XLOC_002567 (MACIR)


Basic Information

Item Value
gene id XLOC_002567
gene name MACIR
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 6765109 ~ 6775271 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004772
GGGGTCGACAGCAGACATCGGGAGCTGCTCTCCTCCGACTGGGATCTCGTCTATGGTTTTCTCAAGCCAAGGGGTGCAGTTTTTCCGAACAGCCAGGTCATGTCATTAAAGATGGAAATGGATGCCAGTGGAGCGTCCAGGGCACCCATATCTGTTCTGCCTGCAGCTGAGGTCAAAAGCACCCTGAAGCCTGAAGCCGATAAACCCCGCTGCTCCAGCACTCCCTGCTCCCCCATTAAAAGTACTGTCTCAGGATACCAGATCCTTCACATGAACTCCAACTATCTCGTGGGCTTTACAACTGGCGAGGAGCTTCTCAAATTAGCCCAGAAATGGTCAAGTCCTGACAGCAGCAACACAGAGGCCTTGCCCAGCCCCATTAAAAAGCCTGTGGATTTAGGTCTGCACCGAGCCTCACGGATTTACAAAGCCAAAAGCCGTTACTACCAACCGTACGACATCCCAGCCGTCAATGGGCGAAGGAGGCGGCGCATGCCCAGCTCAGGCGACAGCTGCCTGAAGTCCATAGTGAGCGGGGAGCCAAGCAAGGCTTTACACGGGCCCCTGCCTCTCTGCCTGTTGAAGGGCAAACGGGTTTACTCCAAGTCCCTGGACTACCTCAACCTGGACAAGATGAGCCTCAGGGAGCCGGTGGACACAGAGGTGCTGCAGTACCAGCTGCAGCATCTGAATTTGCGGGGTGAGCGCGTATTCACCCGCAACAAAACATGAGTTCTCACGTCAACCTTCACCTGCCCACGGTTGTCTGACT

Function

symbol description
macir Involved in cilium assembly and regulation of macrophage migration. Acts upstream of or within Kupffer's vesicle development; negative regulation of macrophage chemotaxis; and regulation of wound healing. Predicted to be located in ciliary transition zone and cytoplasm. Orthologous to human MACIR (macrophage immunometabolism regulator).

GO:

id name namespace
GO:0006954 inflammatory response biological_process
GO:1900016 negative regulation of cytokine production involved in inflammatory response biological_process
GO:0050728 negative regulation of inflammatory response biological_process
GO:0015031 protein transport biological_process
GO:0010760 negative regulation of macrophage chemotaxis biological_process
GO:0010764 negative regulation of fibroblast migration biological_process
GO:0070121 Kupffer's vesicle development biological_process
GO:0061041 regulation of wound healing biological_process
GO:0030030 cell projection organization biological_process
GO:0060271 cilium assembly biological_process
GO:0042995 cell projection cellular_component
GO:0035869 ciliary transition zone cellular_component
GO:0005929 cilium cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003674 molecular_function molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-081022-94 Involved in cilium assembly and regulation of macrophage migration. Acts upstream of or within Kupffer's vesicle development; negative regulation of macrophage chemotaxis; and regulation of wound healing. Predicted to be located in ciliary transition zone and cytoplasm. Orthologous to human MACIR (macrophage immunometabolism regulator).

Ensembl:

ensembl_id ENSDARG00000093498

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004772 True 772 mRNA 0.55 2 6765109 6775271

Neighbor

gene id symbol gene type direction distance location
XLOC_002566 BX511100.4 coding downstream 37995 6725657 ~ 6727114 (-)
XLOC_002565 NA coding downstream 69777 6693514 ~ 6695332 (-)
XLOC_002564 BX511100.3 coding downstream 85623 6677673 ~ 6679486 (-)
XLOC_002563 BX511100.6 coding downstream 102241 6661059 ~ 6662868 (-)
XLOC_002562 BX511100.5 coding downstream 125942 6611075 ~ 6639167 (-)
XLOC_002568 ppip5k2 coding upstream 5852 6781123 ~ 6867282 (-)
XLOC_002569 sh2d4a coding upstream 192022 6967293 ~ 6976645 (-)
XLOC_002570 CABZ01061993.1 coding upstream 234103 7009374 ~ 7009490 (-)
XLOC_002571 NA coding upstream 275054 7050325 ~ 7061537 (-)
XLOC_002572 NA coding upstream 462973 7238244 ~ 7253898 (-)
XLOC_002575 BX537303.2 non-coding upstream 736737 7512008 ~ 7512123 (-)
XLOC_002585 BX294661.1 non-coding upstream 1095356 7870627 ~ 7892684 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000304_01323957_01324596 C16H5ORF30, CUNH5ORF30 coding CI01000304 null 1323957 ~ 1326322 (+)
mexican tetra (Astyanax mexicanus) G303307 cunh5orf30,zgc:194281,c16h5orf30,LOC107564120,LOC107740794,LOC107670048,LOC107665462,LOC107715868 misc NW_019172836.1 APWO02000054.1 365993 ~ 383873 (+)