttttctgtttcgAAATTAGCTTTTGTGGAATACAGGATAAGAGGCTAATTGCACTATGAGCGCACTGTCATTGTCATGTTTCAGTAGTGTTCAGTGCTGATTTCATTTATTCCTTAAAAAAATAGTGAATGGTAAATGAATGGGTGCAAAGTGGTATTCAGTTAGAGGTTGTCTTTGTTTGCCTTTCACCAGATACCTACAACTAAAACCAGCCTACCTAACAcaccaataacaacaacaaaagaccCAAAAGCAGAACGTTGAAGTATGATTGAACGGGTTTTGCAGGAATTTATTTGGATGACTATTGCAAGGTTTTCCGCTTTCCAGAAAATTCAAGATGTGTGATGTAAAAGCCAGTACATGGAGTTGTCTGATATAAATTCAGGTTTTCTCATGAGGATGAATCATGCTGCAGTTGCTGGTATGGGAGGACAGATTCTTCCACTTAAGTCCTTGGAcatatttaaaacctttaaagACCAATTCCATCGAGTGTTGGTTAGAAACAATGCGTATGGTGCTTTTGGTATAACTCTCATACATCCGGTGAGGTTTTCGAAACGTGGAgcataaattttatataattgatAGTACAGATGTGCATTATGAGAAGAAGGAAAGTCAAAGGATGAAAAATGTAGAAATGTTTGCACACTGCGTTGCTCTGTACATGCATAATATTAATAAGTGTTCCTTTCACTTAAAGGGCCCAGGGATCATGGAGCTGGTGGGCCCAATATGCAGGAGCAGGATAACTCTGACAACAACACCATCTTTGTACAAGGTCTTGGAGACGACTATACTGTGGACTCTGTTGCAGACTACTTTAAACAGATCGGCATCATCAAG

Function

symbol description
fus Predicted to enable RNA binding activity and transcription coregulator activity. Acts upstream of or within axon extension. Predicted to be active in nucleus. Is expressed in gut; muscle; nervous system; and trunk. Used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 6; essential tremor 4; liposarcoma; and neurodegenerative disease. Orthologous to human FUS (FUS RNA binding protein).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0048675 axon extension biological_process
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003712 transcription coregulator activity molecular_function
GO:0003723 RNA binding molecular_function

KEGG:

id description
ko03040 Spliceosome
ko03015 mRNA surveillance pathway
ko05202 Transcriptional misregulation in cancer
ko05014 Amyotrophic lateral sclerosis
ko05022 Pathways of neurodegeneration - multiple diseases
ko03041 Spliceosome

ZFIN:

id description
ZDB-GENE-040426-1010 Predicted to enable RNA binding activity and transcription coregulator activity. Acts upstream of or within axon extension. Predicted to be active in nucleus. Is expressed in gut; muscle; nervous system; and trunk. Used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 6; essential tremor 4; liposarcoma; and neurodegenerative disease. Orthologous to human FUS (FUS RNA binding protein).

Ensembl:

ensembl_id ENSDARG00000037968

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050275 False 2094 mRNA 0.49 15 32698424 32711280
TCONS_00050276 True 872 lncRNA 0.39 2 32707140 32708110

Neighbor

gene id symbol gene type direction distance location
XLOC_025496 si:dkey-16l2.17 coding upstream 1832 32689707 ~ 32696592 (+)
XLOC_025495 kat8 coding upstream 9096 32681274 ~ 32689328 (+)
XLOC_025494 rnf25 coding upstream 18298 32671146 ~ 32680126 (+)
XLOC_025493 si:dkey-16l2.16 coding upstream 29205 32661765 ~ 32669219 (+)
XLOC_025492 NA coding upstream 39988 32651697 ~ 32658436 (+)
XLOC_025498 setd1a coding downstream 2877 32714157 ~ 32742578 (+)
XLOC_025499 hsd3b7 coding downstream 32666 32743946 ~ 32778250 (+)
XLOC_025500 tbc1d10b coding downstream 78325 32789605 ~ 32811362 (+)
XLOC_025501 cd2bp2 coding downstream 120762 32832042 ~ 32842383 (+)
XLOC_025502 prr14 coding downstream 131514 32842794 ~ 32855371 (+)
XLOC_025429 BX649540.1 misc upstream 2449388 30248739 ~ 30249036 (+)
XLOC_025487 FP236454.1 non-coding upstream 127053 32571309 ~ 32571371 (+)
XLOC_025481 CR936975.1 non-coding upstream 221139 32474661 ~ 32477285 (+)
XLOC_025475 NA non-coding upstream 350931 32346134 ~ 32347493 (+)
XLOC_025473 NA non-coding upstream 401421 32293773 ~ 32297003 (+)
XLOC_025505 NA non-coding downstream 265602 32976882 ~ 33029027 (+)
XLOC_025506 NA non-coding downstream 330027 33041307 ~ 33043550 (+)
XLOC_025507 NA non-coding downstream 332364 33043644 ~ 33045022 (+)
XLOC_025508 CR392003.1 non-coding downstream 334603 33045883 ~ 33048390 (+)
XLOC_025509 NA non-coding downstream 482088 33193368 ~ 33194715 (+)

Expression


Co-expression Network